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*  Carnitine palmitoyltransferase II - Wikipedia
... is a mitochondrial membrane protein which is transported to the mitochondrial inner membrane. CPT2 together with carnitine ... Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders and carnitine ... Carnitine O-palmitoyltransferase 2, mitochondrial is an enzyme that in humans is encoded by the CPT2 gene. Carnitine ... Britton CH, Schultz RA, Zhang B, Esser V, Foster DW, McGarry JD (1995). "Human liver mitochondrial carnitine ...
  https://en.wikipedia.org/wiki/Carnitine_palmitoyltransferase_II
*  Medical Home Portal - CACT Deficiency
CACT is a mitochondrial membrane carrier protein, responsible for transport of long-chain fatty acids conjugated with carnitine ... Without CACT, long-chain acylcarnitines cannot enter mitochondrial to undergo subsequent oxidation, production of ATP, and ... Long-chain acylcarnitines and free fatty acids can alter the electrical properties of cardiac cells resulting in arrhythmia. ... Support initiation and maintenance of dietary restriction of long chain fatty acids, high carbohydrate/low-fat diet, avoidance ...
  https://www.medicalhomeportal.org/newborn/cact-deficiency
*  anti-CPT2 antibody [N1C1] | GeneTex
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with ... the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial ... long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq]. Synonyms. CPT1 antibody, CPTASE antibody, CPT2 antibody ... Recombinant protein encompassing a sequence within the center region of human CPT2. The exact sequence is proprietary. ...
  http://www.genetex.com/CPT2-antibody-N1C1-GTX104115.html
*  CPT2 polyclonal antibody - (PAB4374) - Products - Abnova
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with ... the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial ... Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and ... Store at 4°C. For long term storage store at -20°C.. Aliquot to avoid repeated freezing and thawing. ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=PAB4374
*  Beta oxidation - Wikipedia
Free fatty acids must cross the cell membrane through specific transport proteins, such as the SLC27 family fatty acid ... If the fatty acyl-CoA contains a short chain, these short-chain fatty acids can simply diffuse through the inner mitochondrial ... A long-chain fatty acid is dehydrogenated to create a trans double bond between C2 and C3. This is catalyzed by acyl CoA ... Long-chain-fatty-acid-CoA ligase catalyzes the reaction between a fatty acid with ATP to give a fatty acyl adenylate, plus ...
  https://en.wikipedia.org/wiki/Beta_oxidation
*  Meldonium - Wikipedia
In fatty acid (FA) metabolism, long chain fatty acids in the cytosol cannot cross the mitochondrial membrane because they are ... This complex is then transported through the inner mitochondrial membrane via a transporter protein called carnitine- ... Carnitine transports activate long-chain fatty acids (FA) from the cytosol of the cell into the mitochondrion and is therefore ... Long chain FA are first activated via esterification with coenzyme A to produce a fatty acid-coA complex which can then cross ...
  https://en.wikipedia.org/wiki/Meldonium
*  Plant Cell Membranes: Volume 148 : Nathan P. Colowick : 9780121820480
Plant Cell Membranes: Volume 148 by Nathan P. Colowick, 9780121820480, available at Book Depository with free delivery ... Polar Lipids of Chloroplast Membranes.. Isolation and Reconstitution of Thylakoid Lipids.. Long-Chain Fatty Acid Synthesis and ... Cell-Free Reconstitution of Protein Transport into Chloroplasts.. ... Phosphoglycerides of Mitochondrial Membranes.. Ubiquinone Biosynthesis in Plant Mitochondria.. Purification of Complexes II and ...
  https://www.bookdepository.com/Plant-Cell-Membranes-Nathan-P-Colowick/9780121820480
*  ACSL3 | Cancer Genetics Web
long-chain fatty acid-CoA ligase activity - long-chain fatty-acyl-CoA biosynthetic process - mitochondrial outer membrane - ... peroxisomal membrane - positive regulation of Golgi to plasma membrane protein transport - positive regulation of ... We found previously that long-chain fatty-acid-CoA ligase 3 (FACL3), a critical enzyme for activation of long-chain fatty acids ... The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in ...
