*  Inhaled insulin is associated with prolonged enhancement of glucose disposal in muscle and liver in the canine. - Semantic...
In dogs, insulin action in muscle is enhanced for as long as 3 h after insulin inhalation. This study was designed to determine ... Inhalation of insulin was associated with greater than expected (based on insulin levels) glucose disposal. This may explain ... Human insulin was administered via inhalation (Exubera; n = 9) or infusion (Humulin R; n = 9) in dogs using an infusion ... Somatostatin was infused to prevent insulin secretion, and glucagon was infused to replace basal plasma levels of the hormone. ...
  https://www.semanticscholar.org/paper/Inhaled-insulin-is-associated-with-prolonged-enhan-Edgerton-Cherrington/25361171399764cda8a42ef03c501dc2456a24ae
*  Patent US20050187142 - Zinc-free and low-zinc insulin preparations having improved stability - Google Patents
... an insulin metabolite, an insulin analog, and an insulin derivative; at least one surfactant; optionally at least one ... The invention also relates to the production of such insulin preparations and their use as pharmaceutical formulations. ... The invention relates to a formulation comprising a polypeptide selected from at least one of insulin, ... human insulin, bovine insulin, or porcine insulin, or another animal insulin), an insulin analog, an insulin derivative, and ...
  http://www.google.com/patents/US20050187142?dq=5,832,511
*  Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus - Full Text View - ClinicalTrials.gov
Insulin resistance is characterized by an impaired response to the physiologic effects of insulin and leads to decreased ... Therefore in the insulin-resistant state, blood glucose and insulin levels are increased. The relationship between improved ... Change from baseline in Insulin [ Time Frame: Weeks 4, 8, and 12 or Final Visit. ]. *Change from baseline in Proinsulin/insulin ... Combination oral therapy and eventually insulin are usually required to maintain lower blood glucose levels but can result in ...
  https://clinicaltrials.gov/ct2/show/study/NCT00760344?show_locs=Y
*  Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance and...
WP4 - Severe Insulin-Deficient Diabetes (SIDD) - mechanisms & pathways. *WP5 - Severe Insulin-Resistant Diabetes (SIRD) - ... Mechanisms of Defective Insulin Secretion in Type 2 Diabetes. *NFAT signaling in chronic and acute inflammation. A novel target ... Coupling mechanisms of insulin secretion - roles of mitochondrial metabolism and cAMP. *Lipid metabolism in the pancreatic beta ... Also, the insulin secretory response to intravenous glucagon-like peptide 1 was reduced in vivo. Similarly, islets stimulated ...
  https://www.ludc.lu.se/eva-degerman-pi/publication/5c964935-3efc-480b-a55c-f0bf6347a2a8
*  Snails' speedy insulin | UNews
Putting snail insulin to work. Studying the structure of the cone snail insulin could help researchers modify human insulin to ... Tests on insulin receptors in the lab showed that although the snail insulin was less effective than human insulin, it was ... Human insulin is a hormone that is produced in the pancreas and secreted to aid in the body's uptake of glucose. The insulin ... It's how insulin is stored in the pancreas. But injected insulin must de-aggregate into individual molecules before doing a ...
  https://unews.utah.edu/snails-speedy-insulin/
*  Market Study - Global Human Insulin Market Size, Share, Growth, Trends and Forecast To 2020: Acute Market Reports - Get News
Modern human insulin by type - long action human insulin, rapid acting human insulin and premixed human insulin. North America ... Traditional human insulin by type - short acting human insulin, intermediate acting human insulin and premixed human insulin. ... Modern human insulin - long action human insulin, rapid acting human insulin and premixed human insulin. Canada market ... Traditional human insulin - short acting human insulin, intermediate acting human insulin and premixed human insulin. Modern ...
  http://www.getnews.info/513607/market-study-global-human-insulin-market-size-share-growth-trends-and-forecast-to-2020-acute-market-reports.html
*  Patent US7021309 - Method of use of monomeric insulin as a means for improving the ... - Google Patents
Particles of insulin and in particular monomeric insulin delivered to the surface of lung tissue will be absorbed into the ... The monomeric insulin may be a dry powder but is preferably in a liquid formulation delivered to the patient from a hand-held, ... Further, the rate at which blood glucose is lowered is increased by the use of monomeric insulin. ... The need for the delivery of insulin by injection can be reduced or eliminated by delivering an aerosolized monomeric insulin ...
  http://www.google.com/patents/US7021309?dq=6,243,373
*  Moderate calorie restriction to achieve normal weight reverses β-cell dysfunction in diet-induced obese mice: involvement of...
