*  140914: Interleukin-4, Serum | LabCorp
Interleukin-4. In: Thomson AW, Lotze MT, eds. Cytokine Handbook. Vol 1, 4th ed. San Diego, Calif: Academic Press; 2003: 227-262 ... Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T lymphocytes, CD3+ cells, NK-T cells, mast cells, ... In addition, IL-4 has also been shown to have antitumor activity both in vivo and in vitro.1 ... eosinophils, and basophils.1 IL-4 has multiple immune response modulation functions on a variety of cell types. It is an ...
  https://www.labcorp.com/test-menu/29776/interleukin-4-serum
*  Interleukin 4 - Wikipedia
It is closely related and has functions similar to Interleukin 13. Interleukin 4 has many biological roles, including the ... The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon ... The receptor for Interleukin-4 is known as the IL-4Rα. This receptor exists in 3 different complexes throughout the body. Type ... Interleukin-4 at the US National Library of Medicine Medical Subject Headings (MeSH) Interleukin-4 from Gentaur at Gentaur ...
  https://en.wikipedia.org/wiki/Interleukin_4
*  Interleukin-4 receptor - Wikipedia
The interleukin 4 receptor is a type I cytokine receptor. IL4R is its human gene. This gene encodes the alpha chain of the ... Interleukin-4 receptor has been shown to interact with SHC1. The N-terminal (extracellular) portion of interleukin-4 receptor ... They are required for binding of interleukin-4 to the receptor alpha chain, which is a crucial event for the generation of a ... Among T cells, the encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the ...
  https://en.wikipedia.org/wiki/Interleukin-4_receptor
*  Il4 - Interleukin-4 precursor - Rattus norvegicus (Rat) - Il4 gene & protein
positive regulation of interleukin-10 production Source: RGD ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct ... positive regulation of interleukin-13 production Source: Ensembl. *positive regulation of isotype switching to IgE isotypes ... sp,P20096,IL4_RAT Interleukin-4 OS=Rattus norvegicus GN=Il4 PE=2 SV=2 ... IPR009079. 4_helix_cytokine-like_core. IPR002354. IL-4. IPR001325. IL-4/IL-13. IPR018096. IL-4/IL-13_CS. ...
  http://www.uniprot.org/uniprot/P20096
*  Interleukin-4 in the treatment of AIDS-related Kaposi's sarcoma.
IL-4) when administered subcutaneously in patients with AIDS-related Kaposi's sarcoma (AIDS-KS); to evaluate the effect of IL-4 ... To define the safety and toxicity of interleukin-4 ( ... Interleukin-4 in the treatment of AIDS-related Kaposi's sarcoma ... Interleukin-4 / administration & dosage, adverse effects, therapeutic use*. Lymphocyte Count / drug effects. Male. Middle Aged ... PURPOSE: To define the safety and toxicity of interleukin-4 (IL-4) when administered subcutaneously in patients with AIDS- ...
  http://www.biomedsearch.com/nih/Interleukin-4-in-treatment-AIDS/9093711.html
*  Interleukin-4 or IL4 Antibody
IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T ... Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially ... IL-4 staining of frozen tissue sections of human lymph node. Sections were stained using anti-mouse ABC-HRP, NovaRed (red) ... IL-4 staining of frozen tissue sections of human lymph node. Sections were stained using anti-mouse ABC-HRP, NovaRed (red) ...
  https://www.neuromics.com/MO15071
*  Receptors, Interleukin-4, Type I - RightDiagnosis.com
Interleukin-4, Type I information including symptoms, causes, diseases, symptoms, treatments, and other medical and health ... Receptors, Interleukin *Interleukin-4 *Type Interesting Medical Articles:. *Symptoms of the Silent Killer Diseases *Online ... Description of Receptors, Interleukin-4, Type I. Receptors, Interleukin-4, Type I: An interleukin-4 receptor subtype that is ... Receptors, Interleukin-4, Type I: Related Topics. These medical condition or symptom topics may be relevant to medical ...
  http://www.rightdiagnosis.com/medical/receptors_interleukin_4_type_i.htm
*  Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation | JEM
Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation. Jinfang Zhu, Hua Huang, Liying Guo, Timothy ... 1995) Interleukin 4 signals through two related pathways. Proc. Natl. Acad. Sci. USA. 92:7971-7975, pmid:7544011.. ... 1997) Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cellsstat6 is probably not required for the effect of IL-4. ... Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation. Jinfang Zhu, Hua Huang, Liying Guo, Timothy ...
  http://jem.rupress.org/content/192/8/1125
*  Macrophage activation by lipopolysaccharide, interferon-γ and interleukin-4: effect of fatty acid metabolism
... H. Darmani,1 J. L ... interferon-γ and interleukin-4: effect of fatty acid metabolism," Mediators of Inflammation, vol. 4, no. 1, pp. 25-30, 1995. ... Volume 4, Issue 1, Pages 25-30. http://dx.doi.org/10.1155/S0962935195000056. ...
