*  Microtubule Orientation in the Brassinosteroid Mutants lk, lka and lkb of Pea - Open Access Repository
Knowles, CL and Koutoulis, A and Reid, JB (2004) Microtubule Orientation in the Brassinosteroid Mutants lk, lka and lkb of Pea. ... the microtubules (MTs). This study adds to our. knowledge the fact that brassinolide (BL) can cause. MT realignment in azuki ... Microtubule Orientation in the Brassinosteroid Mutants lk, lka and lkb of Pea ...
  https://eprints.utas.edu.au/12566/
*  Microtubule Self-Assembly Kinetics - Durham University
Microtubule assembly and disassembly is vital for many fundamental cellular processes. Our current understanding of microtubule ... This is because there is a shift in microtubule tip structure from relatively blunt at low free concentrations to relatively ... Together, our studies lead to a major revision of kinetic estimates of microtubule assembly, and provide a new perspective on ... Biomathematics Seminar: Microtubule Self-Assembly Kinetics. Presented by Davide Odde, University of Minnesota ...
  https://www.dur.ac.uk/mathematical.sciences/events/seminars/seminararchives/?seminar=3361
*  Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1 |...
Effects of siRNA-induced CAPN6 knockdown on the association of GEF-H1 with microtubules and active Rac1. (A,B) Microtubule co- ... 5A,B). In this assay, the total amount of microtubules sedimented (stabilized microtubules) was the same in control and Capn6- ... The initial polarization of microtubule assembly is led by actin filaments, and conversely the polarized microtubules ... we have demonstrated that CAPN6 can bind to microtubules, mainly through domain III, and induce microtubule stabilization ...
  http://jcs.biologists.org/content/124/8/1214
*  CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content | JCB
... that bridge the transition zone microtubules with the membrane are missing from most cep290 doublet microtubules. Insets in C ... Microtubule-membrane interactions in Chlamydomonas flagella. In The Chlamydomonas Sourcebook. Volume 3. G.B. Witman, editor. ... Basal bodies and microtubules. J. Cell Biol. 38:403-425. doi:10.1083/jcb.38.2.403. ... I. Isolation and electrophoretic analysis of microtubules, matrix, membranes, and mastigonemes. J. Cell Biol. 54:507-539. doi: ...
  http://jcb.rupress.org/content/190/5/927
*  Cylindrical Cell Structure Parts May Aid in Targeting Diseases Such as Cancer, Alzheimer's, Parkinson's - Neuroscience News
The model of microtubule assembly that most people accept shows the individual subunits, dimers of the protein tubulin, just ... Image Source: Kinesin dimer on the microtubule image is adapted from a Wikimedia Commons image shared by user Kebes with the CC ... "If nature invokes the two interactions in which part of the microtubule is flattened, then it may show us the function and ... "We want to understand the structure and regulation of microtubules because they are not static; they are always moving as they ...
  http://neurosciencenews.com/microtubule-tubulin-lateral-interactions-computational-neuroscience/
*  Dynein and Mast/Orbit/CLASP have antagonistic roles in regulating kinetochore-microtubule plus-end dynamics | Journal of Cell...
... microtubules, cell cortex, centrosomes and microtubule plus-ends (Dujardin and Vallee, 2002; Hays et al., 1994; Pfarr et al., ... microtubule plus-end incorporation in the absence of both proteins (Mast and dynein) might be restored because microtubules are ... because plus-end microtubule polymerization was restored. To test this possibility, we analyzed the microtubule plus-end ... which does not contain the microtubule-binding domain) could be seen streaming poleward along spindle microtubules (Fig. 2B; ...
  http://jcs.biologists.org/content/122/14/2543
*  Nanoscale Force Generation and Rigidity of Isotypically Purified b-Tubulin Microtubules
Nanoscale Force Generation and Rigidity of Isotypically Purified β-Tubulin Microtubules. K Beinert and J A Tuszynski*. ... Microtubules are one of three cytoskeletal filaments found in eukaryotic cells, which exhibit a constant transition between ... We have investigated microtubule dynamics found in isotypically purified β-tubulin in order to understand how different ... The rate constants determined by our model were found to vary significantly between β-II, β-III, and β-IV microtubules. This ...
  http://www.foresight.org/Conferences/AdvNano2004/Abstracts/Beinert/index.html
*  Plant microtubules | Journal of Cell Science
Similarly, a homologue of the microtubule-severing protein katanin p60 also plays an essential role in cortical microtubule ... which form crossbridges between adjacent microtubules and maintain microtubule spacing. It is a relative of the Dis1/TOG/ ... Microtubules in animal cells at interphase generally form highly organized radial arrays anchored by centrosomes. Plant ... Highly similar MAPs thus appear able to coordinate remarkably different microtubule organization strategies. ...
