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*  Muscle - Wikipedia
... where they fuse into elongate skeletal muscle cells. The three types of muscle (skeletal, cardiac and smooth) have significant ... Muscle Architecture and Muscle Fiber Anatomy". Skeletal Muscle: Form and Function (2nd ed.). Champaign, IL: Human Kinetics. pp ... However, all three use the movement of actin against myosin to create contraction. In skeletal muscle, contraction is ... There are three types of muscle, skeletal or striated, cardiac, and smooth. Muscle action can be classified as being either ...
  https://en.wikipedia.org/wiki/Muscle
*  Human Physiology/The Muscular System - Wikibooks, open books for an open world
There are three basic types of muscles in the body (smooth, cardiac, and skeletal). While they differ in many regards, they all ... When a muscle contracts, the actin is pulled along myosin toward the center of the sarcomere until the actin and myosin ... There are three general types of muscle contractions, skeletal muscle contractions, heart muscle contractions, and smooth ... Cardiac muscle is found in the heart and lungs of humans. ATP in the Human Body[edit]. Muscles cells, like all cells, use ATP ...
  https://en.wikibooks.org/wiki/Human_Physiology/The_Muscular_System
*  Human Muscle
... each composed of a single muscle cell. As shown in Figure 27-2, a muscle cell contains a series of ultramicrosc ... Muscle is made up of thousands of muscle fibers, ... Types of muscle. The human body has three major types of muscle ... In skeletal muscle, the overlapping actin and myosin filaments give the muscle fiber a banded, or striated, appearance. Hence, ... The third muscle type is cardiac muscle, which is found in the heart. It has striations because it has multiple actin and ...
  https://www.cliffsnotes.com/study-guides/biology/biology/support-and-movement-in-animals/human-muscle
*  Myosin Gene Expression and Cell Phenotypes in Vascular Smooth Muscle During Development, in Experimental Models, and in...
1 All three proteins, however, are transiently present in embryonic cardiac and skeletal muscle, although during later ... The adult human pulmonary artery is distinct from the aorta owing to the presence of an additional SM-type isoform of ≈190 kD ( ... Chiavegato A, Pauletto P, Sartore S. Smooth muscle-type myosin heavy chain isoforms in bovine smooth muscle and non-muscle ... myosin heavy chain B)- and platelet (myosin heavy chain Apla)-type nonmuscle myosins. Using the myosin isoform approach to ...
  http://atvb.ahajournals.org/content/17/7/1210
*  Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits | SpringerLink
Improving human skeletal muscle myosin heavy chain fiber typing efficiency. J Muscle Res Cell MotilGoogle Scholar ... Fagard R, Van Den Broeke C, Bielen E, Amery A (1987) Maximum oxygen uptake and cardiac size and function in twins. Am J Cardiol ... Simoneau JA, Bouchard C (1995) Genetic determinism of fiber type proportion in human skeletal muscle. FASEB J 9(11):1091-1095 ... Skeletal muscle fatigability and myosin heavy chain fiber type in resistance trained Men. J Strength Cond Res 31(3):602-607 ...
  https://link.springer.com/article/10.1007%2Fs00421-018-3943-7
*  WikiGenes - MYH1 - myosin, heavy chain 1, skeletal muscle, adult
Three major MyHC isoforms are expressed in human skeletal muscle (type I, MYH7, expressed in type 1 fibres; IIa, MYH2, ... The conventional myosin motor proteins that drive mammalian skeletal and cardiac muscle contraction include eight sarcomeric ... Immunohistochemistry was supportive of skeletal muscle differentiation with at least one positive skeletal muscle-specific ... Cardiac myosin binding protein C gene is specifically expressed in heart during murine and human development. Fougerousse, F., ...
  https://www.wikigenes.org/e/gene/e/4619.html
*  MYL4 - Wikipedia
"A novel human myosin alkali light chain is developmentally regulated. Expression in fetal cardiac and skeletal muscle and in ... "The N-terminus of A1-type myosin essential light chains binds actin and modulates myosin motor function". European Journal of ... "Three-dimensional structure of myosin subfragment-1: a molecular motor". Science. 261 (5117): 50-8. doi:10.1126/science.8316857 ... ALC-1 is expressed very early in skeletal muscle and cardiac muscle development; two E-boxes and CArG box in the MYL4 promoter ...
  https://en.wikipedia.org/wiki/MYL4
*  A case of reversible cardiomyopathy & left ventricular noncompaction
The myosin heavy chain genes encode the two contractile proteins of the thick filament in the cardiac myocyte. These two ... Whereas D1 is primarily expressed in the liver and kidneys, D2 is present in other tissues including the human heart and muscle ... Deiodination of T4 to T3 is catalyzed by three types of deiodinases; D1, D2 and D3 [5]. These oxido-reductases differ in their ... Thyroxin is converted to T3 by monodeiodination in the liver, kidney and skeletal muscle. The heart relies mainly on T3 ...
  https://www.oatext.com/A-case-of-reversible-cardiomyopathy-left-ventricular-noncompaction.php
*  What is the difference between relaxed and contracted sarcomere? | Reference.com
Relaxed sarcomeres contain myosin heads that have released their pull on the thin filaments. This allows them to return back to ... Filaments are muscle fibers. Muscle fibers can be divided into three types. The skeletal muscle fibers move the bones and limbs ... Where can you find a diagram of human neck muscles?. * Q: How does a skeletal muscle twitch differ from a tetanic contraction? ... Smooth muscle fibers surround blood vessels and all organs except the heart. The heart contains cardiac fibers. Muscle fibers ...
  https://www.reference.com/science/difference-between-relaxed-contracted-sarcomere-6f0692cf086575e4
*  Two novel MYH7 proline substitutions cause Laing Distal Myopathy-like phenotypes with variable expressivity and neck extensor...