  http://www.cancerindex.org/geneweb/ACSL3.htm
*  NBE-Research
... a serum protein produced by the liver. Several proteins have been identified that facilitate transport of long chain fatty ... But enzymes specific for very long chain fatty acids are associated with the inner mitochondrial membrane, facing the matrix.. ... including the plasma membrane protein CD36.. Fatty acids are degraded in the mitochondrial matrix via the b-Oxidation Pathway. ... It contains various transport catalysts, including a carrier protein that allows pyruvate to enter the matrix. It is highly ...
  http://breastnexus.com/showthread.php?tid=23246
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... In principle, the assay is not limited to K+-transporting membrane proteins, but it may work equally well to address the ... BCL-2 family proteins such as Bax enter the mitochondrial outer membrane, oligomerize and permeabilize the outer membrane, ... Membrane Proteins, Micelles, Molecular Motor Proteins, life sciences, biochemistry, Amino Acids, Peptides, and Proteins, lipid- ...
  https://www.jove.com/visualize/abstract/23626747/penetrating-cations-enhance-uncoupling-activity-anionic-protonophores
*  NDUFB4 - Wikipedia
... which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. ... The NDUFB4 gene, located on the q arm of chromosome 3 in position 13.33, is 6,130 base pairs long. The NDUFB4 protein weighs 15 ... It locates at the mitochondrial inner membrane. This protein complex has NADH dehydrogenase activity and oxidoreductase ... complex at the inner mitochondrial membrane. The human NDUFB4 gene codes for a subunit of Complex I of the respiratory chain, ...
  https://en.wikipedia.org/wiki/NDUFB4
*  NDUFB5 - Wikipedia
... which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. ... The NDUFB5 gene, located on the q arm of chromosome 3 in position 26.33, is 19,713 base pairs long. The NDUFB5 protein weighs ... complex at the inner mitochondrial membrane. The human NDUFB5 gene codes for a subunit of Complex I of the respiratory chain, ... the N-terminal hydrophobic domain has the potential to be folded into an alpha helix spanning the inner mitochondrial membrane ...
  https://en.wikipedia.org/wiki/NDUFB5
*  NDUFA4L2 - Wikipedia
... which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. ... The NDUFA4L2 gene is located on the long q arm of chromosome 12 at position 13.3 and it spans 5,860 base pairs. NDUFA4L2 is a ... NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 is a protein that in humans is encoded by the NDUFA4L2 gene. The ... complex at the inner mitochondrial membrane. The human NDUFA4L2 gene codes for a subunit of Complex I of the respiratory chain ...
  https://en.wikipedia.org/wiki/NDUFA4L2
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... In principle, the assay is not limited to K+-transporting membrane proteins, but it may work equally well to address the ... Membrane protein folding is an emerging topic with both fundamental and health-related significance. The abundance of membrane ... The mitochondrial permeability transition pore (mtPTP) is a non specific channel that forms in the inner mitochondrial membrane ...
  https://www.jove.com/visualize/abstract/21887290/rectification-of-the-water-permeability-in-cos-7-cells-at-22-10-and-0c
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... protein kinase C, renal proximal tubular cells, reactive oxygen species, oxygen consumption, electron transport chain, ... The mitochondrial permeability transition pore (mtPTP) is a non specific channel that forms in the inner mitochondrial membrane ... The dyes employed for Ca2+ measurement in the assay medium and mitochondrial membrane potential are Fura FF, a membrane ...
  https://www.jove.com/visualize/abstract/22479585/bak-compensated-for-bax-p53-null-cells-to-release-cytochrome-c-for
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... transport of biomolecules, proteomic studies and analysis of mitochondrial DNA, proteins and lipids. ... BCL-2 family proteins such as Bax enter the mitochondrial outer membrane, oligomerize and permeabilize the outer membrane, ... The mitochondrial permeability transition pore (mtPTP) is a non specific channel that forms in the inner mitochondrial membrane ...
  https://www.jove.com/visualize/abstract/22701687/phylogenetic-analysis-complete-mitochondrial-genome-madurella
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... protein kinase C, renal proximal tubular cells, reactive oxygen species, oxygen consumption, electron transport chain, ... BCL-2 family proteins such as Bax enter the mitochondrial outer membrane, oligomerize and permeabilize the outer membrane, ... Mitochondrial membrane potential (ΔΨm) is critical for maintaining the physiological function of the respiratory chain to ...
