*  Genome-Wide Association Study of Intracranial Aneurysms Confirms Role of Anril and SOX17 in Disease Risk | Stroke
The linkage disequilibrium structure of the chromosome 9p21 region has at least 2 major linkage disequilibrium blocks. The ... The color of the square symbol denotes the extent of linkage disequilibrium (as computed by r2) with the SNP reported in the ... 4 The SNP in the 2 regions were not in linkage disequilibrium and appear to have independent effects. The association with both ... located in intron 12 of CDKN2BAS and having limited linkage disequilibrium spanning introns 7 through 15 of CDKN2BAS. The ...
  http://stroke.ahajournals.org/content/43/11/2846.long
*  "Efficient mining of haplotype patterns for linkage disequilibrium mapp" by Lin L., Wong L. et al.
Linkage disequilibrium mapping is the process of finding disease gene locations through comparisons of haplotype frequencies ... Therefore, it is useful for linkage disequilibrium mapping when the users do not have such information about their datasets. © ... This work presents a new method for linkage disequilibrium mapping. The main advantage of the proposed algorithm, called ... We compared our method with some leading methods in linkage disequilibrium mapping such as HapMiner, Blade, GeneRecon, and ...
  http://ink.library.smu.edu.sg/sis_research/3016/
*  Plus it
Based on the genotypes of the 24 Pima Indians, SNP 1 appeared to be in complete linkage disequilibrium with SNP 2. SNP 6 was a ... 0.93 for the more common allele, respectively). However, in Pima Indians, the two SNPs are in high linkage disequilibrium and ... In Pima Indians, this promoter polymorphism is in strong linkage disequilibrium with the Pro12Ala variant; therefore, the ... these two SNPs were in high linkage disequilibrium (,D′, = 0.98) in Pima Indians. To assess whether either of these PPARγ2 SNPs ...
  http://diabetes.diabetesjournals.org/content/52/7/1864
*  Genome-wide SNP analysis reveals no gain in power for association studies of common variants in the Finnish Saami
Theoretical work has indicated that under this demographic scenario, extensive linkage disequilibrium (LD) is generated by ... Saami; genome-wide association studies; linkage disequilibrium; population isolates National Category Otorhinolaryngology ...
  http://liu.diva-portal.org/smash/record.jsf?pid=diva2:666273
*  Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis
... within the MHC for the majority of these diseases has remained difficult due to the great variability and extensive linkage ... disequilibrium (LD) that exists among alleles throughout this locus, coupled with inadequate study design whereby only a ... Griffiths2005A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of ... 2005) A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag ...
  http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1000024
*  Ancestry-informative marker - Wikipedia
... novel genes underlying complex diseases in a technique called admixture mapping or mapping by admixture linkage disequilibrium ...
  https://en.wikipedia.org/wiki/Ancestry-informative_marker
*  Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease | Gut
Linkage disequilibrium (D′) between variants was calculated by the ldmax algorithm implemented in the GOLD software package.17 ... Strong linkage disequilibrium between variants from the 5′ and 3′ extremes of the IBD5 haplotype (IGR2060a_1 and IGR3096a_1) ... Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum ... However, the presence of strong linkage disequilibrium means the genetic approach alone has so far been unable to pinpoint the ...
  http://gut.bmj.com/content/52/4/541
*  Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. - Oxford Neuroscience
We now present follow-up linkage disequilibrium mapping of the linked region utilizing 3,047 single nucleotide polymorphism ( ... by performing a meta-analysis of original genotype data from 11 genome scan linkage studies. ... We previously reported genome-wide significant evidence for linkage between chromosome 6q and bipolar I disorder (BPI) ... Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. ...
  https://www.neuroscience.ox.ac.uk/publications/168301
*  "MCP-1-MCP-3-Eotaxin Gene Cluster Influences HIV-1 Transmission" by William Modi, James J. Goedert et al.
Conclusions: Although the extensive linkage disequilibrium precludes positive identification of the causal variant, the results ... Results: Extensive linkage disequilibrium was observed. Three SNP (−2136T located in theMCP-1 promoter region, 767G in intron 1 ... Results: Extensive linkage disequilibrium was observed. Three SNP (−2136T located in theMCP-1 promoter region, 767G in intron 1 ... Conclusions: Although the extensive linkage disequilibrium precludes positive identification of the causal variant, the results ...
  http://nsuworks.nova.edu/cnso_bio_facarticles/626/
*  CRAN - Package dartR
Advanced filtering is based on Linkage Disequilibrium and HWE. Other functions are available for visualization after PCoA, or ...
  https://cran.ncc.metu.edu.tr/web/packages/dartR/index.html
*  Linkage disequilibrium between four intragenic polymorphic microsatellites of the NF1 gene and its implications for genetic...
