Characterization of the Discriminative Stimulus Effects of the Neuroactive Steroid Pregnanolone in DBA/2J and C57BL/6J Inbred...
Subjects. Twelve DBA/2J male mice, 13 DBA/2J female mice, 12 C57BL/6J male mice, and 12 C57BL/6J female mice were obtained from ... Pregnanolone. DBA/2J male mice (n = 12), DBA/2J female mice (n = 13), and C57BL/6J female mice (n = 12) acquired the ... Notably, in this study there were differences between male DBA/2J and C57BL/6J mice, where the male C57BL/6J mice displayed ... for the male mice and 24% for the female mice. The highest dose tested in the female C57BL/6J mice (1.7 mg/kg) only produced 32 ...http://jpet.aspetjournals.org/content/314/2/675
Individual differences in the antibody response of inbred C57Bl/6J mice and their relation to individual differences in open...
Mice of the inbred C57Bl/6J strain displayed high variability in the antibody response of the IgG class to heat-aggregated ... Individual differences in the antibody response of inbred C57Bl/6J mice and their relation to individual differences in open- ... Male and female mice of the C57Bl/6J strain were purchased from Harlan Iberica (Barcelona, Spain). Seven C57Bl/6J females were ... one goal of this report was to find out if such differences occurred in mice of the C57Bl/6J inbred strain. ...http://www.elsevier.es/es-revista-anuario-psicologia-the-ub-199-articulo-individual-differences-in-antibody-response-S0066512617300041
Acute exercise induces FGF21 expr... preview & related info | Mendeley
Mice. *Mice, Inbred C57BL. *PPAR alpha. *PPAR alpha: metabolism. *Physical Conditioning, Animal ... Here, we showed that serum FGF21 level is increased in mice after a single bout of acute exercise, and that this is accompanied ... FGF21 gene expression was induced in the liver but not in skeletal muscle and white adipose tissue of mice after acute exercise ... Acute exercise induces FGF21 expression in mice and in healthy humans.. *Kim K ...https://www.mendeley.com/research-papers/acute-exercise-induces-fgf21-expression-mice-healthy-humans/
Daniel O. Schmitt, Professor of Evolutionary Anthropology and Associate of the Duke Initiative for Science & Society
Mice • Mice, Inbred C57BL • Mice, Transgenic • Middle Aged • Mobility Limitation • Models, Biological • Monoamine Oxidase ... Inbred Lew • Rats, Sprague-Dawley • Receptors, Tumor Necrosis Factor, Type II • Reference Values • Regression Analysis • Risk ...https://fds.duke.edu/db/aas/BAA/faculty%2520all/daniel.schmitt
Expression and regulation of ST2, an interleukin-1 receptor family member, in cardiomyocytes and myocardial infarction.
Mice. Mice, Inbred C57BL. Myocardial Infarction / blood, metabolism*. Myocardium / cytology, metabolism*. Nuclease Protection ... In mice subjected to coronary artery ligation, serum ST2 was transiently increased compared with unoperated controls (20.8+/- ... 0/Angiotensin Receptor Antagonists; 0/Biological Markers; 0/CP 191166; 0/IL1RL1 protein, human; 0/Il1rl1 protein, mouse; 0/ ...http://www.biomedsearch.com/nih/Expression-regulation-ST2-interleukin-1/12460879.html
Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell...
Mice. Mice, Inbred C57BL. Mice, Inbred CBA. Neurons / cytology*, drug effects, physiology. Phenotype*. Pregnancy. ... We used microarray-based expression profiling to identify a set of markers expressed by mouse NS cells but not ES cells. One ...http://www.biomedsearch.com/nih/Fibroblast-growth-factor-induces-neural/18504136.html
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response.
