Loading...
*  Reactome | LUM (lumican) binds integrin alpha2beta1
Integrin cell surface interactions (Gallus gallus) * LUM (lumican) binds integrin alpha2beta1 (Gallus gallus) ...
  http://www.reactome.org/content/detail/R-GGA-4085133
*  Reactome | Collagen type VII binds integrin alpha2beta1
Integrin cell surface interactions (Mus musculus) * Collagen type VII binds integrin alpha2beta1 (Mus musculus) ...
  http://www.reactome.org/content/detail/R-MMU-4086216
*  Reactome | Endorepellin binds alpha2beta1 integrin
Integrin cell surface interactions (Gallus gallus) * Endorepellin binds alpha2beta1 integrin (Gallus gallus) ...
  http://www.reactome.org/content/detail/R-GGA-4088220
*  Leukotriene D(4)-induced adhesion of Caco-2 cells is mediated by prostaglandin E(2) and upregulation of alpha2beta1-integrin.
... ... and upregulation of alpha2beta1-integrin.}, url = {http://dx.doi.org/10.1016/S0014-4827(03)00285-4}, volume = {289}, year = { ...
  https://lup.lub.lu.se/search/publication/117754
*  Reactome | Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1
Integrin cell surface interactions (Bos taurus) * Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and ... Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 Stable Identifier ... Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Bos taurus) ... Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Homo sapiens) ...
  http://www.reactome.org/content/detail/R-BTA-2327695
*  Copine | SpringerLink
Structural basis of collagen recognition by integrin alpha2beta1. Cell. 2000;101:47-56.PubMedCrossRefGoogle Scholar ... Lee JO, Rieu P, Arnaout MA, Liddington R. Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18 ...
  https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-67199-4_56
*  Expression of LYN in cancer - Summary - The Human Protein Atlas
GO:0034666 [integrin alpha2-beta1 complex]. GO:0035556 [intracellular signal transduction]. GO:0038083 [peptidyl-tyrosine ... GO:0005178 [integrin binding]. GO:0005515 [protein binding]. GO:0005524 [ATP binding]. GO:0005634 [nucleus]. GO:0005737 [ ... GO:0033628 [regulation of cell adhesion mediated by integrin]. GO:0034136 [negative regulation of toll-like receptor 2 ... GO:0033628 [regulation of cell adhesion mediated by integrin]. GO:0034136 [negative regulation of toll-like receptor 2 ...
  http://www.proteinatlas.org/ENSG00000254087-LYN/pathology
*  Platelet - Wikipedia
Platelet GP1b-IX-V receptor binds with VWF; and GPVI receptor and integrin alpha2beta1 bind with collagen.[32] ...
  https://en.m.wikipedia.org/wiki/Platelet
*  3D quantitative analyses of angiogenic sprout growth dynamics - Shirinifard - 2013 - Developmental Dynamics - Wiley Online...
A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. Am J Pathol 175:1338-1347. *CrossRef , ...
  http://onlinelibrary.wiley.com/doi/10.1002/dvdy.23946/full
*  CHAD Gene - GeneCards | CHAD Protein | CHAD Antibody
Integrin alpha2beta1 is a receptor for the cartilage matrix protein chondroadherin. (PMID: 9281592) Camper L … Lundgren- ... This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important ... This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=CHAD
*  Reactome | Collagen type VII -NC2 trimer [extracellular region]
Integrin cell surface interactions (Homo sapiens) * Collagen type VII binds integrin alpha2beta1 (Homo sapiens) * Collagen type ... Collagen type VII fibril:Integrin alpha2beta1 [plasma membrane] (Homo sapiens) * Collagen type VII fibril [extracellular region ...
  https://reactome.org/content/detail/R-HSA-2214323
*  Reactome | GalHyl-COL7A1(17-2821) [extracellular region]
Integrin cell surface interactions (Homo sapiens) * Collagen type VII binds integrin alpha2beta1 (Homo sapiens) * Collagen type ... Collagen type VII fibril:Integrin alpha2beta1 [plasma membrane] (Homo sapiens) * Collagen type VII fibril [extracellular region ...
  https://reactome.org/content/detail/R-HSA-3605702
*  Biological role of prolyl 3-hydroxylation in type IV collagen | PNAS
2003) Collagen platelet receptor polymorphisms integrin alpha2beta1 C807T and GPVI Q317L and risk of ischemic stroke. J Thromb ... Although integrin α2β1 could potentially be involved in the lethality of the P3H2-null embryos, its known binding sites do not ... Two receptors are known to be responsible for the initiation of collagen-induced platelet aggregation: GPVI and integrin α2β1. ...
  http://www.pnas.org/content/111/1/161
*  Vascular thiol isomerases | Blood Journal
Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1. Blood 2003; ... The role of protein disulfide isomerase in the post-ligation phase of β3 integrin-dependent cell adhesion. Thromb Res 2015;136( ... Disulfide Bonds as Regulators of Integrin Function in Thrombosis and Hemostasis. Antioxid Redox Signal 2016;24(1):16-31. ... Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins. Blood 2012;120(3 ...