  https://www.hindawi.com/journals/mi/1995/970754/cta/
*  Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. - PubMed - NCBI
Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which ... Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.. LaPorte SL1, Juo ZS, ... Molecular and structural basis of cytokine receptor pleiotropy in the Interleukin-4/13 system ... Molecular and structural basis of cytokine receptor pleiotropy in the Interleukin-4/13 system ...
  https://www.ncbi.nlm.nih.gov/pubmed/18243101
*  RCSB PDB - 1HIJ: INTERLEUKIN-4 MUTANT WITH ARG 88 REPLACED WITH GLN (R88Q) Macromolecule Annotations Page
Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic ... 4-helical cytokines 4-helical cytokines Short-chain cytokines Interleukin-4 (IL-4) Human (Homo sapiens) [TaxId: 9606] ...
  http://www.rcsb.org/pdb/explore/derivedData.do?structureId=1HIJ
*  Serum Interleukin-4 and Total Immunoglobulin E in Nonatopic Alopecia Areata Patients and HLA-DRB1 Typing
... Enas A. S. Attia,1 ... K. Katagiri, S. Arakawa, and Y. Hatano, "In vivo levels of IL-4, IL-10, TGF-β1 and IFN-γ mRNA of the peripheral blood ... 4, no. 3, pp. 216-219, 1999. View at Google Scholar · View at Scopus ... 4, pp. 549-570, 2000. View at Google Scholar · View at Scopus ... 4, pp. 530-533, 1994. View at Google Scholar · View at Scopus ...
  https://www.hindawi.com/journals/drp/2010/503587/ref/
*  Decreased Interleukin-4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress
3.2.1. Interleukin-4 (IL-4). Concentration of IL-4 protein was assessed in the 100 μg aliquot of the LC in the IMO-subjected ... Interleukin-4 (IL-4) is an anti-inflammatory cytokine and has an ability to inhibit synthesis of IL-1β, a proinflammatory ... Decreased Interleukin-4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress. Hyun-ju Lee,1 ... 2.4.1. Interleukin-4 (IL-4). After all stress procedures were done, the animals were deeply anesthetized with sodium ...
  https://www.hindawi.com/journals/mi/2016/3501905/
*  Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells | Cancer Research
Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells. Maria Giovanna Francipane, Mileidys Perez Alea, ... Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells ... Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells ... Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells ...
  http://cancerres.aacrjournals.org/content/68/11/4022.figures-only
*  Recombinant Human Interleukin 4 Receptor IL4R-1645H - Creative BioMart
IL4R(Human)(IL4R, interleukin 4 receptor) can be used for N/A. ... interleukin-4 receptor alpha chain; CD_antigen; IL-4R-alpha; ... Purified Recombinant Human Interleukin 4 Receptor from Creative Biomart. ... Recombinant Human Interleukin 4 Receptor. Download Datasheet See All IL4R Products. Bring this labeled protein directly to your ... IL4R interleukin 4 receptor [ Homo sapiens ]. Synonyms:. IL4R; interleukin 4 receptor; CD124; IL4RA; interleukin 4 receptor ...
  https://www.creativebiomart.net/description_6420_14.htm
*  interleukin-4 - oi
Increased Serum Interleukin-10 but not Interleukin-4 Level in Children with Mycoplasma pneumoniae Pneumonia ... Modulation of CD4+ and CD8+ T-Cell Function by Interleukin 19 and Interleukin 24 During Filarial Infections ... Interleukin-4 in the treatment of AIDS-related Kaposi's sarcoma Epithelial interleukin-4 receptor expression promotes colon ... Interleukin4 inhibits interleukin‐11 production by rheumatoid synovial cells Association of Severe Respiratory Syncytial Virus ...
  http://oxfordindex.oup.com/view/10.1093/oi/authority.20110803100006930
*  Association between Polymorphisms in Interleukins 4 and 13 Genes and Chronic Periodontitis in a Han Chinese Population
C. G. McFarlane and M. C. Meikle, "Interleukin-2, interleukin-2 receptor and interleukin-4 levels are elevated in the sera of ... R. W. B. Bottema, I. M. Nolte, T. D. Howard et al., "Interleukin 13 and interleukin 4 receptor-α polymorphisms in rhinitis and ... H. Kabashima, K. Nagata, I. Hashiguchi et al., "Interleukin-1 receptor antagonist and interleukin-4 in gingival crevicular ... A. A. Te Velde, R. J. F. Huijbens, K. Heije, J. E. De Vries, and C. G. Figdor, "Interleukin-4 (IL-4) inhibits secretion of IL-1 ...
  https://www.hindawi.com/journals/bmri/2016/8389020/ref/
*  Interleukin-4 in the Generation of the AERD Phenotype: Implications for Molecular Mechanisms Driving Therapeutic Benefit of...
