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*  Toxic leukoencephalopathy - Wikipedia
The dose-response relationship for these substances remains unclear. Various chemotherapy drugs have shown increased risk of ... Leukoencephalopathy may result from the inhalation, intravenous injection, or ingestion of substance abuse drugs. However, such ... The prevalence of this disease is infrequent and often goes unreported, especially in cases resulting from drug abuse. Magnetic ... Toxic leukoencephalopathy may also result from carbon monoxide poisoning, ingestion of methanol, ingestion of ethylene, toluene ...
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*  Guideline for opioid therapy and chronic noncancer pain | CMAJ
... "no evidence was found for a dose-response relationship between opioid dose and the outcomes of addiction and diversion. The ... from oral to nasal or intravenous injection). They do not reduce the most common mode of misuse (oral ingestion), but are less ... The terms "urine drug screening" and "urine drug testing" are often used interchangeably and do not represent an inconsistency ... "a clear dose-response relationship was demonstrated for the outcomes of fatal and non-fatal overdose (pp 62, 65). ...
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*  Chapter 5
A dose-response relationship means there is a correlation between a response and the quantity of drug administered; such a ... In intravenous injection, the drug is delivered directly into the bloodstream, so high concentrations of a drug can be ... oral ingestion, injection, inhalation, and topical application. In oral ingestion, drug chemicals must withstand the digestive ... Because each drug can produce many effects, many dose-effect relationships can be studied for a given drug. Researchers measure ...
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*  Industrial hemp is not marijuana
... the doseresponse profile resembles that of an intravenous injection, with its characteristically fast peak of plasma drug ... This dose response was particularly clear between the 1.32% and the 2.54% cigarettes.'. Similar relationships between THC ... High THC concentrations in Cannabis smoke allow drug ingestion within a short period of time resulting in high maximum plasma ... The effects of orally administered delta-9-tetrahydrocannabinol in man on mood and performance measures: a dose-response study. ...
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*  US6326364B1 - Use of 5-aminosalicylates as antimicrobial agents - Google Patents
Mulder, et al; Drug Therapy: Dose-Response Relationship of Oral Mesalazine in Inflammatory Bowel Disease; Mediators Inflamm; ... 8. The method of claim 7, wherein said systemic delivery route is by ingestion, injection, intravenous drip, or implant. ... 78(6):1413-25 [1994]; C. J. Mulder et al., Drug therapy. dose-response relationship of oral mesalazine in inflammatory bowel ... The method of claim 21, wherein said systemic delivery route is by ingestion, injection, intravenous drip, or implant. ...
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*  687. Modified celluloses (WHO Food Additives Series 26)
... did not show a consistent dose-response relationship. After 6 months, decreased body weight was noted at the high dose level, ... In dogs, single intravenous injections of 40 ml of 0.7 to 2.8% solutions of methyl cellulose in saline resulted, within 24 ... Submitted to WHO by the U.S. Food and Drug Administration. FOOD & DRUG RESEARCH LABORATORIES Inc. (1975). Teratologic ... ANDERSON, D.M.W. (1986). Some dietary effects of the ingestion of sodium carboxymethylcellulose by man and rodents. Unpublished ...
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*  Nutrients | Free Full-Text | A Balanced Risk-Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids...
There is no epidemiological evidence, however, for human risks of regular low dose PA exposure. Recommended regulatory PA- ... studies on the association between tea drinking and a risk reduction for depression produced a dose response relationship: A ... Intravenous injection of thorium dioxide induced hepatocellular carcinomas in hamsters and liver carcinomas, intrahepatic bile- ... Food and Drug Administration. Guidance for Industry: Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for ...