  http://www.bloodjournal.org/content/128/7/893?sso-checked=true
*  The proteome maps of control and SB-treated platelets.A | Open-i
Integrin alpha2beta1/metabolism. *Male. *Models, Biological. *Platelet Adhesiveness/drug effects. *Platelet Aggregation/drug ... Conclusions/significance: Integrin α2β1 might be one of the direct target proteins of SB in platelets. The signal cascades ... Conclusions/significance: Integrin α2β1 might be one of the direct target proteins of SB in platelets. The signal cascades ... To certify the predicted network, binding affinity of SB to integrin α2β1 was checked in vitro and ex vivo in platelets. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3040754_pone.0014692.g002&req=4
*  Reactome | Collagen type XXVII fibre [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens) * Collagen, laminin, ...
  https://reactome.org/content/detail/R-HSA-2214301
*  Reactome | GlcGalHyl-COL1A2 [extracellular region]
Integrins alpha1beta1, alpha2beta1:Collagen type I fibril:Mg2+ [plasma membrane] (Homo sapiens) * Collagen type I fibril [ ... Integrins alpha1beta1, alpha2beta1:Collagen type I fibril:Mg2+ [plasma membrane] (Homo sapiens) * Collagen type I fibril [ ... Integrin cell surface interactions (Homo sapiens) * Collagen type I binds integrin alpha11beta1 (Homo sapiens) * Collagen type ... Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens) * Collagen, laminin, ...
  https://reactome.org/content/detail/R-HSA-2089984
*  Reactome | Laminin-211 [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens) * Collagen, laminin, ... Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Homo sapiens) * Integrin alpha6beta1:Laminin-211, 221, 332, ... Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Homo sapiens) * Integrin alpha7beta1:Laminin-211, 221, 411, 512, ... Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) (Homo sapiens) * Integrin alpha3beta1, alpha6beta4: ...
  https://reactome.org/content/detail/R-HSA-216003
*  Reactome | GlcGalHyl-COL2A1(182-1241) [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens) * Collagen, laminin, ... Integrin cell surface interactions (Homo sapiens) * Collagen type II binds integrin alpha10beta1 (Homo sapiens) * Collagen type ... Collagen type II binds integrin alpha2beta1, alpha1beta1, alpha11beta1 (Homo sapiens) * Collagen type II fibril [extracellular ... Collagen type II fibril:Integrins alpha2beta1, alpha1beta1, alpha11beta1 [plasma membrane] (Homo sapiens) * Collagen type II ...
  http://www.reactome.org/content/detail/R-HSA-2127330
*  Interactions between extracellular matrix and growth factors in wound healing - Schultz - 2009 - Wound Repair and Regeneration ...
... regulation through alpha1beta1 and alpha2beta1 integrins. Proc Natl Acad Sci USA 1997; 94: 13612-7. ... Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994; 264: 569-71. ... Boudreau NJ, Jones PL. Extracellular matrix and integrin signalling: the shape of things to come. Biochem J 1999; 339 (Part 3) ... Drake CJ, Davis LA, Little CD. Antibodies to beta 1-integrins cause alterations of aortic vasculogenesis, in vivo. Dev Dyn 1992 ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1524-475X.2009.00466.x/references
*  Reactome | Collagen alpha-1(II) chains [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Xenopus tropicalis) * Collagen, laminin, ... Integrin cell surface interactions (Xenopus tropicalis) * Collagen type II binds integrin alpha10beta1 (Xenopus tropicalis) * ... Non-integrin membrane-ECM interactions (Xenopus tropicalis) * DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Xenopus ... Integrin alpha10beta1:Collagen type II fibril:Mg2+ [plasma membrane] (Xenopus tropicalis) * Collagen type II fibril [ ...
  http://www.reactome.org/content/detail/R-XTR-2127295
*  Plus it
2009) The integrin alpha2beta1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-κB translocation and ... 2013) Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of beta1 integrins. ...
  http://www.jneurosci.org/content/34/35/11812
*  CiNii 論文 - 血小板における接着分子の信号伝達
Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and ... Identification in collagen type I of an integrin α_2β_1-binding site containing an essential GER sequence KNIGHT C. G. ... Integrin αIIbβ3-dependent calcium signals regulate platelet-fibrinogen interactions under flow : Involvement of PLCγ2 GONCALVES ... Coordinate interactions of Csk, Src, and Syk kinases with αIIbβ 3 initiate integrin signaling to the cytoskeleton OBERGFELL A ...
  https://ci.nii.ac.jp/naid/10021258207
*  Mechanisms Regulating Increased Production of Osteoprotegerin by Osteoblasts Cultured on Microstructured Titanium Surfaces
The small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3. Blood. 2006; ... Integrin signaling clearly plays a major role. Expression of α2 and β1 integrin subunits increases when osteoblasts are grown ... Requirement for α2β1 Integrin Signaling. To determine if signaling via the α2 integrin subunit was required for OPG expression ... α2β1 silenced cells exhibited a 70% reduction in the α2 integrin subunit and a 65% reduction in the β1 integrin subunit, based ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2700751/
*  Reactome | 3x4Hyp-3Hyp-GlcGalHyl-COL2A1(182-1241) [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Danio rerio) * Collagen, laminin, ... Integrin cell surface interactions (Danio rerio) * Collagen type II binds integrin alpha10beta1 (Danio rerio) * Collagen type ... Non-integrin membrane-ECM interactions (Danio rerio) * DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Danio rerio) * ... Integrin alpha10beta1:Collagen type II fibril:Mg2+ [plasma membrane] (Danio rerio) * Collagen type II fibril [extracellular ...
  http://www.reactome.org/content/detail/R-DRE-2127431