*  Renal Fellow Network: How to best design RCTs for new transplant immunosuppressives
With the advent of drugs such as calcineurin inhibitors, induction agents such as thymoglobulin, azathioprine and later MMF, ... immunosuppressive therapy (38) infectious disease (24) interstitial nephritis (20) lupus nephritis (17) membranous nephropathy ...
  http://renalfellow.blogspot.com/2009/10/how-to-best-design-rcts-for-new.html
*  Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML) - Tabular View -...
Patients on immunosuppressive therapy post HSCT, or with clinically significant graft-versus-host disease are excluded from ... For patients whose most recent anti-tumor treatment regimen consisted of a multi-agent cocktail, the patient must have a wash- ... Patients for Part 2 may be receiving systemic immunosuppressive treatment for management of GVHD at the time of screening and ... out period of at least 4 half-lives of the agent with the longest half-life. ...
  https://clinicaltrials.gov/ct2/show/record/NCT01349049
*  Immunosuppressive compounds - Vertex Pharmaceuticals, Inc.
This invention relates to a novel class of immunosuppressive compounds having an affinity for the FK-506 binding protein (FKBP ... Once bound to this protein, the immunosuppressive compounds inhibit the ... has been demonstrated to be a potent immunosuppressive agent. Tanaka, H. et al., J. Am. Chem. Soc. 109:5031-5033 (1987). FK-506 ... The immunosuppressive compounds of this invention have an affinity for the FK-506 binding protein which is located in the ...
  http://www.freepatentsonline.com/5192773.html
*  "Immunosuppressive strategies to avoid complications: The Achilles' hee" by Gregory Smallwood
RECENT FINDINGS: Immunosuppressive protocols that avoid or minimize the use of calcineurin inhibitors hold the promise of ... SUMMARY: It is important to appreciate that the long-term benefits of new immunosuppressive strategies have yet to stand the ... RECENT FINDINGS: Immunosuppressive protocols that avoid or minimize the use of calcineurin inhibitors hold the promise of ... SUMMARY: It is important to appreciate that the long-term benefits of new immunosuppressive strategies have yet to stand the ...
  https://digitalcommons.pcom.edu/scholarly_papers/1191/
*  JoVE Author Search: Sfriso P
Immunosuppressive Agents, Joint, Morbidity, Patients, Skin, Syndrome, Therapeutic, Treatment, Uveitis ... Immunosuppressive Agents, Joint, Morbidity, Patients, Skin, Syndrome, Therapeutic, Treatment, Uveitis. ...
  http://labindex.jove.com/author/Sfriso-P
*  Immunosuppressive Medications for Participants in ITN005CT (NCT00014911) - Full Text View - ClinicalTrials.gov
Anti-Bacterial Agents. Anti-Infective Agents. Antibiotics, Antineoplastic. Antineoplastic Agents. Antifungal Agents. ... Immunosuppressive Agents. Mycophenolic Acid. Immunologic Factors. Physiological Effects of Drugs. Calcineurin Inhibitors. ... Immunosuppressive regimen consisting of a single agent or some combination from among the following: tacrolimus, sirolimus, ... Immunosuppressive Medications for Participants in ITN005CT (NCT00014911). Expanded access is no longer available for this ...
  https://clinicaltrials.gov/ct2/show/NCT01309022?term=NIAID&recr=Open&no_unk=Y&sntx=
*  Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA) - Full Text View -...
Immunosuppressive Agents. Immunologic Factors. Physiological Effects of Drugs. Calcineurin Inhibitors. Enzyme Inhibitors. ... Antineoplastic Agents. Antibiotics, Antitubercular. Antitubercular Agents. Anti-Bacterial Agents. Anti-Infective Agents. ...
  https://clinicaltrials.gov/ct2/show/NCT00290069
*  Immunosuppressive Agents | SpringerLink
Induction agents, or intense immunosuppression given at the time of transplant to prevent acute rejection,... ... Hardinger K.L., Agha I.A., Brennan D.C. (2016) Immunosuppressive Agents. In: Ljungman P., Snydman D., Boeckh M. (eds) ... Induction agents, or intense immunosuppression given at the time of transplant to prevent acute rejection, include polyclonal ... Rescue agents, or medications used to treat rejection, include corticosteroids, antithymocyte globulins, and alemtuzumab. When ...
  https://link.springer.com/chapter/10.1007/978-3-319-28797-3_3
*  Immunosuppressive agents for treating IgA nephropathy | Cochrane
Immunosuppressive agents for treating IgA nephropathy. IgA nephropathy is a common kidney disease that often leads to decreased ... Immunosuppressive agents for treating IgA nephropathy. Cochrane Database of Systematic Reviews 2015, Issue 8. Art. No.: ... Evidence for treatment effects of immunosuppressive agents on mortality, infection, and cancer is generally sparse or low- ... RCTs of treatment for IgAN in adults and children and that compared immunosuppressive agents with placebo, no treatment, or ...
  http://www.cochrane.org/CD003965/RENAL_immunosuppressive-agents-treating-iga-nephropathy
*  Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents - Full...
