*  Interleukin 13 - wikidoc
Interleukin 13 (IL-13) is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells[1], that is an ... 2005). "Interleukin-13 in the skin and interferon-gamma in the liver are key players in immune protection in human ... Skinnider BF, Kapp U, Mak TW (2003). "The role of interleukin 13 in classical Hodgkin lymphoma.". Leuk. Lymphoma. 43 (6): 1203- ... IL-13 effector functions. Annu Rev Immunol. 2003;21:425-56. *↑ Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL ...
  http://wikidoc.org/index.php/Interleukin-13
*  Interleukin 13 - Wikipedia
Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located ... Interleukin-13 has a critical role in the Goblet cell metaplasia. Goblet cells are filled with mucin (MUC). MUC5AC Mucin 5AC is ... Interleukin-13 induces goblet cell differentiation and allows for the production of MUC5AC in tracheal epithelium. 15- ... Interleukin-13 receptor, the IL-13 receptor GRCm38: Ensembl release 89: ENSMUSG00000020383 - Ensembl, May 2017 "Human PubMed ...
  https://en.wikipedia.org/wiki/Interleukin_13
*  Interleukin-13 receptor - Wikipedia
Murata T, Obiri NI, Puri RK (1998). "Structure of and signal transduction through interleukin-4 and interleukin-13 receptors ( ... Chomarat P, Banchereau J (1998). "Interleukin-4 and interleukin-13: their similarities and discrepancies". Int. Rev. Immunol. ... The interleukin-13 receptor is a type I cytokine receptor, binding Interleukin-13. It consists of two subunits, encoded by ... Receptors, Interleukin-13 at the US National Library of Medicine Medical Subject Headings (MeSH). ...
  https://en.wikipedia.org/wiki/Interleukin-13_receptor
*  Il13 - Interleukin-13 precursor - Mus musculus (Mouse) - Il13 gene & protein
sp,P20109,IL13_MOUSE Interleukin-13 OS=Mus musculus OX=10090 GN=Il13 PE=2 SV=1 ... IPR020470. IL-13. IPR001325. IL-4/IL-13. IPR018096. IL-4/IL-13_CS. ... IPR020470. IL-13. IPR001325. IL-4/IL-13. IPR018096. IL-4/IL-13_CS. ... Belongs to the IL-4/IL-13 family.Curated. ,p>UniProtKB Keywords constitute a ,a href="http://www.uniprot.org/keywords"> ...
  http://www.uniprot.org/uniprot/P20109
*  Interleukin 13 receptor, alpha 1 - Wikipedia
Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. The ... Interleukin-13 receptor GRCh38: Ensembl release 89: ENSG00000131724 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... Orchansky PL, Kwan R, Lee F, Schrader JW (1999). "Characterization of the cytoplasmic domain of interleukin-13 receptor-alpha ... 2004). "Up-regulation of interleukin-13 receptor alpha1 on human keratinocytes in the skin of psoriasis and atopic dermatitis ...
  https://en.wikipedia.org/wiki/Interleukin_13_receptor,_alpha_1
*  Recombinant Human Interleukin-13 | Cell Sciences
Interleukin-13 (IL-13) is an important cytokine secreted from Th2 cells, mast cells and NK cells. IL-13 exerts anti- ... p,Recombinant Human IL-13 is a single, non-glycosylated polypeptide chain containing 115 amino acids.,/p, ,p,Background: ... Background: Interleukin-13 (IL-13) is an important cytokine secreted from Th2 cells, mast cells and NK cells. IL-13 exerts anti ... The receptor subunits of IL-13 consist of IL-4Rα, IL-13Rα1 and IL-13Rα2. Blocking of IL-13 activity inhibits the ...
  https://www.cellsciences.com/recombinant-human-interleukin-13
*  Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages
... Sarah E. Jackson, ... profound induction of leukotriene C4 synthase expression by interleukin 4," Journal of Experimental Medicine, vol. 193, no. 1, ... K. Espinosa, Y. Bossé, J. Stankova, and M. Rola-Pleszczynski, "CysLT1 receptor upregulation by TGF-β and IL-13 is associated ... M. Thivierge, J. Staňková, and M. Rola-Pleszczynski, "IL-13 and IL-4 up-regulate cysteinyl leukotriene 1 receptor expression in ...
