*  Institute of Cancer Research Repository - Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition...
CELLS PROSTATE-CANCER 3-KINASE/MAMMALIAN TARGET MALIGNANT-TRANSFORMATION RAPAMYCIN INHIBITOR HISTONE H3.3 GRADE GLIOMA DNA- ...
  http://publications.icr.ac.uk/16137/
*  Mammalian DNA Polymerase α Holoenzyme | SpringerLink
DNA replication as a macromolecular process requires the concerted action of many enzymes and proteins either alone or in a ... complex (1). These include e.g. DNA polymerases, DNA polymerase accessory... ... 1984) Mammalian DNA Polymerase α Holoenzyme. In: Proteins Involved in DNA Replication. Advances in Experimental Medicine and ... DNA-binding proteins, ribonuclease H, DNA ligase and others (1). Using the DNA of small bacteriophages of Escherichia coli and ...
  https://link.springer.com/chapter/10.1007/978-1-4684-8730-5_33
*  Antigenic Relationships in Mammalian DNA Polymerase | Science
... common antigenic determinants exist in the DNA polymerases from all mammalian sources, and (iii) multiple forms of DNA ... and high-molecular-weight DNA polymerases isolated from cytoplasmic and nuclear fractions of a number of mammalian tissues ( ... Rabbit antibody was prepared against a high-molecular-weight DNA polymerase purified from the soluble fraction of calf thymus ... no antigenic relationship exists between terminal transferase and DNA polymerase, (ii) ...
  http://science.sciencemag.org/content/175/4026/1116
*  Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays |...
Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays. ... The characterized compounds were screened to identify if they interfere with mammalian type I DNA topoisomerase activity via in ... Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays ... Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays ...
  http://clincancerres.aacrjournals.org/content/14/19_Supplement/A16
*  Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation...
The purpose of this study was to recapitulate our in vitro findings by introducing 5-chlorocytosine residues into the DNA of ... Investigations of inflammation-mediated DNA damage may have provided important new insights. Our in vitro studies revealed that ... Investigations of inflammation-mediated DNA damage may have provided important new insights.... ... replicating mammalian cells and to examine its impact on gene expression and cytosine methylation patterns. CHO-K1 cells ...
  http://oxfordindex.oup.com/view/10.1093/carcin/bgp060
*  Expression of a mammalian DNA photolyase confers light-dependent repair activity and reduces mutations of UV-irradiated shuttle...
... we expressed a marsupial DNA photolyase in DNA repair-deficient group A xeroderma pigmentosum (XP-A) cells. Expression of the ... photolyase and visible light irradiation removed CPD from cellular DNA and elevated survival of the UV-irradiated XP-A cells, ... Photoreactivation is one of the DNA repair mechanisms to remove UV lesions from cellular DNA with a function of the DNA ... Photoreactivation is one of the DNA repair mechanisms to remove UV lesions from cellular DNA with a function of the DNA ...
  https://www.semanticscholar.org/paper/Expression-of-a-mammalian-DNA-photolyase-confers-of-Asahina-Han/ff474ea878e092654e6a1cfe35c234fbb305cf5e
*  Human Spy1 Promotes Survival of Mammalian Cells following DNA Damage | Cancer Research
These proteins serve as DNA sensors, and are activated during both DNA replication and DNA damage events. Therefore, Spy1 may ... Human Spy1 Promotes Survival of Mammalian Cells following DNA Damage. Elizabeth A. Barnes, Lisa A. Porter, Jean-Luc Lenormand, ... Human Spy1 Promotes Survival of Mammalian Cells following DNA Damage. Elizabeth A. Barnes, Lisa A. Porter, Jean-Luc Lenormand, ... Human Spy1 Promotes Survival of Mammalian Cells following DNA Damage. Elizabeth A. Barnes, Lisa A. Porter, Jean-Luc Lenormand, ...
  http://cancerres.aacrjournals.org/content/63/13/3701
*  XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. - PubMed - NCBI
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells.. Pierce AJ1, Johnson RD, Thompson LH, Jasin M. ... Genomic DNA was digested with the indicated endonucleases. (Lanes 1,2,5,6) Untransfected wild-type cell line DRaa-40; (lanes 3, ... repair of DNA damage has recently emerged as a major mechanism for the maintenance of genomic integrity in mammalian cells. The ... The DRirs-14 cell line was electroporated with each of the indicated expression vectors (20 μg). The total amount of DNA ...
  https://www.ncbi.nlm.nih.gov/pubmed/10541549
*  "Calling Cards" for DNA-Binding Proteins in Mammalian Cells |...