  https://www.jove.com/visualize/abstract/20548781/polymorphisms-mitochondrial-dna-control-region-frailty-older
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... protein kinase C, renal proximal tubular cells, reactive oxygen species, oxygen consumption, electron transport chain, ... Mitochondrial membrane potential (ΔΨm) is critical for maintaining the physiological function of the respiratory chain to ... The mitochondrial permeability transition pore (mtPTP) is a non specific channel that forms in the inner mitochondrial membrane ...
  https://www.jove.com/visualize/abstract/24303051/early-deficits-glycolysis-are-specific-to-striatal-neurons-from-rat
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... protein kinase C, renal proximal tubular cells, reactive oxygen species, oxygen consumption, electron transport chain, ... Mitochondrial membrane potential (ΔΨm) is critical for maintaining the physiological function of the respiratory chain to ... Methods to detect and monitor mitochondrial outer membrane protein components in animal tissues are vital to study ...
  https://www.jove.com/visualize/abstract/23326576/monomer-dj-1-its-n-terminal-sequence-are-necessary-for-mitochondrial
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... protein kinase C, renal proximal tubular cells, reactive oxygen species, oxygen consumption, electron transport chain, ... Methods to detect and monitor mitochondrial outer membrane protein components in animal tissues are vital to study ... The mitochondrial permeability transition pore (mtPTP) is a non specific channel that forms in the inner mitochondrial membrane ...
  https://www.jove.com/visualize/abstract/19557129/linoleic-acid-induced-mitochondrial-ca-2-efflux-causes-peroxynitrite
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... BCL-2 family proteins such as Bax enter the mitochondrial outer membrane, oligomerize and permeabilize the outer membrane, ... is a non specific channel that forms in the inner mitochondrial membrane to transport solutes with a molecular mass smaller ... Mitochondrial membrane potential (ΔΨm) is critical for maintaining the physiological function of the respiratory chain to ...
  https://www.jove.com/visualize/abstract/23520503/metabolic-adaptation-to-chronic-inhibition-mitochondrial-protein
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... protein kinase C, renal proximal tubular cells, reactive oxygen species, oxygen consumption, electron transport chain, ... pre-synaptic vesicle transport, dendritic transport of glutamate receptors, mitochondrial transport, synaptotagmin transport, ... BCL-2 family proteins such as Bax enter the mitochondrial outer membrane, oligomerize and permeabilize the outer membrane, ...
  https://www.jove.com/visualize/abstract/21179577/amyloid-triggers-release-neuronal-hexokinase-1-from
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... mitochondrial membrane depolarization or uncoupling, and long chain fatty acids4. In vitro, mtPTP opening can be achieved by ... transport of biomolecules, proteomic studies and analysis of mitochondrial DNA, proteins and lipids. ... of protein-protein interactions. Briefly, the integral membrane bait protein is fused to Cub which is linked to an artificial ... The mitochondrial permeability transition pore (mtPTP) is a non specific channel that forms in the inner mitochondrial membrane ...
  https://www.jove.com/visualize/abstract/22563492/alternative-splicing-spg7-gene-involved-hereditary-spastic-paraplegia
*  Molecular evolution - Wikipedia
Mitochondrial and chloroplast DNA varies across taxa, but membrane-bound proteins, especially electron transport chain ... Genes with longer introns are more likely to recombine due to increased physical distance over the coding sequence. As such, ... these proteins are called as homologous proteins. More specifically, homologous proteins that exist in two distinct species are ... What they found was that the rates were not the same among proteins. Each protein has its own rate, and that rate is constant ...
  https://en.wikipedia.org/wiki/Molecular_evolution
*  The Role of the Transcription Factor Foxo3 in Hearing Maintenance: Informed Speculation on a New Player in the Cochlea
... are no longer able to maintain the membrane voltage difference that is the hallmark of the active electron transport chain. ... α coordinates new production of mitochondrial proteins from both the nucleus and mitochondrial DNA (mtDNA) [56]. In conjunction ... R. Martins, G. J. Lithgow, and W. Link, "Long live FOXO: unraveling the role of FOXO proteins in aging and longevity," Aging ... When the cochlear mitochondrial respiratory chain is inhibited with 3-nitropropionic acid applied to the round window, ...
  https://www.hindawi.com/journals/bmri/2016/1870675/