  https://www.hindawi.com/journals/ja/2012/348741/ref/
*  Interleukin-13 / IL13 antibody | acris-antibodies.com
Interleukin-13 (IL-13) is a 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and ... Interleukin-13 (IL-13) is a 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and ... Formalin-Fixed, Paraffin-Embedded Rat Spleen stained with Interleukin-13 / IL13 Antibody Cat.-No AM20534AF-N at 10 µg/ml after ... This pattern is similar to the expression of Interleukin-4 (IL-4) but also includes subsets of Th1 and Th17 cells that do not ...
  https://www.acris-antibodies.com/target/interleukin-13-antibody-il13-antibody.htm?ab_ag_reactivity=Por
*  Interleukin-13 / IL13 - PP1034B2 | acris-antibodies.com
Interleukin-13 / IL13, 50 µg. Human IL13 was originally identified by differential screening of an anti CD28 activated human ... Interleukin-13 / IL13 (His-tagged). Not available. Human Purified >95.0% as determined by: (a) Analysis by RP-HPLC. (b) ... Interleukin-13 / IL13 (His-tagged). Not available. Human Purified >95.0% as determined by: (a) Analysis by RP-HPLC. (b) ... Interleukin-13 / IL13 (His-tagged). Not available. Human Purified >95.0% as determined by: (a) Analysis by RP-HPLC. (b) ...
  https://www.acris-antibodies.com/antibodies/primary-antibodies/interleukin-13-il13-pp1034b2.htm
*  Restoration of Tumor Immunosurveillance via Targeting of Interleukin-13 Receptor-α2 | Cancer Research
Restoration of Tumor Immunosurveillance via Targeting of Interleukin-13 Receptor-α2. Stefan Fichtner-Feigl, Masaki Terabe, ... Regulation and function of the interleukin 13 receptor α2 during a T helper cell type 2-dominant immune response. J Exp Med ... Restoration of Tumor Immunosurveillance via Targeting of Interleukin-13 Receptor-α2 Message Subject (Your Name) has forwarded a ... In previous studies, we described a "counter-immunosurveillance" mechanism initiated by tumor-activated, interleukin-13 (IL-13 ...
  http://cancerres.aacrjournals.org/content/68/9/3467
*  CiNii 論文 - STAT6 Mediates Apoptosis of Human Coronary Arterial Endothelial Cells by...
Costimulation with interleukin-4 and interleukin-10 induces mast cell apoptosis and cell cycle arrest : p53 and the ... Interleukin-4 cooperates with interleukin-10 to inhibit vascular permeability factor release by peripheral blood mononuclear ... Interleukin-13 protects endothelial cells from apoptosis and activation : association with the protective genes A20 and A1 ... Interleukin-4 elicits apoptosis of developing mast cells via a Stat6-dependent mitochondrial pathway BAILEY DP ...
  http://ci.nii.ac.jp/naid/10021934025
*  Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages
... Sarah E. Jackson, ... Interleukin (IL)-13 is a Th2 cytokine with well-established roles in promoting airway responsiveness, mucus secretion, and ... LTC4 synthase can be upregulated by cytokines, including interleukin (IL)-3 and IL-5 in maturing eosinophils [11] and IL-4 and ... We examined whether interleukin-13 can increase LTC4 synthase gene transcription and cysteinyl-leukotriene synthesis in ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3205618/?lang=en-ca
*  An Exploratory Study of the Effects of a Single Dose of QAX576 (an Interleukin-13 Monoclonal Antibody) on Simulated Hayfever -...