Interleukin-4 in the Generation of the AERD Phenotype: Implications for Molecular Mechanisms Driving Therapeutic Benefit of ... John W. Steinke, Spencer C. Payne, and Larry Borish, "Interleukin-4 in the Generation of the AERD Phenotype: Implications for ...
  https://www.hindawi.com/journals/ja/2012/182090/cta/
*  Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells
CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J Exp Med. 1994 Apr 1; ... Kühn R, Rajewsky K, Müller W. Generation and analysis of interleukin-4 deficient mice. Science. 1991 Nov 1;254(5032):707-710. [ ... Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4. Proc ... Interleukin-4-producing CD4+ NK1.1+ TCR alpha/beta intermediate liver lymphocytes are down-regulated by Listeria monocytogenes ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2192838/?lang=en-ca
*  Integrin-regulated Secretion of Interleukin 4: A Novel Pathway of Mechanotransduction in Human Articular Chondrocytes | JCB
Antibodies to interleukin 1β (IL-1β) and cytokine receptors, interleukin 1 receptor type I and the common γ chain/CD132 (γ) ... interleukin. IP3. inositol triphosphate. MMP. matrix metalloproteinase. OA. osteoarthritis. PIS. pressure-induced strain. PLC. ... 1996) Interleukin-4 expression in normal and osteoarthritic human articular cartilage. J Rheumatol 23:1314-1315, pmid:8823723. ... 1996) cDNA cloning and characterization of the human interleukin-13 receptor alpha chain. J Biol Chem 271:29265-29270, pmid: ...
  http://jcb.rupress.org/content/145/1/183
*  A Phase I/II Study of Recombinant Interleukin-4 in AIDS and Kaposi's Sarcoma - Full Text View - ClinicalTrials.gov
A Phase I/II Study of Recombinant Interleukin-4 in AIDS and Kaposi's Sarcoma. The safety and scientific validity of this study ... Miles SA, Mitsuyasu R, LaFleur F, Ryback M, Kasden P, Suckow C, Groopman J, Scadden D. Phase I/II trial of interleukin-4 in KS ... To determine the safety and tolerance of interleukin-4 (IL-4) in patients with AIDS-related Kaposi's sarcoma. To determine the ... Interleukin-4. Adjuvants, Immunologic. Immunologic Factors. Physiological Effects of Drugs. Antineoplastic Agents. ...
  https://clinicaltrials.gov/show/NCT00000769?order=25
*  The Effects of Gene Polymorphisms in Interleukin-4 and Interleukin-6 on the Susceptibility of Rheumatoid Arthritis in a Chinese...
A. Cantagrel and F. Navaux, "Interleukin-1β, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene ... G. H. Zheng, H. Y. Chen, and S. Q. Xiong, "Polymorphisms of -174G,C and -572G,C in the interleukin 6 (IL-6) gene and coronary ... Y. H. Lee, S. C. Bae, S. J. Choi, J. D. Ji, and G. G. Song, "The association between interleukin-6 polymorphisms and rheumatoid ... Y. M. Hussein, A. S. El-Shal, N. A. Rezk, S. M. Abdel Galil, and S. S. Alzahrani, "Influence of interleukin-4 gene ...
  https://www.hindawi.com/journals/bmri/2014/265435/ref/
*  Correlation of serum tumor necrosis factor-α, interleukin-4 and soluble interleukin-2 receptor levels with radiologic and...
Correlation of serum tumor necrosis factor-α, interleukin-4 and soluble interleukin-2 receptor levels with radiologic and ... and soluble interleukin-2 receptor (sIL-2R) response. We further evaluated whether the levels of TNF-α, IL-4 and soluble IL-2R ... but there was no correlation between IL-4 and TNF-α, and between IL-4 and sIL-2R (. r. =. −. 0.23. and r. =. −. 0.22. ). . The ... Results of this study provided some evidence confirming the previously reported role of TNF-α, IL-4 and sIL 2R in the control ...
  https://www.hindawi.com/journals/mi/2003/470134/abs/
*  Intracellular signaling networks in the immune response: Interleukin-4 introduces competition and cooperation to interleukin-2...
The cytokines interleukin-2 (IL-2) and interleukin-4 (IL-4) are key regulators of the immune system, influencing the expansion ... Intracellular signaling networks in the immune response: Interleukin-4 introduces competition and cooperation to interleukin-2- ... Intracellular signaling networks in the immune response: Interleukin-4 introduces competition and cooperation to interleukin-2- ... Intracellular signaling networks in the immune response: Interleukin-4 introduces competition and cooperation to interleukin-2- ...
  http://www.jimmunol.org/content/178/1_Supplement/LB12.2
*  Interleukin 4 increases human synovial cell expression of VCAM-1 and T cell binding. | Annals of the Rheumatic Diseases
OBJECTIVE--The effects were studied of interleukin 4 (IL-4) on T cell-synovial cell adhesion and on the expression of adhesion ... Interleukin 4 increases human synovial cell expression of VCAM-1 and T cell binding. ... Interleukin 4 increases human synovial cell expression of VCAM-1 and T cell binding. ... IL-4 considerably enhanced the expression of VCAM-1 on the surface of synovial cells, but not the expression of ICAM-1 and ELAM ...
  http://ard.bmj.com/content/53/9/601