Combinations of Nondiabetic Parental Genomes Elicit Impaired Glucose Tolerance in Mouse SMXA Recombinant Inbred Strains |...
... and 19 SMXA RI strains were obtained from The Institute for Laboratory Animal Research, Nagoya University School of Medicine ( ... RESEARCH DESIGN AND METHODS. Animals.. Male mice of parental (SM/J, A/J) strains, (SM/J × A/J)F1 mice, ... Recombinant inbred (RI) strains are derived by inbreeding different sets of F2 progeny from a cross between two inbred strains ... 2Institute for Laboratory Animal Research, Nagoya University School of Medicine, Nagoya, Japan. ...http://diabetes.diabetesjournals.org/content/52/1/180
Optimization of condition(s) towards establishment of primary islet cell cultures from WNIN/Ob mutant rat | Springer for...
... developed at the National Center for Laboratory Animal Sciences (NCLAS) facility of National Institute of Nutrition (NIN), is a ... Inbred Wistar rat strain established at NIN. WNIN/Ob. Wistar rats raised in the National Institute of Nutrition, with obesity ... facility of National Institute of Nutrition (NIN), is a new animal model to study the metabolic syndrome. These animals have 47 ... 1.National Centre for Laboratory Animal Science, National Institute of NutritionJamai OsmaniaHyderabadIndia ...https://rd.springer.com/article/10.1007/s10616-011-9409-y
Laboratory rat - Wikipedia
Institute for Laboratory Animal Research. 32 (3): 4-8. doi:10.1093/ilar.32.3.4. Retrieved 2014-03-08. Mark A. Suckow, Steven H ... Inbred strains are also available but are not as commonly used as inbred mice Much of the genome of Rattus norvegicus has been ... Krinke, George J. (June 15, 2000). "History, Strains and Models". The Laboratory Rat (Handbook of Experimental Animals). ... "Outbred rats - Sprague Dawley® Outbred Rat". Harlan Laboratories - Animal Research Laboratory - Contract Research Services. ...https://en.wikipedia.org/wiki/Laboratory_rat
Animal Experimentation in a Large Research Institute | ari.info | ari.info
... notably of inbred animals and of first generation hybrids between inbred strains. This innova-tion met with a good deal of ... There have been two other such revolutions in laboratory animal husbandry. The second was the provision and use of animals of ... Research at the Institute is by no means confined to the use of lower animals; perhaps no Institute makes greater use of human ... The animals in Research Institutes are of necessity kept at a population density which makes them an easy prey to epidemics. To ...http://www.animalresearch.info/de/medizinischer-fortschritt/artikel-und-vorlesungen/animal-experimentation-large-research-institute/
Booktopia - Genetic Variants and Strains of the Laboratory Mouse by Mary F. Lyon, 9780198548690. Buy this book online.
Buy a discounted Hardcover of Genetic Variants and Strains of the Laboratory Mouse online from Australia's leading online ... Booktopia has Genetic Variants and Strains of the Laboratory Mouse by Mary F. Lyon. ... research faculty, and industrial scientists across various fields.' Mitzi Nagarkatti, Virginia Polytechnic Institute and State ... Rules for nomenclature of inbred strains 15: Origins and characteristics of inbred strains of mice 16: The laboratory mouse and ...https://www.booktopia.com.au/genetic-variants-and-strains-of-the-laboratory-mouse-mary-f-lyon/prod9780198548690.html
RFA-ES-17-009: Population-Based Model Organism Research for G x E Exploration in Complex Disease Outcomes (R01 Clinical Trial...