  http://jcs.biologists.org/content/115/7/e702
*  Yeast microtubules run out of Amo | Journal of Cell Science
... suggest that the interplay between the nucleus and microtubules is important for the regulation of microtubule dynamics. ... Microtubules play a central role in cell division and cell polarity in eukaryotic cells. Fission yeast represents a useful ... The phenotype of amo1Δ cells indicates that Amo1 helps to regulate microtubule growth, cell-end termination and cell polarity. ... However, Pardo and Nurse find no evidence that the loading of factors affecting microtubule dynamics is defective in amo1Δ ...
  http://jcs.biologists.org/content/118/8/e802
*  Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells | JCB
We show that the steady-state microtubule network appears to form by a combination of microtubule-microtubule and microtubule- ... However, the addition of increased microtubule stabilization at microtubule-microtubule and microtubule-cortex interactions ... microtubule network is generated by increased microtubule stabilization at sites of microtubule-microtubule and microtubule- ... generated microtubule nucleation sites coupled with microtubule stabilization upon microtubule-microtubule and microtubule- ...
  http://jcb.rupress.org/content/171/5/845
*  MAPless microtubule dynamics | Journal of Cell Science
For example, the authors show that the persistent growth of microtubules does not require the activity of microtubule- ... Microtubules - polymers of tubulin - are important components of the cytoskeleton. They constantly cycle between periods of ... Overall, the authors' findings provide a foundation for a better understanding of microtubule dynamics. In addition, they ... associated proteins (MAPs) but is an inevitable consequence of a nucleated system of dynamic microtubules polymerizing in a ...
  http://jcs.biologists.org/content/119/22/e2204
*  MAP65 Coordinate Microtubule Growth during Bundle Formation
In cooperation with microtubule-associated proteins (MAPs), MTs form bundles endowing cells with specific mechanisms to control ... Microtubules (MTs) are highly dynamical structures that play a crucial role in cell physiology. ... Microtubules Is the Subject Area "Microtubules" applicable to this article? Yes. No. ... Microtubules (MTs) are highly dynamical structures that play a crucial role in cell physiology. In cooperation with microtubule ...
  http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056808
*  Colchicine effect on microtubules
Ligands; Microtubule-Associated Proteins/isolation & purification; Microtubule-Associated Proteins/metabolism; Microtubules/ ... Colchicine Inhibition of Microtubule. Pathogen via Copolymer. Formation*. (Possible for colchicine effect on microtubules, ... Main / Summer Savings / Colchicine effect on microtubules Mechanism of inhibition of microtubule polymerization by colchicine: ... Quantitation of the Antidepressant ofCD Complexon Microtubule. Infusion. Microtubule assembly at. Unlike cold or allergy sinus ...
  http://geptsite.info/summer-savings/colchicine-effect-on-microtubules.php
*  Microtubule plus-end binding protein EB1 is necessary for muscle cell differentiation, elongation and fusion | Journal of Cell...
The mutated EB1-GFP decorated microtubule plus-ends or the whole length of the microtubules depending on the expression level ( ... Considering that EB1 is the isoform necessary for microtubule stabilization in fibroblasts and that microtubule stabilization ... the staining appears to spread from the microtubule plus-ends to the total length of microtubules. We do not know whether this ... show the comet-like pattern and a finer punctate staining along microtubules (arrow). The microtubule plus-end EB1 comets are ...
  http://jcs.biologists.org/content/122/9/1401
*  Cell microtubules, anaglyph 3D - Stock Video Clip K003/4489 - Science Photo Library
This clip shows the microtubules of the cell's cytoskeleton, surrounded by proteins in the cytoplasm, with the motor protein ... Cell microtubules, anaglyph 3D animation. Clip 4 of 10. This clip forms part of an animation sequence showing protein ... microtubule, microtubules, modelled, molecular, molecule, molecules, motor protein, moving, nanoscale, protein, protein ... Caption: Cell microtubules, anaglyph 3D animation. Clip 4 of 10. This clip forms part of an animation sequence showing protein ...
  http://www.sciencephoto.com/media/477202/view
*  DSpace at IIT Bombay: Transcription factor NF-kappa B associates with microtubules and stimulates apoptosis in response to...
