*  MUC1 (EMA) is preferentially expressed by ALK positive anaplastic large cell lymphoma, in the normally glycosylated or only...
Although MUC1 is defined as an epithelial antigen, in 1984 Delsol et al reported that lymphoid cells and malignancies express ... Systemic (nodal) anaplastic large cell lymphoma (ALCL) is a CD30 positive non-Hodgkin's lymphoma of T cell or null cell ... Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma. ... Staining for anti-MUC1 monoclonal antibodies in tumour cells of ALK positive systemic nodal anaplastic large cell lymphoma ...
  http://jcp.bmj.com/content/54/12/933
*  Alisertib in Treating Patients With Relapsed or Refractory Peripheral T-Cell Non-Hodgkin Lymphoma - Full Text View -...
Lymphoma, Non-Hodgkin. Lymphoma, T-Cell. Leukemia, T-Cell. Leukemia-Lymphoma, Adult T-Cell. Lymphoma, Large-Cell, Anaplastic. ... Alisertib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. ... Anaplastic Large Cell Lymphoma Angioimmunoblastic T-Cell Lymphoma Hepatosplenic T-Cell Lymphoma Mature T-Cell and NK-Cell Non- ... Peripheral T-cell NHL (PTCL) not otherwise specified (NOS). *Anaplastic large cell T-cell lymphoma (ALCL) that is anaplastic ...
  https://clinicaltrials.gov/show/NCT01466881
*  Alisertib in Treating Patients With Relapsed or Refractory Peripheral T-Cell Non-Hodgkin Lymphoma - Full Text View -...
Lymphoma, Non-Hodgkin. Lymphoma, T-Cell. Leukemia, T-Cell. Leukemia-Lymphoma, Adult T-Cell. Lymphoma, Large-Cell, Anaplastic. ... Alisertib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. ... Anaplastic Large Cell Lymphoma Angioimmunoblastic T-Cell Lymphoma Hepatosplenic T-Cell Lymphoma Mature T-Cell and NK-Cell Non- ... T-cell, Chronic Adult T-cell Leukemia/lymphoma Extranodal Nasal NK/T Cell Lymphoma Anaplastic Large Cell Lymphoma ...
  https://clinicaltrials.gov/ct2/show/study/NCT01466881?show_locs=Y
*  ALK− anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell...
... since its original description in 1985 by Stein and colleagues1 as a lymphoma characterized by large anaplastic lymphoid cells ... Molecular biology of anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma. J Clin Oncol 2002;20:3691-3702. ... Anaplastic large cell lymphomas lack the expression of T-cell receptor molecules or molecules of proximal T-cell receptor ... Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma. ...
  http://www.bloodjournal.org/content/111/12/5496.long?sso-checked=true
*  Pathobiology of Hodgkin Lymphoma
... but reacted with a variety of lymphoid tumors, including anaplastic large-cell lymphoma (ALCL) [50-52] and nonlymphoid tumors ... However, although HRS cells are B lymphoid cells, they are unlike any normal B cell. Furthermore, their characteristics ... The borders between cHL and anaplastic large-cell lymphoma have become sharper, whereas those between LP-HL and T-cell-rich B- ... positive anaplastic large-cell lymphoma: implications for the differential diagnosis between lymphoid and nonlymphoid ...
  https://www.hindawi.com/journals/ah/2011/920898/
*  Search of: 'Anaplastic large cell lymphoma' - List Results - ClinicalTrials.gov
Anaplastic Large Cell Lymphoma and Other CD30+Peripheral T-Cell Lymphomas. *Malignant Neoplasms Stated as Primary Lymphoid ... Anaplastic Large Cell Lymphoma, ALK-Positive. *CD30-Positive Neoplastic Cells Present. *Systemic Anaplastic Large Cell Lymphoma ... s Lymphoma or Anaplastic Large Cell Lymphoma'. *Relapsed or Refractory CD30+ Hodgkin's Lymphoma or Anaplastic Large Cell ... A Study of Treatment ALK(+) Systemic Anaplastic Large Cell Lymphoma With Crizotinib. *Systemic Anaplastic Large-Cell Lymphoma ...