Population-Based Model Organism Research for G x E Exploration in Complex Disease Outcomes (R01 Clinical Trial Not Allowed) RFA ... Until now, most laboratory mouse strains were inbred or outbred from a small group of founder animals. Thus, mapping complex ... Scientific/Research Contact(s). Kimberly A. McAllister, Ph.D.. National Institute of Environmental Health Sciences (NIEHS). ... for Review of the Vertebrate Animal Section. ... recombinant inbred strains of the Collaborative Cross (CC) and ...https://grants.nih.gov/grants/guide/rfa-files/RFA-ES-17-009.html
Experimental Animals. All procedures were carried out in accordance with the Institute for Laboratory Animal Research Guide for ... Second, each inbred strain represented almost an exclusively homozygous genotype such that variation between inbred strains ... for inbred strains was 0.13 ± 0.06. This estimate for heritability from a panel of inbred strains was based upon two ... Population 1 (n = 120) comprised 10 commonly used and phylogenetically diverse inbred strains (6 males and 6 females per strain ...http://physiolgenomics.physiology.org/content/45/14/606
Michael Festing - Wikipedia
... including International Index of Laboratory Animals and Inbred Strains in Biomedical Research. He was the winner in 1996 of the ... which funds and promotes research into the use of animal alternatives. He is also a council member of the Institute of ... the use of animals in medical experiments in the UK. Festing is the author of over 200 scientific papers on laboratory animal ... "GlaxoSmithKline laboratory animal welfare prize", Research Defence Society. ...https://en.wikipedia.org/wiki/Michael_Festing
Naked mole rats: Can they help us cure cancer?
Maine as a central training ground for research animals.* By the end of the 1940s, Little's Jackson Laboratory had more than ... The classic inbred strains, mobilized for the war on cancer many decades ago, may offer the certainty of data and the most ... She's only trying to do what thousands of her research colleagues do every week of the year. She's trying to make an animal ... Mark Mattson, a senior scientist at the National Institute on Aging, calls the standard lab rodents "couch potatoes" and argues ...http://www.slate.com/articles/health_and_science/the_mouse_trap/2011/11/naked_mole_rats_can_they_help_us_cure_cancer_.single.html
Taconic Insights | Taconic Biosciences
Taconic Biosciences has remained one of the world's leading providers of research models and services for over 60 years through ... Animal Research Sample Size Calculation (and Consequences). Proper sample size calculation is both a scientific and ethical ... Each category requires a distinct approach to maintaining genetic integrity: Inbred strains have a... ... During the third week of January The National Institute on Drug Abuse (NIDA) and National Institute on Alcohol Abuse and ...https://www.taconic.com/cgi-bin/mt/mt-search.cgi?search=&IncludeBlogs=7&archive_type=Index&template_id=1269&limit=10&page=1
Cotton Rats as Animal Model for Infectious Diseases | College of Veterinary Medicine
Commercial suppliers for this inbred strain are in the USA Harlan Inc., Ace Animals and Virion Systems, and in Europe Charles ... Diversifying animal models: the use of hispid cotton rats (Sigmodon hispidus in infectious diseases. Laboratory Animals 36: 357 ... Inbred cotton rats. Cotton rats were inbred by the Veterinary Branch of the National Institutes of Health. ... Handling the cotton rat for research. Lab Animal 1: 31-36.. Niewiesk, S., F. Völp and V. ter Meulen (1997).. A maintenance and ...https://vet.osu.edu/cotton-rats-animal-model-infectious-diseases
The Animal House at IMBB is an independent facility consisting of: the main SPF unit which houses 3000-4000 mice for the ... The Animal House breeds, maintains and supplies inbred, random-bred, hybrid strain/s of mice, for the experimental use of ... A small area has been reserved as a virology laboratory to diagnose viral diseases in laboratory animals. The restricted to ... The experienced and helpful technical staff of the Animal House assists the research workers in their animal experiments, and ...http://www.imbb.forth.gr/el/facilities-el/cells-animals-el/item/132-animal-house?tmpl=component&print=1
