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*  Selenium supplementation and the incidence of preeclampsia in pregnant Iranian women: a randomized, double-blind, placebo...
OBJECTIVE. Recent studies have reported that antioxidant status, including serum selenium concentrations, is altered in women who develop preeclampsia. We wished to examine the effects of selenium supplementation in the prevention of preeclampsia in high-risk pregnant women.. DESIGN. We carried out a randomized, double-blind, placebo-controlled pilot trial. A total of 166 primigravid pregnant women, who were in the first trimester of pregnancy, were randomized to receive 100 microg of selenium (n = 83; dropouts, n = 22) or a placebo (n = 83; dropouts, n = 19) per day until delivery. The incidence of preeclampsia, serum selenium concentrations, lipid profile and high-sensitivity C-reactive protein status were evaluated at baseline and at the end of the study.. RESULTS. Supplementation with selenium was not associated with any reported major side effects and was associated with a significant ...
  http://sro.sussex.ac.uk/41952/
*  Low serum albumin and the acute phase response predict low serum selenium in HIV-1 infected women | BMC Infectious Diseases |...
In this cross-sectional study of HIV-1-seropositive women, low serum selenium was independently associated with serum albumin and with the acute phase response, but not with CD4 count or plasma viral load. Further prospective studies may help determine whether associations between low serum selenium and low CD4 count [6, 9] and more advanced HIV-1 disease [10] could be related to the frequent occurrence of hypoalbuminemia and the acute phase response in people with advanced HIV-1 infection.. Several ingested forms of selenium, including selenomethionine, bind non-specifically to albumin for transport to the liver [11, 18-21]. The liver converts these compounds into selenocysteine, which is used to form various selenoproteins. In total, approximately 55% of selenium in human serum exists in selenoprotein P, another 17-32% exists bound to albumin, mostly in the form of selenomethionine, and only 10% of serum selenium is not ...
  https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-6-85
*  Selenium 200 mcg 90 vcapsules,ecological research Selenium supplements,cardio Selenium supplements,Selenium products,Selenium...
Selenium is a trace mineral that incorporates itself into proteins, making the proteins into antioxidant enzymes. These enzymes aid the body in fighting cellular damage from free radicals. Our selenium is in an amino acid form L-selenomethionine, which research indicates is better absorbed and more bioavailable compared to other forms of selenium.* Serving Size: 1 capsule Vitamin C (as Ascorbic Acid and Ascorbyl Palmitate) 250 mg Selenium (as L-Selenomethionine) 200 mg Other Ingredients: Vegetarian cellulose capsule. Directions: One capsule daily with a meal as a dietary supplement, or as directed by a Doctor.
  http://www.bayho.com/p/814119.html
*  Can Low Selenium Levels Trigger An Autoimmune Response? | Natural Thyroid Treatment/Graves Disease/Hashimotos Thyroiditis
While all of the minerals play an important role in the health of individuals, selenium is one of the more important minerals with regards to thyroid health. First of all, selenium is important in the formation of thyroid hormone, as well as the conversion of T4 to T3. Selenium is also important in the synthesis of glutathione. Epidemiological findings link a lowered selenium status to neurodegenerative and cardiovascular diseases as well as to increased cancer risk (1). Selenium is extremely important for optimal immune system health, and a selenium deficiency might make one more susceptible to developing an autoimmune condition such as Graves' Disease or Hashimoto's Thyroiditis.. How Does Selenium Enhance Immune Function?. While selenium has many different functions, this blog post will mainly focus on the benefits of selenium with regards to immune system ...
  http://www.naturalendocrinesolutions.com/archives/can-low-selenium-levels-trigger-an-autoimmune-response/?replytocom=14541
*  Can Low Selenium Levels Trigger An Autoimmune Response? | Natural Thyroid Treatment/Graves Disease/Hashimotos Thyroiditis
While all of the minerals play an important role in the health of individuals, selenium is one of the more important minerals with regards to thyroid health. First of all, selenium is important in the formation of thyroid hormone, as well as the conversion of T4 to T3. Selenium is also important in the synthesis of glutathione. Epidemiological findings link a lowered selenium status to neurodegenerative and cardiovascular diseases as well as to increased cancer risk (1). Selenium is extremely important for optimal immune system health, and a selenium deficiency might make one more susceptible to developing an autoimmune condition such as Graves' Disease or Hashimoto's Thyroiditis.. How Does Selenium Enhance Immune Function?. While selenium has many different functions, this blog post will mainly focus on the benefits of selenium with regards to immune system ...
