*  Bioprinting: The Kidney's Proximal Tubules
The Kidney's Proximal Tubules on Wyss Institute , In this video, see how the Wyss Institute team has advanced bioprinting to ... how the Wyss Institute team has advanced bioprinting to the point of being able to fabricate a functional subunit of a kidney. ...
  https://wyss.harvard.edu/media-post/bioprinting-the-kidneys-proximal-tubules/?q=Organ%20Engineering
*  Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28. | JCB
Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28.. R Zhang ... These results indicate that CHIP28k is a major and highly selective water transporting protein in the kidney proximal tubule ... Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28. ... antisense probe to tissue sections from rat kidney showed selective CHIP28k localization to epithelial cells in proximal tubule ...
  http://jcb.rupress.org/content/120/2/359
*  Dexamethasone - Phenotypes | CTD
Kidney Tubules, Proximal , Cell Line, Transformed. 1. 49.. Dexamethasone positive regulation of blood coagulation F3 , ...
  http://ctd.mdibl.org/detail.go?type=chem&acc=D003907&view=phenotype
*  Oxidation of Fatty Acids Is the Source of Increased Mitochondrial Reactive Oxygen Species Production in Kidney Cortical Tubules...
Because more than 90% of kidney cortex consists of proximal tubules, our results can be attributed to proximal tubule ... Proximal kidney tubules (,90% of the kidney cortex) rely on FA rather than glucose to form ATP during normal metabolic ... Substrate processing rather than the mitochondrial ETC is changed in kidney tubules in diabetes.. Diabetic tubule kidney ... CPT1 in kidney cortical tubule mitochondria. A: Specific activity of CPT1 in tubule mitochondria from control and diabetic ...
  http://diabetes.diabetesjournals.org/content/61/8/2074
*  Active transport of organic acids in the proximal tubules of the surviving rat kidney normally and under various influences. II...
... into the rat renal proximal tubules at 20 degrees C. Carbacholine decreasing intracellular cAMP concentration stimulated the ... Active transport of organic acids in the proximal tubules of the surviving rat kidney normally and under various influences. II ... article{Bresler1979ActiveTO, title={[Active transport of organic acids in the proximal tubules of the surviving rat kidney ... into the rat renal proximal tubules at 20 degrees C. Carbacholine decreasing intracellular cAMP concentration stimulated the ...
  https://www.semanticscholar.org/paper/Active-transport-of-organic-acids-in-the-proximal-Bresler-Nikiforov/82da9eb4db80275848290416cd35bdcea6db2843
*  Proximal tubule Kim-1 expression modulates acute and chronic kidney injury - Craig Brooks
... are vital to the function of the kidney and are also integral to the pathology of the injured kidney. They are the... ... Kidney proximal tubule cells are the most sensitive cells in the kidney to ischemic and nephrotoxic insults. This study will ... Proximal tubule Kim-1 expression modulates acute and chronic kidney injury Brooks, Craig Robert Brigham and Women's Hospital, ... Renal proximal tubule epithelial cells (PTCs) are vital to the function of the kidney and are also integral to the pathology of ...
  http://grantome.com/grant/NIH/K01-DK099473-01
*  Effect of SCM on albumin-induced changes of staining pa | Open-i
Kidney Tubules, Proximal/cytology/drug effects/metabolism. *Microscopy, Fluorescence. *NF-kappa B/metabolism ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4401473_nihms675730f4&req=4
*  Meprin β deficiency associated with higher levels of neutrophil gelatinase associated lipocalin (NGAL) and kidney injury...
Meprins are metalloproteinases which are most abundantly expressed in the brush border membranes of proximal kidney tubules. ... Meprins are metalloproteinases which are most abundantly expressed in the brush border membranes of proximal kidney tubules. ... Further analysis will determine the kidney meprin targets and metabolic pathways which play a role in the progression of DN. ... Taken together, the data suggest that presence of meprin β partially protects mice from the tubular kidney injury associated ...