Mice. Mice, Inbred C57BL. NF-kappa B / metabolism. Neutrophils / cytology, metabolism. Norepinephrine / immunology*. Phagocytes ... Isolation of mouse macrophages Peritoneal mouse macrophages were obtained using the thioglycollate method. Mice were injected ... Specific pathogen-free male C57BL/6 mice (Jackson Laboratories, Bar Harbor, ME) were used for data displayed in Figure 1 and ... Catecholamines Induce NFκB Activation and Release of Cytokines in Mouse Macrophages Following isolation, peritoneal mouse ...http://www.biomedsearch.com/nih/Upregulation-phagocyte-derived-catecholamines-augments/19212441.html
Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
Mice. Mice, Inbred C57BL. Mice, Transgenic. Mutation. Nerve Net / drug effects, physiology. Patch-Clamp Techniques. Peptides / ... 4E). MAP1b and αCamKII, were elevated in both Fmr1 KO mice and H1a/Fmr1 KO mice in comparison to WT and H1a KO mice (Fig. 4E) ... 6B; WT = 85±8 sec; n = 18 mice; Fmr1 KO = 138±12; n = 24; p, 0.01). H1a KO mice were not different than WT mice in this ... 14 slices from 7 mice; H1a KO 102±4% of WT, n=8 slices from 4 mice; double H1a/Fmr1 KO 106±6% of WT, n=7 slices from 4 mice; ...http://www.biomedsearch.com/nih/Disrupted-Homer-scaffolds-mediate-abnormal/22267161.html
Ecto-nucleotidase activities of promastigotes from Leishmania (Viannia) braziliensis relates to parasite infectivity and...
Mice. Mice, Inbred C57BL. Nitric Oxide / metabolism. Virulence Factors / biosynthesis*. Chemical. Reg. No./Substance: 0/Adenine ... Furthermore, we observed a positive correlation between the time for peak of lesion development in C57BL/6J mice and enzymatic ... Mice inoculated with PPS6m show delayed lesion development and present larger parasite loads than animals inoculated with the ...http://www.biomedsearch.com/nih/Ecto-Nucleotidase-Activities-Promastigotes-from/23071853.html
Ultrastructural study of spontaneous bone marrow rosette-forming cells.
Mouse bone marrow contains spontaneous rosette-forming cells (RFC) which include more than 70% T-cell precursors, as assessed ... Mice. Mice, Inbred C57BL. Mitochondria / ultrastructure. Ribosomes / ultrastructure. Comments/Corrections. From MEDLINE®/PubMed ... Mouse bone marrow contains spontaneous rosette-forming cells (RFC) which include more than 70% T-cell precursors, as assessed ... Such spontaneous RFC, examined in C57B1/6 mouse bone marrow by electron and scanning electron microscopy, have consistently ...http://www.biomedsearch.com/nih/Ultrastructural-study-spontaneous-bone-marrow/320218.html
Endothelial progenitor cell transplantation decreases lymphangiogenesis and adverse myocardial remodeling in a mouse model of...
Mice. Mice, Inbred C57BL. Mice, Transgenic. Myocardial Infarction / metabolism, physiopathology, therapy*. Real-Time Polymerase ... Mouse (C57bl/6J) MI models were created by ligation of the left anterior descending coronary artery and were treated with ... Endothelial progenitor cell transplantation decreases lymphangiogenesis and adverse myocardial remodeling in a mouse model of ... Lymphangiogenic markers increased in a mouse MI model. EPC transplantation decreased lymphangiogenesis and adverse ventricular ...http://www.biomedsearch.com/nih/Endothelial-progenitor-cell-transplantation-decreases/21694495.html
In vivo expression profile of an endothelial nitric oxide synthase promoter-reporter transgene.
Mice. Mice, Inbred C57BL. Mice, Transgenic. Mutagenesis, Insertional. Nephrons / enzymology. Nitric Oxide Synthase / genetics* ... Examination of beta-galactosidase expression in heart, lung, kidney, liver, spleen, and brain of adult mice demonstrated robust ...http://www.biomedsearch.com/nih/In-vivo-expression-profile-endothelial/10749733.html
Double dissociation of spike timing-dependent potentiation and depression by subunit-preferring NMDA receptor antagonists in...