Antifungal Agents. Anti-Infective Agents. Dermatologic Agents. Antirheumatic Agents. Antibiotics, Antineoplastic. ... Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents. The ... Immunosuppressive Agents. Mycophenolic Acid. Immunologic Factors. Physiological Effects of Drugs. Calcineurin Inhibitors. ... Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents. ...
  https://clinicaltrials.gov/ct2/show/NCT01678937
*  Risk of serious infections associated with use of immunosuppressive agents in pregnant women with autoimmune inflammatory...
Increased risk of infections is one of the most important concerns associated with the use of immunosuppressive agents as they ... Increased risk of infections is one of the most important concerns associated with immunosuppressive agents as they ... Results 71 out of 4961 pregnant women (0.2%) treated with immunosuppressive agents experienced serious infections. The crude ... Risk of serious infections associated with use of immunosuppressive agents in pregnant women with autoimmune inflammatory ...
  http://www.bmj.com/content/356/bmj.j895
*  US5349060A - Rapamycin 31-ester with N,N-dimethylglycine derivatives useful as immunosuppressive agents - Google...
... which by virtue of its immunosuppressive activity is useful in treating transplantation rejection, host versus graft disease, ... flavoring agents, suspending agents, thickening agents, colors, viscosity regulators, stabilizers or osmo-regulators. Suitable ... Rapamycin arylcarbonyl and alkoxycarbonyl carbamates as immunosuppressive and antifungal agents Patent Citations (23). * Cited ... Rapamycin 31-ester with N,N-dimethylglycine derivatives useful as immunosuppressive agents Download PDF Info. Publication ...
  https://patents.google.com/patent/US5349060A/en
*  Graft Versus Host Disease Medication: Immunosuppressive agents, Immunomodulating agents, Photoactive agents, Antineoplastic...
Ig-containing immunosuppressive agent. Immunosuppressive action generally similar to that of other antilymphocyte preparations ... Therapy includes immunosuppressive agents, antimetabolite and/or chemotherapeutic agents, antibodies and/or immunoglobulins, ... Immunosuppressive agents. Class Summary. Corticosteroids are the mainstay for treatment of GVHD. Corticosteroids cause profound ... The 2-morpholinoethyl ester of mycophenolic acid (MPA), an immunosuppressive agent. Inhibits purine synthesis and proliferation ...
  https://emedicine.medscape.com/article/429037-medication
*  Pediatric Systemic Lupus Erythematosus Medication: Antimalarial agents, Corticosteroids, Immunosuppressive agents, Calcium and...
Immunosuppressive agents. Class Summary. Evaluate children with signs of active nephritis to determine the WHO classification ... These agents elicit anti-inflammatory and immunosuppressive properties, cause profound and varied metabolic effects, and modify ... Antimalarial agents. Class Summary. Rash and other minor symptoms, including musculoskeletal symptoms, can be treated with ... Select a specific agent based on patient response to medication, history of previous drug allergy or reaction, and ease of use ...
  https://emedicine.medscape.com/article/1008066-medication
*  Mitosan - Antineoplastic Agents, Immunosuppressive Agents, Alkylating Agents, ATC:L01AB01
Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the ... Busulfan is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents ...
  http://pharmacycode.com/Mitosan.html
*  Aims Mizoribine can be an oral immunosuppressive agent approved in several - Small Molecule Inhibitors of Protein Arginine...
Aims Mizoribine can be an oral immunosuppressive agent approved in several. by Ross Marshall ... Aims Mizoribine can be an oral immunosuppressive agent approved in several countries for prevention of rejection in renal ... of adverse occasions at current scientific doses possibly makes high-dose mizoribine a stunning choice immunosuppressive agent ... As opposed to various other Daptomycin immunosuppressive realtors (e.g. azathioprine), mizoribine provides been proven in ...
  http://welbourneprimary.com/aims-mizoribine-can-be-an-oral-immunosuppressive-agent-approved-in-several/
*  The efficacy and safety of immunosuppressive agents in the treatment of necrotizing scleritis - A multi-center retrospective...
Hyun Sun Jeon, Mee Kum Kim, Joon-Young Hyon; The efficacy and safety of immunosuppressive agents in the treatment of ... The efficacy and safety of immunosuppressive agents in the treatment of necrotizing scleritis - A multi-center retrospective ... The efficacy and safety of immunosuppressive agents in the treatment of necrotizing scleritis - A multi-center retrospective ... case series study to investigate the efficacy and safety of immunosuppressive agents (ISA) in the treatment of necrotizing ...
  http://iovs.arvojournals.org/article.aspx?articleid=2335865
*  北京大学医学部机构知识库(IR@PKUHSC): N-Arylated-Lactam-Type Iminosugars as New Immunosuppressive Agents: Discovery, Optimization, and...