  https://clinicaltrials.gov/ct2/results?cond=%22Anaplastic+large+cell+lymphoma%22&show_rss=Y&sel_rss=new14
*  HOXC4 - Wikipedia
... and HOXC6 expression in primary cutaneous lymphoid lesions. High expression of HOXC5 in anaplastic large-cell lymphomas". Am. J ... 2 enhancer in human B cells. Relevance to class switch DNA recombination". J. Biol. Chem. 279 (40): 42258-69. doi:10.1074/jbc. ... Cell Genet. 73 (1-2): 114-5. doi:10.1159/000134320. PMID 8646877. Bijl JJ, Rieger E, van Oostveen JW, Walboomers JM, Kreike M, ... Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551-3. doi:10.1016/0092-8674(92)90588-4. PMID ...
  https://en.wikipedia.org/wiki/HOXC4
*  2018 ICD-10-CM Diagnosis Code C84.6: Anaplastic large cell lymphoma, ALK-positive
... consisting of usually large anaplastic, cd30 positive cells. The majority of cases are positive for the anaplastic large cell ... Malignant neoplasms of lymphoid, hematopoietic and related tissue. Type 2 Excludes*Kaposi's sarcoma of lymph nodes (C46.3) ... Anaplastic large cell lymphoma, ALK-positive. 2016 2017 2018 Non-Billable/Non-Specific Code *C84.6 should not be used for ... Other specified types of T/NK-cell lymphoma. 2016 2017 2018 Non-Billable/Non-Specific Code Type 1 Excludes*anaplastic large ...
  http://www.icd10data.com/ICD10CM/Codes/C00-D49/C81-C96/C84-/C84.6
*  Pathobiology of Anaplastic Large Cell Lymphoma
... evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells," Blood, vol. 66, no ... "Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells," ... gene expression in anaplastic lymphoma kinase-positive and anaplastic lymphoma kinase-negative anaplastic large cell lymphomas ... Anaplastic large cell lymphoma (ALCL) is a peripheral T-cell-derived malignancy, representing around 2%-3% of all lymphoid ...
  https://www.hindawi.com/journals/ah/2010/345053/
*  CD4 T-Helper Responses to the Anaplastic Lymphoma Kinase (ALK) Protein in Patients with ALK-Positive Anaplastic Large-Cell...
Anaplastic large cell lymphoma. Pathology and genetics. Tumors of haematopoietic and lymphoid tissues. International ... in patients with ALK-positive anaplastic large-cell lymphoma (ALCL). However, because CD4+ T-helper (Th) cells also play a ... Anaplastic large-cell lymphoma (ALCL) comprises 30% to 40% of pediatric large-cell lymphomas. The majority of ALCL are ... In vivo T-cell immune response against anaplastic lymphoma kinase in patients with anaplastic large cell lymphomas. ...
  http://cancerres.aacrjournals.org/content/67/5/1898
*  Anaplastic large-cell lymphoma - Wikipedia
Anaplastic large-cell lymphoma (ALCL) is a type of non-Hodgkin lymphoma involving aberrant T cells or null lymphocytes. It is ... described in detail in the "Classification of Tumours of the Haematopoietic and Lymphoid Tissues" edited by experts of the ... It has been suggested that ALK-negative anaplastic large-cell lymphomas derive from other T-cell lymphomas that are morphologic ... European T-Cell Lymphoma Study Group (2012). "ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma". Front Oncol ...
  https://en.wikipedia.org/wiki/Anaplastic_large-cell_lymphoma
*  Brentuximab Vedotin (SGN-35) in Patients With Relapsed or Refractory Systemic Anaplastic Large-Cell Lymphoma: Results of a...
... is an aggressive subtype of T-cell lymphoma characterized by the uniform expression of CD30. The antibody-drug conjugate ... British Columbia Cancer Agency Center for Lymphoid Cancer, Vancouver, British Columbia, Canada.. ... conjugate brentuximab vedotin delivers the potent antimicrotubule agent monomethylauristatin E to CD30-positive malignant cells ... PURPOSESystemic anaplastic large-cell lymphoma (ALCL) is an aggressive subtype of T-cell lymphoma characterized by the uniform ...
  http://www.biomedsearch.com/nih/Brentuximab-Vedotin-SGN-35-in/22614995.html
*  Primary CD30 (Ki-1)-positive anaplastic large cell lymphoma of the duodenum | SpringerLink
Ki-1 anaplastic large cell lymphoma (ALCL) commonly affects the skin, lymph nodes, and bone. Primary ALCL of the alimentary ... Evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 66:848-858, ... duodenal lymphoma anaplastic large cell lymphoma immunohistochemistry Ki-1 positive CD30 antigen extranodal lymphoma ... Cytokeratin expression and vimentin content in large cell anaplastic lymphomas and other non-Hodgkin's lymphomas. Am J Pathol ...
  https://link.springer.com/article/10.1007/BF02100125
*  Prognostic impact of minimal disseminated disease and immune response to NPM-ALK in Japanese children with ALK-positive...
