HMG CoA Reductase Inhibitors Reduce Plasminogen Activator Inhibitor-1 Expression by Human Vascular Smooth Muscle and...
HMG CoA Reductase Inhibitors Reduce Plasminogen Activator Inhibitor-1 Expression by Human Vascular Smooth Muscle and ... "HMG CoA Reductase Inhibitors Reduce Plasminogen Activator Inhibitor-1 Expression by Human Vascular Smooth Muscle and ... plasminogen activator inhibitor-1 (PAI-1), and tissue-type plasminogen activator (tPA) in human vascular smooth muscle (SMC) ... The clinical benefit of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) may derive from a qualitative, ...https://dash.harvard.edu/handle/1/12760261
Induction of insulin resistance by the adipokines resistin, leptin, plasminogen activator inhibitor-1 and retinol binding...
2004) Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets. Blood 104(6 ... Resistin, leptin, plasminogen activator inhibitor-1 and retinol binding protein 4 induce insulin resistance in megakaryocytes. ... 2002) Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes ... Results Resistin, leptin, plasminogen activator inhibitor-1 and retinol binding protein 4 left platelets unchanged but induced ...http://www.haematologica.org/content/97/8/1149
Gentaur Molecular :Ray Biotech \ Rabbit Anti-Human Plasminogen Activator Inhibitor Type 1 \ 130-10011-200
Rabbit Anti-Human Plasminogen Activator Inhibitor Type 1 \ 130-10011-200 for more molecular products just contact us ... Rabbit Anti-Human Plasminogen Activator Inhibitor Type 1 storing antibdies for longer storage periods of the Rabbit Anti-Human ... Rabbit Anti-Human Plasminogen Activator Inhibitor Type 1 Human samples 80 % of the research is conducted on human samples. ... Rabbit Anti-Human Plasminogen Activator Inhibitor Type 1 antibody storage GENTAUR recommends for long therm storage to freeze ...http://www.antibody-antibodies.com/product_det.php?id=1782750&supplier=search&name=Rabbit%20Anti_Human%20Plasminogen%20Activator%20Inhibitor%20Type%201
The majority of type 1 plasminogen activator inhibitor associated with cultured human endothelial cells is located under the...
... human endothelial cells is located under the cells and is accessible to solution-phase tissue-type plasminogen activator.. R R ... human endothelial cells is located under the cells and is accessible to solution-phase tissue-type plasminogen activator. ... The interactions between exogenously added tissue-type plasminogen activator (t-PA) and the active form of type 1 plasminogen ... activator inhibitor (PAI-1) produced by and present in cultured human umbilical vein endothelial cells (HUVECs) were ...http://jcb.rupress.org/content/110/1/155
Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer...
Our data provide evidence for a hitherto unknown mechanism underlying the anti-invasive action of cannabidiol on human lung ... PURPOSE: Using human lung cancer cells, we evaluated the involvement of plasminogen activator inhibitor-1 (PAI-1) in the anti- ... 2015: Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung ... CBD research - Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human ...https://www.cbdepot.eu/cbd-research/decrease-of-plasminogen-activator-inhibitor-1-may-contribute-to-the-anti-in
KAKEN - Research Projects | Influences of extremely low-frequency alternate-current high magnetic fields on gene replication,...
Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human ... The efficiency of mutS-dependent mismatch repair with human cell extracts was also not affected by the magnetic field exposure ... Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human ... Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10837004/
Localization in tissues and secretion of eotaxin by cells from normal endometrium and endometriosis.