Using TN16, a known microtubule targeting agent, we found that microtubule dynamics plays a critical role in NF-kappa B- ... Transcription factor NF-kappa B associates with microtubules and stimulates apoptosis in response to suppression of microtubule ... microtubule interaction. Treatment of cells with low concentrations of TN16 (25 and 50 nM) that suppressed microtubule dynamics ... Here, we found that NF-kappa B is associated with polymeric tubulin and co-localized with microtubules in MCF-7 cells. ...
  http://dspace.library.iitb.ac.in/jspui/handle/100/17569
*  Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission | Journal of Cell Science
Finally, we show that central spindle microtubule reorganization is driven by localized microtubule buckling and breaking, ... Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission. John A. Schiel, Kristin Park, Mary ... Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission. John A. Schiel, Kristin Park, Mary ... Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission. John A. Schiel, Kristin Park, Mary ...
  http://jcs.biologists.org/content/early/2011/04/12/jcs.081448
*  NuMA-tic Motoring | Science
... a complex of the microtubule motor protein dynein and dynactin powers NuMA transport along microtubules to the polar region. ... During mitosis, two arrays of microtubules form the bipolar mitotic spindle in order to effect partitioning of the duplicated ... and a protein known as NuMA is needed to properly gather the ends of the microtubules at the poles. ... perhaps through binding of the individual microtubules to a NuMA multimer. Disruption of NuMA transport by addition of the ...
  http://science.sciencemag.org/content/288/5471/1551.2
*  Kinesin/myosin in microtubules
... x011 at Lehigh.EDU x011 at Lehigh.EDU Fri Mar 24 09:03:28 EST 1995 *Previous message: ... The data curve supports this with a ossilation of 50/50 hook up of the myosin/kinesin system to the microtubules. It is ... Gilbert et al reports that myosin and kinesin are binary switching in the microtubules. These dimer actions I naturally see as ... important to note that there is considerable interest in the microtubules because the dimers support quantum interactions and ...
  http://www.bio.net/bionet/mm/neur-sci/1995-March/017486.html
*  EXTRACELLULAR MICROTUBULES | JCB
The mastigoneme microtubule is of smaller diameter (170-190 A) than cytoplasmic microtubules in these or other plant cells. ...
  http://jcb.rupress.org/content/40/2/446
*  Thinning microtubules | JCB
The clusters carried with them centrosomal proteins such as γ-tubulin, the microtubule nucleator. The release of microtubules ... where microtubules were previously scarce. Because the freed microtubules are not protected at their minus ends, they are more ... Centrosomes spit out microtubules to thin out their load at the end of mitosis, as illustrated by Rusan and Wadsworth on page ... Microtubules were released and actively transported outwards in the direction of the cell poles (away from the chromosomes), ...
  http://jcb.rupress.org/content/168/1/9.2
*  Atomic View of Microtubules | Berkeley Lab
Berkeley Lab and UC Berkeley researchers have produced an atomic view of microtubules furthering the understanding of cell ... "Our study shows how EB proteins can either facilitate microtubule assembly by binding to sub-units of the microtubule, ... or else cause a microtubule to disassemble by promoting GTP hydrolysis that destabilizes the microtubule lattice," says Eva ... Atomic View of Microtubules. Berkeley Lab Researchers Achieve Record 3.5 Angstroms Resolution and Visualize Action of a Major ...
  https://newscenter.lbl.gov/2015/08/04/atomic-view-of-microtubules/
*  Dynamics of microtubules - LMU Munich
Dynamics of microtubules. München, 04/06/2018. Filamentous polymers called microtubules play vital roles in chromosome ... Microtubules not only confer mechanical stability on cells and help to dictate their form, they also serve as an intracellular ... The longer the microtubule, the greater the number of motor proteins it can accommodate. Motor molecules called kinesins ... Furthermore, microtubules are the major constituents of the mitotic spindle, which mediates the orderly segregation of the ...
  http://www.en.uni-muenchen.de/news/newsarchiv/2018/frey_mikrotubuli.html
*  Microtubules shape the cell | JCB
... consisting of a well-defined system of microtubules, Tilney and Porter reasoned that "if the microtubules are instrumental in ... Soon after microtubules were first described by electron microscopy, several investigators began suggesting that they were ... Disassembly of the microtubules with these treatments prevented the characteristic cell shape changes in, and thus ... Cold treatment of A. nucleofilum cells caused the microtubules to disassemble and the axopodia to withdraw; after returning the ...
  http://jcb.rupress.org/content/169/4/553.1