"Calling Cards" for DNA-Binding Proteins in Mammalian Cells. Haoyi Wang, David Mayhew, Xuhua Chen, Mark Johnston and Robi David ... "Calling Cards" for DNA-Binding Proteins in Mammalian Cells. Haoyi Wang, David Mayhew, Xuhua Chen, Mark Johnston and Robi David ... "Calling Cards" for DNA-Binding Proteins in Mammalian Cells. Haoyi Wang, David Mayhew, Xuhua Chen, Mark Johnston and Robi David ... "Calling Cards" for DNA-Binding Proteins in Mammalian Cells Message Subject (Your Name) has forwarded a page to you from ...
  http://www.genetics.org/content/190/3/941
*  Effects of methotrexate on transfected DNA stability in mammalian cells
... Pallavicini, M. G.; DeTeresa, P. S.; Rosette, C.; Gray ... Keywords: Animals ; DNA Probes ; DNA ; Recombinant/genetics ; Gene Amplification/*drug effects ; Gene Expression Regulation/ ...
  https://infoscience.epfl.ch/record/104996
*  FARA - Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells
Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells Details Written by Jen Farmer Category: ... Rea More: Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells ... Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells ...
  http://www.curefa.org/scientific-news/effects-of-friedreich-s-ataxia-gaa-repeats-on-dna-replication-in-mammalian-cells
*  DNA Modification in Mammalian Brain by Bio Synthesis - HTML preview, Page 1
Read DNA Modification in Mammalian Brain, by Bio Synthesis in HTML for FREE. Also available in PDF, ePub and Kindle formats. ... DNA Modification in Mammalian Brain by Bio Synthesis - HTML preview. / Home / Free Previews / DNA Modification in Mammalian ...
  https://www.free-ebooks.net/ebook/DNA-Modification-in-Mammalian-Brain/html
*  PLOS Genetics: PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells
... a sliding DNA clamp that tethers the DNA polymerases to DNA, which functions to recruit the TLS DNA polymerase to the damaged ... A major universal tolerance mechanism is translesion DNA synthesis (TLS), in which specialized low-fidelity DNA polymerases ... In cases when the removal of DNA damage and restoration of the original sequence prior to replication is impossible, cells ... Here we show that in mammalian cells the modification of PCNA by ubiquitin is important, but there exist secondary yet ...
  http://journals.plos.org/plosgenetics/article/authors?id=10.1371/journal.pgen.1002262&imageURI=info:doi/10.1371/journal.pgen.1002262.g006
*  Isolation of High-Molecular-Weight DNA from Mammalian Cells Using Proteinase K and Phenol
Analysis of DNA Methylation in Mammalian Cells893 *Protocol 1: DNA Bisulfite Sequencing for Single-Nucleotide-Resolution DNA ... Panel: Analysis of DNA Methylation in Mammalian Cells893 *Panel: DNA Methylation Affects and Reveals Biological Phenomena894 * ... Isolation of High-Molecular-Weight DNA from Mammalian Cells Using Proteinase K and Phenol. (Protocol summary only for purposes ... Protocol 3: Isolating DNA from Gram-Negative Bacteria (e.g., E. coli) *Protocol 4: Precipitation of DNA with Ethanol *Protocol ...
  http://www.molecularcloning.com/index.php?prt=261
*  Agencourt<sup>®</sup> DNAdvance System Delivers High DNA Recovery From Mammalian Tissue Samples |...
introduces the Agencourt ® DNAdvance System, a new extraction kit for DNA isolation and purification from mammalian tissue ... introduces the Agencourt® DNAdvance System, a new extraction kit for DNA isolation and purification from mammalian tissue ... Product News: Agencourt® DNAdvance System Delivers High DNA Recovery From Mammalian Tissue Samples. ... "Many projects are using knock-out mice for genotyping studies but DNA extraction from a mouse tail can be difficult," explained ...
  http://www.selectscience.net/product-news/agencourt---dnadvance-system-delivers-high-dna-recovery-from-mammalian-tissue-samples/?artID=15661
*  Parvoviral Probe of DNA Replication in Mammalian Cells Exposed to Genotoxic Agents | Springer for Research & Development
Exposure of mammalian cells to a variety of chemical and physical agents depresses the overal rate of DNA synthesis [1]. Part ... Exposure of mammalian cells to a variety of chemical and physical agents depresses the overal rate of DNA synthesis [1]. Part ... A. R. Lehmann, Postreplication repair of DNA in ultraviolet-irradiated mammalian cells, J. Mol. Biol., 66: 319 (1972).PubMed ... S. L. Rhode, H-1 DNA synthesis, in: "Replication of Mammalian Parvoviruses," D. C. Ward and P. Tattersall, eds., p. 279, Cold ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-1117-2_18
*  Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells. | Molecular Pharmacology
Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells.. J W Lawrence, D C Claire, V ... Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells.. J W Lawrence, D C Claire, V ... Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells.. J W Lawrence, D C Claire, V ... Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells. ...
  http://molpharm.aspetjournals.org/content/50/5/1178.long
*  Visualizing inhibition of nucleosome mobility and transcription by cisplatin-DNA interstrand crosslinks in live mammalian cells...