Linkage disequilibrium between four intragenic polymorphic microsatellites of the NF1 gene and its implications for genetic ... Linkage disequilibrium between four intragenic polymorphic microsatellites of the NF1 gene and its implications for genetic ... Because of linkage disequilibrium, the informativeness of marker combinations for genotyping of NF1 families is diminished. ... Three of these markers, AAAT Alu repeat, ACI27.2, and IVS38GT53.0, exhibit linkage disequilibrium between each other. Analysis ...
  http://jmg.bmj.com/content/33/7/590
*  Variation summary | EMBL-EBI Train online
Find out which alleles are carried by individuals Linkage disequilibrium. View LD plots and export values Phenotype data. See ... Click on any link or icon to go to information such as population genetics, linkage disequilibrium, or phenotypes and diseases ...
  https://www.ebi.ac.uk/training/online/course/ensembl-browsing-chordate-genomes/navigating-ensembl/investigating-sequence-variation/varia-1
*  Multiple loci on 8q24 associated with prostate cancer susceptibility. - Oxford Clinical Trials Research Unit
Eight SNPs in five linkage disequilibrium blocks were independently associated with prostate cancer susceptibility. ... We confirmed associations at three previously reported loci and identified additional loci in two other linkage disequilibrium ... We confirmed associations at three previously reported loci and identified additional loci in two other linkage disequilibrium ... Eight SNPs in five linkage disequilibrium blocks were independently associated with prostate cancer susceptibility. ...
  https://www.octru.ox.ac.uk/publications/107751
*  Contributions of linkage disequilibrium and co-segregation information to the accuracy of genomic prediction | Genetics...
12711_2016_255_MOESM1_ESM.pdf Additional file 1. Boundaries of linkage disequilibrium between a QTL and a SNP with different ... Qanbari S, Pimentel E, Tetens J, Thaller G, Lichtner P, Sharifi A, Simianer H. The pattern of linkage disequilibrium in German ... Minor allele frequencies (MAF) of QTL and SNPs and the level of historical linkage disequilibrium (LD) in the base population ... de Roos A, Hayes B, Spelman R, Goddard M. Linkage disequilibrium and persistence of phase in Holstein-Friesian. Jersey and ...
  https://gsejournal.biomedcentral.com/articles/10.1186/s12711-016-0255-4
*  Investigation of recombination hotspots and blocks of linkage disequilibrium within the human PGM1 gene - UCL Discovery
Investigation of recombination hotspots and blocks of linkage disequilibrium within the human PGM1 gene. The American Journal ... Investigation of recombination hotspots and blocks of linkage disequilibrium within the human PGM1 gene ... Investigation of recombination hotspots and blocks of linkage disequilibrium within the human PGM1 gene. ...
  http://discovery.ucl.ac.uk/182204/
*  Transmission disequilibrium test - Wikipedia
McGinnis RE, Ewens WJ, Spielman RS (1995). "The TDT reveals linkage and linkage disequilibrium in a rare disease". Genet ... Spielman RS, Ewens WJ (Nov 1996). "The TDT and other family-based tests for linkage disequilibrium and association". Am J Hum ... Beagle Spielman RS, McGinnis RE, Ewens WJ (Mar 1993). "Transmission test for linkage disequilibrium: the insulin gene region ... The transmission disequilibrium test (TDT) was proposed by Spielman, McGinnis and Ewens (1993) as a family-based association ...
  https://en.wikipedia.org/wiki/Transmission_disequilibrium_test
*  Linkage disequilibrium questions
... Francesco Zito ZITO at CMNS.MNEGRI.IT Tue Jul 11 08:47:52 EST 1995 *Previous message: ... more or less in linkage disequilibrium. Why the concept of genetic 'co-segregation' is so closely connected to linkage ... Which are the mathematical basis of the 'linkage disequilibrium'? Which are the parameters considered in the analysis? I don't ... had been verified to be in strong linkage disequilibrium; in my data, anyway, one of them is present in a different frequency ...
