*  The roles of Synoviolin in immune tolerance and autoimmunity - Deyu Fang
Impaired T cell tolerance is the cause of all types of autoimmune diseases, which suffers more than 23 million Americans. Since ... The roles of Synoviolin in immune tolerance and autoimmunity Fang, Deyu Northwestern University at Chicago, Chicago, IL, United ... The roles of Synoviolin in immune tolerance and autoimmunity. Fang, Deyu / Northwestern University at Chicago. $379,464. ... Since Sir Frank Macfarlane Burnet first described immune tolerance in late 1950s and received the 1960 Nobel Prize in ...
  http://grantome.com/grant/NIH/R01-AI108634-01A1
*  Search
The development of tolerance is the result of active immune mechanisms and both development and maintenance of tolerance are ... The immune system also acts to ensure tolerance to 'self', to food and other environmental components, and to commensal ... immune maturation and immune responses. Through these mechanisms it is possible that nutrition early in life might affect later ... If the neonatal immune system is not able to down-regulate the pre-existing Th2 dominance effectively then an allergic ...
  https://www.cambridge.org/core/search?filters%5BauthorTerms%5D=Christoph%20Berthold&eventCode=SE-AU
*  Immune tolerance - Wikipedia
Immune Tolerance Network International Conference on Immune Tolerance Immune tolerance at the US National Library of Medicine ... Immune tolerance is important for normal physiology. Central tolerance is the main way the immune system learns to discriminate ... Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to ... see Immune response). Tolerance is classified into central tolerance or peripheral tolerance depending on where the state is ...
  https://en.wikipedia.org/wiki/Immune_tolerance
*  Short course immune induction therapy - Wikipedia
Immune tolerance is maintained by central and peripheral tolerance. During central tolerance, T-cells are selected in the ... Immune tolerance can be defined as the ability of the immune system to distinguish between self and non-self, or harmless and ... While autoimmunity is thought to result from the breakdown of central and peripheral tolerance, an undesirable immune responses ... These strategies employed the use of soluble peptide tolerance and oral peptide tolerance to great efficacy in experimental ...
  https://en.wikipedia.org/wiki/Short_course_immune_induction_therapy
*  Immune tolerance in pregnancy - Wikipedia
Immune tolerance in pregnancy or gestational/maternal immune tolerance is the absence of a maternal immune response against (in ... and a chronic insufficient tolerance may cause infertility. Other examples of insufficient immune tolerance in pregnancy are Rh ... The increased immune tolerance is believed to be a major contributing factor to an increased susceptibility and severity of ... immune tolerance towards) the fetus and placenta during pregnancy, which thus may be viewed as unusually successful allografts ...
  https://en.wikipedia.org/wiki/Immune_tolerance_in_pregnancy
*  Immune Tolerance Induction Study - Full Text View - ClinicalTrials.gov
Immune Tolerance Induction Study. The safety and scientific validity of this study is the responsibility of the study sponsor ... An Exploratory Study of the Safety and Efficacy of Immune Tolerance Induction (ITI) in Patients With Pompe Disease Who Have ... safety and clinical benefit of 2 Immune Tolerance Induction (ITI) regimens in combination with Myozyme. Eligible patients who ...
  https://clinicaltrials.gov/ct2/show/NCT00701701?cond=%22succinic+semialdehyde+dehydrogenase+deficiency%22+OR+%22brain+diseases%2C+metabolic%2C+inborn%22&rank=20
*  Research institute acquires Immune Tolerance Institute - CenterWatch News Online
Home » News » R&D Trends » Research institute acquires Immune Tolerance Institute Research institute acquires Immune Tolerance ... The David H. Murdock Research Institute (DHMRI) has acquired the Immune Tolerance Institute (ITI) as part of the North Carolina ... "Advancing immune science will lead to new approaches to investigate the biological mechanisms of disease and functional ... Institute's mission to accelerate the discovery and development of breakthrough treatments for a range of immune-related ...
  http://www.centerwatch.com/news-online/2011/06/13/research-institute-acquires-immune-tolerance-institute/
*  NIH Guide: COLLABORATIVE NETWORK FOR CLINICAL RESEARCH ON IMMUNE TOLERANCE
COLLABORATIVE NETWORK FOR CLINICAL RESEARCH ON IMMUNE TOLERANCE Release Date: January 22, 1999 RFP AVAILABLE: NIH-NIAID-DAIT-99 ... coordinate and manage a Collaborative Network for Clinical Research on Immune Tolerance. The goals of this Collaborative ... maintenance and loss of tolerance as an integral part of Network-sponsored clinical trials, as well as clinical trials ... design a long-term research agenda to accelerate the application of tolerogenic approaches for the treatment of multiple immune ...