... antibody titer in children with ALK-positive anaplastic large cell lymphoma (ALCL) was reported... ... Prognostic significance of circulating tumor cells in bone marrow or peripheral blood as detected by qualitative and ... World Health Organization (WHO) Classification of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press; 2008. p. ... and anti-anaplastic lymphoma kinase (ALK) antibody titer in children with ALK-positive anaplastic large cell lymphoma (ALCL) ...
  https://rd.springer.com/article/10.1007/s12185-017-2338-6
*  Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma - Study Results - ClinicalTrials.gov
Anaplastic Large Cell Lymphoma. Angioimmunoblastic T-cell Lymphoma. Extranodal Marginal Zone B-cell Lymphoma of Mucosa- ... associated Lymphoid Tissue. Nodal Marginal Zone B-cell Lymphoma. Recurrent Adult Diffuse Large Cell Lymphoma. Recurrent Adult ... Pharmacodynamic Effects of Flavopiridol on Normal Peripheral Blood Mononuclear Cells (PBMCs). [ Time Frame: Day 1 ]. ... Recurrent Adult Hodgkin Lymphoma. Recurrent Adult T-cell Leukemia/Lymphoma. Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma. ...
  https://clinicaltrials.gov/ct2/show/results/NCT00112723
*  ALK+ large B-cell lymphoma - Wikipedia
... aggressive large B-cell process that shows ALK expression. It is distinct from anaplastic large cell lymphoma, a T-cell ... Morphologically, there are large immunoblast-like cells with large central nucleoli, often cellular clusters, with a ... WHO classification of tumours of haematopoietic and lymphoid tissues. World Health Organization classification of tumours. 2 ( ... "Anaplastic lymphoma kinase-positive large B-cell lymphoma: an underrecognized aggressive lymphoma". Adv Hematol. 2012: 529572. ...
  https://en.wikipedia.org/wiki/ALK+_large_B-cell_lymphoma
*  CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody - Without BSA and Azide
... , Mouse Monoclonal Antibody [Clone Ki-1/ ... This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas ... It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of ... derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas ...
  http://www.abgent.com/products/AH12693-CD30--TNFRSF8-Hodgkin-Reed-Sternberg-Cell-Marker-Antibody-Without-BSA-and-Azide
*  CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody - Mouse Monoclonal Antibody [Clone SPM121 ] IHC, IF, FC - Buy...
CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody, Mouse Monoclonal Antibody [Clone SPM121 ] validated in IHC, IF ... This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas ... It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of ... derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas ...
  http://www.abgent.com/products/AH12690-CD30--TNFRSF8-Hodgkin-Reed-Sternberg-Cell-Marker-Antibody
*  Single-Fraction Radiotherapy for CD30+ Lymphoproliferative Disorders
... or nodal anaplastic large-cell lymphoma and Hodgkin's Lymphoma [3, 6, 7]. It has been described that LYP, Hodgkin's Lymphoma, ... Similar to LYP, CD30+ expression is seen in ,75% of CALCL cells, which have a large anaplastic, pleomorphic appearance [2]. ... lymphoma, melanoma, or carcinoma) and the increased incidence of secondary lymphoid neoplasms in LYP patients have led to ... J. B. Yu, J. M. McNiff, M. W. Lund, and L. D. Wilson, "Treatment of primary cutaneous CD30+ anaplastic large cell lymphoma with ...
  https://www.hindawi.com/journals/bmri/2015/629587/
*  3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma - Full Text View - ClinicalTrials.gov
Cutaneous T-cell Lymphoma Burkitt Lymphoma Mycosis Fungoides Lymphoma, Large-cell Anaplastic Large Cell Lymphoma Sezary ... Angioimmunoblastic T-cell Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Intraocular ... 3-AP may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. ... B-cell, Chronic B-cell Lymphoma Mantle Cell Lymphoma Diffuse Large B-Cell Lymphoma Hodgkin Lymphoma Marginal Zone Lymphoma ...