  http://www.naturalendocrinesolutions.com/archives/can-low-selenium-levels-trigger-an-autoimmune-response/?replytocom=14560
*  Can Low Selenium Levels Trigger An Autoimmune Response? | Natural Thyroid Treatment/Graves Disease/Hashimotos Thyroiditis
While all of the minerals play an important role in the health of individuals, selenium is one of the more important minerals with regards to thyroid health. First of all, selenium is important in the formation of thyroid hormone, as well as the conversion of T4 to T3. Selenium is also important in the synthesis of glutathione. Epidemiological findings link a lowered selenium status to neurodegenerative and cardiovascular diseases as well as to increased cancer risk (1) [1]. Selenium is extremely important for optimal immune system health, and a selenium deficiency might make one more susceptible to developing an autoimmune condition such as Graves' Disease or Hashimoto's Thyroiditis.. How Does Selenium Enhance Immune Function?. While selenium has many different functions, this blog post will mainly focus on the benefits of selenium with regards to immune ...
  http://www.naturalendocrinesolutions.com/archives/can-low-selenium-levels-trigger-an-autoimmune-response/print/
*  Selenium - Health Encyclopedia - University of Rochester Medical Center
Consuming selenium from normal dietary sources doesn't seem to cause side effects. Consuming more than 200 mcg of selenium per day for a long period of time may cause side effects. These can include itchy skin, diarrhea, and weakening and loss of fingernails, hair, and teeth. Other symptoms can include nausea, vomiting, peripheral neuropathy, and fatigue. Selenium can also cause your breath to have a garlic-like odor. Adults who work in industrialized areas with high selenium content have a higher chance of liver and heart disease. Even though optimal amounts of selenium may reduce the risk of cancer, consuming too much can be harmful. It may increase the risk for cancer. Women who are pregnant or breastfeeding should talk to their healthcare providers before taking any supplements. Too much selenium can lead to bone and cartilage problems in unborn babies. Kidney problems can cause high ...
  https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=19&contentid=Selenium
*  No Clear Role for Selenium in Cancer Prevention - UNM Comprehensive Cancer Center
Some studies have suggested that people with higher selenium levels have a lower risk of certain types of cancer; a review conducted by the Cochrane Collaboration, however, found no clear evidence that selenium supplements provide a cancer benefit.. Selenium is a trace mineral that is important for human health. Small amounts are generally sufficient, and excess selenium may be harmful. Meats and breads are common sources of selenium in the United States.[1] Selenium may also be taken as a supplement.. Some studies have suggested that selenium-an antioxidant-may reduce the risk of certain types of cancer, such as prostate cancer and bladder cancer. Others studies, however, failed to find a benefit.. To summarize the available evidence, researchers evaluated 55 studies that involved a total of more than one million participants.[2] The studies with the most reliable results found that ...
  http://cancer.unm.edu/2011/05/17/no-clear-role-for-selenium-in-cancer-prevention/
*  Abstract P050: Association Between Circulating Selenium Levels and Primary Hypertension: A Meta-analysis | Hypertension
Background: Increasing evidence support the role of oxidative stress in the development of Primary hypertension (HTN). Selenium is an essential micronutrient with antioxidant properties mediated via selenoenzymes like glutathione peroxidases. It is hypothesized that selenium plays a role in blood pressure regulation and HTN prevention. We conducted a meta-analysis to evaluate the relationship between circulating selenium levels and HTN.. Methods: We searched MEDLINE, CINAHL and COCHRANE databases for studies reporting serum selenium levels in the patients with HTN and healthy controls. We calculated the weighted standardized mean difference (SMD) in the serum selenium levels between the HTN and control groups.. Results: Our search strategy yielded 313 articles and we included 10 studies enrolling 10420 participants. The median age of the HTN group was 57 yrs. (IQR 56-58) compared to 46 yrs. (IQR 42-50) in the control group. ...
