*  Daniel Goldstein, MBBS > Immunobiology | Yale School of...
We recently discovered that haptoglobin stimulates innate immunity to induce inflammation after organ transplantation (JCI, ... I am also interested in how aging impacts immunity, initially to determine if older transplant recipients exhibit altered ... As a transplant physician, I have investigated the mechanisms and consequences of innate immune activation after organ ... The activators of the innate immune system after transplantation have remained elusive. ...
  http://medicine.yale.edu/immuno/programs/daniel_goldstein.profile
*  Yersinia V-Antigen Exploits Toll-like Receptor 2 and CD14 for Interleukin 10-mediated Immunosuppression | JEM
In this study we focused on the signaling of V antigen-induced innate immunity responses. For the first time we demonstrate ... Innate immunity: impact on the adaptive immune response. Curr. Opin. Immunol. 9:4-9. ... The strategy of yersiniae to exploit an innate immunity effector, i.e., host macrophage-derived IL-10, might therefore be ... Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:675-680. ...
  http://jem.rupress.org/content/196/8/1017
*  The Scripps Research Institute - News and Views
A Systems Approach to Innate Immunity. Innate immunity is essential for survival in a world filled with microbial pathogens. ... "There are lots of questions we would like to ask about gene expression and protein expression in innate immunity," says TSRI ... The grant investigators aim to identify and study the key players of innate immunity on both sides of the battle. Investigators ... The group's task is to create an "encyclopedia" of innate immunity a comprehensive and detailed picture of this ancient, ...
  http://www.scripps.edu/newsandviews/e_20030113/grant.html
*  Lung Cancer Cells Activate Inflammation to Induce Metastasis - News from UC San Diego Medical Center
... explain how advanced cancer cells usurp components of the host innate immune system to generate an inflammatory ... However, the normal function of TLR2 and TNFa is in host defense-innate immunity to microbial infections. According to Karin, ... explain how advanced cancer cells usurp components of the host innate immune system to generate an inflammatory ...
  https://health.ucsd.edu/news/2009/Pages/1-5-Karin-Nature.aspx
*  Signatures of selection acting on the innate immunity gene Toll-like receptor 2 (TLR2) during the evolutionary history of...
Tschirren, Barbara; Raberg, Lars; Westerdahl, Helena (2011). Signatures of selection acting on the innate immunity gene Toll- ... Signatures of selection acting on the innate immunity gene Toll-like receptor 2 (TLR2) during the evolutionary history of ... To obtain a comprehensive understanding of evolutionary processes in host-parasite systems, both innate and acquired immunity ... To obtain a comprehensive understanding of evolutionary processes in host-parasite systems, both innate and acquired immunity ...
  http://www.zora.uzh.ch/id/eprint/73244/
*  Immunity to parasitic infections by Tracey Lamb - The Rockridge E-books
8 Adaptive immunity The adaptive immune response differs from the innate immune response because it has specificity and the ... 1 Functions of the innate and adaptive arms of the immune system. Innate Immune Cells Adaptive Immune Cells Immune recognition ... Immunity to parasitic infections by Tracey Lamb. Posted on March 1, 2017. by admin ... 1). The innate arm of the immune system recognises pathogens non-specifically and generates immediate generic mechanisms of ...
  http://rockridgebrothers.com/lib/immunity-to-parasitic-infections
*  Frontiers | Specific Pathogen Recognition by Multiple Innate Immune Sensors in an Invertebrate | Immunology
These findings highlight the diversity and complexity of a highly specific innate immune sensing system. It paves the way for ... This implies a mediation by different soluble and/or membrane-anchored proteins related to innate immune receptors called PRRs ... wide range of host-pathogen systems to provide new insights into the specificity and diversity of immune recognition by innate ... This implies a mediation by different soluble and/or membrane-anchored proteins related to innate immune receptors called PRRs ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.01249/full
*  Regulation of innate immune responses by autophagy-related proteins | JCB
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity. 27:135-144. doi:10.1016/j.immuni. ... Although innate immunity is essential for host defense, aberrant activation of innate immune responses results in the ... Autophagy in innate and adaptive immunity. Trends Immunol. 26:523-528. doi:10.1016/j.it.2005.08.003. ... Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 307:731-734. doi:10.1126/science. ...