  https://clinicaltrials.gov/ct2/show/NCT00293345?recr=Open&cond=%22Lymphoma%2C+Non-Hodgkin%22&rank=16
*  Lenalidomide Maintenance Therapy After High Dose BEAM With or Without Rituximab - Full Text View - ClinicalTrials.gov
Lymphoma, Large-cell Anaplastic Large Cell Lymphoma Sezary Syndrome Lymphoblastic Lymphoma Extranodal Nasal NK/T Cell Lymphoma ... Angioimmunoblastic T-cell Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Nodal Marginal ... Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing ... Peripheral T-cell Lymphoma Follicular Lymphoma B-cell Lymphoma Mantle Cell Lymphoma Diffuse Large B-Cell Lymphoma Marginal Zone ...
  https://clinicaltrials.gov/ct2/show/NCT01035463?cond=%22Lymphoma%2C+Non-Hodgkin%22&rank=15
*  Tanespimycin and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas - Full Text View - ClinicalTrials.gov
Cutaneous T-cell Lymphoma Waldenstrom Macroglobulinemia Lymphoma, Large-cell Anaplastic Large Cell Lymphoma Sezary Syndrome ... Angioimmunoblastic T-cell Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Nodal Marginal ... in peripheral blood mononuclear cells and tumor specimens from patients with advanced solid tumors or lymphomas (Accrual for ... Hodgkin Lymphoma Follicular Lymphoma B-cell Lymphoma Mantle Cell Lymphoma Diffuse Large B-Cell Lymphoma Marginal Zone Lymphoma ...
  https://clinicaltrials.gov/ct2/show/study/NCT00096005?view=record
*  Tanespimycin and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas - Full Text View - ClinicalTrials.gov
T-cell, Chronic Adult T-cell Leukemia/lymphoma Lymphoma, Large-cell Anaplastic Large Cell Lymphoma Lymphoblastic Lymphoma ... Angioimmunoblastic T-cell Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Nodal Marginal ... in peripheral blood mononuclear cells and tumor specimens from patients with advanced solid tumors or lymphomas (Accrual for ... Lymphoma, Large B-Cell, Diffuse. Burkitt Lymphoma. Lymphoma, T-Cell. Lymphoma, Large-Cell, Immunoblastic. Plasmablastic ...
  https://clinicaltrials.gov/ct2/show/study/NCT00096005?view=results
*  Cilengitide (EMD 121974) in Treating Patients With Advanced Solid Tumors or Lymphoma - Full Text View - ClinicalTrials.gov
Lymphoma, T-Cell, Cutaneous. Leukemia, T-Cell. Leukemia-Lymphoma, Adult T-Cell. Lymphoma, Large-Cell, Anaplastic. Immunoblastic ... Angioimmunoblastic T-cell Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Intraocular ... Cilengitide (EMD 121974) may stop the growth of cancer cells by stopping blood flow to the cancer ... Precursor Cell Lymphoblastic Leukemia-Lymphoma. Lymphoma, Large B-Cell, Diffuse. Burkitt Lymphoma. Lymphoma, T-Cell. Lymphoma, ...
  https://clinicaltrials.gov/show/NCT00077155?order=183
*  Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body...
Stage I Adult T-cell Leukemia/Lymphoma Stage I Childhood Anaplastic Large Cell Lymphoma Stage I Childhood Large Cell Lymphoma ... Leukemia, Lymphoid. Precursor Cell Lymphoblastic Leukemia-Lymphoma. Leukemia, Lymphocytic, Chronic, B-Cell. Lymphoma, B-Cell. ... The donated stem cells may replace the patient's immune system and help destroy any remaining cancer cells (graft-versus-tumor ... Lymphoma, B-Cell, Marginal Zone. Lymphoma, Large B-Cell, Diffuse. Burkitt Lymphoma. Lymphoma, T-Cell. Lymphoma, Large-Cell, ...
  https://clinicaltrials.gov/ct2/show/NCT00089011?recr=Open&cond=%22Mycoses%22&rank=3