*  Reactome | LUM (lumican) binds integrin alpha2beta1
Integrin cell surface interactions (Gallus gallus) * LUM (lumican) binds integrin alpha2beta1 (Gallus gallus) ...
  http://www.reactome.org/content/detail/R-GGA-4085133
*  Reactome | Collagen type VII binds integrin alpha2beta1
Integrin cell surface interactions (Mus musculus) * Collagen type VII binds integrin alpha2beta1 (Mus musculus) ...
  http://www.reactome.org/content/detail/R-MMU-4086216
*  Reactome | Endorepellin binds alpha2beta1 integrin
Integrin cell surface interactions (Gallus gallus) * Endorepellin binds alpha2beta1 integrin (Gallus gallus) ...
  http://www.reactome.org/content/detail/R-GGA-4088220
*  Leukotriene D(4)-induced adhesion of Caco-2 cells is mediated by prostaglandin E(2) and upregulation of alpha2beta1-integrin.
... ... and upregulation of alpha2beta1-integrin.}, url = {http://dx.doi.org/10.1016/S0014-4827(03)00285-4}, volume = {289}, year = { ...
  https://lup.lub.lu.se/search/publication/117754
*  Reactome | Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1
Integrin cell surface interactions (Bos taurus) * Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and ... Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 Stable Identifier ... Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Bos taurus) ... Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Homo sapiens) ...
  http://www.reactome.org/content/detail/R-BTA-2327695
*  Expression of LYN in cancer - Summary - The Human Protein Atlas
GO:0034666 [integrin alpha2-beta1 complex]. GO:0035556 [intracellular signal transduction]. GO:0038083 [peptidyl-tyrosine ... GO:0005178 [integrin binding]. GO:0005515 [protein binding]. GO:0005524 [ATP binding]. GO:0005634 [nucleus]. GO:0005737 [ ... GO:0033628 [regulation of cell adhesion mediated by integrin]. GO:0034136 [negative regulation of toll-like receptor 2 ... GO:0033628 [regulation of cell adhesion mediated by integrin]. GO:0034136 [negative regulation of toll-like receptor 2 ...
  http://www.proteinatlas.org/ENSG00000254087-LYN/pathology
*  Platelet - Wikipedia
Platelet GP1b-IX-V receptor binds with VWF; and GPVI receptor and integrin alpha2beta1 bind with collagen.[32] ...
  https://en.m.wikipedia.org/wiki/Platelet
*  3D quantitative analyses of angiogenic sprout growth dynamics - Shirinifard - 2013 - Developmental Dynamics - Wiley Online...
A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. Am J Pathol 175:1338-1347. *CrossRef , ...
  http://onlinelibrary.wiley.com/doi/10.1002/dvdy.23946/full
*  CHAD Gene - GeneCards | CHAD Protein | CHAD Antibody
Integrin alpha2beta1 is a receptor for the cartilage matrix protein chondroadherin. (PMID: 9281592) Camper L … Lundgren- ... This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important ... This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=CHAD
*  Reactome | Collagen type VII -NC2 trimer [extracellular region]
Integrin cell surface interactions (Homo sapiens) * Collagen type VII binds integrin alpha2beta1 (Homo sapiens) * Collagen type ... Collagen type VII fibril:Integrin alpha2beta1 [plasma membrane] (Homo sapiens) * Collagen type VII fibril [extracellular region ...
  https://reactome.org/content/detail/R-HSA-2214323
*  The proteome maps of control and SB-treated platelets.A | Open-i
Integrin alpha2beta1/metabolism. *Male. *Models, Biological. *Platelet Adhesiveness/drug effects. *Platelet Aggregation/drug ... Conclusions/significance: Integrin α2β1 might be one of the direct target proteins of SB in platelets. The signal cascades ... Conclusions/significance: Integrin α2β1 might be one of the direct target proteins of SB in platelets. The signal cascades ... To certify the predicted network, binding affinity of SB to integrin α2β1 was checked in vitro and ex vivo in platelets. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3040754_pone.0014692.g002&req=4
*  Reactome | Collagen type XXVII fibre [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens) * Collagen, laminin, ...
  https://reactome.org/content/detail/R-HSA-2214301
*  Interactions between extracellular matrix and growth factors in wound healing - Schultz - 2009 - Wound Repair and Regeneration ...
... regulation through alpha1beta1 and alpha2beta1 integrins. Proc Natl Acad Sci USA 1997; 94: 13612-7. ... Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994; 264: 569-71. ... Boudreau NJ, Jones PL. Extracellular matrix and integrin signalling: the shape of things to come. Biochem J 1999; 339 (Part 3) ... Drake CJ, Davis LA, Little CD. Antibodies to beta 1-integrins cause alterations of aortic vasculogenesis, in vivo. Dev Dyn 1992 ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1524-475X.2009.00466.x/references
*  Plus it
2009) The integrin alpha2beta1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-κB translocation and ... 2013) Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of beta1 integrins. ...
  http://www.jneurosci.org/content/34/35/11812
*  CiNii 論文 - 血小板における接着分子の信号伝達
Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and ... Identification in collagen type I of an integrin α_2β_1-binding site containing an essential GER sequence KNIGHT C. G. ... Integrin αIIbβ3-dependent calcium signals regulate platelet-fibrinogen interactions under flow : Involvement of PLCγ2 GONCALVES ... Coordinate interactions of Csk, Src, and Syk kinases with αIIbβ 3 initiate integrin signaling to the cytoskeleton OBERGFELL A ...
