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*  ParaHox - Wikipedia
The ParaHox gene cluster is an array of homeobox genes (involved in morphogenesis, the regulation of patterns of anatomical development) from the Gsx, Xlox (Pdx) and Cdx gene families. These genes were first shown to be arranged into a physically-linked chromosomal cluster in amphioxus, an invertebrate with a single member of each of the three gene families. All the ParaHox genes in the amphioxus genome are therefore in the ParaHox gene cluster. In contrast, the human genome has six ParaHox genes (GSX1, GSX2, PDX1, CDX1, CDX2, CDX4), of which three genes (GSX1, PDX1 (=IPF1), CDX2) are physically linked to form a human ParaHox gene cluster on chromosome 13. Mouse has a homologous ParaHox gene cluster on chromosome 5. The other three human ParaHox genes are remnants from duplicated ParaHox gene clusters that were generated in the 2R genome duplications at the base of vertebrate evolution. Some vertebrates, notably chondrichthyan fish and coelacanths, have retained an additional ParaHox gene ...
  https://en.wikipedia.org/wiki/ParaHox
*  IL1F10 - Wikipedia
Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. GRCh38: Ensembl release 89: ENSG00000136697 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000046845 - Ensembl, May 2017 "Human PubMed Reference:". "Mouse PubMed Reference:". Bensen JT, Dawson PA, Mychaleckyj JC, Bowden DW (Dec 2001). "Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14". J Interferon Cytokine Res. 21 (11): 899-904. doi:10.1089/107999001753289505. PMID 11747621. Taylor SL, ...
  https://en.wikipedia.org/wiki/IL1F10
*  Plus it
Prostate cancer (PCa) is the 2nd leading cause of cancer death among men in the U.S. No accurate biomarkers exist and therapeutic options are limited for advanced PCa. MicroRNAs (miRNAs), small non-coding RNAs, act as negative regulators of gene expression. MiRNAs have recently emerged as promising therapeutic tools for cancers. It is poorly understood how they function to promote cancer progression. We found miR-888 was involved with PCa progression. miR-888 belongs to a genomic cluster on human chromosome Xq27.3, linked to hereditary PCa. I hypothesized additional members of this cluster (miR-892c, -890, -892a, -892b, -891b, -891a) function to promote PCa progression. Our lab profiled miR-888 cluster expression in paired syngenic human PCa cell lines (RWPE1 & WPE1-NB26, LNCaP & C4-2, PC3-N & PC3-ML) differing in metastatic status and androgen response. We noted that the miR-888 cluster was preferentially elevated in metastatic PC3-ML and under-expressed in non-aggressive PC3-N cells. I ...
  http://cancerres.aacrjournals.org/content/77/13_Supplement/2523
*  STORRE: Finding approximate gene clusters with Gecko 3
Gene-order-based comparison of multiple genomes provides signals for functional analysis of genes and the evolutionary process of genome organization. Gene clusters are regions of co-localized genes on genomes of different species. The rapid increase in sequenced genomes necessitates bioinformatics tools for finding gene clusters in hundreds of genomes. Existing tools are often restricted to few (in many cases, only two) genomes, and often make restrictive assumptions such as short perfect conservation, conserved gene order or monophyletic gene clusters. We present Gecko 3, an open-source software for finding gene clusters in hundreds of bacterial genomes, that comes with an easy-to-use graphical user interface. The underlying gene cluster model is intuitive, can cope with low degrees of conservation as well as misannotations and is complemented by a sound statistical evaluation. To evaluate the biological benefit of Gecko 3 and to exemplify our method, we search for gene clusters in a dataset ...
  http://dspace.stir.ac.uk/handle/1893/24323
*  Interleukin-1 receptor type 2
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012 ...
  https://pharos.nih.gov/idg/targets/P27930
*  IL36B - Wikipedia
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.[8]. ...
  https://en.wikipedia.org/wiki/IL36B
*  Alnu 00040 : CDS information --- DoBISCUIT
18940666] Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis. (Chem Biol. , 2008 ...
  http://www.bio.nite.go.jp/pks/feature/view/Alnu_00040
*  Gene Expression Literature Detail
J:29934 Williams R, Lendahl U, Lardelli M, Complementary and combinatorial patterns of Notch gene family expression during early mouse development. Mech Dev. 1995 Nov;53(3):357-68 ...
