*  Dose-effect Relationship of Low-dose IL-2 in Type 1 Diabetes - Full Text View - ClinicalTrials.gov
This is in part due to a deficit in production of, or response to, interleukin 2 (IL-2). This cytokine is essential to Treg ... Interleukin-2. Antineoplastic Agents. Analgesics, Non-Narcotic. Analgesics. Sensory System Agents. Peripheral Nervous System ... Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial. Lancet ... Experimental: IL2-2 1 millions IU of IL-2 per day. Drug: Aldesleukin 0.33 ; 1 ; 3 ; 0 millions IU of IL-2 per day for arm 1 to ...
  https://clinicaltrials.gov/ct2/show/study/NCT01353833?view=results
*  Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma - Full Text View - ClinicalTrials.gov
Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma. The safety and scientific validity of this study is the ... Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Melanoma vaccine plus interleukin-2 may kill ... Interleukin-2. Immunologic Factors. Physiological Effects of Drugs. Antineoplastic Agents. Analgesics, Non-Narcotic. Analgesics ... Patients receive gp100:209-217(210M) emulsified in Montanide ISA-51 SC on day 1 and interleukin-2 SC on days 1-5 and 8-13. ...
  https://clinicaltrials.gov/ct2/show/NCT00005949
*  The IL-15 receptor α chain cytoplasmic domain is critical for normal IL-15Rα function but is not required for trans...
Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 2002;195:1541-1548. ... The roles of interleukin-15 receptor alpha: trans-presentation, receptor component, or both? Int J Biochem Cell Biol 2005;37: ... Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp ... Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 1993;73:147- ...
  http://www.bloodjournal.org/content/112/12/4411?sso-checked=true
*  Phase I/II Study Evaluating the Infusion of Tumor-Infiltrating Lymphocytes (TILs) and Low-Dose Interleukin-2 (IL-2) Therapy...
This study will see how safe and useful infusion of tumor infiltrating lymphocytes and interleukin-2 therapy following a ... Phase I/II Study Evaluating the Infusion of Tumor-Infiltrating Lymphocytes (TILs) and Low-Dose Interleukin-2 (IL-2) Therapy ... Phase I/II Study Evaluating the Infusion of Tumor-Infiltrating Lymphocytes (TILs) and Low-Dose Interleukin-2 (IL-2) Therapy ...
  http://adisinsight.springer.com/trials/700255825?error=cookies_not_supported&code=6d109e67-4ccd-4f78-8432-911af08bc6bb
*  interleukin-2 - Everything2.com
Interleukin-2 (IL-2) is a small quaternary structure,monomeric protein 133 amino acid,amino acids in length. It is a very ... Interleukin-2 (IL-2) is a small monomeric protein 133 amino acids in length. It is a very important cytokine in the immune ... It interacts with the IL-2 receptor, which sits on the cell surface of T-cells and transmits a signal into the cells which then ...
  https://everything2.com/title/interleukin-2
*  140812: Interleukin-2, Plasma | LabCorp
Interleukin-2. In: Thomson AW, Lotze MT, eds. Cytokine Handbook. 4th ed, vol 1. London, UK and San Diego, Calif: Academic Press ... Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen-activated T lymphocytes.1 IL-2 plays a ... In vitro studies suggest that IL-2 may also be produced by dendritic cells and certain lymphoma cell lines.1 In addition, IL-2 ... IL-2 stimulates the proliferation of thymocytes; stimulates the proliferation and differentiation of activated B cells; ...
  https://www.labcorp.com/test-menu/29756/interleukin-2-plasma
*  WikiGenes - IL2 - interleukin 2
Induction of lymphokine-activated killer activity by interleukin 4 in human lymphocytes preactivated by interleukin 2 in vivo ... Costimulation of cutaneous T-cell lymphoma cells by interleukin-7 and interleukin-2: potential autocrine or paracrine effectors ... Interleukin 15 (IL-15) is a novel cytokine with interleukin-2-like activity [46]. ... interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: association with psychopathology. Zhang, X.Y., ...
  https://www.wikigenes.org/e/gene/e/3558.html
*  Interleukin 2 Porcine | ProSpec
Interleukin2 Porcine Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 134 amino acids ... Interleukin2 Porcine Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 134 amino acids ... The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and ... interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory ...
  https://www.prospecbio.com/IL-2_Porcine
*  Interleukin 2 - Wikipedia
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a protein that ... Interleukin-2 (Aldesleukin). Date accessed: 07 Nov 10. Shi VY, Tran K, Patel F, Leventhal J, Konia T, Fung MA, Wilken R, Garcia ... Aldesleukin is a form of recombinant interleukin-2. It is manufactured using recombinant DNA technology and is marketed as a ... Welte K, Wang CY, Mertelsmann R, Venuta S, Feldman SP, Moore MA (August 1982). "Purification of human interleukin 2 to apparent ...
