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*  Human Physiology/The Muscular System - Wikibooks, open books for an open world
There are three basic types of muscles in the body (smooth, cardiac, and skeletal). While they differ in many regards, they all ... When a muscle contracts, the actin is pulled along myosin toward the center of the sarcomere until the actin and myosin ... There are three general types of muscle contractions, skeletal muscle contractions, heart muscle contractions, and smooth ... Cardiac muscle is found in the heart and lungs of humans. ATP in the Human Body[edit]. Muscles cells, like all cells, use ATP ...
  https://en.wikibooks.org/wiki/Human_Physiology/The_Muscular_System
*  Muscle - Wikipedia
... where they fuse into elongate skeletal muscle cells. The three types of muscle (skeletal, cardiac and smooth) have significant ... Muscle Architecture and Muscle Fiber Anatomy". Skeletal Muscle: Form and Function (2nd ed.). Champaign, IL: Human Kinetics. pp ... However, all three use the movement of actin against myosin to create contraction. In skeletal muscle, contraction is ... There are three types of muscle, skeletal or striated, cardiac, and smooth. Muscle action can be classified as being either ...
  https://en.wikipedia.org/wiki/Muscle
*  Human Muscle
... each composed of a single muscle cell. As shown in Figure 27-2, a muscle cell contains a series of ultramicrosc ... Muscle is made up of thousands of muscle fibers, ... Types of muscle. The human body has three major types of muscle ... In skeletal muscle, the overlapping actin and myosin filaments give the muscle fiber a banded, or striated, appearance. Hence, ... The third muscle type is cardiac muscle, which is found in the heart. It has striations because it has multiple actin and ...
  https://www.cliffsnotes.com/study-guides/biology/biology/support-and-movement-in-animals/human-muscle
*  Myosin Gene Expression and Cell Phenotypes in Vascular Smooth Muscle During Development, in Experimental Models, and in...
1 All three proteins, however, are transiently present in embryonic cardiac and skeletal muscle, although during later ... The adult human pulmonary artery is distinct from the aorta owing to the presence of an additional SM-type isoform of ≈190 kD ( ... Chiavegato A, Pauletto P, Sartore S. Smooth muscle-type myosin heavy chain isoforms in bovine smooth muscle and non-muscle ... myosin heavy chain B)- and platelet (myosin heavy chain Apla)-type nonmuscle myosins. Using the myosin isoform approach to ...
  http://atvb.ahajournals.org/content/17/7/1210
*  What is the difference between relaxed and contracted sarcomere? | Reference.com
Relaxed sarcomeres contain myosin heads that have released their pull on the thin filaments. This allows them to return back to ... Filaments are muscle fibers. Muscle fibers can be divided into three types. The skeletal muscle fibers move the bones and limbs ... Where can you find a diagram of human neck muscles?. * Q: How does a skeletal muscle twitch differ from a tetanic contraction? ... Smooth muscle fibers surround blood vessels and all organs except the heart. The heart contains cardiac fibers. Muscle fibers ...
  https://www.reference.com/science/difference-between-relaxed-contracted-sarcomere-6f0692cf086575e4
*  MYL4 - Wikipedia
"A novel human myosin alkali light chain is developmentally regulated. Expression in fetal cardiac and skeletal muscle and in ... "The N-terminus of A1-type myosin essential light chains binds actin and modulates myosin motor function". European Journal of ... "Three-dimensional structure of myosin subfragment-1: a molecular motor". Science. 261 (5117): 50-8. doi:10.1126/science.8316857 ... ALC-1 is expressed very early in skeletal muscle and cardiac muscle development; two E-boxes and CArG box in the MYL4 promoter ...
  https://en.wikipedia.org/wiki/MYL4
*  What Is the Structure of Skeletal Muscles? (with pictures)
The structure of skeletal muscles consists of two overlapping proteins that give it a striped appearance. Each muscle has long ... Three kinds of muscle tissue, including the skeletal, cardiac, and smooth muscles, make up the human muscular system. Skeletal ... The structure of skeletal muscles is slightly different from the other two main types of muscles, cardiac and smooth muscles. ... As seen under a microscope, dark bands formed by myosin overlap light bands formed by actin, resulting in the striped ...
  http://www.wisegeek.com/what-is-the-structure-of-skeletal-muscles.htm
*  Myofilament - Wikipedia
Types of muscle are striated muscle (such as skeletal muscle and cardiac muscle), obliquely striated muscle (found in some ... In striated muscle, such as skeletal and cardiac muscle, the actin and myosin filaments each have a specific and constant ... Smooth muscle has irregular arrangements of filaments. There are three different types of myofilaments: thick, thin, and ... a few millimeters in the case of human skeletal muscle cells). The filaments are organized into repeated subunits along the ...