An Exploratory Study of the Effects of a Single Dose of QAX576 (an Interleukin-13 Monoclonal Antibody) on Simulated Hayfever. ... A Proof of Concept Study of the Effects of QAX576 (an Interleukin-13 Monoclonal Antibody) on Allergic Inflammation Following ... This study will investigate whether a single dose QAX576 (an interleukin-13 monoclonal antibody) gives protection against a ...
  https://clinicaltrials.gov/show/NCT00584584
*  Specifically targeted killing of interleukin-13 (IL-13) receptor-expressing breast cancer by IL-13 fusion cytotoxin in animal...
Structure of and signal transduction through interleukin-4 and interleukin-13 receptors. Int J Mol Med, 1998;1:551-7. ... interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for interleukins 2, ... Modulation of interleukin (IL)-13 binding and signaling by the γc chain of the IL-2 receptor. J Biol Chem, 1997;272:20251-8. ... Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells. J Exp Med, 1999;189:1939-45. ...
  http://mct.aacrjournals.org/content/3/2/137
*  Abstract 2663: SPECT/CT analysis of distribution of intracranially infused interleukin-13 Pseudomonas exotoxin, a targeted...
Interleukin-13 Pseudomonas exotoxin (IL-13PE), a powerful targeted agent for IL-13 receptor α2 (IL-13Rα2) - positive tumors is ... SPECT/CT analysis of distribution of intracranially infused interleukin-13 Pseudomonas exotoxin, a targeted agent for ... Abstract 2663: SPECT/CT analysis of distribution of intracranially infused interleukin-13 Pseudomonas exotoxin, a targeted ... Abstract 2663: SPECT/CT analysis of distribution of intracranially infused interleukin-13 Pseudomonas exotoxin, a targeted ...
  http://cancerres.aacrjournals.org/content/73/8_Supplement/2663
*  Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in Interleukin-13-induced minimal change-like nephropathy |...
Our established interleukin-13 ( IL-13 ) overexpression rat model of minimal change-like nephropathy provided a platform to ... Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in Interleukin-13-induced minimal change-like nephropathy ... Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in Interleukin-13-induced minimal change-like nephropathy ... Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in Interleukin-13-induced minimal change-like nephropathy ...
  http://www.clinsci.org/content/early/2016/10/05/CS20160312
*  Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells. - Semantic Scholar
The IL-13-enhanced response to UTP/ionomycin was sensitive to bumetanide and DIDS and was reduced in a low-chloride, ... Interleukin (IL)-13 has been associated with asthma, allergic rhinitis, and chronic sinusitis, all conditions where an ... The results indicate that IL-13 converts the human bronchial epithelium from an absorptive to a secretory phenotype that is the ... We have investigated the effects of IL-13 on the ion transport characteristics of human bronchial epithelial cells cultured at ...
  https://www.semanticscholar.org/paper/Interleukin-13-induces-a-hypersecretory-ion-in-Danahay-Atherton/40b14aa52780306a934b4b8a7d1dd54ae09f3fef
*  Interleukin-13 initiates signal transduction through IL-13Rα2 in human glioma cell lines via AP-1 pathway | NIH Research...
Interleukin-13 initiates signal transduction through IL-13Rα2 in human glioma cell lines via AP-1 pathway. Wednesday, September ... Previously, we have demonstrated that Interleukin 13 (IL-13) receptor alpha-2 (α2) is overexpressed in approximately 78% of GBM ... However, the regulation of the IL-13/IL-13R axis is not understood completely and it is not clear whether IL-13 receptors are ... We have also shown that IL-13 receptors (IL-13R) can be targeted by IL-13-Pseudomonas exotoxin for cancer therapy in pre- ...
  https://researchfestival.nih.gov/2016/posters/interleukin-13-initiates-signal-transduction-through-il-13ra2-human-glioma
*  Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance. - Semantic Scholar
IL-4 and IL-13 activate the type 2 IL-4 receptor (IL-4R), which contains the IL-13Rα1 and IL-4Rα chains. We used mice deficient ... Nematode infection upregulates interleukin-4 (IL-4) and IL-13 and induces STAT6-dependent changes in gut function that promote ... Notably, the contribution of claudin-2, which has been linked to IL-13, does not mediate the increased mucosal permeability ... in IL-13Rα1 (IL-13Rα1(-/-)) to examine the contribution of IL-13 acting at the type 2 IL-4R to immune and functional responses ...