  https://www.rti.org/publication/meprin-%CE%B2-deficiency-associated-higher-levels-neutrophil-gelatinase-associated-lipocalin
*  Kidney tubule, TEM - Stock Image P550/0208 - Science Photo Library
... of a section through a proximal convoluted tubule in the kidney. The proximal convoluted tubules function to reabsorb water, ... The tubules consist of a lumen (interior, white) lined with cuboidal epithelial cells (green). These cells are covered in many ... The reabsorbed molecules move into the interstitial fluid of the kidney and are absorbed back into the blood. The liquid in the ... tubules passes to the bladder. - Stock Image P550/0208 ... of a section through a proximal convoluted tubule in the kidney ...
  http://www.sciencephoto.com/media/310651/view/kidney-tubule-tem
*  Plus it
K-ATPase is a target of TGF-β1 signaling in proximal tubule kidney epithelial cells. LLC-PK1 cells, a porcine proximal tubule- ... Staining shows reduced NaK-β1 and NaK-α1 staining in kidney tubules of streptozotocin-induced rats compared with normal kidney ... We show that following the treatment of renal proximal tubule cells with TGF-β1, NaK-β1 surface expression is reduced before ... Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells. Curr Opin Nephrol Hypertens 2003;12: ...
  http://mct.aacrjournals.org/content/9/6/1515
*  Produktübersicht 50 Prolactin Receptor Proteine
Prolactin receptor was upregulated in proximal kidney tubule cells of mice with cardiac disease. ... a residue quartet in the extracellular membrane proximal domain of the homodimeric cytokine receptor (zeige EBI3 Proteine) ...
  http://www.antikoerper-online.de/jak-stat-signalweg-pathway-6/prolactin-receptor-protein-33641/
*  "Loss of NHERF-1 Expression Prevents Dopamine-Mediated Na-K-ATPase Regu" by Michelle T Barati, Corey J Ketchem et al.
Kidney Tubules, Proximal; Male; Phosphoproteins; Rats; Rats, Inbred SHR; Signal Transduction; Sodium-Hydrogen Antiporter; ... Loss of NHERF-1 Expression Prevents Dopamine-Mediated Na-K-ATPase Regulation in Renal Proximal Tubule Cells from Rat Models of ... Loss of NHERF-1 Expression Prevents Dopamine-Mediated Na-K-ATPase Regulation in Renal Proximal Tubule Cells from Rat Models of ... Animals; Blood Pressure; Cell Line; Disease Models, Animal; Dopamine; Gene Expression Regulation; Humans; Hypertension; Kidney ...
  http://hsrc.himmelfarb.gwu.edu/smhs_pharm_facpubs/187/
*  Plus it
Although the majority of tissues tested were negative, weak reactivity with cardiac muscle, proximal kidney tubules, and sweat ...
  http://cancerres.aacrjournals.org/content/50/19/6423
*  Endocrinology Flashcards by Alice Ridgeway | Brainscape
SGLT2: proximal tubule of kidney 98 What multifactorial interventions might be combined to most effectively treat diabetes? ... Arranged into tubular structures with a lumen: seminiferous tubules. Have basal compartment where spermatogonia divide and a ... Increases calcium reabsorption in kidney but inhibits reabsorption of phosphate Stimulates conversion of 25hydroxy vitamin D to ...
  https://www.brainscape.com/flashcards/endocrinology-4868863/packs/7201366
*  C Category Names List - Drug Information Portal - U.S. National Library of Medicine
Carbonic Anhydrase Inhibitors (12) • A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule ...