  https://en.wikipedia.org/wiki/Myofilament
*  Increased Expression of Isoform 1 of the Sarcoplasmic Reticulum Ca2+-Release Channel in Failing Human Heart | Circulation
... release and skeletal muscle-type excitation-contraction coupling. Isoform 2 of the SR Ca2+-release channel is expressed ... channel is in agreement with the isoform shifts in cardiac failure previously described for contractile proteins such as myosin ... IgG antibodies for use with monoclonal type 1 and type 2 antibodies and goat IgG antibodies used for polyclonal type 1 and type ... release channel in human cardiac myocytes could be determined in human myocardial tissue. Figure 8⇓ shows histological details ...
  http://circ.ahajournals.org/content/103/22/2739
*  Antibodies to Actin and GAPDH | Sigma-Aldrich
There are three α-actins (skeletal, cardiac, and smooth muscle), one β-actin (β-nonmuscle), and two γ-actins (γ-smooth muscle ... Actin and myosin are the two major cytoskeletal proteins implicated in cell motility. As constituents of many cell types, actin ... Human Actin Gene Family. Immunoblotting Chicken fi broblast cells extract was separated on SDS-PAGE and probed with Monoclonal ... Immunoblotting Rat skeletal muscle and HeLa total cell extract were separated on SDS-PAGE and probed with monoclonal AIA to ...
  https://www.sigmaaldrich.com/technical-documents/articles/biofiles/antibodies-to-actin.html
*  MYBPC1 - Wikipedia
"Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C). Differential expression, conserved ... with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain". J. Biol. Chem. 272 (33): 20866-72. doi ... 1995). "[IMAGE: molecular integration of the analysis of the human genome and its expression]". C. R. Acad. Sci. III, Sci. Vie ... "Entrez Gene: MYBPC1 myosin binding protein C, slow type". Fürst DO, Vinkemeier U, Weber K (1992). "Mammalian skeletal muscle C- ...
  https://en.wikipedia.org/wiki/MYBPC1
*  Muscle - Wikipedia
The body contains three types of muscle tissue: (a) skeletal muscle, (b) smooth muscle, and (c) cardiac muscle. (Same ... Muscle Architecture and Muscle Fiber Anatomy". Skeletal Muscle: Form and Function (2nd ed.). Champaign, IL: Human Kinetics. pp ... However, all three use the movement of actin against myosin to create contraction. In skeletal muscle, contraction is ... There are three types of muscle, skeletal or striated, cardiac, and smooth. Muscle action can be classified as being either ...
  https://en.m.wikipedia.org/wiki/Muscle
*  Troponin I Type 3 (cardiac) Antibody (P37-3) (NB120-20119): Novus Biologicals
... cardiac) Antibody (P37-3). Validated: WB, IA. Tested Reactivity: Human. 100% Guaranteed. ... TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal ... This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are ... cardiac). Troponin I is part of a heteromeric thin filament regulatory complex that governs skeletal and cardiac muscle ...
  https://www.novusbio.com/products/troponin-i-type-3-cardiac-antibody-p37-3_nb120-20119
*  Angiotensin II Induces Cardiac Phenotypic Modulation and Remodeling In Vivo in Rats | Hypertension
Mayer Y, Czosnek H, Zeelon PE, Yaffe D, Nudel U. Expression of the genes coding for the skeletal muscle and cardiac actins in ... Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts. J Biol Chem. ... Typical autoradiograms of Northern blot analysis of left ventricular mRNAs for skeletal α-actin, cardiac α-actin, α-myosin ... Cardiac hypertrophy is a major risk factor for heart failure in humans.1 2 Previous in vivo studies have shown that inhibitors ...
  http://hyper.ahajournals.org/content/25/6/1252?ijkey=fc355b0b00cfa7b0f95802bc159564a09f7bfc6f&keytype2=tf_ipsecsha
*  MYBPC2 - Wikipedia
"Support for a trimeric collar of myosin binding protein C in cardiac and fast skeletal muscle, but not in slow skeletal muscle ... Weber FE, Vaughan KT, Reinach FC, Fischman DA (Sep 1993). "Complete sequence of human fast-type and slow-type muscle myosin- ... Myosin binding protein C, fast type is a protein that in humans is encoded by the MYBPC2 gene. This gene encodes a member of ... This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the ...
  https://en.wikipedia.org/wiki/MYBPC2
*  Troponin - Wikipedia
TnC in human cardiac muscle tissue is presented by an isoform typical for slow skeletal muscle. Another form of TnC, fast ... April 2001). "Cardiac troponin and beta-type myosin heavy chain concentrations in patients with polymyositis or dermatomyositis ... whereas in cardiac muscle there are only three. Views on the actual amount of calcium that binds to troponin vary from expert ... that is integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle . Discussions of troponin ...
  https://en.wikipedia.org/wiki/Troponin
*  TNNT2 - Wikipedia
TNNT2 gene is expressed in vertebrate cardiac muscles and embryonic skeletal muscles. Cardiac TnT is a 35.9 kDa protein ... Three homologous genes have evolved in vertebrates encoding three muscle type- specific isoforms of TnT. Each of the TnT ... Cardiac muscle troponin T (cTnT), is a protein which in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin- ... leading to attenuation of the myofilament force production by decreasing the myosin ATPase activity. In cardiac muscle under ...
