JCI - MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth
... normal human epidermal melanocytes (PromoCell) and normal melanocyte cultures hmel-p-16, Nohm-4 and Hermes-2B were maintained ... miR-432 in 26 melanoma cultures (black diamonds) and 4 normal melanocyte cultures (white squares). Threshold is set to the ... Results are expressed as fold above the average values in all normal melanocyte specimens. Cutoffs for overexpression and ... Indeed, chromosomal copy number analysis in 12 metastatic melanoma cell lines and 3 normal cell samples (melanocytes, HUVEC, ...https://www.jci.org/articles/view/62980
Clonal analyses reveal roles of organ founding stem cells, melanocyte stem cells and melanoblasts in establishment, growth and...
... melanocytes and total melanocytes were counted to determine the number of clones that make up the fin melanocytes. ... the kit-dependent melanocytes providing the bulk of the melanocyte pattern, whereas the kit-independent melanocytes having ... Melanocyte clones grow on the proximal-distal axis of the fin. We were first interested in the axis of growth of the melanocyte ... Here, 65% of melanocytes were GFP+ melanin-, compared with 30% and 12% unmelanized melanocytes in the middle and proximal ...http://dev.biologists.org/content/137/23/3931
Epidermis, melanocytes - Stock Video Clip K005/0014 - Science Photo Library
... dissolve on melanocytes. Melanocytes manufacture the pigment melanin, which helps filter dangerous ultraviolet, or uv. rays ... Caption: Pull out of epidermis in a cut-away model of the skin, dissolve on melanocytes. Melanocytes manufacture the pigment ... Keywords: capillary, dermis, epidermis, epithelial tissue, hypodermis, integumentary system, melanin, melanocytes, skin, ...http://www.sciencephoto.com/media/682080/view
Stimulation of melanogenesis by tetradecanoylphorbol 13-acetate (TPA) in mouse melanocytes and neural crest cells. - The...
In this study, we utilized primary cultures of neural crest cells and an immortalized melanocyte cell line (DMEL-2) which ... and stimulates proliferation and differentiation of normal melanocytes. As TPA is not a physiological agent, its action is ... investigating the long-term effects of TPA on melanogenesis and provides an understanding of how TPA enhances mouse melanocyte ... the expression of melanogenic genes will therefore provide valuable insight into the molecular mechanisms regulating melanocyte ...https://www.kennedy.ox.ac.uk/publications/107428
The Number of Melanocytes in Human Epidermis | The BMJ
The Number of Melanocytes in Human Epidermis Br Med J 1954; 1 :1016 ... The Number of Melanocytes in Human Epidermis. Br Med J 1954; 1 doi: https://doi.org/10.1136/bmj.1.4869.1016 (Published 01 May ...http://www.bmj.com/content/1/4869/1016
How to know if melanocytes remain - Dermatology - MedHelp
How to know if melanocytes remain. I scraped my nose about 3 months ago, and as a result of the injury the spot on my skin lost ...http://www.medhelp.org/posts/Dermatology/How-to-know-if-melanocytes-remain/show/1099030
A Direct Connection to Melanocytes
"We chose to use red-haired mice because they have a block on the surface protein of the melanocyte, which hinders their ability ... The major scientific breakthrough according to Fisher was that the target of UV rays was not found to be melanocytes but rather ... People with red hair usually have a variant form of the receptor protein on the melanocyte surface, and their variant form ... The way the researchers chose to target the enzymes in the melanocytes was through the topical compound forskolin, a derivative ...http://www.cosmeticsandtoiletries.com/formulating/function/active/216633161.html
α-MSH (α-Melanocyte-stimulating hormone) References
... α-Melanocyte-stimulating hormone) (ab120189). Please let us know if you have used this product in your publication ...http://www.abcam.com/alpha-msh-alpha-melanocyte-stimulating-hormone-ab120189-references.html
des-Ac-α-Melanocyte Stimulating Hormone ≥97% (HPLC) | Sigma-Aldrich
... des-Ac-α-Melanocyte Stimulating Hormone for your research needs. Find product specific information including CAS, MSDS, ... Cell Biology, Cell Signaling and Neuroscience, Immunomodulators, Ion Channel Modulating Peptides, Melanocyte Stimulating ...http://www.sigmaaldrich.com/catalog/product/sigma/m8267?lang=en®ion=US
IIVS | Know Your Skin Cells: III. The Melanocytes
The Melanocytes. 1809 post-template-default,single,single-post,postid-1809,single-format-standard,ajax_fade,page_not_loaded,, ... IIVS toxicologist and study director, Emilia Costin wrote about melanocytes, responsible for producing skin color for The ...http://iivs.org/2018/02/01/know-your-skin-cells-iii-the-melanocytes/
Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects
Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition ... Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin was first described by Azzopardi ... In vitro it has been shown that activated melanocyte growth factor stimulates the proliferation of the normal human melanocytes ... "The stimulation of normal human melanocyte proliferation in vitro by melanocyte growth factor from bovine brain," Journal of ...https://www.hindawi.com/journals/cripa/2012/427628/
Tracing human keratinocytes and melanocytes with carboxyfluorescein hydroxysuccinimidyl ester (CFSE) staining
CFSE-stained keratinocytes and CFSE-stained melanocytes were transplanted to human full thickness in vitro wounds either as ... The CFSE-staining of keratinocytes and melanocytes did not affect the viability, migration or proliferation of the cells. ... Viability and migration of CFSE-stained keratinocytes and melanocytes were investigated, and proliferation of the cells ... Sections from wounds with transplanted co-cultured keratinocytes and melanocytes were stained for pancytokeratin to distinguish ...http://liu.diva-portal.org/smash/record.jsf?pid=diva2:881355
Ginsenosides Rb1 and Rg1 Stimulate Melanogenesis in Human Epidermal Melanocytes via PKA/CREB/MITF Signaling
... Mao Lin,1,2 Bao- ... This study aimed to investigate the effects of ginsenosides Rb1 and Rg1 on melanogenesis in human melanocytes and their related ... By contrast, the cell viability of melanocytes remained unchanged. After exposure to Rb1 or Rg1, the protein levels of ... These findings indicated that Rb1 and Rg1 increased melanogenesis and tyrosinase activity in human melanocytes, which was ...https://www.hindawi.com/journals/ecam/2014/892073/abs/
Isolated focal melanocytes collection in the lacrimal sac | British Journal of Ophthalmology
1987) Melanocytes in the nasal cavity and paranasal sinus. Incidence and distribution in Japan. Acta Pathol Jpn 37:1105-1114. ... The origin of malignant melanoma of the sac is uncertain.2 Presumably, it can arise from nests of melanocytes located either ... Editor,-Although the presence of melanocytes located within and under the epithelium of the nasal cavity and paranasal sinuses ... The cells containing the pigment were confirmed to be melanocytes by the Fontana-Masson staining. ...http://bjo.bmj.com/content/84/3/337.1
MKK6 increases the melanocyte dendricity through the regulation of Rho family GTPases.
... Kim M.Y., Choi T.Y., Kim J.H., Lee J.H. ... BACKGROUND: Melanocyte dendrites serve as the principal conduit for melanosome transfer. The dendrite formation requires actin ... OBJECTIVE: The aim of this study is to investigate and explore the involvement of p38 MAPK in melanocyte dendrite formation. ... RESULTS: We investigated the effect of melanogenic inducers on melanocyte dendricity, using SK-mel-24 melanoma cells because ...http://www.uniprot.org/citations/20869211
Melanocyte and Children's skin and the sun with La Roche-Posay
Melanocyte, definition and possible consequences on Children's skin and the sun thanks to La Roche-Posay, the brand recommended ... Melanocyte. Melanocytes are cells that pigment the skin and hair. Located in the dermis or epidermis, as well as in the eyes, ...http://www.laroche-posay.com/beauty-glossary/Children-s-skin-and-the-sun/Melanocyte-gt78-w229.aspx
Increase in pituitary melanocyte-stimulating hormone activity of genetically obese ( ob/ob) mice | SpringerLink
Melanocyte-stimulating hormone (MSH) activity was measured in the pituitaries of genetically obese and lean control mice using ... Melanocyte-stimulating hormone (MSH) activity was measured in the pituitaries of genetically obese and lean control mice using ... Increase in pituitary melanocyte-stimulating hormone activity of genetically obese (ob/ob) mice. ...https://link.springer.com/article/10.1007/BF02004019
The tyrosinase enhancer is activated by Sox10 and Mitf in mouse melanocytes
... Murisier, F.; Guichard, S.; Beermann, F. ... Proper tyrosinase expression in melanocytes depends upon the presence of a DRE that is located at -15 kb and provides enhancer ... The terminal differentiation of melanocytes is associated with the transcriptional activation of genes responsible for pigment ... underlining the contribution of Sox10 to tyrosinase gene regulation in melanocytes. ...https://infoscience.epfl.ch/record/115182
Efficacy of Autologous Outer-Root-Sheath Melanocytes Transplantation in the Treatment of Vitiligo - Full Text View -...