Mice. Mice, Inbred C57BL. Nerve Net / physiology*. Neuronal Plasticity / physiology*. Receptors, N-Methyl-D-Aspartate / ... C57BL/6 mice were purchased from Harlan (Bicester, UK), and ranged in age from postnatal day (P)6 to P102. Mice were kept on a ... in P11-15 mice, whereas t-LTP induction was blocked (B; gray squares). NVP-AAM077 also did not block t-LTD in P6-8 mice (C; ... A, B) Ro 25-6981 (0.5 μM) did not affect t-LTD (A; gray triangles) or t-LTP (B; gray triangles) in P11-15 mice. (C) Summary of ...http://www.biomedsearch.com/nih/Double-Dissociation-Spike-Timing-Dependent/19363149.html
Activation of Wnt/β-catenin signalling affects differentiation of cells arising from the cerebellar ventricular zone.
Mice. Mice, Inbred C57BL. Neuroglia / metabolism. SOX9 Transcription Factor / metabolism. Wnt Signaling Pathway* / genetics. ... mouse anti-β-catenin (BD Biosciences, 1∶500), mouse anti-BrdU (BD Biosciences, 1∶50), mouse anti-Caspase3 (NEB, 1∶50) and mouse ... BAT-gal mice were maintained as hemizygotes on a C57BL/6J background and were genotyped as described previously . Mice ... We used a strain of mice harbouring the Apc580s conditional allele of Apc hereinafter referred to as Apclox. In these mice ...http://www.biomedsearch.com/nih/Activation-Catenin-Signalling-Affects-Differentiation/22880037.html
Embryonic stem cells improve cardiac function in Doxorubicin-induced cardiomyopathy mediated through multiple mechanisms.
Mice. Mice, Inbred C57BL. Myocytes, Cardiac / metabolism, pathology. Stem Cell Transplantation / methods*. ... We generated DIC in C57Bl/6 mice (cumulative dose of DOX 12 mg/kg body weight, IP), and animals were treated with ES cells, CM ...http://www.biomedsearch.com/nih/Embryonic-Stem-Cells-Improve-Cardiac/22449713.html
Electroacupuncture preconditioning reduces cerebral ischemic injury via BDNF and SDF-1α in mice. | CureHunter
Electroacupuncture preconditioning reduces cerebral ischemic injury via BDNF and SDF-1α in mice. - Ji Hyun Kim, Kyung Ha Choi, ... Mice, Inbred C57BL. *Vascular Endothelial Growth Factor A (metabolism) Join CureHunter, for free Research Interface BASIC ... Electroacupuncture preconditioning reduces cerebral ischemic injury via BDNF and SDF-1α in mice.. Abstract. BACKGROUND: This ... To assess the protective effects of EA against ischemic injury, the mice received once a day 20 min EA preconditioning for ...http://www.curehunter.com/public/pubmed23356671.do
mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia. | CureHunter
Mice. *Mice, Inbred C57BL. *Models, Biological. *Oxygen (metabolism) *Phosphotransferases (Alcohol Group Acceptor) (metabolism ...http://www.curehunter.com/public/pubmed19535330.do
Targeted imaging of breast tumor progression and therapeutic response in a human uMUC-1 expressing transgenic mouse model.
Mice. Mice, Inbred C57BL. Mice, Transgenic. Molecular Imaging*. Mucin-1 / metabolism*. Grant Support. ... This was done in mice that express human uMUC-1 tumor antigen (MMT mice) and develop spontaneous mammary carcinoma in a stage- ... In addition, T2 relaxation times were already altered at pre-malignant state in these mice compared to non-tumor bearing mice. ...http://www.biomedsearch.com/nih/Targeted-imaging-breast-tumor-progression/23015160.html
eNOS mediates L-arginine-induced inhibition of thick ascending limb chloride flux.
Mice. Mice, Inbred C57BL. Mice, Knockout. Nitric Oxide / metabolism. Nitric Oxide Synthase / genetics*, metabolism*. Nitric ... 2+/-15.8 pmol/mm per minute (P,0.01) in C57BL/6J wild-type mice, whereas addition of D-Arginine had no effects on J(Cl.) In ... THALs from male eNOS, iNOS, and nNOS knockout mice and C57BL/6J wild-type controls were perfused in vitro and the response of ... Addition of 0.5 mmol/L L-Arg to the bath decreased J(Cl) in THALs from iNOS and nNOS knockout mice by 37.7+/-6.4% (P,0.05) and ...http://www.biomedsearch.com/nih/eNOS-mediates-L-arginine-induced/10642318.html
The effects of colony-stimulating factor-1 on the distribution of mononuclear phagocytes in the developing osteopetrotic mouse.
