Comprehensive vaccine design for commensal disease progression | Science Advances
On ice, the background liposome solution was passed twice through a filter with 50-nm pore size and replaced each time with PBS ... Next, proteins were incubated with liposomes for 30 min at 4°C with surface attachment mediated via polyhistidine tag-Ni ... Lipids were then rehydrated with phosphate-buffered saline (PBS) containing the polysaccharide antigens to form liposomes, ... were added to 50 μl of liposome solution, followed by incubation at 80°C for 30 min and 22°C for 30 min before colorimetric ...http://advances.sciencemag.org/content/3/10/e1701797.full
Effects of phosphatidylserine and cholesterol liposomes on the viability, motility, and acrosomal integrity of stallion...
Spermatozoa were pretreated with: (1) Hepes-buffered medium (SHB); (2) phosphatidylserine (PS) liposomes; or (3) liposomes ... but were not affected by PSCH liposome treatment (P , 0.05). Addition of PSCH liposomes improved recovery of motile spermatozoa ... In Experiment 2, motion parameters were compared for spermatozoa pretreated with PSCH liposomes and cryopreserved in either ... PSCH liposome-treated samples had higher percentages of motile spermatozoa than untreated samples regardless of freezing ...https://www.semanticscholar.org/paper/Effects-of-phosphatidylserine-and-cholesterol-lipo-Wilhelm-Graham/24169b0af8e01a38d59edd0b46fe88fab25e8999
Fick's second law transformed: one path to cloaking in mass diffusion | Journal of The Royal Society Interface
One popular type of liposomes, known as the stealth liposomes , are highly stable, long-circulating liposomes whereby ... Potential fabrication of this alternative liposome would involve additional procedures to the classical liposome fabrication ... 2003 Lateral diffusion rates of lipid, water, and a hydrophobic drug in a multilamellar liposome. Biophys. J. 85, 1734-1740. ... 2007 Lipid-based colloidal carriers for peptide and protein delivery: liposomes versus lipid nanoparticles. Int. J. Nanomed. 2 ...http://rsif.royalsocietypublishing.org/content/10/83/20130106
Influence of poly(ethylene glycol) grafting density and polymer length on liposomes : Relating plasma circulation lifetimes to...
... liposome-liposome aggregation and pharmacokinetics in mice. Cholesterol-free liposomes were chosen because of their increasing ... particularly liposome-liposome aggregation.. Place, publisher, year, edition, pages. 2007. Vol. 1768, no 6, 1367-1377 p. ... Specifically, liposomes containing various molecular weight PEG-lipids at a variety of molar proportions were analyzed for in ... The purpose of the studies described here was to compare the effects of PEG-lipid incorporation in liposomes on protein binding ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:38872
Compared with conventional liposomes, sterically stabilized liposomes have a 100-fold increase in AUC (3) . However, for the ... between tumor liposome uptake and plasma liposome AUC is linear for both conventional and sterically stabilized liposomes (11) ... Lessons from conventional liposomes Lasic D. D. Papahadjopoulos D. eds. . Medical Applications of Liposomes, : 231-257, ... showed that DSPC/cholesterol liposomes had a 2-fold Te of PEGylated liposome when given at the maximal tolerated dose of 55 mg/ ...http://clincancerres.aacrjournals.org/content/5/11/3645
Focused Ultrasound Hyperthermia Mediated Drug Delivery Using Thermosensitive Liposomes and Visualized With in vivo Two-Photon...
Polymer-grafted liposomes: physical basis for the "stealth" property. J Liposome Res. 1992;2:411-30 ... Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors. Pharm Res. 2010;27: ... A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft ... Dou Y, Hynynen K, Allen C. To heat or not to heat: Challenges with clinical translation of thermosensitive liposomes. J ...http://thno.org/v07p2718.htm
Fluorescent Liposomes - Fluorescent Liposomes (Encapsulated dyes) - FormuMax Scientific, Inc.
Fluorescent Liposomes (Encapsulated dyes). Soluble fluorescent dyes are encapsualted inside liposomes. The free external dye is ...http://www.liposomeexpert.com/categories/fluorescent-liposomes/fluorescent-liposomes-encapsulated-dyes.html
Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
We demonstrate that the liposome-based vaccine elicited, rapidly and robustly, specific antisera in wild-type mice and in Tau. ... Here we adapted the liposome-based amyloid vaccine that proved safe and efficacious, and incorporated a synthetic ... The data corroborate the hypothesis that liposomes carrying phosphorylated peptides of protein Tau have considerable potential ...http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072301
Evaluation of the high-pressure extrusion technique as a method for sizing plasmid DNA-containing cationic liposomes | Drug...