  https://en.wikipedia.org/wiki/Interleukin_2
*  Interleukin-2 in Metastatic Melanoma - Full Text View - ClinicalTrials.gov
Interleukin-2 in Metastatic Melanoma. The safety and scientific validity of this study is the responsibility of the study ... Interleukin-2. Antineoplastic Agents. Analgesics, Non-Narcotic. Analgesics. Sensory System Agents. Peripheral Nervous System ... To determine whether Interleukin-2 at the dose and schedule will help to increase tumor shrinkage ... Phase II Trial of Moderate Dose Bolus Interleukin-2 in Metastatic Melanoma. ...
  https://clinicaltrials.gov/ct2/show/NCT01702896
*  Interleukin-2 in Metastatic Melanoma - Full Text View - ClinicalTrials.gov
The purpose of this study is to determine whether Interleukin-2 at the dose and schedule used in this study will help to ... Interleukin-2. Antineoplastic Agents. Analgesics, Non-Narcotic. Analgesics. Sensory System Agents. Peripheral Nervous System ... Median survival of patients treated with this moderate dose bolus Interleukin-2 schedule. [ Time Frame: 9 weeks ]. ... Phase II Trial of Moderate Dose Bolus Interleukin-2 in Metastatic Melanoma. ...
  https://clinicaltrials.gov/ct2/show/study/NCT01702896?view=record
*  Interleukin-2 - UNM Comprehensive Cancer Center
Generic Name: Aldesleukin (al-des-LOO-kin), Interleukin-2, recombinant human interleukin 2, IL-2. Trade Name: Proleukin® ... Aldesleukin is similar in structure to a naturally occurring substance in the body, called interleukin-2. Aldesleukin produces ...
  http://cancer.unm.edu/2009/12/29/interleukin-2-2/
*  'receptors interleukin 2' Protocols and Video...
Receptors, Interleukin-2: Receptors present on activated T-Lymphocytes and B-Lymphocytes that are specific for Interleukin-2 ... They are heterotrimeric proteins consisting of the Interleukin-2 receptor alpha subunit, the Interleukin-2 receptor beta ...
  https://www.jove.com/keyword/receptors+interleukin+2
*  Computational design of interleukin-2 mimetics
Interleukin-2 is a cytokine that plays a central role in immune system homeostasis, exerting paradoxical immunostimulatory and ... For my work in this dissertation, I have computationally designed minimalist interleukin-2 mimetics that retain only the ...
  https://digital.lib.washington.edu/researchworks/handle/1773/33593
*  Interleukin-2 Treatment for Wiskott-Aldrich Syndrome
If IL-2 can circumvent a defective WASp to restore. NK cell function, the investigators will propose a larger NIH funded ... treat WAS subjects with IL-2 to determine safety and efficacy of IL-2 in this population and. if NK cell function is restored ... subject NK cells to IL-2 in vitro restores NK cell function and allows for normal F-actin. reorganization. Thus, the ... Reinstituting Natural Killer Cell Cytotoxicity and Cytoskeletal Dynamics in Wiskott-Aldrich Syndrome With IL-2 Therapy. Trial ...
  http://www.knowcancer.com/cancer-trials/NCT00774358/
*  Il2 - Interleukin-2 precursor - Rattus norvegicus (Rat) - Il2 gene & protein
interleukin-2 receptor binding Source: RGD ,p>Inferred from Mutant Phenotype,/p> ,p>Describes annotations that are concluded ... interleukin-2 receptor binding Source: RGD ,p>Inferred from Mutant Phenotype,/p> ,p>Describes annotations that are concluded ... positive regulation of interleukin-17 production Source: RGDInferred from sequence orthologyi*16482511 ... R-RNO-451927. Interleukin-2 family signaling. R-RNO-5673001. RAF/MAP kinase cascade. R-RNO-912526. Interleukin receptor SHC ...
  http://www.uniprot.org/uniprot/P17108
*  Cerebral Vasomotor Responses after Recombinant Interleukin 2 Infusion | Cancer Research
Cerebral Vasomotor Responses after Recombinant Interleukin 2 Infusion. Mary D. Ellison, Richard J. Krieg and Randall E. ... Cerebral Vasomotor Responses after Recombinant Interleukin 2 Infusion. Mary D. Ellison, Richard J. Krieg and Randall E. ... Cerebral Vasomotor Responses after Recombinant Interleukin 2 Infusion. Mary D. Ellison, Richard J. Krieg and Randall E. ... Cerebral Vasomotor Responses after Recombinant Interleukin 2 Infusion Message Subject (Your Name) has forwarded a page to you ...
  http://cancerres.aacrjournals.org/content/50/14/4377
*  Ultra Low Dose Interleukin-2 in Healthy Volunteers - Full Text View - ClinicalTrials.gov
Interleukin-2. IL-2. Stem Cells. Regulatory T Cells (T regs). Natural Killer Cells (NK cells). Healthy Volunteer. HV. ... Interleukin-2 is a drug that can help stimulate the body s response to inflammation. High dose interleukin-2 has been used to ... Interleukin 2 (IL-2, aldesleukin) was discovered as a T cell growth factor more than 30 years ago. IL-2 was the first human ... Very low dose interleukin-2 (700 folds less than regular dose) was previously tested in cancer patients and stem cell ...
