*  IFI6 - Wikipedia
1993). "Targeted breakage of a human chromosome mediated by cloned human telomeric DNA". Nat. Genet. 2 (4): 283-7. doi:10.1038/ ... Itzhaki JE, Porter AC (1991). "Targeted disruption of a human interferon-inducible gene detected by secretion of human growth ... Interferon alpha-inducible protein 6 is a protein that in humans is encoded by the IFI6 gene. This gene was first identified as ... 1986). "Characterization of a human gene inducible by alpha- and beta-interferons and its expression in mouse cells". EMBO J. 5 ...
  https://en.wikipedia.org/wiki/IFI6
*  Novel origins of copy number variation in the dog genome | Genome Biology | Full Text
Webber C, Ponting CP: Hotspots of mutation and breakage in dog and human chromosomes. Genome Res. 2005, 15: 1787-1797. 10.1101/ ... DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. Nature. 2006, 440: 1045-1049. 10.1038/ ... Chromosome-wise redistributions were done by repeatedly and randomly redistributing all features on the same chromosome to get ... Prior to analysis, all chromosomes were centered on their mean log2 ratio to remove potential chip biases. The × chromosome was ...
  https://genomebiology.biomedcentral.com/articles/10.1186/gb-2012-13-8-r73
*  Research
... and how these sequences cause genome instability and lead to human diseases.... ... Role of DNA secondary structures in fragile site breakage along human chromosome 10. Hum Mol Genet. 2013 Apr 1;22(7):1443-56. ... Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human ... and how these sequences cause genome instability and lead to human diseases. Human chromosomal fragile sites have been ...
  https://yhwanglab.wordpress.com/about-2/
*  Chromosomes - Humpath.com - Human pathology
Chromosomes. * diepoxybutane-induced chromosomal breakage 31 May 2006 Pathology Fanconi disease (Fanconi syndrome) See also ... acrocentric chromosome 17 October 2005 Definition: Chromosome whose centromere lies very near one end. See also metacentric ... metacentric chromosome 17 October 2005 Definition: Chromosome having its centromere in the middle. See also acrocentric ... 1996 - 2018 Humpath.com - Human pathology Site Map , Log in , Contact , RSS 2.0 ...
  http://humpath.com/spip.php?rubrique196&debut_articles=10
*  1 - Robert walters trading update
Renal Cell Carcinoma (RCC): This commonly involves translocation breakage points in human chromosome 3p, each representing a ... A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Hinge ... 1 Overview of the human spinal cord and the motorbiological function associated with each level. Oral viscous budesonide: a ... its genome therefore ranked high on the Human Genome Project's early "to do" list. CHAPTER 9 Robert walters trading update ...
  http://indonesiaforexonline.com/robert-walters-trading-update.html
*  Plus it
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal ... The study protocol was approved by the Committee on the Use of Human Subjects in Research at the Brigham and Women's Hospital, ... Kubota Y, Nash RA, Klungland A, Schar P, Barnes DE, Lindahl T. Reconstitution of DNA base excision-repair with purified human ... Jacob Selhub and Marie Nadeau at U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, ...
  http://cebp.aacrjournals.org/content/13/4/520
*  Plus it
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal ... leading to chromosome breaks in humans and hence increasing cancer risk (4). Alcohol may increase folate requirements in the ... McCann SE, Freudenheim JL, Marshall JR, Graham S. Risk of human ovarian cancer is related to dietary intake of selected ...
  http://cebp.aacrjournals.org/content/14/8/2056
*  Mouse Chromosome 18, Mammalian Genome | 10.1007/s003359901137 | DeepDyve
"Mouse Chromosome 18, Mammalian Genome" on DeepDyve, the largest online rental service for scholarly research with thousands of ... The lah conserved homology with three human chromosomes: 5, 10, and mice develop generalize hair loss associated with breakage ... Mouse Chromosome 18. Mouse Chromosome 18 Radice, Glenn L. 1999-10-01 00:00:00 Mammalian Genome 10, 959 (1999). Incorporating ... By generating cis-compound the human Aqp4 gene to human Chr 18q11-q12, which is more heterozygotes for mutations in the Apc and ...
  https://www.deepdyve.com/lp/springer_journal/mouse-chromosome-18-3eCoWV65qT
*  IJERPH | Free Full-Text | Antimony Toxicity | HTML
In addition antimony trioxide is possibly carcinogenic to humans. Improvements in working conditions have remarkably decreased ... The results of in vitro genotoxicity studies have shown positive results for chromosome breakage in human leukocytes [19]. In a ... Chromosome damage in human cell cultures induced by metal salts. Mutat. Res 1972, 16, 332-336. [Google Scholar] ... Cardiovascular effects in humans are supported by the finding of cardiac effects following parenteral administration of ...