Background Human skeletal muscles express three major myosin heavy chain (MyHC) isoforms: MyHCIIx (MYH1) in fast type 2B muscle ... in fast type 2A fibers and MyHCI/β-cardiac MyHC (MYH7) in slow type I skeletal fibers and cardiac ventricles. In line with its ... expression pattern, MYH7 mutations have been reported in association with hypertrophic or dilated cardiomyopathy, skeletal ...
  https://scholars.bgu.ac.il/display/n598162
*  Recombinant Human Cardiac Troponin I (TnI) · QED Bioscience Inc
TnI acts as the inhibitory subunit by blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The ... skeletal-fast-twitch, TnI-skeletal-slow- twitch, and TnI-cardiac. The TNNI3 gene encodes the TnI-cardiac protein and is ... exclusively expressed in cardiac muscle tissue. Mutations in the TNNI3 gene cause familial hypertrophic cardiomyopathy type 7 ... Recombinant Human TnI produced in E. coli is a single, non-glycosylated polypeptide chain containing 165 amino acids with a ...
  https://www.qedbio.com/product/recombinant-human-cardiac-troponin-i-tni/
*  Myofilament - Wikipedia
Types of muscle are striated muscle (such as skeletal muscle and cardiac muscle), obliquely striated muscle (found in some ... In striated muscle, such as skeletal and cardiac muscle, the actin and myosin filaments each have a specific and constant ... Smooth muscle has irregular arrangements of filaments. There are three different types of myofilaments: thick, thin, and ... a few millimeters in the case of human skeletal muscle cells). The filaments are organized into repeated subunits along the ...
  https://en.wikipedia.org/wiki/Myofilament
*  What Is the Structure of Skeletal Muscles? (with pictures)
The structure of skeletal muscles consists of two overlapping proteins that give it a striped appearance. Each muscle has long ... Three kinds of muscle tissue, including the skeletal, cardiac, and smooth muscles, make up the human muscular system. Skeletal ... The structure of skeletal muscles is slightly different from the other two main types of muscles, cardiac and smooth muscles. ... As seen under a microscope, dark bands formed by myosin overlap light bands formed by actin, resulting in the striped ...
  http://www.wisegeek.com/what-is-the-structure-of-skeletal-muscles.htm
*  anti-Cardiac Troponin I antibody [MF4] | GeneTex
... cardiac)) for Apuri, ELISA, WB. Anti-Cardiac Troponin I mAb (GTX10239) is tested in Human, Mouse, Dog, Pig, Rat, Cat, Goat, ... Cardiac Troponin I antibody [MF4] (troponin I type 3 ( ... in cardiac muscles in different forms than in skeletal muscles ... troponin I type 3 (cardiac). Background. Troponin I is part of a heteromeric complex playing an important role in the ... regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and ...
  http://www.genetex.com/Cardiac-Troponin-I-antibody-MF4-GTX10239.html
*  Troponin - Wikipedia
TnC in human cardiac muscle tissue is presented by an isoform typical for slow skeletal muscle. Another form of TnC, fast ... April 2001). "Cardiac troponin and beta-type myosin heavy chain concentrations in patients with polymyositis or dermatomyositis ... whereas in cardiac muscle there are only three. Views on the actual amount of calcium that binds to troponin vary from expert ... that is integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle . Discussions of troponin ...
  https://en.wikipedia.org/wiki/Troponin
*  MYBPC1 - Wikipedia
"Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C). Differential expression, conserved ... with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain". J. Biol. Chem. 272 (33): 20866-72. doi ... 1995). "[IMAGE: molecular integration of the analysis of the human genome and its expression]". C. R. Acad. Sci. III, Sci. Vie ... "Entrez Gene: MYBPC1 myosin binding protein C, slow type". Fürst DO, Vinkemeier U, Weber K (1992). "Mammalian skeletal muscle C- ...
  https://en.wikipedia.org/wiki/MYBPC1
*  Antibodies to Actin and GAPDH | Sigma-Aldrich
There are three α-actins (skeletal, cardiac, and smooth muscle), one β-actin (β-nonmuscle), and two γ-actins (γ-smooth muscle ... Actin and myosin are the two major cytoskeletal proteins implicated in cell motility. As constituents of many cell types, actin ... Human Actin Gene Family. Immunoblotting Chicken fi broblast cells extract was separated on SDS-PAGE and probed with Monoclonal ... Immunoblotting Rat skeletal muscle and HeLa total cell extract were separated on SDS-PAGE and probed with monoclonal AIA to ...