Effects of CR on glucose tolerance, insulin sensitivity, insulin secretion and insulin content. As shown in Fig. 4a, b and ... Glucose-stimulated insulin secretion and insulin content measurements. Static glucose-stimulated insulin secretion (GSIS) ... Effects of CR on glucose-stimulated insulin secretion and insulin content in isolated islets. a glucose-stimulated insulin ... NC CR islets showed the lowest insulin content and basal insulin secretion, however, high glucose-stimulated insulin secretion ...
  https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-015-0028-z
*  Insulin Treatment Reverses the Insulin Resistance of Type II Diabetes Mellitus | Diabetes Care
Type II diabetic subjects are both insulin-deficient and insulin-resistant. Recent studies suggest that the insulin resistance ... Insulin Treatment Reverses the Insulin Resistance of Type II Diabetes Mellitus. J A Scarlett, R S Gray, J Griffin, J M Olefsky ... Insulin Treatment Reverses the Insulin Resistance of Type II Diabetes Mellitus. J A Scarlett, R S Gray, J Griffin, J M Olefsky ... Insulin Treatment Reverses the Insulin Resistance of Type II Diabetes Mellitus Message Subject (Your Name) has forwarded a page ...
  http://care.diabetesjournals.org/content/5/4/353
*  Insulin (Parenteral Route) Side Effects - Mayo Clinic
... of insulin is measured in USP Insulin Units and USP Insulin Human Units and is usually expressed in terms such as U-100 insulin ... Another type of insulin that you may use is called human insulin. It is just like the insulin made by humans but it is made by ... For isophane insulin human/insulin human (NPH/R)-Human isophane/human regular insulin. * For injection dosage form: * For ... Insulin is drawn up into the spray device from an insulin bottle. Pressing a button forcefully sprays the insulin dose into the ...
  http://www.mayoclinic.org/drugs-supplements/insulin-parenteral-route/side-effects/drg-20069501?p=1
*  9 Diabetes Statistics and Basal Insulin Facts That May Surprise You
Basal insulin facts. Basal insulin is the insulin that works in the background between meals and overnight. This means it's the ... amount of insulin is given to cover meals. Using the insulin pump is a good way to adjust the basal insulin levels in a very ... long-acting insulin is injected once or twice a day to mimic basal insulin. Those with type 1 would then take insulin to cover ... Ask the Expert: Basal Insulin Therapy for Type 2 Diabetes. Ask the Expert: Basal Insulin Therapy for Type 2 Diabetes. Get the ...
  https://www.drugs.com/health/diabetes-basal-insulin/statistics-3402/
*  IP] remaining insulin
But is it , , really? When calculating "insulin on board" does one really want to estimate , , insulin _activity_ or insulin ... The Minimed uses a scale , , that approximates insulin activity based on manufacturer data (90% of the , , insulin activity ... insulin-pumpers.org *Follow-Ups: *[IP] Re remaining insulin *From: Liz Davis ,email @ redacted, ... perhaps the insulin absorption does, and, therefore, perhaps the Cozmo method , , is superior for calculating "insulin on board ...
  http://www.insulin-pumpers.org/mail/archive/mail-insulin-pumpers/Sep2003/msg00864.html
*  Improved insulin-sensitivity in mice heterozygous for PPAR-gamma defi" by P D. Miles, Y Barak et al.
Likewise, the insulin-induced suppression of hepatic glucose production was significantly greater in the PPAR-gamma(+/-) mice ... Nor was there a difference in glucose excursion between the groups of mice during oral glucose tolerance test, but insulin ... PPAR-gamma improves insulin sensitivity, a similar effect is obtained by genetically reducing the expression levels of the ... To gain insight into the role of this nuclear receptor in insulin resistance and diabetes, we conducted metabolic studies in ...
  https://mouseion.jax.org/stfb2000_2009/162/
*  Prediabetes & Insulin Resistance | NIDDK
Defines insulin resistance and prediabetes and describes diagnosis. Lists ways to treat these conditions to help avoid ... Prediabetes & Insulin Resistance. What is insulin?. Insulin is a hormone made in the pancreas, an organ located behind the ... What happens with insulin resistance?. In insulin resistance, muscle, fat, and liver cells do not respond properly to insulin ... Insulin's Role in Blood Glucose Control. When blood glucose levels rise after a meal, the pancreas releases insulin into the ...
  https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance
*  Pancreatic Islet Transplantation | NIDDK
Over time, insulin production declines as well, so many people with type 2 diabetes eventually need to take insulin. ... However, long-term insulin independence is difficult to maintain, and eventually most recipients needed to start taking insulin ... Diabetes develops when the pancreas does not make enough insulin, the body's cells do not use insulin effectively, or both. As ... Type 2 diabetes usually begins with a condition called insulin resistance, in which the body has trouble using insulin ...
