Most recent papers with the keyword Ki 67 | Read by QxMD
... molecular and genetic characteristics of Burkitt-like lymphoma with chromosome 11q aberration. Methods: A case of Burkitt-like ... Clinicopathologic characteristics of Burkitt-like lymphoma with chromosome 11q aberration].. P Wei, Y L Zhang, J L Xie, Y Y ... status and molecular genetic characteristics. Results: The patient was a 38-year-old man presenting with the cervical ... clinicopathologic-characteristics-of-burkitt-like-lymphoma-with-chromosome-11q-aberration ...https://www.readbyqxmd.com/keyword/99999
Bepler G, Gautam A, McIntyre LM, et al Prognostic significance of molecular genetic aberrations on chromosome segment 11p15.5 ... Cells were lysed in 0.02 m Tris-HCl (pH 7.2) + protease inhibitor mixture (Roche Molecular Biochemicals) by freeze-thawing ... Probe arrays were stained serially with 10 mg/ml streptavidin-conjugated R-phycoerythrin (Molecular Probes, Eugene, OR) and 3 ... Lewis WH, Srinivasan PR Chromosome-mediated gene transfer of hydroxyurea resistance and amplification of ribonucleotide ...http://cancerres.aacrjournals.org/content/64/11/3761
Felix Mitelman - Wikipedia
The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer also contains information on the molecular genetic ... See below.) Mitelman F: Catalog of Chromosome Aberrations in Cancer, Karger, Basel 1983, ISBN 3-8055-3813-8; 2nd Ed. Alan R. ... Together with Fredrik Mertens and Bertil Johansson he maintains a database of all published chromosome aberrations in ... "Mitelman Database of Chromosome Aberrations in Cancer". Cancer Genome Anatomy Project. Retrieved 2008-03-01. ...https://en.wikipedia.org/wiki/Felix_Mitelman
Most recent papers with the keyword Fluorescence in-situ hybridization | Read by QxMD
... molecular and genetic characteristics of Burkitt-like lymphoma with chromosome 11q aberration. Methods: A case of Burkitt-like ... Despite advances in molecular genetic characterization of pediatric and adult tumors, the diagnosis of OS still depends almost ... Clinicopathologic characteristics of Burkitt-like lymphoma with chromosome 11q aberration].. P Wei, Y L Zhang, J L Xie, Y Y ... The lack of consistent genetic changes in OS has greatly hindered the development of any diagnostic molecular test. Recently, ...https://www.readbyqxmd.com/keyword/100680
Genetic Polymorphisms Associated with Environmental Exposure to Polycyclic Derivatives in African Children
L. Zhang, N. Rothman, G. Li et al., "Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in ... Molecular Analysis. DNA extraction was performed in peripheral blood leukocytes using DNA Kit 250 FlexiGene Qiagen (Hilden, ... Genetic Polymorphisms Associated with Environmental Exposure to Polycyclic Derivatives in African Children. Rodrigo Mota de ... X. Guo, Y. Zeng, H. Deng et al., "Genetic polymorphisms of CYP2E1, GSTP1, NQO1 and MPO and the risk of nasopharyngeal carcinoma ...https://www.hindawi.com/journals/dm/2018/9078939/
Rhode Island Mesothelioma Information | Surviving Mesothelioma
Pleural Cavity Chromosome Aberration, Disease Model, Environment Related Neoplasm /cancer, Genetic Marker, Model Design / ... First, molecular markers for chromosomal damage induced by asbestos fibers will be developed using biotinylated DNA probes and ... Genetic Disorders, Chromosome Abnormalities, Genetics, Cytogenetics, Haloalkylamines, Bcnu, Haloalkylamines, Cyclophosphamide, ... Kelsey, Karl T. The Epidemiology Of Molecular Alterations In Mesothelioma. Grant: 1R01CA126939-01A1 ...https://survivingmesothelioma.com/mesothelioma-locations/mesothelioma-united-states/rhode-island/
Complex cytogenetic abnormalities in a patient with chronic myeloid leukemia: a case report - Semantic Scholar