  https://www.semanticscholar.org/paper/Interleukin-13-Receptor-%CE%B11-Dependent-Responses-in-Sun-Urban/4788df1ea6d16e19888fce6b30d73086885d56e2
*  Association of -1112 C/T Promoter Region Polymorphism of the Interleukin 13 Gene with Occurrence of Colorectal Cancer
... of the interleukin-13 gene.,/p,,p,,bold,Material and methods.,/bold, The study group comprised 150 cancer patients and 170 ... IL-13,/italic, gene with the clinical characteristics of colorectal cancer patients. We observed no association between the ... IL-13,/italic, gene polymorphism (-1112 C/T) and colorectal cancer risk in the Polish population.,/p,,/p, ... Association of -1112 C/T Promoter Region Polymorphism of the Interleukin 13 Gene with Occurrence of Colorectal Cancer ...
  https://www.infona.pl/resource/bwmeta1.element.-psjd-doi-10_2478_v10035-011-0004-x
*  Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. - PubMed - NCBI
Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which ... Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.. LaPorte SL1, Juo ZS, ... Molecular and structural basis of cytokine receptor pleiotropy in the Interleukin-4/13 system ... Molecular and structural basis of cytokine receptor pleiotropy in the Interleukin-4/13 system ...
  https://www.ncbi.nlm.nih.gov/pubmed/18243101
*  The effect of interleukin-13 (IL-13) and interferon-γ (IFN-γ) on expression of surfactant proteins in adult human alveolar type...
Wills-Karp M, Chiaramonte M: Interleukin-13 in asthma. Curr Opin Pulm Med 2003, 9:21-27.View ArticlePubMedGoogle Scholar. ... The effect of interleukin-13 (IL-13) and interferon-γ (IFN-γ) on expression of surfactant proteins in adult human alveolar type ... Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA: Pulmonary expression of interleukin-13 causes inflammation ... Hancock A, Armstrong L, Gama R, Millar A: Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung. ...
  https://respiratory-research.biomedcentral.com/articles/10.1186/1465-9921-11-157
*  Enhanced Interleukin (IL)-13 Responses in Mice Lacking IL-13 Receptor α 2 | JEM
Enhanced Interleukin (IL)-13 Responses in Mice Lacking IL-13 Receptor α 2. Nancy Wood, Matthew J. Whitters, Bruce A. Jacobson, ... Interleukin-13 receptor alpha′ but not alpha chain: a functional component of interleukin-4 receptors. Blood. 91:3884-3891. ... Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc. Natl. Acad ... Interleukin (IL)-13 has recently been shown to play important and unique roles in asthma, parasite immunity, and tumor ...
  http://jem.rupress.org/content/197/6/703
*  Expression, charakterization and biological functions of interleukin-4/interleukin-13 receptor complexes in different cell...
Expression, charakterization and biological functions of interleukin-4/interleukin-13 receptor complexes in different cell ... INTERLEUKIN RECEPTORS (IMMUNOLOGY); MONOCYTES, BLOOD MACROPHAGES, MONONUCLEAR BLOOD CELLS; MAST CELLS (IMMUNOLOGY); CANCER ...
  https://www.research-collection.ethz.ch/handle/20.500.11850/142919
*  DESIGN AND SELECTION OF MEDICAMENTS THAT MODULATE THE FUNCTION AND ACTIVITY OF INTERLEUKIN 13 - diagram, schematic, and...
Back to DESIGN AND SELECTION OF MEDICAMENTS THAT MODULATE THE FUNCTION AND ACTIVITY OF INTERLEUKIN 13 , All Patents . ... DESIGN AND SELECTION OF MEDICAMENTS THAT MODULATE THE FUNCTION AND ACTIVITY OF INTERLEUKIN 13 - diagram, schematic, and image ...
  http://www.patentsencyclopedia.com/imgfull/20130281318_09