Visualizing Inhibition of Nucleosome Mobility and Transcription by Cisplatin-DNA Interstrand Crosslinks in Live Mammalian Cells ... Visualizing Inhibition of Nucleosome Mobility and Transcription by Cisplatin-DNA Interstrand Crosslinks in Live Mammalian Cells ... Visualizing Inhibition of Nucleosome Mobility and Transcription by Cisplatin-DNA Interstrand Crosslinks in Live Mammalian Cells ... Visualizing Inhibition of Nucleosome Mobility and Transcription by Cisplatin-DNA Interstrand Crosslinks in Live Mammalian Cells ...
  https://www.ncbi.nlm.nih.gov/pubmed/23695549
*  Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories...
HeLa cell DNA was also analysed by an enzymic approach, in which whole cell DNA was treated with formamidopyrimidine DNA ... A tendency for DNA oxidation to occur during sample preparation prior to chromatography has been recognized as the source of a ... A tendency for DNA oxidation to occur during sample preparation prior to chromatography has been recognized as the source of a ... Chromatographic analysis of HeLa cell DNA gave a range of 1.84 to 214 per 106 guanines with a median of 5.23 per 106 guanines. ...
  http://oxfordindex.oup.com/view/10.1093/carcin/23.12.2129
*  Meta-analysis discovery of tissue-specific DNA sequence motifs from mammalian gene expression data | BMC Bioinformatics | Full...
... regulatory DNA motifs in all 18 tissue-specific expression clusters that we examined. For previously known TFBS motifs, we ... to their DNA recognition sites. However, elucidating TF binding site (TFBS) motifs in higher eukaryotes has been challenging, ... are likely to be co-regulated by orthologous TFs that bind to DNA sequence motifs present within noncoding sequence conserved ... Identification of DNA motifs within mammalian tissue-specific expression clusters. The GNF SymAtlas generated by the Genomics ...
  https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-7-229
*  Processing of Damaged DNA Ends for Double-Strand Break Repair in Mammalian Cells
Ku binds to DNA ends and recruits DNA-PKcs, the XRCC4/DNA ligase IV complex, and XLF. Synapsis of two DSB ends triggers DNA- ... "Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks," ... "Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV," EMBO Journal, vol. 23, no ... implications for DNA-PK-dependent processing of DNA termini in NHEJ-catalyzed DSB repair," DNA Repair, vol. 9, no. 6, pp. 670- ...
  https://www.hindawi.com/journals/isrn/2012/345805/
*  British Library EThOS: Analysis of the relationship between pluripotency and DNA damage tolerance recombination in mammalian...
One of the most threatening DNA lesions to the cell is DNA doublestrand break {DSB}. The repair of these DNA lesions in mouse ... The repair of DNA DSBs or stalled DNA replication fork is often mediated by the formation of Holliday junctions {HJs}. The ... Analysis of the relationship between pluripotency and DNA damage tolerance recombination in mammalian stem cells ... When using the correct DNA sequence as a template for DNA DSB repair, HR is of a high fidelity, otherwise it may lead to ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612608
*  Evidence of existence and compactness of dna superstructure units in mammalian cells a micro dosimetric approach to radiation...
Evidence of existence and compactness of dna superstructure units in mammalian cells a micro dosimetric approach to radiation ... induced dna release assayed by neutral sucrose gradient sedimentation ... Chen R.; Cole A., 1979: Speed dependence and wall effects for sedimentation of mammalian cell duplex dna in neutral sucrose ... Regel, K.; Günther, K.; Kampf, G., 1983: Evidence for existence and compactness of DNA superstructure units in mammalian cells ...
  https://eurekamag.com/research/005/411/005411398.php
*  ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair. - PubMed - NCBI
ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair.. Stark JM1, Hu P, Pierce AJ, Moynahan ME ... Thus, ATP hydrolysis by RAD51 has a key role in various types of DNA repair in mammalian cells. ... We found that these cells have increased sensitivity to the DNA-damaging agents mitomycin C and ionizing radiation and also ... we have begun a functional analysis of a defined RAD51 mutation in mammalian cells. By using a dominant negative approach, we ...
  https://www.ncbi.nlm.nih.gov/pubmed/11923292
*  James Hutchins - Mendeley
... with research interests in Nuclear structure and function and DNA replication, on Mendeley. ... MCM9 Is Required for Mammalian DNA Mismatch Repair.. *Traver S. *Coulombe P ... protein function databasesproteomics and phosphoproteomicscell divisionDNA replicationNuclear structure and function ...
  https://www.mendeley.com/profiles/james-hutchins/