  https://www.mdpi.com/1660-4601/7/12/4267/htm
*  Midterm 2 Flashcards by MONICA RUIZ-SOSA | Brainscape
Occurs when a single chromosome undergoes breakage and rearrangement within itself.. • The most common inversion seen in humans ... Humans typically have 46 chromosomes (23 pairs) with 44 autosomes (22 pairs) and 2 sex chromosomes (1 pair). ... X chromosome is much larger than Y chromosome.. • In 46:XX females, one X chromosome is shut down in 10-49% of her diploid ... Each human somatic cells contains two copies of the entire human genome. -human diploid genome contains about 6.3 billion base ...
  https://www.brainscape.com/flashcards/midterm-2-5869968/packs/8768525
*  L-methylfolate, Methylcobalamin, and N-acetylcysteine in the Treatment of Alzheimer's Disease-Related Cognitive Decline «...
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal ... Hypomethylation induces gene transcription and DNA strand breakage.78,79 In cultured neurones, Hcy itself induces breakages,80 ... Fenech M. The role of folic acid and vitamin B12 in genomic stability of human cells. Mutat Res. 2001;475:57-67.. 80. Kruman II ... Kim J, Hannibal L, Gherasim C, Jacobsen DW, Banerjee R. A human B12 trafficking protein uses glutathione transferase activity ...
  http://primarypsychiatry.com/l-methylfolate-methylcobalamin-and-n-acetylcysteine-in-the-treatment-of-alzheimeras-diseasearelated-cognitive-decline/
*  Nijmegen breakage syndrome - Wikipedia
NBS is caused by a mutation in the NBS1 gene, located at human chromosome 8q21. The disease is inherited in an autosomal ... Nijmegen breakage syndrome (NBS), also known as Berlin breakage syndrome, ataxia telangiectasia variant 1 (AT-V1) and Seemanova ... "Nijmegen breakage syndrome. The International Nijmegen Breakage Syndrome Study Group". Arch Dis Child. 82 (5): 400-6. 2000. doi ... Group, The International Nijmegen Breakage Syndrome Study (2000-05-01). "Nijmegen breakage syndrome". Archives of Disease in ...
  https://en.wikipedia.org/wiki/Nijmegen_breakage_syndrome
*  KAKEN - Research Projects | Effects of radiation and chemicals on human sperm chromosomes (KAKENHI-PROJECT-02455006)
The incidence of breakage-type aderations was far higher than that of exchange- type aberrations. The dose-dependent increase ... Publications] Kamiguchi,Y.et al: 'Chemical (antineoplastic agents)-induced chromosome damage in human spermatozoa.' Jpn.J.Human ... induced chromosome damage in human spermatozoa.' Japanese Journal of Human Genetics. 38. (1993). *. Description. 「研究成果報告書概要(和文 ... Publications] Kamiguchi,Y.et al: 'Human sperm chromosome analysis as a mutagenicity test of chemicals.' Mutation Res.. *. ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02455006/
*  Plus it
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal ... The approximate determination of spermine in single human organs. Biochem J 1933;27:1152-6. ... in vitro induces uracil misincorporation and DNA hypomethylation and inhibits DNA excision repair in immortalized normal human ...
  http://cancerpreventionresearch.aacrjournals.org/content/4/11/1825
*  Bloom's syndrome chromosomes - Stock Image C003/0949 - Science Photo Library
The dark areas show an increase in chromosome breakage and rearrangement. This rare genetic disorder, also known as congenital ... Light micrograph of human chromosomes from a lymphocyte blood cell in a patient with Bloom's syndrome, showing sister chromatid ... chromosome breakage, condition, congenital telangiectatic erythema, diagnosis, disease, genetics, healthcare, human chromosomes ... Caption: Light micrograph of human chromosomes from a lymphocyte blood cell in a patient with Bloom's syndrome, showing sister ...
  http://www.sciencephoto.com/media/95182/view
*  Bloom's syndrome chromosomes - Stock Image C003/0948 - Science Photo Library
The dark areas show an increase in chromosome breakage and rearrangement. This rare genetic disorder, also known as congenital ... Coloured light micrograph of human chromosomes from a lymphocyte blood cell in a patient with Bloom's syndrome, showing sister ... Caption: Coloured light micrograph of human chromosomes from a lymphocyte blood cell in a patient with Bloom's syndrome, ... Keywords: bloom, bloom'ss syndrome, chromosomal abnormality, chromosome breakage, colour, coloured, condition, congenital ...
  http://www.sciencephoto.com/media/95181/view
*  Non-Hodgkin's lymphoma among electric utility workers in Ontario: the evaluation of alternate indices of exposure to 60 Hz...