  https://druginfo.nlm.nih.gov/drugportal/drug/categories/c
*  The Proximal Nephron | SpringerLink
The proximal tubule of the mammalian kidney is the nephron site where the major portion, some two-thirds to... ... This chapter deals with an analysis of proximal tubular fluid and electrolyte transport. ... Proximal Tubule Basolateral Membrane Proximal Tubule Cell Proximal Convoluted Tubule Luminal Membrane These keywords were added ... The effect of d-glucose on the proximal electrical potential profile across the proximal tubule of newt kidney. Biochim. ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5404-8_14
*  Treatment of HK-2 with nLDL results in unbalance of the | Open-i
Kidney Tubules, Proximal/metabolism*. *Lipoproteins, LDL/metabolism*. *Oxidative Stress*. *Reactive Oxygen Species/metabolism* ... Native LDL-induced oxidative stress in human proximal tubular cells: multiple players involved. ... Native LDL-induced oxidative stress in human proximal tubular cells: multiple players involved. ... This study aimed to examine the effects of native non-oxidized LDL on cellular oxidative metabolism in cultured human proximal ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3822803_jcmm0015-0375-f1b&req=4
*  Immunoperoxidase labelling of Liu-FPN1 in rat kidney. ( | Open-i
Immunoperoxidase labelling of Liu-FPN1 in rat kidney. (A) Strong labelling is evident throughout the cortex and outer stripe of ... Ferroportin 1 is expressed basolaterally in rat kidney proximal tubule cells and iron excess increases its membrane trafficking ... Ferroportin 1 is expressed basolaterally in rat kidney proximal tubule cells and iron excess increases its membrane trafficking ... I) FPN1 and kidney electrogenic Na-bicarbonate cotransporter-1 (NBCe1-A) immunoreactivity in rat kidney cortex. Homogenate, ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3822789_jcmm0015-0209-f2a&req=4
*  Toxins | Free Full-Text | Deleterious Effects of Mycotoxin Combinations Involving Ochratoxin A | HTML
degenerations in kidney proximal tubules and proliferation in the interstitium (S). [104]. ... renal changes were seen in all parts of the kidney, but were most prominent in the mitochondria of proximal convoluted tubules ... More pronounced damage of proximal tubules in the kidney was observed in mice [99].PA inhibits carboxypeptidase-the enzyme ... Human proximal tubule cells. OTA (25 and 50 nm·L−1) + CIT (0.25 and 1 μmol·L−1)/24 h. No effect on caspase-3 activation. [82]. ...
  http://mdpi.com/2072-6651/5/11/1965/htm
*  Zebrafish Discovery May Shed Light on Human Kidney Function
... of how sodium ions pass through the gill of a zebrafish may be a clue to understanding a key function in the human kidney. The ... which requires the initial part of the kidney tubule (proximal tubule) to export ammonia/ammonium. Physiologically, it has been ... In humans, NHE3 is involved in the acid-waste control system in the kidney, but there hasn't been a good analysis of that ... Part of this acid-control process in the human kidney is "ammoniagenesis" ...
  http://www.newswise.com/articles/view/614045/?sc=rssn
*  EHHADH Gene - GeneCards | ECHP Protein | ECHP Antibody
Tissue specificity: Liver and kidney. Strongly expressed in the terminal segments of the proximal tubule. Lower amounts seen in ... Fanconi renotubular syndrome 3 (FRTS3) [MIM:615605]: A disease due to a generalized dysfunction of the proximal kidney tubule ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=EHHADH
*  Publications - Organovo
... tissue model of the human kidney proximal tubule. DOWNLOAD POSTERKidney, Presented at the American Society of Experimental ... Utilization of the ExVive Human Kidney Tissue Model of the Proximal Tubule to Assess Nephrotoxicity Across a Diverse Set of ... A 3D Bioprinted Model of the Renal Proximal Tubule for Evaluation of Drug-Induced Nephrotoxicity. DOWNLOAD POSTERKidney, ... 3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing. Shelby M. King, J.W. ...
  https://organovo.com/science-technology/publications/
*  KAKEN - Research Projects | Molecular and Cell Biological Analyzes of Structure and Function of Drug Transporters in the...
... and Cell Biological Analyzes of Structure and Function of Drug Transporters in the Intestine and Kidney Proximal Tubule. ... with the rat OAT-K1 cDNA demonstrated that OAT-K1 is localized at the basolateral membranes of renal proximal tubule and ... Publications] Y.Hashimoto: 'Functional evidence for an apical ANP receptor in LLC-PK1 kidney epithelial cells' Eur.J.Pharmacol. ... Publications] J. Nagai: 'Specificity of p-aminohippurate transport system in the OK kidney epithelial cell line' J. Pharmacol. ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-06454596/
*  Late Stage Functionalization of Drug-Like Molecules Session 2
The kidney MPS recapitulates the synthetic, metabolic and transport activities of kidney proximal tubule cells. This MPS is as ... 1. The kidney proximal tubule is the primary site of drug-induced nephrotoxicity. I will describe the development of a 3- ... dimensional flow-directed proximal tubule microphysiological system (MPS). ... kidney, and liver models for toxicology studies, blood-brain barrier models for drug transport studies, and vascularized tumor ...
  https://www.brighttalk.com/webcast/1238/143587