PLOS Computational Biology: Prediction of Protein Binding Regions in Disordered Proteins
Here, we present a general method to identify disordered binding regions from the amino acid sequence. Our method targets the ... The molecular recognition functions of IUPs/IDPs include regulatory and signaling interactions where binding to multiple ... Data Availability * Materials and Software Sharing * Ethical Publishing Practice * Authorship * Downloads and Translations ...http://journals.plos.org/ploscompbiol/article/figure?id=10.1371/journal.pcbi.1000376.t001
Initially, gene-specific sequence data were obtained by cloning and sequencing a 380-bp PCR product from two consecutive rounds ... The molecular processes underlying bile acid-independent exocrine activity of the liver are not well understood. By analogy ... 2000) The DNA sequence of human chromosome 21. The chromosome 21 mapping and sequencing consortium. Nature 405:311-319. ... Sequencing revealed this fragment to have a 400-bp overlap with the 5′-cap sequence-containing fragment. ...http://ajpgi.physiology.org/content/282/2/G233
Conserved alternative and antisense transcripts at the programmed cell death 2 locus | BMC Genomics | Full Text
The data were analyzed using LightCycler Software version 3.5.3 (Roche).. Polymerase chain reaction (PCR) and sequencing. Each ... Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Center for Applied Genomics, Prague, Czech Republic ... The sequences did not contain the sequence of the Pdcd2 constitutive exons (Fig. 2). By RT-PCR and sequencing, it was confirmed ... Furthermore, our data suggest that at least some of the cDNAs identified in the large-scale sequencing projects labeled as ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-8-20
Genomic variant #0000059648 - Shared database
Make a download or backup of the data you're about to edit. If uncertain, use the edit form of the data entries instead.. ... Remarks: remarks regarding the screening like WGS (whole genome sequencing), WES (whole exome sequencing, gene panel (incl. a ... MIP = Molecular Inversion Probe amplification. *MIPsm = singele molecule Molecular Inversion Probe amplification ... Make a download or backup of the data you're about to edit. If uncertain, use the edit form of the data entries instead.. ...https://databases.lovd.nl/shared/variants/0000059648
UCI Machine Learning Repository: Molecular Biology (Promoter Gene Sequences) Data Set: Support
View ALL Data Sets Molecular Biology (Promoter Gene Sequences) Data Set Below are papers that cite this data set, with context ... Return to Molecular Biology (Promoter Gene Sequences) data set page. Ken Tang and Ponnuthurai N. Suganthan and Xi Yao and A. ... of real credit card transactions and two molecular biology sequence analysis data sets, were used in our experiments. The ... The six data sets are landsat, optdigits, vehicle, DNA thyroid disease and vowel data sets. Landsat. The Landsat data set is ...http://archive.ics.uci.edu/ml/support/Molecular+Biology+
Historical male-mediated introgression in horseshoe bats revealed by multilocus DNA sequence data - MAO - 2010 - Molecular...
Molecular EcologyVolume 19, Issue 7, Version of Record online: 8 MAR 2010. ...http://onlinelibrary.wiley.com/doi/10.1111/j.1365-294X.2010.04560.x/pdf
Eurosurveillance | S-OtrH3N2 viruses: use of sequence data for description of the molecular characteristics of the viruses and...
With the help of data generated from the World Health Organization Collaborating Centre for Reference and Research on Influenza ... S-OtrH3N2 viruses: use of sequence data for description of the molecular characteristics of the viruses and their relatedness ... S-OtrH3N2 viruses: use of sequence data for description of the molecular characteristics of the viruses and their relatedness ... 4 Institut Pasteur, Unit of Molecular Genetics of RNA Viruses, Department of Virology, Paris France 5 French National Centre ...http://www.eurosurveillance.org/content/10.2807/ese.16.50.20039-en
Abstract 5592: Molecular classification of triple negative breast cancer via RNA-sequencing data | Cancer Research
Abstract 5592: Molecular classification of triple negative breast cancer via RNA-sequencing data. Kevin J. Thompson, Xiaojia ... Molecular classification of triple negative breast cancer via RNA-sequencing data. [abstract]. In: Proceedings of the 105th ... Abstract 5592: Molecular classification of triple negative breast cancer via RNA-sequencing data ... Abstract 5592: Molecular classification of triple negative breast cancer via RNA-sequencing data ...http://cancerres.aacrjournals.org/content/74/19_Supplement/5592
Rhabdomyosarcoma | Cancer Genetics Web
... and whole-transcriptome sequencing methodology for a more definitive molecular classification. A total of 26 SRMS and ScRMS ... In conjunction with data from COG intermediate-risk treatment protocol D9803, our data demonstrate excellent outcomes for ... CONCLUSIONS: Our data demonstrate that CDK4 is necessary but overexpression is not sufficient for RB-E2F-mediated G1-phase cell ... Molecular Cytogenetics Detect an Unbalanced t(2;13)(q36;q14) and PAX3-FOXO1 Fusion in Rhabdomyosarcoma With Mixed Embryonal/ ...http://www.cancerindex.org/geneweb/X2002.htm
mua-3, a gene required for mechanical tissue integrity in Caenorhabditis elegans, encodes a novel transmembrane protein of...