  https://ci.nii.ac.jp/naid/10021258207
*  Mechanisms Regulating Increased Production of Osteoprotegerin by Osteoblasts Cultured on Microstructured Titanium Surfaces
The small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3. Blood. 2006; ... Integrin signaling clearly plays a major role. Expression of α2 and β1 integrin subunits increases when osteoblasts are grown ... Requirement for α2β1 Integrin Signaling. To determine if signaling via the α2 integrin subunit was required for OPG expression ... α2β1 silenced cells exhibited a 70% reduction in the α2 integrin subunit and a 65% reduction in the β1 integrin subunit, based ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2700751/
*  Reactome | 3x4Hyp-GlcGalHyl-COL2A1(182-1241) [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens) * Collagen, laminin, ... Integrin cell surface interactions (Homo sapiens) * Collagen type II binds integrin alpha10beta1 (Homo sapiens) * Collagen type ... Collagen type II binds integrin alpha2beta1, alpha1beta1, alpha11beta1 (Homo sapiens) * Collagen type II fibril [extracellular ... Collagen type II fibril:Integrins alpha2beta1, alpha1beta1, alpha11beta1 [plasma membrane] (Homo sapiens) * Collagen type II ...
  http://www.reactome.org/content/detail/2127366
*  Reactome | 3x4Hyp-3Hyp-GlcGalHyl-COL2A1(182-1241) [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Danio rerio) * Collagen, laminin, ... Integrin cell surface interactions (Danio rerio) * Collagen type II binds integrin alpha10beta1 (Danio rerio) * Collagen type ... Non-integrin membrane-ECM interactions (Danio rerio) * DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Danio rerio) * ... Integrin alpha10beta1:Collagen type II fibril:Mg2+ [plasma membrane] (Danio rerio) * Collagen type II fibril [extracellular ...
  http://www.reactome.org/content/detail/R-DRE-2127431
*  Platelet Adhesion to Collagen and Collagen-Related Peptide Under Flow | Arteriosclerosis, Thrombosis, and Vascular Biology
Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLC ... Evidence against a direct role of the integrin alpha2beta1 in collagen-induced tyrosine phosphorylation in human platelets. Eur ... Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen. EMBO J. 2001; 20: 2120-2130. ... β1 integrin function with similar kinetics and efficiency as wild-type platelets, indicating that the integrin receptor is not ...
  http://atvb.ahajournals.org/content/23/10/1934
*  Collagen, type XXIII, alpha 1 - Wikipedia
... novel ligand for integrin alpha2beta1 in the epidermis". J. Biol. Chem. 286 (31): 27804-13. doi:10.1074/jbc.M111.220046. PMC ... Integrin α2β1 is a collagen-binding integrin present at the epidermis, therefore this is the location where the interaction ... Cellular receptors for collagens belong to the family of β1 integrins. Collagen XXIII interacts in an ion-and conformation- ... Collagen Protein domain Transmembrane protein Non-small-cell lung carcinoma Prostate cancer Homotrimer Lipid raft Integrin, ...
  https://en.wikipedia.org/wiki/Collagen,_type_XXIII,_alpha_1
*  Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase β, and Not Via CD40 and IκB Kinase αSignificance |...
Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen. EMBO J. 2001;20:2120-2130. ... Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ... Agonist-induced integrin activation and secretion by Apoe−/− platelets lacking CD40 or CD40L. Washed platelets from Apoe−/−, ... CD40L stabilizes arterial thrombi by a beta3 integrin-dependent mechanism. Nat Med. 2002;8:247-252. doi: 10.1038/nm0302-247.. ...
  http://atvb.ahajournals.org/content/35/6/1374
*  A 3′-Untranslated Region (3′UTR) Induces Organ Adhesion by Regulating miR-199a* Functions
Revealing early steps of alpha2beta1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy. Mol ... Friedrichs J, Manninen A, Muller DJ, Helenius J. Galectin-3 regulates integrin alpha2beta1-mediated adhesion to collagen-I and ... beta 1-Integrin-mediated glioma cell adhesion and free radical-induced apoptosis are regulated by binding to a C-terminal ... Fibronectin is an extracellular glycoprotein which binds to integrins and mediates cell adhesion, proliferation, tissue ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2638016/
*  Laminin, gamma 3 - Wikipedia
Their adhesion to laminin-5 involves multiple receptors among which is integrin alpha2beta1". J. Cell Sci. 111 (14): 1993-2004 ... 2008). "Laminin Isoforms Containing the γ3 Chain Are Unable to Bind to Integrins due to the Absence of the Glutamic Acid ... 2002). "Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3)". Clin. Exp. ... Wilhelmsen K, Litjens SH, Sonnenberg A (2006). "Multiple Functions of the Integrin α6β4 in Epidermal Homeostasis and ...
  https://en.wikipedia.org/wiki/Laminin,_gamma_3
*  Equipe 6
Alpha2beta1 integrin controls association of Rac with the membrane and triggers quiescence of endothelial cells. Cailleteau L, ... Laminin-binding integrins induce Dll4 expression and Notch signaling in endothelial cells. Estrach S, Cailleteau L, Franco CA, ...
  http://www.unice.fr/c3m/EN/Equipe6.html