  https://www.sigmaaldrich.com/technical-documents/articles/biofiles/antibodies-to-actin.html
*  Increased Expression of Isoform 1 of the Sarcoplasmic Reticulum Ca2+-Release Channel in Failing Human Heart | Circulation
... release and skeletal muscle-type excitation-contraction coupling. Isoform 2 of the SR Ca2+-release channel is expressed ... channel is in agreement with the isoform shifts in cardiac failure previously described for contractile proteins such as myosin ... IgG antibodies for use with monoclonal type 1 and type 2 antibodies and goat IgG antibodies used for polyclonal type 1 and type ... release channel in human cardiac myocytes could be determined in human myocardial tissue. Figure 8⇓ shows histological details ...
  http://circ.ahajournals.org/content/103/22/2739
*  Computational identification of phosphorylation sites around nuclear localization signal sequence reveals new insight into...
... of the NLS phosphorylation status of these genes in clinical samples may lead to development of new biomarkers for human ... Alterations in protein Subcellular localization often contribute to the development of human diseases. Post-transcriptional ... Myopathy, Myosin Storage. 0.60. Genetic Variation. MYH8. myosin, heavy chain 8, skeletal muscle, perinatal. ... troponin T type 2 (cardiac). 182RKKKALsNMMHFGGy. IQKQAQtERKsGKRQtEREK. KKK220. S189; Y197; T213. ardiomyopathy, Dilated, 1D. ...
  https://www.ommegaonline.org/article-details/Computational-identification-of-phosphorylation-sites-around-nuclear-localization-signal-sequence-reveals-new-insight-into-genes-associated-with-human-diseases/1217
*  Isoform Composition and Gene Expression of Thick and Thin Filament Proteins in Striated Muscles of Mice after 30-Day Space...
A muscle fibre-type shift from slow-to-fast and a decrease in the content of titin and nebulin in the skeletal muscles of ... Atrophic and morphological changes were observed in cardiac muscles of humans and animals after their exposure to conditions of ... However, our RT-PCR results showed an increase in the expression of gene for titin in all the three skeletal muscles of flight ... modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle ...
  https://www.hindawi.com/journals/bmri/2015/104735/
*  Muscle - Wikipedia
The body contains three types of muscle tissue: (a) skeletal muscle, (b) smooth muscle, and (c) cardiac muscle. (Same ... Muscle Architecture and Muscle Fiber Anatomy". Skeletal Muscle: Form and Function (2nd ed.). Champaign, IL: Human Kinetics. pp ... However, all three use the movement of actin against myosin to create contraction. In skeletal muscle, contraction is ... There are three types of muscle, skeletal or striated, cardiac, and smooth. Muscle action can be classified as being either ...
  https://en.m.wikipedia.org/wiki/Muscle
*  MYBPC2 - Wikipedia
"Support for a trimeric collar of myosin binding protein C in cardiac and fast skeletal muscle, but not in slow skeletal muscle ... Weber FE, Vaughan KT, Reinach FC, Fischman DA (Sep 1993). "Complete sequence of human fast-type and slow-type muscle myosin- ... Myosin binding protein C, fast type is a protein that in humans is encoded by the MYBPC2 gene. This gene encodes a member of ... This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the ...
  https://en.wikipedia.org/wiki/MYBPC2
*  Troponin I Type 3 (cardiac) Antibody (P37-3) (NB120-20119): Novus Biologicals
... cardiac) Antibody (P37-3). Validated: WB, IA. Tested Reactivity: Human. 100% Guaranteed. ... TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal ... This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are ... cardiac). Troponin I is part of a heteromeric thin filament regulatory complex that governs skeletal and cardiac muscle ...
  https://www.novusbio.com/products/troponin-i-type-3-cardiac-antibody-p37-3_nb120-20119
*  TNNT2 - Wikipedia
TNNT2 gene is expressed in vertebrate cardiac muscles and embryonic skeletal muscles. Cardiac TnT is a 35.9 kDa protein ... Three homologous genes have evolved in vertebrates encoding three muscle type- specific isoforms of TnT. Each of the TnT ... Cardiac muscle troponin T (cTnT), is a protein which in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin- ... leading to attenuation of the myofilament force production by decreasing the myosin ATPase activity. In cardiac muscle under ...
  https://en.wikipedia.org/wiki/TNNT2
*  Myosin binding protein C, cardiac - Wikipedia
... cardiac-type is a protein that in humans is encoded by the MYBPC3 gene. This isoform is expressed exclusively in heart muscle ... The cMyBP-C isoform expressed in cardiac muscle differs from those expressed in slow and fast skeletal muscle (MYBPC1 and ... cardiac hypertrophy. The human c.772G>A transition results in low levels of three different mutant Mybpc3 mRNAs and cMyBP-Cs in ... "Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain ...
  https://en.wikipedia.org/wiki/Myosin_binding_protein_C,_cardiac