1986) Effect of low-level, 60-Hz electromagnetic fields on human lymphoid cells: I. Mitotic rate and chromosome breakage in ... 1987) Interaction of extremely low frequency electric and magnetic fields with humans. Health Phys 53:585-606. ... 1986) The effect of low-level 60-Hz electromagnetic fields on human lymphoid cells. II. Sister-chromatid exchanges in ... 1986) Transferrin binding to two human colon carcinoma cell lines: characterization and effect of 60-Hz electromagnetic fields. ...
  http://oem.bmj.com/content/57/4/249
*  Longevity Report 91
25a] Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and ... Telomeres are repeating sequences of DNA at the end of chromosomes. In humans, but not all animals, as cells divide their ... Trials on humans with 200ug/d for just 5 years halved the cancer mortality and reduced over-all mortality15. Other human ... First, extrapolating dosage from rodents to humans by body weight overestimates the human requirement, leading, sometimes, to ...
  http://www.quantium.plus.com/lr/lr91.htm
*  Patent US5599664 - Method for characterizing polymer molecules or the like - Google Patents
Breakage of large polymer molecules mounted on a microscope slide is prevented by condensing the molecules before mounting and ... A typical human chromosome may contain a single DNA molecule stretching inches in length. Nature provides a clever packaging ... Breakage of large polymer molecules mounted on a microscope slide is prevented by condensing the molecules before mounting and ... as is a human chromosome. Since it is possible to view several molecules in a sample simultaneously, it is also possible to ...
  http://www.google.ca/patents/US5599664
*  Nutritional Factors in Human Cancers | SpringerLink
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal ... Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer. Proc Natl Acad Sci USA. ... Sutherland G.R. The role of nucleotides in human fragile site expression. Mutat Res. 1988; 200: 207-213.PubMedCrossRefGoogle ... Isley W.L., Underwood L.E., and Clemmons D.R. Dietary components that regulate serum somatomedin-C concentrations in humans. J ...
  https://link.springer.com/chapter/10.1007/978-1-4757-3230-6_3
*  Supplements and Tuning Up Metabolism1-3 - Redorbit
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal ... Folate deficiency breaks chromosomes due to massive incorporation of uracil in human DNA (millions per cell) (8), with ... The effect of folie acid deficiency and MTHFR C677T polymorphism on chromosome damage in human lymphocytes in vitro. Cancer ... For most of human evolution, dietary energy shortage was likely to have limited population growth, and, because food was dilute ...
  http://www.redorbit.com/news/health/106408/supplements_and_tuning_up_metabolism13/
*  Chromosome 22 (human) - Wikipedia
... a circular structure called ring chromosome 22 that is caused by the breakage and reattachment of both ends of the chromosome. ... Chromosome 22 is one of the 23 pairs of chromosomes in human cells. Humans normally have two copies of chromosome 22 in each ... Chromosome 22 was the first human chromosome to be fully sequenced. Chromosome 22 was originally identified as the smallest ... Chromosome 22 is the second smallest human chromosome (chromosome 21 being smaller), spanning about 49 million DNA base pairs ...
  https://en.wikipedia.org/wiki/Chromosome_22_(human)
*  The Influence of Folate and Multivitamin Use on the Familial Risk of Colon Cancer in Women | Cancer Epidemiology, Biomarkers &...
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal ... Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer. Proc. Natl. Acad. Sci. USA ... Blount et al. (51) demonstrated that folate deficiency was related to massive misincorporation of uracil into human DNA and ... Feinberg A. P., Gehrke C. W., Kuo K. C., Ehrlich M. Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer ...
  http://cebp.aacrjournals.org/content/11/3/227.full
*  SMC6 - Wikipedia
In humans, a chromosome breakage syndrome characterized by severe lung disease in early childhood is associated with a mutation ... Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene. It is involved in the ... 2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724-31. doi:10.1038/ ... "Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease". J. Clin. Invest. 126 (8): 2881-92 ...
  https://en.wikipedia.org/wiki/SMC6
*  SMC5 - Wikipedia
In humans, a chromosome breakage syndrome characterized by severe lung disease in early childhood is associated with a mutation ... Structural maintenance of chromosomes protein 5 is a protein encoded by the SMC5 gene in human. It is involved in the ... 2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369-74. doi:10.1038/nature02465. PMC 2734081 . ... "Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease". J. Clin. Invest. 126 (8): 2881-92 ...
  https://en.wikipedia.org/wiki/SMC5