Cytogenetic and molecular genetic studies revealed the presence of a t(9; 22)(q34; q11) translocation and some additional ... A case of multiple chromosome aberrations in a patient with CML (chronic myeloid leukemia) in the accelerated phase was ... A case of multiple chromosome aberrations in a patient with CML (chronic myeloid leukemia) in the accelerated phase was ... Cytogenetic and molecular genetic evolution of chronic myeloid leukemia.. *Bertil Johansson, Thoas Fioretos, Felix Mitelman ...https://www.semanticscholar.org/paper/Complex-cytogenetic-abnormalities-in-a-patient-with-Lukyanova-Pie%C5%84kowska-Grela/58bdbe5c3f6c782a7e132cdc3fd5906a63aabbba
A Phase 1/2 Study of Ponatinib in Japanese Patients With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia ...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Ponatinib. Antineoplastic Agents. Protein Kinase ... Molecular responses [ Time Frame: Until the end of treatment, which may be up to 60 months ]. Major molecular response (MMR) ... Other measures include mutation testing and molecular genetic assessment. Accrual is expected to take approximately 12 months, ... Genetic and Rare Diseases Information Center resources: Acute Lymphoblastic Leukemia Myeloid Leukemia Chronic Myeloid Leukemia ...https://clinicaltrials.gov/ct2/show/NCT01667133
Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive ...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Imatinib Mesylate. Antineoplastic Agents. Protein Kinase ... Percent of patients achieving major molecular response at baseline and at last visit. ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ... Philadelphia Chromosome. Neoplasms by Histologic Type. Neoplasms. Myeloproliferative Disorders. Bone Marrow Diseases. ...https://clinicaltrials.gov/show/NCT00171899
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Imatinib Mesylate. Antineoplastic Agents. Protein Kinase ... Molecular Response Rate (MMR) at 12 Months [ Time Frame: Baseline, 12 months ]. Rate of MMR is defined as ,= 0.1% BCR-ABL/ABL ... Initial molecular response at 3 months may predict both response and event-free survival at 24 months in imatinib-resistant or ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ...https://clinicaltrials.gov/show/NCT00471497
Treatment Strategies for Children With Smith-Magenis Syndrome - Full Text View - ClinicalTrials.gov
Chromosome Disorders. Genetic Diseases, Inborn. Dyssomnias. Occupational Diseases. Monosomy. Aneuploidy. Chromosome Aberrations ... Failure to confirm clinical diagnosis of SMS by standard molecular cytogenetic (FISH) methods and/or DNA-based mutation ... Genetic and Rare Diseases Information Center resources: Chromosome 17p Deletion Smith-Magenis Syndrome ... Developmental Delay Disorders Chromosome Deletion Mental Retardation Sleep Disorders, Circadian Rhythm Self Injurious Behavior ...https://clinicaltrials.gov/ct2/show/NCT00506259?recr=Open&cond=%22Mental+Retardation%22&rank=12
Zytogenetische Grundlagen der molekularen Medizin | Springer for Research & Development
Migeon BR (1994) X-chromosome inactivation: molecular mechanisms and genetic consequences. Trends Genet 10: 230-235PubMed ... Mitelman F, Johansson B, Mertens F (1994) Catalog of chromosome aberrations in cancer, 5th edn. Wiley-Liss, New YorkGoogle ... Lee JT, Jaenisch R (1997) The (epi)genetic control of mammalian X-chromosome inactivation. Curr Opin Genet Dev 7: 274-280PubMed ... Kai R, Ohtsubo M, Sekiguchi M, Nishimoto T (1986) Molecular cloning of a human gene that regulates chromosome condensation and ...https://rd.springer.com/chapter/10.1007/978-3-662-07588-3_2
Single stem cell gene therapy for genetic skin disease | EMBO Molecular Medicine
... other mutations or chromosome aberrations that were already present in the skin of the patients or induced by the culture ... as genetic insertion in every stem cell cannot be precisely defined. In this issue of EMBO Molecular Medicine, Droz‐Georget ... Single stem cell gene therapy for genetic skin disease. Jean‐Christophe Larsimont, Cédric Blanpain ... In this issue of EMBO Molecular Medicine, Droz‐Georget Lathion et al developed a strategy that embraces international standards ...http://embomolmed.embopress.org/content/7/4/366
Gene expression identifies heterogeneity of metastatic behavior among high-grade non-translocation associated soft tissue...