Efficacy of Autologous Outer-Root-Sheath Melanocytes Transplantation in the Treatment of Vitiligo. This study has been ... This arm includes all patients sides (left or right) treated with autologous outer-root-sheath melanocytes suspension followed ... Double Blind Within-Subject Controlled Study of Autologous Hair Follicle Outer-Root-Sheath Melanocytes Transplantation in the ... Biological: Outer-Root-Sheath Melanocytes Suspension The treatment consists in depositing a suspension of autologous outer-root ...https://clinicaltrials.gov/ct2/show/NCT01923142?recr=Open&cond=%22Hypopigmentation%22&rank=16
Changes of organelles associated with the differentiation of epidermal melanocytes in the mouse | Development
... treated epidermal melanocytes of newborn mouse skin were carried out. The process of melanocyte differentiation from ... The epidermis of α-MSH-treated 3-day-old mice and normal 6-day-old mice contained melanocytes with numerous fully melanized ... Changes in other organelles in differentiating melanocytes were also noticeable. Golgi apparatus and RER (rough endoplasmic ... Melanoblasts containing unmelanized premelanosomes gradually decreased in number after birth, while the number of melanocytes ...http://dev.biologists.org/content/43/1/107
Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes. -...
Slp2-a is the most abundantly expressed of the Slp- and Slac2-family proteins in melanocytes and colocalizes with Rab27A on ... Loss of Slp2-a protein also induced a change in melanocyte morphology, from their normal elongated shape to a more rounded ... Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.. ... These results reveal the differential and sequential roles of Rab27A-binding proteins in melanosome transport in melanocytes. ...https://www.ncbi.nlm.nih.gov/pubmed/15543135?access_num=15543135&link_type=MED&dopt=Abstract
Neuropeptide Y, alpha-melanocyte-stimulating hormone, and monoamines in food intake regulation. | Sigma-Aldrich
Neuropeptide Y, alpha-melanocyte-stimulating hormone, and monoamines in food intake regulation.. [Eduardo J B Ramos, Michael M ... alpha-Melanocyte-stimulating hormone is a tridecapeptide cleaved from pro-opiomelanocortin that acts to inhibit food intake. ... α-Melanocyte stimulating hormone, ≥97% (HPLC) C77H109N21O19S ...https://www.sigmaaldrich.com/catalog/papers/15723758
Beta-carotene uptake and bioconversion to retinol differ between human melanocytes and keratinocytes.
... Andersson, E ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:90375
Cellular Grafts of Suspended Melanocytes and Keratinocytes in the Treatment of Vitiligo.
... M HASHEM GAMAL, M ABDEL-LATIF AMANY, ... "Cellular Grafts of Suspended Melanocytes and Keratinocytes in the Treatment of Vitiligo." Journal of Pan-arab League of ... "Cellular Grafts of Suspended Melanocytes and Keratinocytes in the Treatment of Vitiligo." JOURNAL OF PAN-ARAB LEAGUE OF ... HASHEM GAMAL M, ABDEL-LATIF AMANY M, Ongenae K, Naeyaert J. Cellular Grafts of Suspended Melanocytes and Keratinocytes in the ...https://biblio.ugent.be/publication/156505
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