This is a well-known sizing method for liposomes, but so far, it has not been applied for liposomes that are already loaded ... J Liposome Res, Volume 21, Issue 4, pp. 286-295 (2011). ISBN:. 1532-2394 (Electronic)08 DOI Name (links to online publication) ... Liposomes composed of egg PC, DOTAP, and DOPE with entrapped pDNA were prepared by the dehydration-rehydration method and ... In addition, these liposomes were able to stimulate Toll-like receptor 9, indicating efficient endosomal uptake and release of ...http://drugdeliverytechnology.leidenuniv.nl/publications/3283
Wiring liposomes and chloroplasts to the grid with an electronic polymer.
... Jullesson, David Linköping University, Department of ... The liposomes allow for a more controllable and easily manipulated system compared to the thylakoid membrane. In the model ... A liposomal model system based on liposomes formed by oleic acid was used to develop and study the incorporation of PEDOT-S to ...http://www.diva-portal.org/smash/record.jsf?pid=diva2:648164
U.S. Patent: 5532001 - Stimulation of tanning by DNA fragments or single-stranded DNA - July 2, 1996
CTRL=control (no liposomes or DNA fragments); A1=empty liposomes (no DNA fragments); B1=liposomes containing UV-DNA (irradiated ... mu.M empty liposomes (A.sub.1); 100 .mu.M liposomes containing UV-DNA (irradiated) (B.sub.1); and 100 .mu.M liposomes ... mu.M empty liposomes (A.sub.1); 100 .mu.M liposomes containing UV-DNA (irradiated) (B.sub.1); 100 .mu.M liposomes containing ... empty liposomes (no DNA fragments); B1=liposomes containing UV-DNA (irradiated); C1=liposomes containing DNA (not irradiated). ...http://www.everypatent.com/comp/pat5532001.html
Molecular Dynamics Studies of Liposomes as Carriers for Photosensitizing Drugs : Development, Validation, and Simulations with...
Liposomes are proposed as drug delivery systems and can in principle be designed so as to cohere with specific tissue types or ... Liposomes with 21-84 hypericin molecules were generated and subjected to 10 microsecond simulations. Distribution of the ... In the current work, a coarse-grained (CG) liposome model is developed, consisting of over 2500 lipids, with varying degrees of ... Molecular Dynamics Studies of Liposomes as Carriers for Photosensitizing Drugs: Development, Validation, and Simulations with a ...http://su.diva-portal.org/smash/record.jsf?pid=diva2:699656
The liposomes were diluted in HBSS and 0.1% BSA to a final volume of 35 ml. Downsizing of the liposomes to form SUVs (mean ... and myelotoxicity with liposome-based therapy. The fact that myelosuppression was found to be less severe in liposome-treated ... biodistribution and therapeutic efficacy of doxorubicin encapsulated in Stealth liposomes (Doxil). J. Liposome Res., 4: 667-687 ... To improve the therapeutic index of IL-2, Kedar et al. (18, 19, 20) have used liposomes aimed at improving the cytokine ...http://clincancerres.aacrjournals.org/content/5/3/687
Endocytosis of liposomes bound to cell surface proteins measured by flow cytofluorometry | Biochemical Journal
Endocytosis of liposomes bound to cell surface proteins measured by flow cytofluorometry. A Truneh, Z Mishal, J Barbet, P Machy ... Endocytosis of liposomes bound to cell surface proteins measured by flow cytofluorometry ... Endocytosis of liposomes bound to cell surface proteins measured by flow cytofluorometry ... Binding and internalization of such liposomes by cells via antibodies directed towards membrane surface determinants results in ...http://www.biochemj.org/content/214/1/189
What are liposomes? | Reference.com
Liposomes are used in drug delivery, including vaccines. They prevent healthy cells from receiving the drug and prevent the ... A liposome is a vesicle with walls made of phospholipids. ... A liposome is a vesicle with walls made of phospholipids. ... Liposomes were first discovered in England by Alec C. Bangham in 1961. He found that when phospholipids were combined with ... Liposomes are used in drug delivery, including vaccines. They prevent healthy cells from receiving the drug and prevent the ...https://www.reference.com/science/liposomes-3c350733378a6f8c
GAS-CONTAINING LIPOSOMES - NORTHWESTERN UNIVERSITY
In particular, the present invention provide methods of generating gas-containing liposomes where the gas is introduced under ... liposomes with gas, to generate a gas-liposome dispersion; and thawing said gas-liposome dispersion to generate a plurality of ... liposomes with gas, to generate a gas-liposome dispersion; and thawing said gas-liposome dispersion to generate a plurality of ... wherein the liposomes comprise nitric oxide gas. In certain embodiments, the liposomes the liposomes comprise at least 5 ul, at ...http://www.freepatentsonline.com/y2008/0175893.html
