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*  Cementoblast - Wikipedia
... and whose biological function is cementogenesis, which is the formation of cementum (hard tissue that covers the tooth root). ... Noggin (protein) is a BMP inhibitor that correlates with BMP-2 to regulate gene expression and mineral nodule formation. BMP-2 ... The progenitor cells also found in the PDL region contribute to the mineralization of the tissue. Once in this situation, the ... these cells can then produce cementum if the tooth is injured (see hypercementosis). Cementum Cementogenesis Tooth development ...
  https://en.wikipedia.org/wiki/Cementoblast
*  Hot Papers | Page 2 | NIH Intramural Research Program
Inorganic pyrophosphate (PPi), a mineralization inhibitor, is a key regulator of cementum formation: tissue-nonspecific ... Although acellular cementum is essential for tooth attachment, factors directing its development and regeneration remain poorly ... Overlapping functions of bone sialoprotein and pyrophosphate regulators in directing cementogenesis. September 2017 ... We propose that BSP and PPi work in concert to direct mineralization in cementum and likely other mineralized tissues. ...
  https://irp.nih.gov/news-and-events/hot-papers?page=1
*  Current knowledge of tooth development: patterning and mineralization of the murine dentition - Catón - 2009 - Journal of...
Tooth hard tissue. The later stages of tooth development are characterized by the formation of the mineralized tissue: dentin, ... In contrast, in patients with a mutation in AXIN2 (axis inhibitor 2) severe tooth loss is observed in permanent molars, ... has been shown to have a role in the upregulation of osteopontin in cementogenesis via the MAPK pathway (Boabaid et al. 2004). ... Reducing tooth number. In the mouse, the number of tooth germs that form has been reduced by the death of tooth germs that ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1469-7580.2008.01014.x/full
*  Immunohistochemical Localization of Osteopontin - A Comparative Study on Periodontally Healthy and Diseased Tooth Root Surface
A Comparative Study on Periodontally Healthy and Diseased Tooth Root Surface, Julie Toby Thomas, Toby ... OPN also plays a protective role during tooth development by acting as an inhibitor/regulator of mineralization. ... They inhibited or delayed the formation of collagen, as well as expression of BSP and OPN along the root surfaces, which seem ... osteopontin are the two major non-collagenous proteins in cementum that appeared to have important roles in cementogenesis and ...
  http://periodontics-prosthodontics.imedpub.com/immunohistochemical-localization-of-osteopontin--a-comparative-study-on-periodontally-healthy-and-diseased-tooth-root-surface.php?aid=21109
*  Biology of periodontal regeneration
Osteoblasts are specialized stromal cells that are exclusively responsible for the formation, deposition and mineralization of ... Cementum attachment protein is a collagenous protein that is expressed in the matrix of tooth cementum. This protein binds with ... Fibroblast and macrophage chemotaxisExtracellular matrix synthesisSecretion of protease inhibitors. Insulin-like growth factor ... It promotes attachment of mesenchymal cells and may function in cementogenesis. This protein is capable of recruiting ...
  http://periobasics.com/biology-of-periodontal-regeneration.html
*  Methods and Systems for Mineralization of Demineralized Tissue - Patent application
... nucleators or inhibitors, growth modifiers, anchoring molecules, or as scaffolds for mineral deposition during tooth ... 3B shows that, in one embodiment, PAA may be used stimulate apatite crystal formation. In FIG. 3B, crystal formation is ... stimulating dentinogenesis and cementogenesis (Sarkar, N. K. et al., J. Endod., 2005, 31:97-100; Ford, T. R. et al., J. Am. ... The cementum is a thin, fairly hard bone tissue covering the root of the tooth. [0004]Dental caries, also known as tooth decay ...
  http://www.patentsencyclopedia.com/app/20100086618
*  Fulltext | Tissue Engineering of Craniofacial Tissues - A Review | Journal of Regenerative Medicine and Tissue Engineering
The role of mesenchymal stem cells in the formation of all craniofacial and dental structures has been well ... C. Du, F. Z. Cui, X. D. Zhu, K. de Groot: Formation of calcium phosphate/collagen composites through mineralization of collagen ... SCAPs exhibit a higher proliferative rate and appear more effective than PDLSC for tooth formation. Importantly, SCAP are ... Induction of cementogenesis by recombinant human osteogenic protein-1 (hop-1/bmp-7) in the baboon (Papio ursinus). Arch Oral ...
  http://www.hoajonline.com/jrmte/2050-1218/2/6