Next Document: Autocrine regulation of human preadipocyte migration by plasminogen activator inhibitor-1.. ... Humans. Immunohistochemistry. Interferon-gamma / pharmacology. Medroxyprogesterone / pharmacology. Progesterone Congeners / ... 0/CCL11 protein, human; 0/Chemokine CCL11; 0/Chemokines, CC; 0/Chemotactic Factors, Eosinophil; 0/Cytokines; 0/Progesterone ... Previous Document: Hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in the human hypothalamus are in.... ...http://www.biomedsearch.com/nih/Localization-in-tissues-secretion-eotaxin/10902814.html
Inflammation, a Link between Obesity and Cardiovascular Disease
In human vascular endothelial cells, leptin upregulates the expression of the plasminogen activator inhibitor-1 , and ... Leptin upregulates the expression of plasminogen activator inhibitor-1 in human vascular endothelial cells. Biochemical and ... It has also been found in the human lung, intestine, and heart  and is strongly expressed in the human ovaries and ... Chemerin has also been measured in a number of human inflammatory exudates, including ascitic fluids from human ovary cancer ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2929614/
Antioxidants and Endothelial Function: Therapeutic Implications | SpringerLink
1]. The endothelium actively regulates vascular tone, platelet aggregation, coagulation, fibrinolysis, and leukocyte activation ... Yamamoto K, Saito H (1998) A pathological role of increased expression of plasminogen activator inhibitor-1 in human or animal ... Browry VW, Mohr D, Clearly J, Stocker R (1995) Prevention of tocopherol-mediated peroxidation in ubiquinol-20-free human low ... The defence against free radicals protects endothelial cells from hyperglycemia-induced plasminogen activator inhibitor-1 over- ...https://link.springer.com/chapter/10.1007/978-1-4757-5551-0_10
Publications - Mayo Clinic
Leptin upregulates the expression of plasminogen activator inhibitor-1 in human vascular endothelial cells. Biochem Biophys Res ... Hoffmann M, Wolf J, Szyndler A, Singh P, Somers VK, Narkiewicz K. Serum of obstructive sleep apnea patients impairs human ... Human obesity is characterized by a selective potentiation of central chemoreflex sensitivity. Hypertension. 1999 May; 33(5): ... Somers VK, Conway J, Coats A, Isea J, Sleight P. Postexercise hypotension is not sustained in normal and hypertensive humans. ...http://www.mayo.edu/research/SearchPublications/Publications?authid=13434012
Table of Contents - March 01, 1993, 13 (3) | Arteriosclerosis, Thrombosis, and Vascular Biology
Plasminogen activator inhibitor activity in diabetic and nondiabetic survivors of myocardial infarction. R P Gray, D L ... A new anti-inflammatory leucine derivative, NPC-15669, inhibits growth of cultured human aortic smooth muscle cells. R L ... Increased synthesis of plasminogen activator inhibitor-1 by cultured human endothelial cells exposed to native and modified ... Tumor necrosis factor-alpha stimulates ICAM-1 expression in human vascular smooth muscle cells. T Couffinhal, C Duplàa, L Labat ...http://atvb.ahajournals.org/content/13/3
Eva Sverremark-Ekström -BIO-PROTOCOL
Stimulated in vivo synthesis of plasminogen activator inhibitor-1 in human adipose tissue. Thromb Haemost 108(3): 485-492. ... Epstein-Barr Virus (EBV) is a B-lymphotropic herpesvirus which the majority of adult human population is latently-infected with ... NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs. ... Pro-inflammatory and anti-inflammatory cytokines in human preterm and term cervical ripening. J Reprod Immunol 84(2): 176-185. ...https://bio-protocol.org/UserHome.aspx?id=1004181
arteriosclerosis | Arteriosclerosis, Thrombosis, and Vascular Biology
Plasminogen Activator Inhibitor-1) Expression Renders Alternatively Activated Human Macrophages Proteolytically Quiescent ... Abstract 562: Human Carotid Atherosclerosis Plaque Progression and Vessel Material Stiffness at Follow Up Had Positive ... Abstract 603: Induction of Dendritic Cell-Mediated Activation of T Cells From Atherosclerotic Plaques by Human Heat Shock ...http://atvb.ahajournals.org/keyword/arteriosclerosis
Complete Renin-Angiotensin-Aldosterone System (RAAS) Blockade in High-Risk Patients | Hypertension
Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. ... Table S1 lists the human studies of Aliskiren with ACEI/ARB with BP as an end point, and Table S3 lists studies of Aliskiren ... Structure-based design of aliskiren, a novel orally effective renin inhibitor. Biochem Biophys Res Commun. 2003;308:698-705. ... In this review, we provide a summary of the preclinical and clinical data that leads to the development of renin inhibitors and ...http://hyper.ahajournals.org/content/62/3/444
Brain-Targeted (Pro)renin Receptor Knockdown Attenuates Angiotensin II-Dependent Hypertension | Hypertension
Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. ... expressing both human renin and AGT transgenes were generated by breeding human renin mice with human angiotensinogen mice. RA ... Human renin and human angiotensinogen transgenic mice were generated at the University of Iowa Transgenic Animal Facilities (a ... The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human ...http://hyper.ahajournals.org/content/59/6/1188
KLK2 - Wikipedia
"Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1". Int. J. Cancer. 81 (3): 438-442 ... 2002). "Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) ... 1999). "Identification of a novel complex between human kallikrein 2 and protease inhibitor-6 in prostate cancer tissue". ... 1992). "Localization of human glandular kallikrein-1 gene to chromosome 19q13.3-13.4 by in situ hybridization". Hum. Hered. 41 ...https://en.wikipedia.org/wiki/KLK2
Pitavastatin-Induced Thrombomodulin Expression by Endothelial Cells Acts Via Inhibition of Small G Proteins of the Rho Family |...