  http://www.bio.net/bionet/mm/gen-link/1995-July/000762.html
*  LINKAGE DISEQUILIBRIUM IN ISOLATED POPULATIONS OF DROSOPHILA MELANOGASTER | Genetics
LINKAGE DISEQUILIBRIUM IN ISOLATED POPULATIONS OF DROSOPHILA MELANOGASTER Message Subject (Your Name) has forwarded a page to ... LINKAGE DISEQUILIBRIUM IN ISOLATED POPULATIONS OF DROSOPHILA MELANOGASTER. Osamu Yamaguchi, Motoshi Ichinose, Muneo Matsuda and ... LINKAGE DISEQUILIBRIUM IN ISOLATED POPULATIONS OF DROSOPHILA MELANOGASTER. Osamu Yamaguchi, Motoshi Ichinose, Muneo Matsuda and ... LINKAGE DISEQUILIBRIUM IN ISOLATED POPULATIONS OF DROSOPHILA MELANOGASTER. Osamu Yamaguchi, Motoshi Ichinose, Muneo Matsuda and ...
  http://www.genetics.org/content/96/2/507
*  Simultaneous Detection of Linkage Disequilibrium and Genetic Differentiation of Subdivided Populations | Genetics
The method detected linkage disequilibrium and estimated linkage disequilibrium coefficient and FST correctly. ... affect linkage disequilibrium. Therefore, when assessing linkage disequilibrium in natural populations, it is very important to ... Wu, R., and Z-B. Zeng, 2001 Joint linkage and linkage disequilibrium mapping in natural populations. Genetics 157: 899-909. ... Xiong, M. M., and S. W. Guo, 1997 Fine-linkage genetic mapping based on linkage disequilibrium theory and applications. Am. J. ...
  http://www.genetics.org/content/167/4/2003
*  Linkage Disequilibrium and Persistence of Phase in Holstein-Friesian, Jersey and Angus Cattle | Genetics
Linkage Disequilibrium and Persistence of Phase in Holstein-Friesian, Jersey and Angus Cattle. A. P. W. de Roos, B. J. Hayes, R ... Linkage Disequilibrium and Persistence of Phase in Holstein-Friesian, Jersey and Angus Cattle. A. P. W. de Roos, B. J. Hayes, R ... Linkage Disequilibrium and Persistence of Phase in Holstein-Friesian, Jersey and Angus Cattle. A. P. W. de Roos, B. J. Hayes, R ... Linkage Disequilibrium and Persistence of Phase in Holstein-Friesian, Jersey and Angus Cattle ...
  http://www.genetics.org/content/179/3/1503
*  Experimental Designs for Reliable Detection of Linkage Disequilibrium in Unstructured Random Population Association Studies |...
Associations occur because of linkage disequilibrium between the marker and trait. "Linkage disequilibrium (LD) mapping" aims ... the hypothesis of no linkage disequilibrium) and H1 (e.g., the hypothesis of a nonzero QTL effect in linkage disequilibrium ... reviewing prospects for whole-genome linkage disequilibrium mapping, suggests that the useful range of linkage disequilibrium ... of linkage disequilibrium between a biallelic QTL and a biallelic marker with given posterior odds for linkage disequilibrium ...
  http://www.genetics.org/content/170/2/859.full
*  Linkage disequilibrium - Wikipedia
The level of linkage disequilibrium between A and B can be quantified by the coefficient of linkage disequilibrium D A B {\ ... The coefficient of linkage disequilibrium D {\displaystyle D} is not always a convenient measure of linkage disequilibrium ... Other pairs of alleles at those same two loci may have different coefficients of linkage disequilibrium. Linkage disequilibrium ... a sizable fraction of alleles are in linkage disequilibrium. An example of such linkage disequilibrium is between HLA-A1 and B8 ...
  https://en.wikipedia.org/wiki/Linkage_disequilibrium
*  Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium
... we will employ Mapping by Admixture Linkage Disequilibrium (MALD). analysis, a specialized form of linkage disequilibrium ... identify chromosomal loci that are in admixture linkage disequilibrium with:. - ESRD in a case-control design. - ESRD ... Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium. Trial Phase ... Americans contain marker alleles that are in admixture linkage disequilibrium with ESRD. susceptibility alleles.. Objectives:. ...
  http://www.knowcancer.com/cancer-trials/NCT00559767/
*  Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium | Journal of The Royal Society...
Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium Message Subject (Your Name) has ... Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium. Victor Garcia, Emily C. Glassberg ... Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium. Victor Garcia, Emily C. Glassberg ... Here, we explore how these evolutionary dynamics are mirrored in multilocus linkage disequilibrium (MLD), a measure of multi- ...
  http://rsif.royalsocietypublishing.org/content/15/140/20170921