*  The Carb-Sane Asylum: Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of...
Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans. We previously ... Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans ... Human islets were obtained from the β-Cell Transplant Unit (Brussels, Belgium). Exposure to 0.125 mmol/l palmitate or oleate ... that in control islets, whereas the activity of PDH kinase (which inactivates PDH) was significantly increased in the same ...
  http://carbsanity.blogspot.com/2010/04/long-term-exposure-to-fatty-acids-and.html
*  Plus it
... islet cell-type segregation, architectural organization within islets of Langerhans, and state of differentiation, cell growth ... Cell contacts in human islets of Langerhans. J Clin Endocrinol Metab 1975;41:841-844pmid:1102552. ... Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation. J Cell Sci 1994; ... and hormone secretion (9-16). Hints that direct islet cell-to-islet cell interactions are required for proper insulin secretion ...
  http://diabetes.diabetesjournals.org/content/64/3/709
*  Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet | Diabetes
... the islet of Langerhans (1). Activation of muscarinic receptors leads to improved insulin secretion from pancreatic islets (2-7 ... Pancreatic Islets. We obtained human pancreatic islets from deceased donors from the Human Islet Cell Processing Facility at ... Unique arrangement of alpha- and beta-cells in human islets of Langerhans. Diabetes 2010;59:1202-1210pmid:20185817. ... Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function. Diabetes 2009;58 ...
  http://diabetes.diabetesjournals.org/content/63/8/2714?rss=1
*  Administration of a murine interleukin-1 cytokine trap counteracts the recurrence of disease following syngeneic islet...
Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which T-cells and macrophages invade the islets of Langerhans and ... Also, it was sufficient to block the action of IL-1β to prevent islet cell death induced by a combination of IL-1β, tumor ... In study III, a murine IL-1 trap was found to prolong islet graft survival in the recurrence of disease (ROD) model, a T1DM ... Here we found that an IL-1 trap could prevent the suppressive effects by IL-1β on rat pancreatic islet function. ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:170931
*  TGF-βi Promotes Islet β-Cell Function and Regeneration | The Journal of Immunology
Integrin signaling via RGD peptides and anti-beta1 antibodies confers resistance to apoptosis in islets of Langerhans. Diabetes ... D, Tg islets secrete human TGF-βi into culture supernatants. One hundred islets from line 30310 Tg mice and 300 islets from ... Islets with 70% loss of their capsule were considered as having lost their integrity. The percentage of islets (∼100 islets/ ... The islet integrity index was calculated as follows: integrity index = 100% × (number of total islets − number of islets with ...
  http://www.jimmunol.org/content/186/10/5833.long
*  Prolactin treatment improves engraftment and function of transplanted pancreatic islets
Angiogenesis, Islet graft, Islet of Langerhans, Prolactin, Thrombospondin-1 National Category Medical and Health Sciences ... 1. Role of Islet Endothelial Cells in β-cell Function and Growth. Open this publication in new window or tab ,,Role of Islet ... The pancreatic islets are collections of endocrine cells, dispersed throughout the pancreas. In adult islets, endocrine cells ... Moreover, prolactin pretreatment in vitro of islets used for transplantation improved recovery from diabetes in a minimal islet ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:207345
*  British Library EThOS: Transplantation of organ cultured foetal islets of Langerhans in mice
Foetal islets are functionally immature but retain their capacity for proliferation if harvested and cultured in an appropriate ... studies using NOD recipient mice as a model for IDDM showed that recurrent autoimmune disease was seen in foetal islet ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696209
*  Dendritic Cells and Macrophages Are the First and Major Producers of TNF-α in Pancreatic Islets in the Nonobese Diabetic Mouse ...