Wu, Xiaowei,et al."N-Arylated-Lactam-Type Iminosugars as New Immunosuppressive Agents: Discovery, Optimization, and Biological ... N-Arylated-Lactam-Type Iminosugars as New Immunosuppressive Agents: Discovery, Optimization, and Biological Evaluation. ... N-Arylated-Lactam-Type Iminosugars as New Immunosuppressive Agents: Discovery, Optimization, and Biological Evaluation[J]. ... N-Arylated-Lactam-Type Iminosugars as New Immunosuppressive Agents: Discovery, Optimization, and Biological Evaluation. ...
  http://ir.bjmu.edu.cn/handle/400002259/56519
*  IME Pharmacology (Chapter 30-Immunizing Agents and Immunosuppressives) Flashcards - Cram.com
Chapter 30-Immunizing Agents and Immunosuppressives) at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com ... Ime Pharmacology (Chapter 30-Immunizing Agents And Immunosuppressives). by jonndell9, Sep. 2007 ... ime-pharmacology-chapter-30-immunizing-agents-and-immunosuppressives-500632","isGuest":true,"ga_id":"UA-272909-1","facebook":{" ... Chapter 30-Immunizing Agents and Immunosuppressives)","payreferer_url":"\/flashcards\/copy\/ ...
  http://www.cram.com/flashcards/ime-pharmacology-chapter-30-immunizing-agents-and-immunosuppressives-500632
*  Scleroderma | University of Maryland Medical Center
Immunosuppressive Agents. D-penicillamine is proving to be an effective agent for softening skin and reducing thickness. ( ... Other agents including erythromycin, azithromycin and domperidone may also be helpful.. Agents for Constipation. Prokinetics. ... These agents show some promise, but additional study is needed to define their use:. *Bosentan is currently under study in the ... Many non-prescription agents are available for the relief of heartburn.. Proton-pump or acid-pump inhibitors are probably the ...
  http://www.umm.edu/health/medical/reports/articles/scleroderma
*  KRP-203, a Novel Synthetic Immunosuppressant, Prolongs Graft Survival and Attenuates Chronic Rejection in Rat Skin and Heart...
Experimental Animals and Immunosuppressive Agents. Inbred male DA (MHC haplotype: RT1a) rats were obtained from Japan SLC Inc ( ... The numbers in parentheses indicate the dose (mg · kg−1 · d−1) of immunosuppressive agents. LN indicates lymph node. *P,0.05 ... The numbers in parentheses indicate the dose (mg · kg−1 · d−1) of immunosuppressive agents. *P,0.05 vs control group. ... The numbers in parentheses indicate the dose (mg · kg−1 · d−1) of immunosuppressive agents. *P,0.05 vs control group. ...
  http://circ.ahajournals.org/content/111/2/222
*  Kidney Transplantation: Transplant Immunology and Use of Immunosuppression - ONA
As a class mTOR inhibitors tend to be less immunosuppressive than the CNIs but stronger than other anti-proliferative agents. ... Which antiproliferative agent should I use?. *. The most used antiproliferative agent is MMF, which has been shown to decrease ... Target trough levels vary depending on other agents it is being used with and will be discussed in the immunosuppressive ... Induction agents:. Used to decrease the risk of rejection early post transplant when the risk is the highest. These agents can ...
  http://www.oncologynurseadvisor.com/nephrology-hypertension/kidney-transplantation-transplant-immunology-and-use-of-immunosuppression/article/616141/
*  Publications | AIDS Clinical Trials Group
Immunosuppressive Agents. Markowitz M, Vaida F, C Hare B, et al. "The virologic and immunologic effects of cyclosporine as an ... Anti-HIV Agents. Markowitz M, Vaida F, C Hare B, et al. "The virologic and immunologic effects of cyclosporine as an adjunct to ...
  https://actgnetwork.org/pubmed_publications?s=keyword&o=asc&f%5Bauthor%5D=136
*  CellCept (Mycophenolate Mofetil): Side Effects, Interactions, Warning, Dosage & Uses
Combination With Other Immunosuppressive Agents. CellCept has been administered in combination with the following agents in ... The efficacy and safety of the use of CellCept in combination with other immunosuppressive agents have not been determined. ... Mycophenolate mofetil was used alone or in combination with other immunosuppressive agents in these studies. Mycophenolate ... CellCept (mycophenolate mofetil) is the 2-morpholinoethyl ester of mycophenolic acid (MPA), an immunosuppressive agent; inosine ...
  https://www.rxlist.com/cellcept-drug.htm
*  Complete Guide to Prescription & Nonprescription Drugs 2011 - H. Winter Griffith - Google Books
The revised and updated 2011 edition of the most accessible, comprehensive and affordable guide to prescription and nonprescription drugs. The classic guide to all major prescription and nonprescription drugs, featuring revised, up-to date FDA information and an A-Z list of medical conditions and their commonly used drugs for easy reference. It includes coverage of dosage and length of time before the drug takes effect, side effects, special precautions, interactions with other food and drugs, standards for use by different age groups, and much more. It also features a generic and brand name directory, a comprehensive glossary, and complete index by generic, brand, and class name.
  https://books.google.com/books/about/Complete_Guide_to_Prescription_and_Nonpr.html?id=6LdbptaO8zQC&hl=en