  http://jcb.rupress.org/content/189/6/925
*  IL-1β is an innate immune sensor of microbial proteolysis | Science Immunology
Research ArticleINNATE IMMUNITY. IL-1β is an innate immune sensor of microbial proteolysis ... IL-1β is an innate immune sensor of microbial proteolysis. By Christopher N. LaRock, Jordan Todd, Doris L. LaRock, Joshua Olson ... IL-1β is an innate immune sensor of microbial proteolysis. By Christopher N. LaRock, Jordan Todd, Doris L. LaRock, Joshua Olson ... IL-1β is an innate immune sensor of microbial proteolysis Message Subject. (Your Name) has forwarded a page to you from Science ...
  http://immunology.sciencemag.org/content/1/2/eaah3539.full
*  Min-Jong Kang, MD, PhD, MPH > Kang Lab | Pulmonary, Critical Care & Sleep Medicine | Yale School of...
These studies led me to question the effect of CS on innate immunity on the interaction between the host and microorganisms and ... These studies revealed important insight into the interaction between CS and the innate immunity resulting in a publication in ... In that study, we identified that CS smoke selectively augments respiratory antiviral innate immune responses via a MAVS-RLHs ...
  http://medicine.yale.edu/lab/kang/members/min-jong_kang.profile?source=news
*  NIH Guide: INNATE IMMUNITY
... innate immunity and acquired immunity. The innate immune system provides broad, but relatively nonspecific host defenses that ... RESEARCH OBJECTIVES Background This PA will support studies of the mechanisms of innate or "natural" immunity. The innate ... This PA, "INNATE IMMUNITY", is related to the priority areas of Immunization and Infectious Diseases and Diabetes and Chronic ... The purpose of the PA is to support basic and preclinical studies of the mechanisms of innate immunity in order to: a) develop ...
  https://grants.nih.gov/grants/guide/pa-files/PA-97-079.html
*  Innate Immunity - QIAGEN
Solutions optimized for innate immunity studies include PCR array, miRNA, siRNA, mutation analysis, pathway reporter, chromatin ... QIAGEN provides a broad range of assay technologies for innate immunity research that enables analysis of gene expression and ... initiate innate immunity, the inborn host response to common pathogens such as viruses, bacteria, and fungi. These receptors ... initiate innate immunity, the inborn host response to common pathogens such as viruses, bacteria, and fungi. These receptors ...
  https://www.qiagen.com/sg/shop/genes-and-pathways/complete-biology-list/innate-immunity/
*  Postdoctoral Position in Innate Immunity
... jonf at duke.edu jonf at duke.edu Tue Jul 8 09:49:41 EST 2003 *Previous message: Will ... the molecular biological and genetic approaches currently used in the laboratory to elucidate mechanisms of innate immunity in ... and Critical Care Medicine at Duke University invites applications for a postdoctoral position to investigate innate immunity ...
  http://www.bio.net/bionet/mm/immuno/2003-July/017485.html
*  Innate Immunity and Inflammation | JEM
Contextual control of skin immunity and inflammation by Corynebacterium Vanessa K. Ridaura, Nicolas Bouladoux, Jan Claesen, Y. ... Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity Sabine Hoves, Chia-Huey Ooi, Carsten Wolter ... Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity Curtis J. Perry, Andrés R. Muñoz- ...
  http://jem.rupress.org/collection/innate-immunity-and-inflammation
*  Glycomics and innate immunity in human disease
... The Clinical Sciences Research Institute is hosting a seminar entitled ' ... Glycomics and innate immunity in human disease' from 12:30pm to 1:30pm on Thursday 21 January 2010 in the Large Seminar Room, ...
  https://warwick.ac.uk/insite/events/events/csri_daniel_mitchell/
*  Journal of Innate Immunity - Home - Karger Publishers
The Journal of Innate Immunity is a bimonthly journal covering all aspects of innate immunity, including: Evolution of the ... Journal of Innate Immunity. Journal Abbreviation: J Innate Immun. ISSN: 1662-811X (Print). e-ISSN: 1662-8128 (Online). DOI: ... Journal of Innate Immunity. Editor(s): Herwald H. (Lund) Egesten A. (Lund) Editorial Board ... Cellular Innate Immunity: An Old Game with New Players * Cells of Innate and Adaptive Immunity: A Matter of Class? ...
