*  OEC - Selected Issues in Depth - Human Genetic Therapies and Human Enhancement
The Human Genome Project ended in 2003. Not only did this undertaking provide valuable insight into complex human diseases, but ... THE ETHICS OF HUMAN ENHANCEMENT Dr Nierman's work helps us to see both what's currently available in terms of genomic therapies ... based on the genetic profile of individuals: Dr Mendelsohn, who works in Personalized Cancer Therapy at the MD Anderson ... Human genome sequencing has an important role to play in the diagnosis of disease. As suggested in the previous clip, new ...
  http://www.onlineethics.org/Resources/30931/31015/31239.aspx
*  Shire Human Genetic Therapies, Inc - Patent applications
Shire Human Genetic Therapies, Inc. Shire Human Genetic Therapies, Inc Patent applications. ... GENE THERAPY FOR SULFATASE DEFICIENCY - This invention relates to methods and compositions for the diagnosis and treatment of ... Crystal structure of human alpha-n-acetylglucosaminidase - The present invention provides the three-dimensional structure of ... Crystal structure of human alpha-N-acetylglucosaminidase - The present invention provides the three-dimensional structure of ...
  http://www.patentsencyclopedia.com/assignee/shire-human-genetic-therapies-inc/
*  Shire Appoints Sylvie Gregoire President of Human Genetic Therapie... ( Seasoned leader brings added ex...)
24First...In her role as President of Shire Human Genetic Therapies and a member... Sylvie brings an impressive level of ... knowledge and expertise to Shire...,Shire,Appoints,Sylvie,Gregoire,President,of,Human,Genetic,Therapies,Business,biological, ... 24First...In her role as President of Shire Human Genetic Therapies and a member... Sylvie brings an impressive level of ... In her role as President of Shire Human Genetic Therapies and a member of Shire's Management Committee, Sylvie is responsible ...
  http://www.bio-medicine.org/biology-technology-1/Shire-Appoints-Sylvie-Gregoire-President-of-Human-Genetic-Therapies-Business-781-1/
*  Gene therapy Genetic Disorders,Genetic testing and counseling Genetic Disorders,Genetics education Genetic Disorders,Human...
Website related to Gene therapy Genetic Disorders,Genetic testing and counseling Genetic Disorders,Genetics education Genetic ... The IMMD is a genetic testing laboratory located in Germany. Provides genetic tests for hereditary breast cancer, various ... Genetic Disorders: The Links to Diet http://www.ctds.info. Explores the role of diet in birth defects and genetic disorders. ... A critical effort to provide public and professional education for many of the identified Jewish genetic disorders. Find info ...
  http://medicalhealthsites.com/Genetic_Disorders/page-1.html?s=A
*  Genetic Therapy Reverses Nervous System Damage in Animal Model of Inherited Human Disease
... 10.03.2005 ... "As we move toward the clinical use of this therapy in humans, we must develop and utilize non-invasive methods to monitor the ... one of the first steps that will prepare this particular gene therapy for practical use in humans. The gene is transported via ... If this approach can be successfully applied to humans, say the researchers, it might one day treat an entire class of diseases ...
  http://www.innovations-report.com/html/reports/life-sciences/report-41585.html
*  Human Genetics: Articles On Basic Genetics, Traits, Disorders, Gene Therapy & Genetic Engineering and Ethics
... the increasing role of gene therapy and the benefits and ethics of genetic engineering. ... The human genetics channel at Bright Hub provides articles with information on research and theories about the fascinating ... Types of Human Genetic Disorders. Genetic disorders are diseases or conditions that are caused by abnormalities in genes or ... Gene Therapy: How Gene Therapy Could Cure Brain Tumors. Gene therapy methods have had an 80% success rate in treating lab rats ...
  http://www.brighthub.com/science/genetics.aspx
*  ChemE | News | Student News & Events
Shire Human Genetic Therapies, Inc.: Summer internship opportunities are available. [Details] Life Sciences Internship ...
  http://web.mit.edu/cheme/news/student-news-spring09/index-march30.html
*  Patent US5981501 - Methods for encapsulating plasmids in lipid bilayers - Google Patents
Shire Human Genetic Therapies, Inc.. Pulmonary delivery of mRNA. US9629804. Oct 22, 2014. Apr 25, 2017. Shire Human Genetic ... Shire Human Genetic Therapies, Inc.. MRNA therapy for Fabry disease. US9340786. Mar 24, 2011. May 17, 2016. Rxi Pharmaceuticals ... Shire Human Genetic Therapies, Inc.. MRNA therapy for phenylketonuria. US9597413. Jun 18, 2014. Mar 21, 2017. ... Shire Human Genetic Therapies, Inc.. CFTR mRNA compositions and related methods and uses. ...
  http://www.google.com/patents/US5981501?dq=3691140
*  Patent US4401796 - Solid-phase synthesis of polynucleotides - Google Patents
Shire Human Genetic Therapies, Inc.. Mrna therapy for phenylketonuria. WO2015061500A1. Oct 22, 2014. Apr 30, 2015. Shire Human ... Shire Human Genetic Therapies, Inc.. Encapsulation of messenger rna. WO2016090262A1. Dec 4, 2015. Jun 9, 2016. Shire Human ... Shire Human Genetic Therapies, Inc.. Methods for purification of messenger rna. WO2015061461A1. Oct 22, 2014. Apr 30, 2015. ... Shire Human Genetic Therapies, Inc.. Methods and compositions for delivering mrna coded antibodies. ...