Mitelman F: Recurrent chromosome aberrations in cancer. Mutat Res. 2000, 462 (2-3): 247-253.View ArticlePubMedGoogle Scholar. ... Ladanyi M, Bridge JA: Contribution of molecular genetic data to the classification of sarcomas. Hum Pathol. 2000, 31 (5): 532- ... Genes Chromosomes Cancer. 2009, 48 (11): 943-952.View ArticlePubMedGoogle Scholar. ... Huang J, Zheng DL, Qin FS, Cheng N, Chen H, Wan BB, Wang YP, Xiao HS, Han ZG: Genetic and epigenetic silencing of SCARA5 may ...https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-12-176
Molecular Biology of Chronic Myeloid Leukemia | SpringerLink
... is a clonal myeloproliferative disorder resulting from an acquired genetic aberration t(9;22)(q34;q11) (Philadelphia chromosome ... is a clonal myeloproliferative disorder resulting from an acquired genetic aberration t(9;22)(q34;q11) (Philadelphia chromosome ... Trisomy of chromosome 8, 19, isochromosome 17, and an additional Ph chromosome are the most frequent additional chromosomal ... Melo JV (1996a) The molecular biology of chronic myeloid leukemia. Leukemia 10:751-756PubMedGoogle Scholar ...https://link.springer.com/chapter/10.1007/978-3-642-29467-9_6
Ya-Huei Kuo, Ph.D., Associate professor | City of Hope
Using a genetic mouse model of a common chromosome aberration found in AML patients, known as inv(16), we have shown that ... We use defined genetic mouse models as an experimental system to identify molecular pathways and targets, and primary cells ... Molecular Genetics of Hematopoietic Stem Cells and Leukemia Stem Cells. Acute myeloid leukemia (AML) is the most common type of ... Our long-term goal is to elucidate the molecular mechanism(s) regulating the maintenance of LSCs, to understand how they differ ...https://www.cityofhope.org/chinese/people/kuo-ya-huei
Bone: Dedifferentiated chondrosarcoma
Molecular, genetic and epigenetic studies show that both tumor components share some genetic alterations; two clones derive ... Structural and numerical aberrations are most frequently reported for chromosomes 1 and 9. The non-uniform karyotype is ... Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its ... a part of the chromosome commonly demonstrated a repeated numerical aberration of +7, +8, +20, and +21. In addition, this cell ...http://atlasgeneticsoncology.org/Tumors/DediffChondrosarcID5337.html
Department of Bioscience and Laboratory Medicine｜HIROSAKI UNIVERSITY School of Health Sciences and Graduate School of Health...