  https://content.karger.com/Journal/Home/234234
*  Research Profile - Hormones, microbiome and innate immunity - CIHR
Interactions between sex hormones, microbiome and innate immunity in the female reproductive tract: impact on mucosal immune ...
  http://www.cihr-irsc.gc.ca/e/49035.html
*  BioLegend Innate Immunity Category
Some of the major components of innate immunity include: the complement cascade, phagocytosis, Toll-like receptors, and ... Phagocytosis can lead to antigen presentation, which bridges innate and adaptive immunity. BioLegend develops and manufactures ... Innate immunity is the first line of defense against invading pathogens. This defense system can be found in plants, ...
  http://www.biolegend.com/category_innate_immunity_rat
*  Viruses | Free Full-Text | Innate Immunity Evasion by Dengue Virus
In this review, we will evaluate the contribution of innate immunity evasion by DENV to the pathogenesis and host tropism of ... they must evade or inhibit important elements of the innate immune system, namely the type I interferon (IFN) response, which ... negatively influences the subsequent development of antigen-specific adaptive immunity against those viruses. Dengue virus ( ... In this review, we will evaluate the contribution of innate immunity evasion by DENV to the pathogenesis and host tropism of ...
  http://www.mdpi.com/1999-4915/4/3/397
*  Tag: innate immunity | Highlight HEALTH
... for their discovery of receptor proteins that can recognize bacteria and other microorganisms and activate innate immunity, and ... for his discovery of dendritic cells of the immune system and their unique capacity to activate and regulate adaptive immunity ...
  http://www.highlighthealth.com/tag/innate-immunity/
*  Innate Immunity Tutorial | Sophia Learning
This lesson will describe innate immunity as the body's second line of defense against pathogens. ,/p, ... We explain Innate Immunity with video tutorials and quizzes, using our Many Ways(TM) approach from multiple teachers.,p, ... Innate Immunity Also known as non-specific immunity, innate immunity consists of general physiologic responses (fever, ... This lesson will describe innate immunity as the body's second line of defense against pathogens. ...
  https://www.sophia.org/tutorials/innate-immunity--3
*  Interaction between biomaterials and innate immunity with clinical implications
... Huang, Shan Linnaeus University, Faculty of ... on top of which the innate immune system is triggered, with potentially detrimental consequences. The work presented in this ...
  http://www.diva-portal.org/smash/record.jsf?pid=diva2:873627
*  Ipr1 Gene that influences Innate Immunity to Tuberculosis
... By Harvard School of Public Health. Apr 14, 2005, 16:21. ... However, individual host resistance genes such as Ipr1, involved in innate immunity for tuberculosis, have been difficult to ... Of interest, the Ipr1 gene also controls innate immunity to another intracellular pathogen Listeria monocytogenes, a parasitic ... equivalent within a highly conserved genetic region suggests that the human equivalent may also be involved in innate immunity ...
  http://www.rxpgnews.com/research/infectiousdiseases/tuberculosis/printer_1118.shtml
*  Functions of noncoding RNA in Innate Immunity | Frontiers Research Topic
I propose to have a comprehensive specialist topic covering the roles that noncoding RNA play in innate immunity. I believe ... Much work has been done to show that miRNA are key regulators of the innate immune system and this year alone there has been a ... Activation of the innate immune signaling pathways is a highly complex process resulting in the induction of inflammatory gene ... years it has been shown that noncoding RNA are major contributors to the control of gene expression within innate immunity. ...
  https://www.frontiersin.org/research-topics/2304/functions-of-noncoding-rna-in-innate-immunity
*  Pathogenesis and innate immunity against staphylococcal infections | Frontiers Research Topic
Third, the exact role of antibodies, CD4 T-cells and cells of the innate immunity arm in contributing to protection still needs ... invasion and biofilm formation on one hand and on their interaction with innate immunity on the other. ... Keywords: pathogenisis, immunity, staphyloccocal infection, Staphylococci, resistance Important Note: All contributions to this ...
  https://www.frontiersin.org/research-topics/4955/pathogenesis-and-innate-immunity-against-staphylococcal-infections