  https://en.wikipedia.org/wiki/TNNT2
*  Muscular system - Wikipedia
... which is responsible for movement of the human body. There are three distinct types of muscles: skeletal muscles, cardiac or ... Myosin filaments have club-shaped heads that project toward the actin filaments. Larger structures along the myosin filament ... There are approximately 639 skeletal muscles in the human body. Skeletal muscles, viewed from the front Skeletal muscles, ... Skeletal muscles, like other striated muscles, are composed of myocytes, or muscle fibers, which are in turn composed of ...
  https://en.wikipedia.org/wiki/Muscular_system
*  Musculoskeletal System
... which pass a threshold to produce a muscle twitch.There are three types of muscles involved: smooth, cardiac and skeletal. ... Human Biology: Multiple choice questions on muscles and bones. 1. The basic unit of contraction is the a. myosin b. actin c. Z- ... Muscle Types. What are the similarities and differences between Skeletal Muscle, Cardiac Muscle and Smooth Muscle?. ... Skeletal muscles are connected to the human skeleton by tendons, theses muscles are voluntary and are controlled by the somatic ...
  https://brainmass.com/biology/musculoskeletal-system
*  Skeletal muscle | anatomy | Britannica.com
Skeletal muscle, in vertebrates, most common of the three types of muscle in the body. Skeletal muscles are attached to bones ... Unlike smooth muscle and cardiac muscle, skeletal muscle is under voluntary control. Similar to cardiac muscle, however, ... For more information on the structure and function of skeletal muscle, see muscle and muscle system, human. ... Within each myofibril are filaments of the proteins myosin and actin; these filaments slide past one another as the muscle ...
  https://www.britannica.com/science/skeletal-muscle
*  Cardiotrophin-1 in Heart Failure | Circulation
CT-1 is also expressed in adult skeletal muscle, ovary, colon, prostate, and testis and in fetal kidney and lung.2 When ... 5 which suggests a role for CT-1 or other IL-6-type cytokines in normal cardiac development. However, mice with ventricular ... Fetal gene induction in the failing human heart is under partial β1-adrenergic control,17 and so β-adrenergic stimulation of CT ... myosin light chain 2 promoter that drives a Cre/lox recombination/knockout system from early in development have no cardiac ...
  http://circ.ahajournals.org/content/106/12/1430
*  Troponin C type 1 - Wikipedia
Troponin C is encoded by the TNNC1 gene in humans for both cardiac and slow skeletal muscle. Cardiac troponin C (cTnC) is a 161 ... allowing actin-myosin cross-bridging and muscle contraction to proceed. Strong actin-myosin interaction can further shift the ... "Entrez Gene: TNNC1 troponin C type 1 (slow)". "Troponin C, slow skeletal and cardiac muscles". Cardiac Organellar Protein Atlas ... In cardiac muscle, cTnC binds to cardiac troponin I (cTnI) and cardiac troponin T (cTnT), whereas cTnC binds to slow skeletal ...
  https://en.wikipedia.org/wiki/Troponin_C_type_1
*  Myosin binding protein C, cardiac - Wikipedia
... cardiac-type is a protein that in humans is encoded by the MYBPC3 gene. This isoform is expressed exclusively in heart muscle ... The cMyBP-C isoform expressed in cardiac muscle differs from those expressed in slow and fast skeletal muscle (MYBPC1 and ... cardiac hypertrophy. The human c.772G>A transition results in low levels of three different mutant Mybpc3 mRNAs and cMyBP-Cs in ... "Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain ...
  https://en.wikipedia.org/wiki/Myosin_binding_protein_C,_cardiac
*  Development of a porcine skeletal muscle cDNA microarray: analysis of differential transcript expression in phenotypically...
Lim DS, Roberts R, Marian AJ: Expression profiling of cardiac genes in human hypertrophic cardiomyopathy: insight into the ... have 4 major fibre types characterised by the expression of the slow/β, 2a, 2x and 2b myosin heavy chain (MyHC) gene isoforms [ ... Results of pooled total cDNA samples from three 22-week-old Berkshire pigs. GAPDH and MyHC 2b were about 2.7 and 2.5 times more ... a group of 4080 human skeletal muscle genes, which included both skeletal muscle-specific genes and genes expressed in skeletal ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-4-8
*  Myosin - Wikipedia
Myosin II (also known as conventional myosin) is the myosin type responsible for producing muscle contraction in muscle cells. ... A human homologue gene for myosin III, MYO3A, has been uncovered through the Human Genome Project and is expressed in the ... Skeletal muscle myosin, the most conspicuous of the myosin superfamily due to its abundance in muscle fibers, was the first to ... Similar filament-forming myosin proteins were found in cardiac muscle, smooth muscle, and nonmuscle cells. However, beginning ...
  https://en.wikipedia.org/wiki/Myosin