  http://hyper.ahajournals.org/content/66/Suppl_1/AP050
*  Publication : USDA ARS
Citation: Taylor, J.B. 2005. Time-dependent influence of supranutritional organically bound selenium accumlation in growing wether lambs. Journal of Animal Science. 83:1186-1193. Interpretive Summary: Opportunities to supplement selenium to grazing sheep are sometimes limited in extensive North America range sheep operations. Feeding growing wethers 2.9 ug selenium/g dry matter, as high selenium wheat grain, increases the amount of selenium deposited in the body within 14 days, and enhances skeletal muscle selenium six-fold within 56 days. The strategic use of high selenium wheat grain to deliver supranutritional selenium levels, provides a readily available source of selenomethionine, and rapidly increases tissue selenium levels in wether lambs without adversely influencing performance. Such a selenium supplementation strategy could provide ...
  https://www.ars.usda.gov/research/publications/publication/?seqNo115=175201
*  Selenium Supplementation of Patients With Cirrhosis - Full Text View - ClinicalTrials.gov
Selenium is an essential nutrient that plays a role in oxidant defense, among other functions. There is much interest in the role selenium may play in several disease processes. It is possible that certain diseases result in selenium deficiency because of the form of selenium taken in the normal diet.. We propose to measure the selenium biomarkers associated with supplemental intakes of 200 or 400 µg of selenium per day in the chemical form selenate, or with supplemental intake of 200 µg selenium as selenomethionine. 144 patients with cirrhosis will be randomized to one of 4 treatment groups, including a placebo. After treatement for 4 weeks, all participants will receive 400 µg of selenium per day as selenate for 4 weeks. Blood will be measured initially and at 4 and 8 weeks. Selenium, selenoprotein P and glutathione peroxidase will be measured in the ...
  https://clinicaltrials.gov/ct2/show/NCT00212212
*  Selenium Supplementation of Patients With Cirrhosis - Full Text View - ClinicalTrials.gov
Selenium is an essential nutrient that plays a role in oxidant defense, among other functions. There is much interest in the role selenium may play in several disease processes. It is possible that certain diseases result in selenium deficiency because of the form of selenium taken in the normal diet.. We propose to measure the selenium biomarkers associated with supplemental intakes of 200 or 400 µg of selenium per day in the chemical form selenate, or with supplemental intake of 200 µg selenium as selenomethionine. 144 patients with cirrhosis will be randomized to one of 4 treatment groups, including a placebo. After treatement for 4 weeks, all participants will receive 400 µg of selenium per day as selenate for 4 weeks. Blood will be measured initially and at 4 and 8 weeks. Selenium, selenoprotein P and glutathione peroxidase will be measured in the ...
  https://clinicaltrials.gov/ct2/show/NCT00212212?term=selenium&rank=4
*  Selenium and Prostate Cancer: Clinical Trial on Availability to Prostate Tissue and Effects on Gene Expression - Full Text View...
Rationale: Prostate cancer is a frequently observed malignancy in men, especially in elderly men. Besides diagnosis and treatment, also prevention of prostate cancer is an important point of interest to reduce the incidence and mortality of prostate cancer. Selenium is considered to be a promising chemopreventive agent for prostate cancer. Exact mechanisms of chemoprevention by selenium are not fully understood. However, it is expected that selenium (among other effects) directly affects gene expression in the prostate.. Objective: The aim of this study is to get insight into bioavailability of selenium in prostate tissue and changes of gene expression profiles that might be responsible for selenium-induced chemoprevention. To meet this objective, the relationship between dietary selenium intake and changes in gene expression profiles, tissue selenium levels and blood flow in prostate tissue ...
  https://clinicaltrials.gov/ct2/show/NCT00446901?term=selenium&rank=17
*  Life Extension - Super Selenium Complex & Vitamin E - 200 Mcg - 100 Vcaps - A+A Wellness - East Cobb, Kennesaw, Marietta, and...