10 expression of plasminogen activator inhibitor, and induce the secretion of tissue plasminogen activator.11,12⇓ Recently, it ... Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001; 344: 699-709. ... Bourcier T, Libby P. HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth ... 3 Activated protein C indirectly increases the fibrinolytic response by inhibiting plasminogen activator inhibitor. Recently, ...http://atvb.ahajournals.org/content/23/3/512
Human urokinase-PA Activity Kit Chromogenic (ab108915) | Abcam
Urokinase type Plasminogen Activator Human Chromogenic Activity Assay Kit (ab108915). Sensitivity , 6 mU/mL. Detect uPA in ... Plasminogen Activator Inhibitor-1) Expression Renders Alternatively Activated Human Macrophages Proteolytically Quiescent.. ... Urokinase type Plasminogen Activator Human Chromogenic Activity Assay Kit. See all Urokinase type Plasminogen Activator kits. ... Urokinase type plasminogen activator (uPA) is a highly restricted serine protease that converts the zymogen plasminogen to ...http://www.abcam.com/urokinase-type-plasminogen-activator-human-chromogenic-activity-assay-kit-ab108915.html
Simvastatin Reduces the Association of NMDA Receptors to Lipid Rafts | Stroke
Bourcier T, Libby P. HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth ... awaiting the studies in humans to confirm the benefit of treatment with statins or statins plus tissue plasminogen activator in ... Two different inhibitors of cholesterol synthesis, the inhibitor of Δ14-Δ7 reductase AY9944 and the inhibitor of HMGCoA ... effects of statin-enhanced thrombolytic therapy for stroke with recombinant human tissue-type plasminogen activator in the rat ...http://stroke.ahajournals.org/content/39/4/1269
Messenger RNA Determination of Estrogen Receptor, Progesterone Receptor, pS2, and Plasminogen Activator Inhibitor-1 by...
Inverse correlation between mRNA expression of plasminogen activator inhibitor-2 and lymph node metastasis in human breast ... Van Mourik J. A., Lawrence D. A., Loskutoff D. J. Purification of an inhibitor of plasminogen activator (antiactivator) ... Estrogen receptor (ER), progesterone receptor (PR), the estrogen-inducible protein pS2, and plasminogen activator inhibitor-1 ( ... Messenger RNA Determination of Estrogen Receptor, Progesterone Receptor, pS2, and Plasminogen Activator Inhibitor-1 by ...http://clincancerres.aacrjournals.org/content/5/6/1497
IJMS | Free Full-Text | Modeling Natural Anti-Inflammatory Compounds by Molecular Topology | HTML
Anisodamine counteracts lipopolysaccharide-induced tissue factor and plasminogen activator inhibitor-1 expression in human ... Juergens, U.R.; Stober, M.; Vetter, H. The anti-inflammatory activity of L-menthol compared to mint oil in human monocytes in ... 1. +. 5. ,. 666. ×. ATS. 7. m. -. 11. ,. 820. ×. ATS. 4. v. -. 9. ,. 178. ×. ATS. 7. v. +. 28. ,. 912. ×. ATS. 1. p. -. 42. ,. ... Matthews' coefficient is defined as shown in Equation (1):. M. C. C. =. (. T. P. ×. T. N. ). -. (. F. P. ×. F. N. ). (. T. N. + ...http://www.mdpi.com/1422-0067/12/12/9481/htm
Targeting Rho in Cardiovascular Disease | Circulation Research
Bourcier T, Libby P. HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth ... 6 and tissue-type plasminogen activator.7 Interestingly, in contrast to eNOS, in which Rho regulates gene expression by ... Activators of Rho include growth factors, cytokines, integrins, and G protein-coupled receptor ligands or hormones such as ... From a clinical perspective, large prospective trials with 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors or statins ...http://circres.ahajournals.org/content/87/7/526
α-Lipoic Acid Prevents Endothelial Dysfunction in Obese Rats via Activation of AMP-Activated Protein Kinase | Arteriosclerosis,...
... migration and plasminogen activator inhibitor 1 expression in human vascular smooth muscle cells. Diabetologia. 2005; 48: 1022- ... The effect of AMP-activated protein kinase and its activator AICAR on the metabolism of human umbilical vein endothelial cells ... Incubation of human aortic endothelial cells with ALA activated AMPK and protected cells from linoleic acid-induced apoptosis. ... Human aortic endothelial cells (HAECs) were obtained from BioWhittaker Inc. and maintained in the endothelial basal medium ( ...http://atvb.ahajournals.org/content/25/12/2488
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Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in ... The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. ... Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma. ... human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells. ...https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=22971619
C-Reactive Protein Attenuates Endothelial Progenitor Cell Survival, Differentiation, and Function | Circulation
Devaraj S, Xu DY, Jialal I. C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human ... rabbit anti-human VEGFR-2 (Alpha Diagnostics), mouse anti-human Tie-2 (Clone Ab33, Upstate Biotechnology), mouse anti-human ... with or without human vascular endothelial growth factor (VEGF)-A, human fibroblast growth factor-2, human epidermal growth ... Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell ...http://circ.ahajournals.org/content/109/17/2058.long