Development of chemicals for radiation protection with chromosome aberration as a biological indicator. ○Roles of chromosome ... Molecular cytogenetic and genetic analyses of radiation-induced malignant tumors. ○ ... Radiation sensitivity in the general human population using chromosome aberration. ○Development and improvement of cytogenetic ... Molecular markers of blood coagulation factors and platelets in patients with thrombotic tendency Mitsuaki Yoshida, Professor ...http://www.hs.hirosaki-u.ac.jp/kouhou/hg/en/daigakuin/course_list03.html
Professor Shareen Doak
Doak, S. (2003). Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett's oesophagus. Gut 52(5 ... Experimental and Molecular Pathology 95(2), 220-226.. https://cronfa.swan.ac.uk/Record/cronfa16741 doi:10.1016/j.yexmp.2013.07. ... BAYLIS, R. DOAK, S. PARRY, J. & DUNSTAN, P. (2006). Chromosome morphology after long-term storage investigated by scanning near ... Wills JW, Johnson GE, Doak SH, Soeteman-Hernández LG, Slob W, White PA (2015). Empirical analysis of BMD metrics in genetic ...http://www.swansea.ac.uk/staff/medicine/learningandteaching/doaksh/name,164193,en.php
Fished out | definition of fished out by Medical dictionary
Called also chromosome painting.. molecular hybridization in molecular biology, formation of a partially or wholly ... a genetic mapping technique using fluorescent tags for analysis of chromosomal aberrations and genetic abnormalities. ... Molecular medicine Fluorescent In Situ Hybridization. A method for locating a segment of DNA on a chromosome. The DNA is ... where probes for particular chromosomes-e.g., chromosomes 13, 18, 21-or chromosomal regions-e.g., ABL and BCR genes in the ...http://medical-dictionary.thefreedictionary.com/fished+out
Cytogenetics - Technologies, Markets and Compan... ( DUBLIN August 1 2013 /- Resea...)
Microarray/biochip-based technologies for cytogenetics promise to speed up detection of chromosome aberrations now examined by ... 5. Molecular Imaging & Single Molecular Detection. 6. Role of Nanobiotechnology in Cytogenetics. 7. Biomarkers and Cytogenetics ... which account for a significantly greater proportion of genetic variation between closely-related genomes as compared to single ... In the age of molecular biology, it is also referred to as molecular cytogenetics. Historical landmarks in the evolution of ...http://www.bio-medicine.org/biology-technology-1/Cytogenetics---Technologies--Markets-and-Companies---2013-27133-1/
Gene Disease Database - Wikipedia
Genetic illnesses are caused by aberrations in genes or chromosomes. Many genetic diseases are developed from before birth. ... Trends in Molecular Medicine (2014) doi:10.1016/j.molmed.2014.10.002 Control of VEGF-A transcriptional programs by pausing and ... The Genetic Association Database is an archive of human genetic association studies of complex diseases. GAD is primarily ... This information enables the genetic counselor to predict the risk for occurrence of a large number of genetic disorders. Most ...https://en.wikipedia.org/wiki/Gene_Disease_Database
How cells handle broken chromosomes
Molecular Cell 33, February 13th, 2009). The central molecule for life is DNA, which constitutes the genetic blueprint of our ... A single DSB is enough to kill a cell or cause chromosomal aberrations leading to cancer. ... Molecular Cell , Molecular Target , RAD51 , cancer development , cell death , chip-on-chip technique , chromosomes , ... Molecular Target »RAD51 »cancer development »cell death »chip-on-chip technique »chromosomes »degenerative diseases » ...http://www.innovations-report.com/html/reports/life-sciences/cells-handle-broken-chromosomes-127292.html
Jeffrey L. Sklar, MD, PhD > Laboratory Medicine: Education & Training | Laboratory Medicine | Yale School of...
... chromosome structure and chromosomal aberrations in human disease; trans-splicing of RNA; genetic predisposition to type 2 ... Clinical interests: Molecular diagnostics.. Research Interests: Molecular biology of human disease, especially cancer; gene ... Pathology: Autopsy , Experimental Pathology Graduate Program , Molecular & Genomic Pathology , Pathology Research , Sklar Lab ... Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology: Cancer ...http://labmed.yale.edu/training/fellowships/hematopathology/jeffrey_sklar.profile
The DrosDel collection : a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster.
Animals, Chromosome Aberrations, DNA Transposable Elements/*genetics, Drosophila melanogaster/*genetics, Genetic Techniques, ... Molecular Biology (Faculty of Science and Technology) Search outside of DiVA. GoogleGoogle Scholar. ... In addition, a further 37,000 deletions, selectable by molecular screening, may be generated. We are now using the collection ... The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. ...http://umu.diva-portal.org/smash/record.jsf?pid=diva2:156500