Mice. Mice, Inbred C3H. Mice, Inbred C57BL. Organ Specificity. Osteoclasts / pathology. Osteopetrosis / blood, embryology, ... mouse. Fetal/neonatal mice, derived from matings of either +/csfmop females with csfmop/csfmop males or the reciprocal pairings ... 16557874 - Pathological changes in brain and other target organs of infant and weanling mice after.... 15285784 - Maternal ... gestational day-17 mothers were injected intravenously with 125I-mouse CSF-1 or human rCSF-1, and the 125I-cpm or human CSF-1 ...http://www.biomedsearch.com/nih/effects-colony-stimulating-factor-1/9573014.html
Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell...
Mice. Mice, Inbred C57BL. Mice, Inbred CBA. Organ of Corti / cytology*, pathology*. Regeneration / physiology. Time Factors. ... Studies were made with two different strains of mouse: CBA/Ca and C57BL/6. C57BL/6 are more susceptible to noise-induced hair ... C. C57BL/6 mouse, 4 weeks post-treatment. Head of tectal cell expanded (arrow) as far the first row Deiters' cell head. IHC are ... A. C57BL/6 mouse at 6 weeks post-treatment. Actin labelling in whole mount preparation of the apical coil. The arrow indicates ...http://www.biomedsearch.com/nih/Defining-Cellular-Environment-in-Organ/22299045.html
The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.
Mice. Mice, Inbred C57BL. Mice, Knockout. Naphthols / pharmacology. Phosphorylation / drug effects. Rats. Rats, Sprague-Dawley ... p53-null (8-10 weeks old, mixed background C57BL/6J and 129/Sv) mice were described previously (19). Homozygous wild-type (WT) ... A: Effects of intracerebroventricular AICAR injection (3 μg/mouse) on food intake after 6 h in p53 KO mice. B and C: ... Mice lacking p53 do not respond to ghrelin injection. Effects of intracerebroventricular ghrelin injection (5 μg/mouse) on food ...http://www.biomedsearch.com/nih/Central-Pathway-Essential-Orexigenic-Action/21386086.html
Role of nucleotide- and base-excision repair in genotoxin-induced neuronal cell death. | CureHunter
Mice. *Mice, Inbred C57BL. *Mice, Knockout. *Mutagens (toxicity) *Netropsin (analogs & derivatives, toxicity) ... Neuronal and astrocyte cell cultures prepared from the cerebellum of wild type (C57BL/6) mice or Aag(-/-) or Xpa(-/-) mice were ... Astrocytes from the cerebellum of wild type, Aag(-/-) or Xpa(-/-) mice were essentially insensitive to CAA at the ...http://www.curehunter.com/public/pubmed15135729.do
Tumor-infiltrating dendritic cell subsets of progressive or regressive tumors induce suppressive or protective immune responses...
Mice. *Mice, Inbred C57BL. *Mice, Inbred DBA. *Neoplasms, Experimental (immunology, pathology) *T-Lymphocyte Subsets ( ... Vaccination of mice with P815 tumor lysate-pulsed CD4+ 8+ TID815 or TID198 and CD4+ 8- TID198 induced IFN-gamma-secreting Th1 ... Transfer of CD4+ Tr1 cells obtained from CD4- 8- TID815-immunized wild-type, but not IL-10(-/-) mice, into CD4+ 8+ TID815 ... immunized mice abolished otherwise inevitable development of antitumor immunity. Taken together, our findings provide an ...http://www.curehunter.com/public/pubmed15930318.do
Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor...
Mice, Inbred C57BL. MESH. Mice, Knockout. MESH. Neural Stem Cells/cytology. MESH. ... and atypical teratoid/rhabdoid-like tumors from postnatal mouse neural stem/progenitor cells (NSC/NPC). We found that the ... and atypical teratoid/rhabdoid-like tumors from postnatal mouse neural .... ...https://epub.uni-regensburg.de/30586/