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*  Citations Appearing in 2003 | BMSR Biomedical Simulations Resource | USC
Luteal phase dose-response relationships of the antiprogestin CDB-2914 in normally cycling women. Human Reproduction 18(9):1820 ... Oral/intravenous maintenance dosing of valproate following intravenous loading: a simulation. Epilepsy Research 53(1-2):29-38, ... Drug Metabolism and Disposition 31(4):462-468, 2003.. *Klausner, E.A., E. Lavy, D. Stepensky, E. Cserepes, M. Barta, M. ... Gender difference in the pharmacokinetics of ethanol in saliva and blood after oral ingestion. Polish Journal of Pharmacology ...
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*  Cimetidine Injection - FDA prescribing information, side effects and uses
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*  Compounds, Formulations, and Methods of Protein Kinase C Inhibition - Patent application
... dose-response assays to determine their potencies. Further structure-activity relationships (SAR) were performed using Kinase- ... Animals received an intra-vitreal injection of either vehicle (PBS), VEGF (50 ng), PKC-zeta inhibitor pro-drug (PKCζl-PD) at ... The amount of coating material applied to a solid dosage generally dictates the time interval between ingestion and drug ... Sterile solutions or dispersions are suitable for injection (e.g., subcutaneous, intramuscular, intravenous, intracerebral, or ...
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*  Aripiprazole Tablets (Aripiprazole Tablets): Side Effects, Interactions, Warning, Dosage & Uses
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*  Andrei Iagaru | Stanford Medicine Profiles
Dose-response relationships were determined for efficacy and toxicity.Patients were treated with a median of 1.73 GBq activity ... The investigational drug will be given as a single administration in a dose of ,/= 0.1 mg BAY94-9392 (300 MBq, +/- 10%). The ... Blood samples were obtained before the injection of (18)F-FPPRGD2 and at 24 hours and 1 week after injection to evaluate for ... A 56-year-old woman with prior esophageal resection and reconstruction after accidental lye ingestion presented for management ...
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*  Endocannabinoids Acting at Cannabinoid-1 Receptors Regulate Cardiovascular Function in Hypertension | Circulation
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*  Drug Use in America - Defining the Issues
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*  Indian Patents. 256041:GLP-1 PEGYLATED COMPOUNDS
Xaa33 is Ile; and Xaa46 is Cys-NH2 is administered by intravenous (IV) or subcutaneous. (SC) routes at a dose of 0.1 mg/kg to ... cells of the intestine in response to food ingestion. Numerous GLP-1 analogs and. derivatives have been described in the art. ... the injection of a dosage form into the body by a sterile syringe or some other mechanical. device such as an infusion pump. ... However, this reciprocal relationship is exact only when there is no change in. the volume of distribution. A useful ...
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*  Flame retardants (EHC 209, 1998)
It was impossible, therefore, to determine the dose-response relationship for these effects. 7.8 Other studies 7.8.1 ... Groups of 2-8 male Sprague-Dawley rats received an unstated amount of 14C-TDCPP by intravenous injection (Lynn et al., 1981). ... La toxicit aig e du TCPP se r v le faible mod r e apr s ingestion (DL50 pour le rat= 1017 4200 mg/kg de poids corporel), ... Drug Metab Dispos, 9(5): 434-441. Matthews HB, Dixon D, Herr DW, & Tilson H (1990) Subchronic toxicity studies indicate that ...
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*  OXYNTOMODULIN PEPTIDE ANALOGUE - Patent application
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*  ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt #3: Adjunctive Therapies, Part 2 of 3
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*  Patent US20020031508 - Methods for diagnosing and treating hemostatic disorders by modulating P ... - Google Patents
... expected drug effects or show exaggerated drug response and serious toxicity after taking the standard and safe dose of a drug ... intravenous injection, local administration (see U.S. Pat. No. 5,328,470) or by stereotactic injection (see e.g., Chen et al. ( ... the study of the relationship between an individual's genotype and that individual's response to a foreign compound or drug) ... is a common inherited enzymopathy in which the main clinical complication is haemolysis after ingestion of oxidant drugs (anti- ...
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