  https://www.niddk.nih.gov/health-information/diabetes/overview/insulin-medicines-treatments/pancreatic-islet-transplantation
*  Insulin
... testing for insulin level is most frequently ordered following a low glucose and/or when someone has acute or chronic ... The test for insulin measures insulin from both sources while the C-peptide test reflects insulin produced by the pancreas. ... al (2001). Elecsys Insulin Assay: Free Insulin Determination and the Absence of Cross-Reactivity with Insulin Lispro. Clinical ... Insulin resistance. High. Normal or somewhat elevated. Not enough insulin produced by the beta cells (as seen in diabetes, ...
  https://labtestsonline.org/tests/insulin
*  Insulin detemir - Wikipedia
Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin ... Insulin detemir is a long-acting human insulin analogue for maintaining the basal level of insulin. Novo Nordisk markets it ... Treat-to-Target Trial Comparing Insulin Detemir With NPH Insulin as Add-On Therapy to Oral Glucose-Lowering Drugs in Insulin- ... 16%, P = 0.008). Compared with NPH insulin, the risk for all hypoglycemia with insulin detemir was reduced by 47% (P < 0.001) ...
  https://en.wikipedia.org/wiki/Insulin_detemir
*  insulin | Infoplease
Insufficiency of insulin in the body results in diabetes . Insulin was one of the first products to be manufactured using ...
  https://www.infoplease.com/encyclopedia/medicine/anatomy-and-physiology/anatomy-and-physiology/insulin
*  Definition: Insulin Injections
Although researchers are testing other ways to give insulin, it's only available now in a form that must be injected just under ... Insulin Injections. Insulin is a hormone that lowers the level of glucose (a type of sugar) in the blood by helping glucose ... There are many types of injectable insulin, both short- and long-acting. Most people with diabetes take insulin injections ... Although researchers are testing other ways to give insulin, it's only available now in a form that must be injected just under ...
  http://kidshealth.org/NemoursXML/en/parents/insulin-injections.html
*  Word! Insulin Injections
Insulin Injections. Say: in-suh-lin in-jek-shuns. Insulin is an important hormone that keeps your body working. If a person ... There are many types of injectable insulin, both short- and long-acting. Most people with diabetes take insulin injections ... doesn't make enough of this substance, he or she may need to get insulin injections, or shots. ...
  http://kidshealth.org/en/kids/word-insulin-injections.html?view=ptr&WT.ac=k-ptr
*  Word! Insulin Resistance
... the body doesn't let insulin do its job as well and it's harder for glucose to get into the cells. This is called insulin ... Even though the pancreas is still making insulin, ... This is called insulin resistance. People who have insulin ... but the insulin can't work the way it should. Even though the pancreas is still making insulin, the body doesn't let insulin do ... Kids who are starting to get type 2 diabetes are still able to make insulin, ...
  http://kidshealth.org/CookChildrens/en/kids/word-insulin-resistance.html
*  Blood Test: Insulin
... or any other conditions related to abnormal insulin production. ... Blood Test: Insulin. Resources. Please Note: By clicking a link ...
  http://kidshealth.org/en/parents/test-insulin.html?view=rr&WT.ac=p-rr
*  Blood Test: Insulin
... or any other conditions related to abnormal insulin production. ... Insulin works like a key that opens the doors to cells and ... For good health, the body must be able to keep insulin and glucose levels in balance. With too little insulin, blood sugar ... causing the pancreas to overcompensate and produce more insulin. Insulin resistance is common among obese people who may go on ... or any other conditions related to abnormal insulin production. It's often used to diagnose and monitor insulin resistance, a ...
  http://kidshealth.org/PrimaryChildrens/en/parents/test-insulin.html
*  NovoRapid (insulin aspart)
... all contain the active ingredient insulin aspart. They are used to treat diabetes. ... The insulin works in the same way as natural insulin, by binding to insulin receptors on cells in the body. Insulin causes ... NovoRapid injections contain a type of insulin called insulin aspart. This is known as a fast-acting insulin. When it is ... Your insulin requirements may increase when you are ill, especially if you have an infection or fever. Your insulin dose may ...
  http://www.netdoctor.co.uk/medicines/diabetes/a8319/novorapid-insulin-aspart/
*  Insulin | LabCorp
Why does insulin have to be injected?. Insulin must be injected or given via an insulin pump. It cannot be given orally because ... Fasting Insulin Formal name:. Insulin, serum Related tests:. C-peptide, Glucose Tests Why Get Tested?. To help evaluate insulin ... The test for insulin measures insulin from both sources while the C-peptide test reflects insulin produced by the pancreas. ... al (2001). Elecsys Insulin Assay: Free Insulin Determination and the Absence of Cross-Reactivity with Insulin Lispro. Clinical ...
  https://www.labcorp.com/help/patient-test-info/insulin