Mus musculus - Academic Kids
... research institutes seek voluntary accreditation which requires certain minimal standards of care for laboratory animals. This ... Laboratory mice are often white, and some are albinos. Many (but not all) laboratory strains are inbred, so as to make them ... The US Animal Welfare Act covers most mammals but specifically excludes laboratory mice and rats. Most academic ... Laboratory mice are strains of house mice that form important model organisms in biology and medicine; they are the most ...http://effort.academickids.com/encyclopedia/index.php/Mus_musculus
Coisogenic strain - Wikipedia
National Research Council; Institute for Laboratory Animal Research; Commission on Life Sciences; Committee on Rodents. "3. ... heterozygous animals should be used to breed with the original inbred strain. Full-sib mating are used to maintain coisogenic ... Coisogenic strains may also occur through a spontaneous mutation that occurs in an inbred strain. To create a coisogenic strain ... Coisogenic strains are one type of inbred strain that differs by a mutation at a single locus and all of the other loci are ...https://en.wikipedia.org/wiki/Coisogenic_strain
Protocols and Video Articles Authored by Atsushi Yoshiki (Translated to Hindi)
Unique Inbred Strain MSM/Ms Established from the Japanese Wild Mouse Experimental Animals / Japanese Association for Laboratory ... National Research Council, Institute of Laboratory Animal Resources. 2006 , Pubmed ID: 16547366 Now that sequencing of the ... Japanese Association for Laboratory Animal Science. *Experimental Animals / Japanese Association for Laboratory Animal Science ... Inbred laboratory mouse strains are genetically uniform due to extensive inbreeding, and they have greatly contributed to the ...https://www.jove.com/author/Atsushi_Yoshiki?language=Hindi
A Critical Role for Induced IgM in the Protection against West Nile Virus Infection | JEM
All mice used in these experiments were derived from or backcrossed onto the inbred C57BL/6J strain. Mice that lack the ability ... The Center for Blood Research, Harvard Medical School, Boston, MA) and J. Chen (Massachusetts Institute of Technology, ... 20 animals were included in the study. 8 survived and 12 died after infection. Five of the animals that died had identical ... Previous studies in our laboratory with B cell-deficient μMT C57BL/6J mice indicated that B cells and antibody had a critical ...http://jem.rupress.org/content/198/12/1853
MGI-Guidelines for Nomenclature of Mouse and Rat Strains
Laboratory codes are assigned by the Institute of Laboratory Animal Research (ILAR) (http://dels.nas.edu/global/ilar/lab-codes ... Traditionally, recombinant inbred (RI) strains are formed by crossing animals of two inbred strains, followed by 20 or more ... 4. Strains Made from Multiple Inbred Strains. 4.1 Recombinant Inbred Strains. 4.2 Collaborative Cross Strains. 4.3 Mixed Inbred ... 4.3 Mixed Inbred Strains. Incipient inbred stocks or inbred strains that are derived from up to three parental strains (one of ...http://www.informatics.jax.org/mgihome/nomen/strains.shtml
BALB/c - Wikipedia
... and are among the most widely used inbred strains used in animal experimentation. The founding animals of the strain were ... Animal model Animal testing on rodents C57BL/6 Jackson Laboratory's mouse strains Taconic Bioscience's BALB/c model "BALB/c". ... BALB/c mice are useful for research into both cancer and immunology. According to Michael Festing's Inbred Strains of Mice, ... Snell provided some animals from this stock to the National Institutes of Health (NIH) to maintain. In 1961 D. W. Bailey used ...https://en.wikipedia.org/wiki/BALB/c
MGI-Rules and Guidelines for Nomenclature of Mouse and Rat Strains