  https://grants.nih.gov/grants/guide/notice-files/not99-008.html
*  Astellas sets up immune tolerance JV in $760m deal - PharmaTimes
760 million to create a new US-based firm focused on developing novel immune tolerance therapeutics. - News - PharmaTimes ... The firm will utilise Anokion's tolerance-inducing technology shown to induce immune tolerance to protein drugs and autoimmune ... Astellas sets up immune tolerance JV in $760m deal. 3rd June 2015. ... 760 million to create a new US-based firm focused on developing novel immune tolerance therapeutics. ...
  http://www.pharmatimes.com/news/astellas_sets_up_immune_tolerance_jv_in_$760m_deal_971466
*  Patente US9295756 - Methods for inducing immune tolerance to organ transplants - Google Patentes
The immune tolerance is achieved by selective ablation of the inner lining of the blood vessels of the organ or tissue, in a ... Accordingly, the present invention relates to novel methods for inducing immune tolerance to tissue or organ transplants by ... Methods for inducing immune tolerance to organ transplants. ... Methods for inducing immune tolerance to organ transplants. US ... For example, the tolerance may be assessed by monitoring subject-specific leukocyte or T-lymphocyte infiltration of the graft, ...
  http://www.google.es/patents/US9295756
*  Uncovering the role of the placenta in pregnancy immune tolerance - AgBioResearch
Margaret Petroff believes that decoding additional secrets to immune tolerance could lead to treatment breakthroughs for a ... His research eventually homed in on immune tolerance, the biological process that allows the host's immune system to accept ... "If we can better understand the function of the placenta during pregnancy and how that promotes immune tolerance, we can combat ... Uncovering the role of the placenta in pregnancy immune tolerance. Margaret Petroff believes that decoding additional secrets ...
  http://www.canr.msu.edu/news/uncovering-the-role-of-the-placenta-in-pregnancy-immune-tolerance
*  Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance. | Sigma-Aldrich
Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance.. [Takatoshi Chinen, Kyoko Komai, Go Muto, Rimpei Morita ... Here, we identify suppressor of cytokine signalling 1 (SOCS1) as an essential mediator of immune tolerance in the intestine. ... Additionally, we find an essential role for prostaglandin E2 (PGE2) in the maintenance of tolerance within the intestine in the ... Thus, we propose that SOCS1 and PGE2, potentially interacting together, act as an alternative intestinal tolerance mechanism ...
  https://www.sigmaaldrich.com/catalog/papers/21304519
*  Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance | The Journal of Immunology
Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance. Motonari Kondo, Yuriko Tanaka, Taku Kuwabara, ... Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance. Motonari Kondo, Yuriko Tanaka, Taku Kuwabara, ... Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance Message Subject (Your Name) has forwarded a page ... Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance. Motonari Kondo, Yuriko Tanaka, Taku Kuwabara, ...
  http://www.jimmunol.org/content/196/8/3495
*  Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes | Diabetes
Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes ... Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes ... Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes ... Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes ...
  http://diabetes.diabetesjournals.org/content/early/2011/02/07/db10-1360.short?rss=1
*  JCI Insight - Goblet cell loss abrogates ocular surface immune tolerance
Conjunctival immune tolerance suppresses expansion of OVA-specific T cells in vitro. CD4+ T cells isolated from spleens (SPL) ... The immune tolerance to OVA antigen topically applied to the conjunctiva measured by cutaneous delayed type hypersensitivity ( ... Conjunctival immune tolerance was measured by delayed type hypersensitivity (DTH) to OVA using the following protocol: OVA ... We hypothesized that loss of GCs reduces tolerance-inducing properties of antigen presenting cells (APCs) in the conjunctiva ...
  https://insight.jci.org/articles/view/98222/figure/4
*  Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents - Full...
Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents. The ... Knowledge of these properties would support the need for specific IS therapy to promote immune tolerance and consider IS ... Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents. ... comparing immune tolerance and alloreactivity profiles in LT recipients on monotherapy IS or converted to rapamycin monotherapy ...
  https://clinicaltrials.gov/ct2/show/NCT01678937
*  Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA - Full Text View - ClinicalTrials.gov
Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA (ABPA). The safety and scientific ... To test the hypothesis that surface-bound TGF beta is critical for the development and maintenance of immune tolerance to A. ... SCCOR in Host Factors in Chronic Lung Diseases: Mechanisms of Immune Tolerance and Inflammation in Allergic Bronchopulmonary ...
  https://clinicaltrials.gov/ct2/show/NCT00585364
*  Role of diet in the development of immune tolerance in the context of allergic disease
... West, Christina E Umeå University, ... Rather there is focus on their role in tolerance induction. SUMMARY: Modern dietary changes are clearly implicated in the ... Here, we explore the effects of key perinatal dietary exposures on immune development and susceptibility to allergic disease. ... These dietary changes, which appear to be providing less tolerogenic conditions during early immune programming, may provide ...
  http://umu.diva-portal.org/smash/record.jsf?pid=diva2:355813
*  Pregnancy Associated with Systemic Lupus Erythematosus: Immune Tolerance in Pregnancy and Its Deficiency in Systemic Lupus...
... immune pathology, immunodeficiency, autoimmune diseases, immune disorders, and immunotherapy. ... Pregnancy Associated with Systemic Lupus Erythematosus: Immune Tolerance in Pregnancy and Its Deficiency in Systemic Lupus ... "Regulatory T helper cells in pregnancy and their roles in systemic versus local immune tolerance," The American Journal of ... G. Mor and I. Cardenas, "The immune system in pregnancy-a unique complexity," The American Journal of Reproductive Immunology, ...
  https://www.hindawi.com/journals/jir/2015/241547/ref/
*  Immune Tolerance Induction with Multiepitope Peptide Derived from Citrullinated Autoantigens Attenuates Arthritis...
Immune Tolerance Induction with Multiepitope Peptide Derived from Citrullinated Autoantigens Attenuates Arthritis ... Immune Tolerance Induction with Multiepitope Peptide Derived from Citrullinated Autoantigens Attenuates Arthritis ... Immune Tolerance Induction with Multiepitope Peptide Derived from Citrullinated Autoantigens Attenuates Arthritis ... Immune Tolerance Induction with Multiepitope Peptide Derived from Citrullinated Autoantigens Attenuates Arthritis ...
  http://www.jimmunol.org/content/early/2015/05/09/jimmunol.1402457
*  Searching For The Secrets Of Drug-Free Transplants: University Of Pittsburgh, Through Immune Tolerance Network, To Develop...
Through Immune Tolerance Network, To Develop Tests Predictive Of Transplant Tolerance ... searching-secrets-drug-free-transplants-university-pittsburgh-immune-tolerance-network-develop-tests-transplant-tolerance ... Through Immune Tolerance Network, To Develop Tests Predictive Of Transplant Tolerance. PITTSBURGH, November 1, 2000 - ... Transplant tolerance, which refers to the state by which a patient's immune system has fully accepted a transplanted organ, is ...
  http://www.upmc.com/media/newsreleases/2000/pages/searching-secrets-drug-free-transplants-university-pittsburgh-immune-tolerance-network-develop-tests-transplant-tolerance.aspx
*  Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and...
Taken together, our data suggest that ABMT restores immune tolerance by renewal and modulation of the Teff cell compartment, ... Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and ...
  https://www.sigmaaldrich.com/catalog/papers/24504807
*  David H. Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human...
Immune,Tolerance,Institute,and,Establishes,a,State,of,the,Art,Human,Immune,Monitoring,Laboratory,for,Biomarker,Discovery,and, ... Advancing immune science will lead to new approaches to investigate t...,David,H.,Murdock,Research,Institute,Assumes,Control,of ... Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human Immune ... The Immune Tolerance Institute (ITI) is a 501 (c)(3) non-profit corporation founded to fill critical unmet needs for ...
  http://www.bio-medicine.org/biology-technology-1/David-H--Murdock-Research-Institute-Assumes-Control-of-the-Immune-Tolerance-Institute-and-Establishes-a-State-of-the-Art-Human-Immune-Monitoring-Labor-19675-1/
*  Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs - Zurich Open Repository and Archive
Akdis, Cezmi A; Akdis, Mübeccel (2014). Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs. Journal of ... The demonstration of T cell tolerance, particularly that mediated by the immune-suppressive functions of IL-10, led to a major ... The demonstration of T cell tolerance, particularly that mediated by the immune-suppressive functions of IL-10, led to a major ... Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs ...
  http://www.zora.uzh.ch/id/eprint/103523/
*  Norges idrettshøgskole
Gene expression is differentially regulated in skeletal muscle and circulating immune cells in response to an acute bout of ... on improvement of glycemia may differ between prediabetic individuals defined by oral glucose tolerance test vs glycated ...
  https://brage.bibsys.no/xmlui/handle/11250/170397