Chemicals, Functional / Liposomes - HAPPI
Liposomes - HAPPI is the industry's leading magazine covering the global personal care, household and industrial and ...http://www.happi.com/buyersguide/chemicals-functional/liposomes/
Liposome - Wikipedia
Liposomes are used as models for artificial cells. Liposomes can also be designed to deliver drugs in other ways. Liposomes ... A liposome is a spherical vesicle having at least one lipid bilayer. The liposome can be used as a vehicle for administration ... Liposomes can also be decorated with opsonins and ligands to activate endocytosis in other cell types. The use of liposomes for ... Another strategy for liposome drug delivery is to target endocytosis events. Liposomes can be made in a particular size range ...https://en.wikipedia.org/wiki/Liposome
Jar Deconstructed: Liposomes
Liposomes are frequently utilized to deliver key actives, with hyaluronic acid winning the award for most popular and hydration ... In it, liposomes deliver essential moisture to the skin.. Finally, Osmosis coats its ingredients with a liposome called ... Liposomes are tiny delivery vehicles that transport ingredients into the skin. Made from lipids, liposomes simulate skin's ... Some liposomes, e.g., Transfersomes and deformable liposomes, appear to penetrate fully intact into skin. ...https://www.skininc.com/skinscience/physiology/Jar-Deconstructed-Liposomes-463913473.html
Cationic liposome - Wikipedia
Cationic liposomes are structures that are made of positively charged lipids and are increasingly being researched for use in ... They are also able to interact with negatively charged cell membranes more readily than classical liposomes. Fusion between ... Upon interacting with negatively charged DNA, cationic liposomes form clusters of aggregated vesicles. At a critical density ... This process bypasses the endosomal-lysosomal route which leads to degradation of anionic liposome formulations. Cationic ...https://en.wikipedia.org/wiki/Cationic_liposome
Unilamellar liposome - Wikipedia
Small unilamellar liposomes/vesicles (SUVs) have sizes up to 100 nm; large unilamellar liposomes/vesicles (LUVs) may have sizes ... Unilamellar liposome is a spherical chamber/vesicle, bounded by a single bilayer of an amphiphilic lipid or a mixture of such ... Phospholipid liposomes are used as targeted drug delivery systems. Hydrophilic drugs can be carried as solution inside the SUVs ... In contrast, multilamellar liposomes (MLVs), consist of many concentric amphiphilic lipid bilayers analogous to onion layers, ...https://en.wikipedia.org/wiki/Unilamellar_liposome
Liposomes as a Drug Delivery System: Optimization Studies | SpringerLink
The great structural versatility of liposomes, their relatively inoccuous nature and ability to incorporate a wide spectrum of ... Y.E. Rahman, Liposomes and chelating agents, in: "Liposomes in Biological Systems", G. Gregoriadis, ed., John Wiley, Chichester ... G. Gregoriadis, Liposomes as carriers for drugs and vaccines, Trends in Biotechnology, 3:235 (1985)CrossRefGoogle Scholar ... B. Wolff and G. Gregoriadis, The use of monoclonal anti-Thy1 IgG1 for the targeting of liposomes to AKR-A cells in vitro and in ...https://link.springer.com/chapter/10.1007/978-1-4684-7908-9_12
Structure and Function of Trypsin-Loaded Fibrinolytic Liposomes
... Anna Tanka-Salamon,1 Attila Bóta,2 András Wacha,2 Judith ... V. Saxena, C. G. Johnson, A. H. Negussie, K. V. Sharma, M. R. Dreher, and B. J. Wood, "Temperature-sensitive liposome-mediated ... conjugated thermosensitive liposomes (HER2 + affisomes)," Journal of Controlled Release, vol. 153, no. 2, pp. 187-194, 2011. ...https://www.hindawi.com/journals/bmri/2017/5130495/ref/
Phys.org - liposomes(... continued page 2)
Liposome. Liposomes are artificially prepared vesicles made of lipid bilayer. Liposomes can be filled with drugs, and used to ... Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, ... Researchers COMMAND a Better Class of Liposomes. (PhysOrg.com) -- Pop a bubble while washing the dishes and you're likely to ... Researchers show once and for all that liposomes cannot function as carriers transporting active agents into the skin. Many ...https://phys.org/tags/liposomes/sort/rank/all/page2.html
Journal of Liposome Research - Wikipedia
The Journal of Liposome Research is a peer-reviewed academic journal that publishes original research on the topics of ... liposomes and related systems, lipid-based delivery systems, lipid biology, and both synthetic and physical lipid chemistry. ... the general scope of the journal and abstracts and conference proceedings including those from the International Liposome ...https://en.wikipedia.org/wiki/Journal_of_Liposome_Research