Super Selenium Complex 200 mcg Vitamin E by Life Extension 100 VegCap Super Selenium Complex 200 mcg Vitamin E 100 VegCap Super Selenium Complex with a new selenium blend that combines all three of these unique forms of selenium. A small amount of vitamin E is included because it has been shown to work synergistically with selenium.1 Caution If you are taking anti-coagulant or anti-platelet medications or have a bleeding disorder consult your healthcare provider before taking this product. Suggested Use As a dietary supplement Take one capsule per day with food - Or as directed by your healthcare professional. Supplement Facts Serving Size 1 vegetarian capsule Amount Per Serving Daily Value Vitamin E (as D-alpha tocopheryl succinate) 30 IU Selenium (as Se-Methyl L-Selenocysteine SelenoPure1 L-selenomethionine sodium selenite) 200 mcg (Selenium (L-selenomethionine1) 50 mcg) ...
  https://www.aandawellness.com/product/life-extension-super-selenium-complex-vitamin-e-200-mcg-100-vcaps/
*  Diabetes risk could be predicted by blood levels of selenium. The selenium content of normal adult humans can vary widely.
The selenium content of normal adult humans can vary widely. Values from 3mg in New Zealanders to 14mg in some Americans reflect the profound influence of the natural environment on the selenium contents of soils, crops, and human tissues.
  http://ndri.com/news/diabetes_risk_could_be_predicted_by_blood_levels_of_selenium-264.html
*  Selenium, multi-vitamins and soy protect the prostate - Nutrition Express Articles
Men who had high levels of selenium, multi-vitamins, vitamin E and soy isoflavones had lower risk for prostate cancer than men with low levels of these nutrients in two new studies. Soy isoflavones slowed the growth of prostate-cancer cells in a third new study. In the selenium study, researchers measured the blood fluid (serum) levels of selenium in 724 men with prostate cancer and in 879 healthy men of the same age who entered the study at the same time, and followed up for eight years. Scientists found that men who had higher selenium levels who also reported taking multi-vitamins had 39% lower risk for prostate cancer than men with the lowest selenium levels. Doctors also found that men with higher selenium levels who reported taking more than 28 IU of vitamin E per day had 42% lower risk for prostate cancer than men with the lowest selenium levels. Men with higher ...
  https://www.nutritionexpress.com/showarticle.aspx?articleid=888
*  Scientific Opinion on Dietary Reference Values for selenium | European Food Safety Authority
Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) derived Dietary Reference Values (DRVs) for selenium. The levelling off of plasma selenoprotein P (SEPP1) concentration was considered indicative of an adequate supply of selenium to all tissues and to reflect saturation of the functional selenium body pool, ensuring that selenium requirement is met. This criterion was used for establishing DRVs for selenium in adults. Evidence from human studies on the relationship between selenium intake and plasma SEPP1 concentration was reviewed. Given the uncertainties in available data on this relationship, they were considered insufficient to derive an Average Requirement. An Adequate Intake (AI) of 70 µg/day for adults was set. A review of observational studies and randomised controlled trials that investigated the relationship between ...
  http://www.efsa.europa.eu/en/efsajournal/pub/3846
*  Selenium supplementation for asthma | Cochrane
Selenium is a trace mineral, and it is thought that deficiency of selenium may play some role in the development of asthma. Some studies suggest that selenium supplementation for people with chronic asthma may help to improve symptoms. This review found some evidence from only one small trial that selenium supplementation might help reduce symptoms of chronic asthma symptoms, but more research is needed to be certain.. ...
  http://www.cochrane.org/CD003538/AIRWAYS_selenium-supplementation-for-asthma
*  Serum Selenium Concentrations and Diabetes in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2003-2004
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2737018/?lang=en-ca
*  Effect of selenium depletion and supplementation on the kinetics of type 1 5′-iodothyronine deiodinase and T3/T4in rats |...
Presently, the effect of selenium (Se) deficiency and excess of Se (1 ppm) on the activity of selenoenzymes type 1 5′-iodothyronine deiodinase (5′-DI), glutathione peroxidase (GSH-Px), and level of thyroid hormones (T3 and T4) was studied in rats. Se levels in the serum and liver, T3 and T4 in the serum, GSH-Px levels in the liver, and 5′-DI activity in the liver/aorta/thyroid were estimated after 1, 2, and 3 mo of Se-deficient (0.02 ppm), Se-adequate (0.2 ppm), and Se-excess (1 ppm) diet feeding. All of these parameters decreased significantly in the Se-deficient group as compared to the adequate group. Within the deficient group, as the Se deficiency progressed, all of the parameters except 5′-DI decreased after 2 and 3 mo in comparison to 1-mo data. Thyroidal 5′-DI activity in Se deficiency showed the maximum increase. A significant increase was observed in all of the above parameters in the 1 ppm Se-supplemented diet group when compared with the adequate Se group; also, as the Se ...