Molecular Sequence Data. Muscles / metabolism. Organ Specificity. Protein Structure, Tertiary / physiology. Sequence Analysis, ... Washington University Genome Sequencing Center, C. briggsae sequence project). This sequence starts within the coding region of ... The Caenorhabditis elegans Sequencing Consortium. 1998. Genome sequence of the nematode C. elegans: a platform for ... Sequence comparison of classical and MUA-3 modules 47 50 64. factor IX:EC1. DGDQCES---NPCLNGGSCKDDINSYECWCPFGF----------EGKNCEL ...http://www.biomedsearch.com/nih/mua-3-gene-required-mechanical/11470828.html
Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses.
Molecular Sequence Data. Neisseria gonorrhoeae / immunology*. Phenotype. T-Lymphocytes, Helper-Inducer / immunology*. ... Carbohydrate Sequence. Cells, Cultured. Cricetinae. Cricetulus. Dendritic Cells / immunology*. Female. Glycosylation. Humans. ... Analyzed the data: SJvV. Contributed reagents/materials/analysis tools: LS JAAB JPMvP. Wrote the paper: SJvV JPMvP YvK.. ... Our data indicates that the terminal GalNAc residue, as found on LOS of GC phenotype C, skews T helper differentiation towards ...http://www.biomedsearch.com/nih/Variation-Neisseria-gonorrhoeae-lipooligosaccharide-directs/19834553.html
Differential expression of two flavonoid 3'-hydroxylase cDNAs involved in biosynthesis of anthocyanin pigments and 3...
Molecular Sequence Data. Molecular Structure. Sorghum / genetics*. Terpenes / chemistry, metabolism. Chemical. Reg. No./ ... 15939169 - Population data on 14 str loci from population of serbia and montenegro (new and renewe.... 25472159 - 110 barley ... Amino Acid Sequence. Anthocyanins / biosynthesis, chemistry. Cytochrome P-450 Enzyme System / biosynthesis, genetics*. DNA, ...http://www.biomedsearch.com/nih/Differential-expression-two-flavonoid-3/16943219.html
TRB@ | Cancer Genetics Web
Base Sequence. *Molecular Sequence Data. *Reproducibility of Results. *NOTCH1. *T-Cell Leukemia ... the TCR beta chain sequence serves as a molecular tag for each T-cell clone. Using these sequence tags, we assess similarities ... These data show that ultra-deep TCR-sequencing technology can be applied directly to DNA extracted from unfractionated tumour ... Sequence analysis showed that the cleavage occurred in the cryptic recombination signal sequences (RSSs) present throughout ...http://www.cancerindex.org/geneweb/TRB.htm
RAG1 | Cancer Genetics Web
Molecular Sequence Data. *Adolescents. *Acute Lymphocytic Leukaemia. *Childhood Cancer. *Flow Cytometry. *T-Cell Leukemia ... exome sequencing, Sanger sequencing, and functional analysis.. RESULTS: The 14-year-old patient, who had liver granuloma, ... such as high-throughput genomic translocation sequencing (HTGTS) and translocation-capture sequencing, combined with large- ... sequence-specific DNA binding - T cell differentiation in thymus - ubiquitin-protein ligase activity - V(D)J recombination - ...http://www.cancerindex.org/geneweb/RAG1.htm
In vitro biosynthesis of glycosylphosphatidylinositol in Aspergillus fumigatus.
Molecular Sequence Data. Oligopeptides / chemistry. Phosphatidylinositols / biosynthesis, chemistry. Uridine Diphosphate N- ... Thus, these biochemical data are in agreement with a comparative genome analysis that shows that all but 3 of the 21 genes ... Carbohydrate Sequence. Coenzyme A / metabolism. Ethanolamines / metabolism. Ethylmaleimide / chemistry. Glycolipids / ...http://www.biomedsearch.com/nih/In-vitro-biosynthesis-glycosylphosphatidylinositol-in/15568819.html
Cloning and expression analysis of goldfish (Carassius auratus L.) prominin.