Laboratory codes are assigned by the Institute of Laboratory Animal Research (ILAR) (http://dels.nas.edu/ilar_n/ilarhome/search ... Traditionally, recombinant inbred (RI) strains are formed by crossing animals of two inbred strains, followed by 20 or more ... 4 Strains Made from Multiple Inbred Strains. 4.1 Recombinant Inbred Strains. 4.2 Mixed Inbred Strains. 4.3 Recombinant Congenic ... 5.1 Coisogenic Strains. 5.2 Congenic Strains. 5.3 Consomic Strains. 5.4 Segregating Inbred Strains. 5.5 Conplastic Strains. 6 ...http://www.informatics.jax.org/mgihome/nomen/2006_strains.shtml
Diet-induced obesity model - Wikipedia
Balcombe, J. P. (2006-07-01). "Laboratory environments and rodents' behavioural needs: a review". Laboratory Animals. 40 (3): ... West, D. B.; Boozer, C. N.; Moody, D. L.; Atkinson, R. L. (1992-06-01). "Dietary obesity in nine inbred mouse strains". The ... National Human Genome Research Institute. Retrieved November 13, 2016. Upadhyay, Vaibhav; Poroyko, Valeriy; Kim, Tae-jin; ... The diet-induced obesity model (DIO model) is an animal model used to study obesity using animals that have obesity caused by ...https://en.wikipedia.org/wiki/Diet-induced_obesity_model
2012 Landes Bioscience. Do not distribute. - PDF
2011 Landes Bioscience Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice Vladimir N. ... Inbred 129/Sv female mice, originally obtained from Jackson Laboratory by the International Agency for Research on Cancer (IARC ... Petrov Research Institute of Oncology. 44 The animals were kept 5 7 in polypropylene cages (30 x 21 x 10 cm) under a standard ... Use of inbred strains of mice will allow one to compare results and to choose the most beneficial schedules of rapamycin ...http://docplayer.net/246628-2012-landes-bioscience-do-not-distribute.html
Cheetah countdown: does inbreeding - or zoo life - hinder this feline's fecundity? - Free Online Library
... general Animal infertility Research Cheetahs Infertility in animals Zoo animals ... does inbreeding - or zoo life - hinder this feline's fecundity? (Cover Story) by 'Science News'; Science and technology, ... data showing that wild as well as zoobound cheetahs have no more genetic variability than highly inbred strains of laboratory ... part of the National Cancer Institute. He suggested thatt this genetic homogeneity also made this species unusually susceptible ...https://www.thefreelibrary.com/Cheetah+countdown%3A+does+inbreeding+-+or+zoo+life+-+hinder+this...-a014504047
CiNii 論文 - Genetic mapping of genes regulating the thymus size in back-cross rats between the...
Research Institute of Environmental Medicine, Nagoya University * * ODA Sen-ichi * Laboratory of Animal Management, School of ... Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains BERRETTINI W. H. ... Hemopoietic System : Monographs on Pathology of Laboratory Animals, 275-280, 1990 被引用文献1件 ... Genetic mapping of genes regulating the thymus size in back-cross rats between the laboratory BUF/Mna strain and the MITE ...http://ci.nii.ac.jp/naid/10008338683
Laboratory mouse - Wikipedia
PHS policy is administered by the Office of Laboratory Animal Welfare. Many academic research institutes seek accreditation ... "BALB/c". Inbred Strains of Mice. Jackson Laboratory. Retrieved 2007-04-16. "BALB/cByJ". Jax Mice Data Sheet. Jackson Laboratory ... "Office of Laboratory Animal Welfare: PHS Policy on Humane Care and Use of Laboratory Animals". Grants.nih.gov. Retrieved 2010- ... Laboratory rat Animal testing Animal testing on rodents Animal model Animal Identification Mouse models of colorectal and ...https://en.wikipedia.org/wiki/Laboratory_mouse
Lab mice: Are they limiting our understanding of human disease?
At the National Institute on Aging, as at every major research center, the animals are grouped in plastic cages the size of ... and other strains like it, have grown fatter and more fertile than any inbred strain. It's an all-purpose mouse sometimes used ... In her biosafety-level-3 laboratory at the University of Pittsburgh, Flynn has used the standard animal model of TB to work out ... the government needed a more streamlined research model-a lab animal, or a set of lab animals, that could be standardized and ...http://www.slate.com/articles/health_and_science/the_mouse_trap/2011/11/lab_mice_are_they_limiting_our_understanding_of_human_disease_.html?wpisrc=newsletter_tis