  http://www.informatics.jax.org/gxdlit/key/2966
*  Plus it
Metastasis and progression, reflected by higher migration and longer cell survival, are major contributing factors in making cancers the leading cause of death worldwide. Cancer cells exhibit higher migration rates and greater cell viability facilitated by actin binding protein-mediated cytoskeletal remodeling and secondary messengers (cAMP and/or cGMP) signaling. Studies have shown that docosahexaenoic acid (DHA), a poly unsaturated fatty acid, inhibits cancer cell metastatic phenotype. Moreover, miRNA-17∼92 cluster has been reported to be highly expressed in metastasis. Therefore, we put forward a hypothesis that DHA will induce changes in actin binding protein dynamics and miRNA-17∼92 cluster expression to inhibit cancer cell migration and viability. Non-cance (MLE12) and cancer (A549) cells were treated with 8-Br-cAMP and/or DHA for 30 min, 3h, 6h and 24h. Actin binding proteins (profilin, cofilin, vimentin and gelsolin) and miRNA-17∼92 cluster expression were analyzed by western blot ...
  http://cancerres.aacrjournals.org/content/75/15_Supplement/1444
*  IL18R1 - Wikipedia
The interleukin-18 receptor 1 (IL-18R1) is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is its human gene. IL18R1 is also known as CDw218a (cluster of differentiation w218a). The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Interleukin-18 receptor GRCh38: Ensembl release 89: ENSG00000115604 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000026070 - Ensembl, May 2017 "Human PubMed Reference:". "Mouse PubMed Reference:". "Entrez Gene: IL18R1 interleukin 18 receptor 1". Sergi B, Penttila I (2005). ...
  https://en.wikipedia.org/wiki/IL18R1
*  Difference between revisions of "CH391L/S13/Refactoring Operons" - OpenWetWare
Prokaryotic genes associated with a specific function are often grouped together in contiguous regions of the genome known as gene clusters [1]. Many of the functions encoded in these clusters are of interest to synthetic biology. Unfortunately, gene clusters are frequently subject to complex and highly redundant host regulation [1]. However, through a process known as "refactoring," gene clusters can be recoded to systematically eliminate native regulation [2]. This process of refactoring aims to reduce the overall complexity of genetic systems and allows them to be tailored for a particular purpose. The term "refactoring" is borrowed from computer science and refers to the alteration of a program's underlying code without changing its functionality [2]. This term was first applied in biology to describe the top-down approach of simplifying the phage T7 genome [3], but it is used here to refer to the bottom-up approach of eliminating native regulation of gene clusters and replacing it with ...
  https://openwetware.org/wiki/?title=CH391L/S13/Refactoring_Operons&diff=691657&oldid=691519
*  CH391L/S13/Refactoring Operons - OpenWetWare
Prokaryotic genes associated with a specific function are often grouped together in contiguous regions of the genome known as gene clusters [1]. Many of the functions encoded in these clusters are of interest to biotechnology [2]. Unfortunately, gene clusters are frequently subject to complex and highly redundant host regulation. However, through a process known as "refactoring," gene clusters can be recoded to systematically eliminate native regulation [2]. This process of refactoring aims to reduce the overall complexity of genetic systems and allows them to be tailored for a particular purpose. The term "refactoring" is borrowed from computer science and refers to the alteration of a program's underlying code without changing its functionality [2]. This term was first applied in biology to describe the top-down approach of simplifying the phage T7 genome [3], but it is used here to refer to the bottom-up approach of eliminating native regulation of gene clusters and replacing it with ...
  https://openwetware.org/wiki/?title=CH391L/S13/Refactoring_Operons&oldid=691503
*  Difference between revisions of "CH391L/S13/Refactoring Operons" - OpenWetWare
Prokaryotic genes associated with a specific function are often grouped together in contiguous regions of the genome known as gene clusters [1]. Many of the functions encoded in these clusters are of potential interest to synthetic biology. Unfortunately, gene clusters are frequently subject to complex and highly redundant host regulation [1]. Furthermore, there may be no laboratory conditions known that allow for expression of these clusters. However, through a process known as "refactoring," gene clusters can be recoded to systematically eliminate native regulation [2]. This process of refactoring aims to reduce the overall complexity of genetic systems and allows them to be tailored for a particular purpose. The term "refactoring" is borrowed from computer science and refers to the alteration of a program's underlying code without changing its functionality [2]. This term was first applied in biology to describe the top-down approach of simplifying the phage T7 genome [3], but it is used here ...
  https://openwetware.org/wiki/?title=CH391L/S13/Refactoring_Operons&diff=693170&oldid=691476
*  CH391L/S13/Refactoring Operons - OpenWetWare
Prokaryotic genes associated with a specific function are often grouped together in contiguous regions of the genome known as gene clusters [1]. Many of the functions encoded in these clusters are of potential interest to synthetic biology. Unfortunately, gene clusters are frequently subject to complex and highly redundant host regulation [1]. Furthermore, there may be no laboratory conditions known that allow for expression of these clusters. However, through a process known as "refactoring," gene clusters can be recoded to systematically eliminate native regulation [2]. This process of refactoring aims to reduce the overall complexity of genetic systems and allows them to be tailored for a particular purpose. The term "refactoring" is borrowed from computer science and refers to the alteration of a program's underlying code without changing its functionality [2]. This term was first applied in biology to describe the top-down approach of simplifying the phage T7 genome [3], but it is used here ...