  https://clinicaltrials.gov/ct2/show/NCT01445561
*  Interleukin-2 Therapy for HIV Infection - Supplemental Procedures - Full Text View - ClinicalTrials.gov
Interleukin-2 Therapy for HIV Infection - Supplemental Procedures. The safety and scientific validity of this study is the ... This study is designed as a randomized, open label trial to evaluate the effect of interleukin-2 (IL-2) on CD4 counts in ... Interleukin-2. Antimetabolites. Molecular Mechanisms of Pharmacological Action. Reverse Transcriptase Inhibitors. Nucleic Acid ... Certain patients who are participating in NIH protocols involving interleukin-2 (IL-2) therapy for HIV disease may be requested ...
  https://clinicaltrials.gov/show/NCT00001354?order=116
*  Effect of Interleukin-2 on HIV Treatment Interruption - Full Text View - ClinicalTrials.gov
Interleukin-2 (IL-2) helps the body make infection-fighting white blood cells, including CD4 and CD8 T cells. One HIV treatment ... Conrad A. Interleukin-2--where are we going? J Assoc Nurses AIDS Care. 2003 Nov-Dec;14(6):83-8. Review. ... Interleukin-2. Antineoplastic Agents. Analgesics, Non-Narcotic. Analgesics. Sensory System Agents. Peripheral Nervous System ... Xu J, Whitman L, Lori F, Lisziewicz J. Methods of using interleukin 2 to enhance HIV-specific immune responses. AIDS Res Hum ...
  https://clinicaltrials.gov/ct2/show/study/NCT00015704?view=record
*  Interleukin-2 in Treating Patients With Mycosis Fungoides - Full Text View - ClinicalTrials.gov
Interleukin-2 in Treating Patients With Mycosis Fungoides. The safety and scientific validity of this study is the ... Patients receive interleukin-2 (IL-2) subcutaneously on days 1-5 during weeks 1-3 and on days 1-3 and 5 during week 4. ... Interleukin-2. Antineoplastic Agents. Analgesics, Non-Narcotic. Analgesics. Sensory System Agents. Peripheral Nervous System ... RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. ...
  https://www.clinicaltrials.gov/ct2/show/NCT00002687
*  Transmembrane signalling by interleukin 2 | Biochemical Society Transactions
Transmembrane signalling by interleukin 2. Gordon B. Mills, Nan Zhang, Rosemarie Schmandt, Marion Fung, Warner Greene, Alan ... Transmembrane signalling by interleukin 2. Gordon B. Mills, Nan Zhang, Rosemarie Schmandt, Marion Fung, Warner Greene, Alan ... Transmembrane signalling by interleukin 2 Message Subject (Your Name) has forwarded a page to you from Biochemical Society ... Biochemical Society Transactions Apr 01, 1991, 19 (2) 277-287; DOI: 10.1042/bst0190277 ...
  http://www.biochemsoctrans.org/content/19/2/277
*  Interleukin-2 therapy for human cancer | Springer for Research & Development
Smith KA (1988) The bimolecular structure of the interleukin 2 receptor. Immunology Today 9:36-37PubMedCrossRefGoogle Scholar ... Interleukin-2 therapy Immune apparatus Lymphokine-activated killer cells Human cancer This is a preview of subscription content ... Stern JB, Smith KA (1986) Interleukin-2 induction of T-cell Gl progression and c-myb expression. Science 233:203-206PubMed ... Kornfeld H, Berman JS, Beer DJ, Center DM (1985) Induction of human T lymphocyte motility by interleukin-2. J Immunol 134:3887- ...
  https://rd.springer.com/article/10.1007/BF02718245
*  Human recombinant interleukin-2 as an experimental therapeutic. | Pharmacological Reviews
Human recombinant interleukin-2 as an experimental therapeutic. Message Subject (Your Name) has forwarded a page to you from ... Human recombinant interleukin-2 as an experimental therapeutic.. J L Winkelhake and S S Gauny ... Human recombinant interleukin-2 as an experimental therapeutic.. J L Winkelhake and S S Gauny ... Human recombinant interleukin-2 as an experimental therapeutic.. J L Winkelhake and S S Gauny ...
  http://pharmrev.aspetjournals.org/content/42/1/1
*  Interleukin-2 / IL2 antibody | acris-antibodies.com
Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen-activated T lymphocytes . Human IL-2 ( ... Background of Interleukin-2 / IL2 antibody. Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or ... This Interleukin-2 antibody stained formalin-fixed, paraffin-embedded sections of human breast invasive ductal carcinoma. The ... This Interleukin-2 antibody stained formalin-fixed, paraffin-embedded sections of human breast invasive ductal carcinoma. The ...
  https://www.acris-antibodies.com/target/interleukin-2-antibody-il2-antibody.htm