To confirm that DC/Mφ infiltration in the islets of Langerhans is a feature specific for diabetes development, we stained ... Although these results suggest that initial DC/Mφ infiltration into the islets of Langerhans can occur independently of T cells ... Levels of mononuclear cell infiltration in islets of Langerhans were determined in NOD mice at various ages. Cryosections (8 μm ... Kinetics of mononuclear cell infiltration and TNF-α expression in the islets of Langerhans in the NOD mouse. Pancreatic ...
  http://www.jimmunol.org/content/160/7/3585.long
*  British Library EThOS: Expression and roles of the lipid-responsive receptors GPR119 and GPR120 in pancreatic islets
The various endocrine cell types present in mammalian Islets of Langerhans express a range of lipid-responsive G-proteln ... the studies demonstrate that GPR119 and GPR120 may play roles in the control of islet hormone secretion but they do not appear ... These are each reported to be expressed In islet beta-cells and GPR 119 has been Implicated In the augmentation of glucose- ... Expression and roles of the lipid-responsive receptors GPR119 and GPR120 in pancreatic islets ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.566051
*  Islet cells financial definition of islet cells
What is islet cells? Meaning of islet cells as a finance term. What does islet cells mean in finance? ... Definition of islet cells in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... Related to islet cells: islets of Langerhans cell. an independent team of operatives who work together in a CELLULAR ... Islet cells financial definition of islet cells https://financial-dictionary.thefreedictionary.com/islet+cells ...
  https://financial-dictionary.thefreedictionary.com/islet+cells
*  Islets of Langerhans | SpringerLink
It is a major reference book, the first of its kind, for islet researchers, and ... and recent advances made in essentially all areas of islet research. ... islets of model animals, immunology, proteomics, regenerative medicine, clinical advances, and islet transplantation. ... Regulation of Pancreatic Islet Formation Manuel Carrasco, Anabel Rojas, Irene Delgado, Nadia Cobo Vuilleumier, Juan R. Tejedo, ...
  https://link.springer.com/referencework/10.1007/978-94-007-6686-0
*  Islets of Langerhans definition | Drugs.com
Definition of islets of Langerhans. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and ... islets of Langerhans. Pronunciation: lahng'er-hahnz. Definition: cellular masses consisting of several to several hundred cells ...
  https://www.drugs.com/dict/islets-of-langerhans.html
*  Islets of Langerhans - Biology-Online Dictionary
The name came from the German anatomist, Paul Langerhans, who first described them in 1869. The islets of Langerhans make up ... The other cells that make up the islets of Langerhans include delta cells (producing somatostatin), gamma cells (producing ... The cells in the pancreas that carry out endocrine functions are the islets of Langerhans. ... In humans, the two major cells of the islets are the alpha cells and the beta cells. The alpha cells produce glucagon whereas ...
  https://www.biology-online.org/dictionary/Pancreatic_islets
*  Gene Combination Transfer to Block Autoimmune Damage in Transplanted Islets of Langerhans
... Suzanne Bertera,1 Angela M. ... Islet transplantation therapy would be applicable to a wider range of diabetic patients if donor islet acceptance and ... To this aim, gene transfer to isolated donor islets ex vivo is one method that has shown promise. This study examines the ... were transferred to isolated NOD donor islets ex vivo then transplanted to NODscid recipients and evaluated in vivo after ...
  https://www.hindawi.com/journals/jdr/2004/951809/abs/
*  Angiogenesis and Hemodynamics of Microvasculature of Transplanted Islets of Langerhans | Diabetes
Transplantation of isolated islets of Langerhans is frequently followed by early loss of islet function. Because whether this ... Angiogenesis and Hemodynamics of Microvasculature of Transplanted Islets of Langerhans. Michael D Menger, Sabine Jaeger, Paul ... Angiogenesis and Hemodynamics of Microvasculature of Transplanted Islets of Langerhans. Michael D Menger, Sabine Jaeger, Paul ... Angiogenesis and Hemodynamics of Microvasculature of Transplanted Islets of Langerhans Message Subject (Your Name) has ...