  https://openwetware.org/wiki/?title=CH391L/S13/Refactoring_Operons&oldid=691677
*  Chromosome 21 - Human-Chimpanzee Comparison
Scientists compared chimpanzee and human DNA sequences and detected two clusters on human chromosome 21 that suggest large, nonrandom regions of difference from the chimpanzee genome.
  http://www.godandscience.org/evolution/sld072.html
*  Cell Wall Genomics - Gene Families
We have segregated cell wall biogenesis into six distinct stages: substrate generation, polymer synthesis, secretion, assembly, rearrangement during development, and disassembly. Several gene families devoted to wall biogenesis representing these six stages have been identified, and many more of the unannotated and unknown genes remain to be examined. In this section we have provided the current knowledge of the relevant gene family structure and annotated them as to progress towards identification of availability of T-DNA insertional mutants, if mutants have been identified by other investigators, and other information gleaned from database searches. The next section on 'mutants' extends this list to EMS as well as T-DNA mutants that have been previously characterized. Each Arabidopsis entry will contain access directly to SIGnAL's T-DNA collection. Accession codes in red indicate that a SALK hit has been identified and is currently being directed to generation of homozygous lines and on to ...
  https://cellwall.genomics.purdue.edu/families/index.html
*  Selective Gene Expression in Multigene Families from Yeast to Mammals | Science Signaling
Thank you for your interest in spreading the word about Science Signaling.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
  http://stke.sciencemag.org/content/2004/256/re17.full
*  Introduction to the E2F Family: Protein Structure and Gene Regulation | SpringerLink
The E2F gene family was identified through several different types of investigations, including studies of viral oncogenes, positive and negative growth regulatory proteins, and cellular promoters. As described below and by Cobrinik, Cress and Nevins, and Adams and Kaelin (this volume), the E2F family (which includes at least seven members) has not only been implicated in controlling viral and cellular gene expression, but also is thought to play an important role in growth regulatory processes such as the G1 to S phase transition and programmed cell death. To understand how this gene family can mediate these important events it is first necessary to examine the structure and regulation of the individual family members. ...
  https://link.springer.com/chapter/10.1007%2F978-3-642-79910-5_1
*  PCDHA@ Gene - GeneCards | PCDHA@ Gene Cluster
Complete information for PCDHA@ gene (Gene Cluster), Protocadherin Alpha Cluster, Complex Locus, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=PCDHA@
*  Pyrlo 00140 : CDS information --- DoBISCUIT
17158935] Cloning and characterization of the pyrrolomycin biosynthetic gene clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. strain UC 11065. (Antimicrob Agents Chemother. , 2007 ...
  http://www.bio.nite.go.jp/pks/feature/view/Pyrlo_00140
*  Bond formation. The Km worth of XimA for xiamenmycin B was | rgsinhibitor.com
Bond formation. The Km value of XimA for xiamenmycin B was determined to be 474.38 mM. 6 Xiamenmycin Biosynthesis Gene Cluster Discussion Our study reported a
  http://rgsinhibitor.com/2017/06/28/bond-formation-the-km-worth-of-xima-for-xiamenmycin-b-was/
*  mouse Cnih protein Summary Report | CureHunter
mouse Cnih protein: Cnih - cornichon-like; member of the cornichon multigene family; C; involved in EGF signaling; RefSeq NM_009919
  http://www.curehunter.com/public/keywordSummaryC485558-mouse-Cnih-protein.do
*  Individual Members Listing
The following is a list of institutions and organizations represented by Individual Members as. To Search the ISSFAL Database of Members, you must be an ISSFAL Member and be granted access to the Members Only Section.. ...
  http://www.issfal.org/individual-members-listing
*  Trials of the Elite Four(AAMAYL/AdvanceShipping) - Page 3
This is the same as my fic on FF.net, though, to follow forum rules, I decided to combine some of the shorter chapters. Rating: G(may go up later, I dunno) Short Summary: The Elite Four opens a challenge to those who want to join their ranks. Ash is included, of course, but if he loses just once to a single member, everything that he stands for as a trainer will be taken away from him! DISCLAIMER:I don't own Pokemon or its related characters. -Might as well put in a Table of Contents.
  http://www.serebiiforums.com/showthread.php?234181-Trials-of-the-Elite-Four
*  Evidence for Cu(I) clusters and Zn(II) clusters in neuronal gr...
Evidence for Cu(I) clusters and Zn(II) clusters in neuronal growth-inhibitory factor isolated from bovine brain.: Neuronal growth-inhibitory factor (GIF), a cen
  https://www.mysciencework.com/publication/show/evidence-cu-i-clusters-zn-ii-clusters-neuronal-growth-inhibitory-factor-isolated-from-bovine-brain-45314f51