This report describes a prominin-like sequence and express ... Molecular Sequence Data. Peptides / chemistry, genetics*. RNA, ... Base Sequence. Blotting, Southern / veterinary. Cloning, Molecular*. DNA Primers / chemistry. DNA, Complementary / chemistry. ... This report describes a prominin-like sequence and expression analysis of the prominin in the goldfish. The predicted amino ... Amino Acid Sequence. Animals. Antigens, CD / biosynthesis*, chemistry, genetics*. ...http://www.biomedsearch.com/nih/Cloning-expression-analysis-goldfish-Carassius/17123832.html
FOXL2 gene | Cancer Genetics Web
Nucleic Acid Regulatory Sequences *Young Adult. *Cancer DNA. *Molecular Sequence Data. *Chromosome 3 ... Molecular studies showed a heterozygous FOXL2 402C > G mutation in the tumor by direct gene sequencing. In addition, DNA ... sequence-specific DNA binding - sequence-specific DNA binding transcription factor activity - transcription factor binding - ... regulation of sequence-specific DNA binding transcription factor activity - RNA polymerase II distal enhancer sequence-specific ...http://www.cancerindex.org/geneweb/FOXL2.htm
MYD88 | Cancer Genetics Web
... detailed pathological and molecular data are still lacking. In the present study, the clinicopathological features and survival ... Sanger sequencing can easily detect levels of BM infiltration above 15% by WM lymphoplasmacytic cells, while the allele- ... Defining these mutations also sheds light on the molecular pathogenesis of MLN, furthering development of molecular targeting ... These data provide direct evidence for a tumor-promoting role of monocytes and macrophages in human cancer and indicate IL-1-IL ...http://www.cancerindex.org/geneweb/MYD88.htm
Tissue and developmental specificity of a polysialo-ganglioside species in the amphibian Xenopus.
Molecular Sequence Data. Oleic Acid / analysis. Organ Specificity. Palmitic Acid / analysis. Species Specificity. Spinal Cord ... Carbohydrate Sequence. Chick Embryo. Embryo, Nonmammalian / chemistry. G(M1) Ganglioside / analysis. Gangliosides / chemistry, ...http://www.biomedsearch.com/nih/Tissue-developmental-specificity-polysialo-ganglioside/8969459.html
EXTL1 | Cancer Genetics Web
Cloning, Molecular. *Breast Cancer. *Expressed Sequence Tags. *Molecular Sequence Data. *Mutation. *Physical Chromosome Mapping ... Molecular analysis of the putative tumour-suppressor gene EXTL1 in neuroblastoma patients and cell lines.. Eur J Cancer. 2004; ... Graph generated 17 August 2015 using data from PubMed using criteria.. Literature Analysis. Mouse over the terms for more ... Data table showing topics related to specific cancers and associated disorders. Scope includes mutations and abnormal protein ...http://www.cancerindex.org/geneweb/EXTL1.htm
POU1F1 | Cancer Genetics Web
Molecular Sequence Data. *Prolactin. *Homeodomain Proteins. *Tumor Stem Cell Assay. *Transcription. *Adolescents ... sequence-specific DNA binding - sequence-specific DNA binding transcription factor activity - somatotropin secreting cell ... However, no data are available on the role of Pit-1 on breast PRL. To evaluate this role, several human breast cancer cell ... These data indicate that complete loss of Prkar1a/PRKAR1A is able to cause pituitary tumors in mice and men. The pattern of ...http://www.cancerindex.org/geneweb/POU1F1.htm
IRF7 | Cancer Genetics Web
Molecular Sequence Data. *Neoplasm Proteins. *Chromosome 11. *MicroRNAs. *Gene Expression Profiling. Tag cloud generated 09 ... Employing deep sequencing, we sequenced mRNA transcripts in CIK(IL-2) and CIK(IL-15). A total of 374 differentially expressed ... RNA polymerase II core promoter sequence-specific DNA binding - sequence-specific DNA binding transcription factor activity - ... Our data strengthens the idea that there is a protective role against tumor progression for CysLT(2)R and that it highlights ...http://www.cancerindex.org/geneweb/IRF7.htm
Role of rhinovirus C in apparently life-threatening events in infants, Spain.
Molecular Sequence Data. Nasopharynx / virology. Phylogeny. Picornaviridae Infections* / epidemiology, physiopathology, ... Sequence from patient SO4923 had a low sequence similarity with the other serotypes of HRV-A. In contrast, sequences from ... Phylogenetic analyses of 9 sequences obtained from patients showed distribution of HRV in 3 clusters. Three sequences were ... HRVs from positive samples were identified by sequencing and phylogenetic analysis of these sequences. Amplified products ( ...http://www.biomedsearch.com/nih/Role-rhinovirus-C-in-apparently/19788827.html
Synthesis of carbohydrate derivatives using solid-phase work-up and scavenging techniques.
Molecular Sequence Data. Oligosaccharides / chemical synthesis*, chemistry. Tosyl Compounds / chemistry. Chemical. Reg. No./ ... Carbohydrate Sequence. Combinatorial Chemistry Techniques / methods*. Glycosides / chemistry. Glycosylation. Iodine / chemistry ...http://www.biomedsearch.com/nih/Synthesis-carbohydrate-derivatives-using-solid/12945889.html
The levels of ubiquitinated histone H2A are highly upregulated in transformed human cells: partial colocalization of uH2A...
Molecular Sequence Data. Proliferating Cell Nuclear Antigen / metabolism*. S Phase. Ubiquitins / genetics, immunology, ... Amino Acid Sequence. Antibodies, Monoclonal. Antigens / genetics. Cell Line. Cell Line, Transformed. Cell Transformation, ...http://www.biomedsearch.com/nih/levels-ubiquitinated-histone-H2A-are/7622605.html