  http://diabetes.diabetesjournals.org/content/38/Supplement_1/199
*  Islets of Langerhans | definition of islets of Langerhans by Medical dictionary
What is islets of Langerhans? Meaning of islets of Langerhans medical term. What does islets of Langerhans mean? ... Looking for online definition of islets of Langerhans in the Medical Dictionary? islets of Langerhans explanation free. ... Synonym(s): islet tissue, Langerhans islands, pancreatic islands, pancreatic islets. islets of Langerhans. (ī′lĭts; läng′ər- ... Langerhans islands - Synonym(s): islets of Langerhans. islets of Langerhans. pancreatic secretory cells; alpha cells release ...
  http://medical-dictionary.thefreedictionary.com/islets+of+Langerhans
*  ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS | JCB
ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS. S. L. Howell, D. A. Young, P. E. Lacy ... A partially purified secretory granule fraction, isolated from rat islets of Langerhans by differential centrifugation, was ... no specific insulin-degrading activity could be detected in subcellular fractions of the islets. These findings indicate that ...
  http://jcb.rupress.org/content/41/1/167
*  Intracellular Ca2+ mobilization in isolated rat islets of Langerhans | Biochemical Society Transactions
Intracellular Ca2+ mobilization in isolated rat islets of Langerhans. NOEL G. MORGAN, ROGER D. HURST, GWYNETH M. RUMFORD, ... Intracellular Ca2+ mobilization in isolated rat islets of Langerhans. NOEL G. MORGAN, ROGER D. HURST, GWYNETH M. RUMFORD, ... Intracellular Ca2+ mobilization in isolated rat islets of Langerhans Message Subject (Your Name) has forwarded a page to you ...
  http://www.biochemsoctrans.org/content/15/5/939
*  EFFECT OF DEHYDROASCORBIC ACID ON THE ISLETS OF LANGERHANS OF THE RAT PANCREAS | JCB
EFFECT OF DEHYDROASCORBIC ACID ON THE ISLETS OF LANGERHANS OF THE RAT PANCREAS. Dino Merlini, Felice Caramia ... EFFECT OF DEHYDROASCORBIC ACID ON THE ISLETS OF LANGERHANS OF THE RAT PANCREAS ... Rat pancreatic islets have been studied following successive daily administration of dehydroascrobic acid (DHA) and during the ...
  http://jcb.rupress.org/content/26/1/245
*  Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic...
24 ng/islet in high fat-fed animals vs. 150 ± 43 ng/islets in regular diet-fed animals, n = 6, NS; GK rats: 127 ± 33 ng/islet ... 65 ± 11 μU/islet; n = 6, P , 0.05; succinic acid monomethyl ester: 17 ± 5 vs. 52 ± 12 μU/islet, n = 6, P , 0.05) (Fig. 2B). ... 1,676 ± 124 μU/islet, n = 6, NS) or Wistar rats (1,884 ± 238 vs. 1,831 ± 158 μU/islet, n = 6, NS). Insulin mRNA levels were ... 1,831 ± 158 μU/islet, n = 6, NS). Insulin content was not significantly modified by the high-fat diet in islets from GK rats ( ...
  http://diabetes.diabetesjournals.org/content/51/3/662
*  "Elucidating the Function of Transplanted Islets of Langerhans" by Andrew R. Pepper
This approach of ascertaining islet transplant function prior to engraftment incorporated the influence of islet morphology to ... In all cases this OCR/II index proved to have a significantly greater predictive capacity of the ability of a given islet ... The initial aim of this graduate work was to study existing pre-transplant assays of islet function and to critically examine ... In the near future it is hoped that the knowledge gained from this work will be employed in clinical islet transplantation. ...
  https://ir.lib.uwo.ca/etd/652/
*  Peter Kiss Gallery Islets of Langerhans - Peter Kiss Gallery
Materials: Acrylic on wood, silver leaf, on panel. Dimensions: 36" X 36" X 5" Price: $2400. Galleries: 2.5 Dimensional Paintings ...
  http://peterkiss.com/artwork/untitled-silver-leaf/
*  Music on Earthrid - Earthrid
Adrift off the Islets of Langerhans. Majestic mood music from Yorkshire's master of ambience.. Released 13th September 2010. ...
  http://earthrid.com/releases/