  https://link.springer.com/article/10.1385%2FBTER%3A97%3A1%3A95
*  New study shows strong link between selenium levels and depression - Healthcanal.com : Healthcanal.com
Dr Tamlin Conner Otago's Department of Psychology co-author and study lead Dr Tamlin Conner says the research reinforces links between both low and high selenium status and adverse health effects in humans - including on mood, which is her main area of expertise. A total of 978 young adults aged 17 to 25 were asked to complete a depression questionnaire and track their mood daily over the Internet for two weeks. Blood tests were also taken to determine their selenium levels. The results of this research, a collaboration between the University's Psychology and Human Nutrition departments, and published in the prestigious Journal of Nutrition today, suggests that there is a relationship between selenium concentration and depressive symptoms and negative mood among young adults. Young adults with either too low, or too high, levels of selenium showed the highest risk of depressive symptoms and poorer mood. However, lower ...
  https://www.healthcanal.com/mental-health-behavior/depression/57077-new-study-shows-strong-link-between-selenium-levels-and-depression.html
*  HIGH SELENIUM....WITHOUT SUPPLEMENTING - Thyroid UK | HealthUnlocked
i have high selenium without taking a selenium separate supplement and only a multi vitamin and fishoil , flaxseed oil, saw palmetto and evening primrose oil and viviscal pro with oyster powder and...
  https://healthunlocked.com/thyroiduk/posts/134054671/high-selenium....without-supplementing
*  Selenium by Source Naturals (Selenium Supplement) - ProHealth.com
Selenium is a trace mineral that supports healthy immune system activity, functions as a part of the potent antioxidant glutathione, and is necessary for good thyroid health. This formula uses 100% yeast free SelenoPure high selenium for ultim
  https://www.prohealth.com/shop/product.cfm/product__code/N0314
*  Plus it
2508 Numerous selenium-containing compounds are being investigated as cancer chemopreventive agents in both laboratory studies and clinical investigations. In many of these studies, drug- or nutrient-induced increases in blood selenium levels are associated with tumor inhibition. Previous small scale clinical studies have indicated that selenium-containing agents are also effective at increasing glutathione levels in blood and tissues, resulting in decreased levels of oxidative stress. Our objectives were to examine the relationship between blood selenium levels and glutathione status in healthy free-living individuals and in subjects administered selenium-enriched yeast as a dietary supplement. In the first study, 336 healthy adults between 18-50 yr of age (161 Blacks, 175 Whites; 168 females, 168 males) were recruited as part of a community-based study of smoking biomarkers and health. Blood selenium ...
  http://cancerres.aacrjournals.org/content/67/9_Supplement/2508
*  Glutathione peroxidase activity, and content of total and soluble selenium in five bovine and porcine organs used in meat...
article{54d39bb4-e7b5-47ae-988a-5e66994332e3, abstract = {Glutathione peroxidase (GSHPx) activity, and total and soluble selenium content were compared in five bovine and porcine organs. The highest GSHPx activity in porcine tissues was found in the liver (35.0 U/g), spleen (29.3 U/g) and kidney (27.3 U/g) with much lower values in the heart (1.8 U/g) and diaphragm (0.8 U/g). A different pattern with lower inter-organ variation in GSHPx activity was observed in cattle: kidney (8.5 U/g), spleen (8.0 U/g), heart (5.8 U/g), liver (4.0 U/g) and diaphragm (2.1 U/g). The total selenium content was similar in both species with the highest content in the kidney (1764 and 1665 ng/g; pig/bovine), followed by liver (533 and 307 ng/g), spleen (370 and 284 ng/g), heart (201 and 205 ng/g) and diaphragm (144 and 116 ng/g). The percentage of soluble selenium varied more among the pig organs (46-94%) than among bovine organs (61-75%). The results show a marked variation in ...
  https://lup.lub.lu.se/search/publication/286327