  http://www.google.com/patents/US4401796
*  Patent US5959083 - Tetravalent bispecific receptors, the preparation and use thereof - Google Patents
Shire Human Genetic Therapies, Inc.. Anti-ccl2 and anti-loxl2 combination therapy for treatment of scleroderma. ... Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell. ... Bispecific antibodies against human TWEAK and human IL17 and uses thereof. US9765153. Dec 19, 2014. Sep 19, 2017. Hoffmann-La ... Bispecific antibodies against human tweak and human il17 and uses thereof. WO2014006124A1. Jul 4, 2013. Jan 9, 2014. F. ...
  http://www.google.com/patents/US5959083
*  Search of: Fabry Disease - List Results - ClinicalTrials.gov
Shire Human Genetic Therapies, Inc.. Other / Industry. *Observational Model: Cohort. *Time Perspective: Prospective ... Study to Compare the Efficacy and Safety of Oral AT1001 and Enzyme Replacement Therapy in Patients With Fabry Disease. *Fabry ... An Open-Label Maintenance Study of the Enzyme Replacement Therapy Replagal in Patients With Fabry Disease. *Fabry Disease ... Drug: Moss-aGal (recombinant human alpha-galactosidase A produced in moss). Interventional. Phase 1. *Greenovation Biotech GmbH ...
  https://clinicaltrials.gov/ct2/results?term=Fabry%20Disease
*  An Observational Study Evaluating Anti-Idursulfase Serum Antibody Response in Hunter Syndrome Patients - Full Text View -...
Patients will not be provided idursulfase by Shire Human Genetic Therapies, Inc. or the HOS. ... Genetic Diseases, X-Linked. Genetic Diseases, Inborn. Heredodegenerative Disorders, Nervous System. Mucopolysaccharidoses. ... mps ii therapy. MPS II treatment. iduronate 2 sulfatase. hunter syndrome treatment. hunter's syndrome treatment. hunter ... syndrome therapy. hunter's disease treatment. MPSII. mucopolysaccharides. lysosomal storage disease. lysosomal storage disorder ...
  https://clinicaltrials.gov/ct2/show/NCT00882921?cond=%22Hunter+syndrome%22&rank=6
*  Treatment Protocol of Velaglucerase Alfa for Patients With Type 1 Gaucher Disease - Full Text View - ClinicalTrials.gov
Shire Human Genetic Therapies, Inc.. More Information. Go to Study Description Study Design Interventions Eligibility Criteria ... Velaglucerase alfa (Gene-Activated™ human glucocerebrosidase;GA-GCB) is produced in a continuous human cell line using ... Enzyme Replacement Therapy. Gaucher disease. glucocerebrosidase. beta-glucocerebrosidase. Acid beta-glucocerebrosidase. ... Genetic and Rare Diseases Information Center resources: Gaucher Disease Gaucher Disease Type 1 Sphingolipidosis ...
  https://clinicaltrials.gov/ct2/show/NCT00954460?term=GBA&rank=9
*  Safety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase Therapy - Full Text...
Shire Human Genetic Therapies, Inc.. Principal Investigator:. Roberto Giugliani, MD, PhD. Hospital de Clinicas de Porto Alegre ... enzyme replacement therapy. hunter syndrome treatment. hunter's syndrome treatment. hunter syndrome therapy. hunter's disease ... Safety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase Therapy. The safety ... mps ii therapy. MPS II treatment. ert treatment. elaprase. idursulfase. iduronate sulfatase. iduronate 2 sulfatase. ...
  https://clinicaltrials.gov/show/NCT00607386
*  Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase - Full Text...
Shire Human Genetic Therapies, Inc.. Principal Investigator:. Anna Tylki-Szmanska, M.D.. Children's Memorial Health Institute, ... A Multicenter Open-Label Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Patients With ... Gene-Activated® human glucocerebrosidase (GA-GCB; velaglucerase alfa) is produced in a continuous human cell line using ... Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase. The safety ...
  https://clinicaltrials.gov/ct2/show/NCT00478647?term=%22Children
*  Patente US5744335 - Process of transfecting a cell with a polynucleotide mixed with an ... - Google Patentes
Shire Human Genetic Therapies, Inc.. Cleavable lipids. WO2012170930A1. 8 Jun 2012. 13 Dic 2012. Shire Human Genetic Therapies, ... Shire Human Genetic Therapies, Inc.. Pulmonary delivery of mRNA. US9629804. 22 Oct 2014. 25 Abr 2017. Shire Human Genetic ... Shire Human Genetic Therapies, Inc.. Mrna therapy for phenylketonuria. WO2015061500A1. 22 Oct 2014. 30 Abr 2015. Shire Human ... mRNA for use in treatment of human genetic diseases. US9061021. 8 Jul 2014. 23 Jun 2015. Shire Human Genetic Therapies, Inc.. ...
  http://www.google.es/patents/US5744335?dq=flatulence
*  Patent US6345260 - Scheduling interface system and method for medical professionals - Google Patents
Shire Human Genetic Therapies, Inc.. Systems and methods for managing treatment of an orphan disease. ... System and method for real-time scheduling of human and non-human resources. ... Therapy adherence methods and architecture. US8234128. 30 Dec 2003. 31 Jul 2012. Baxter International, Inc.. System and method ... System and method for remote monitoring and/or management of infusion therapies. ...
  https://www.google.com.au/patents/US6345260
*  Patente US3096560 - Process for synthetic vascular implants - Google Patentes
Shire Human Genetic Therapies, Inc.. Pulmonary delivery of mRNA. US9629804. 22 Oct 2014. 25 Abr 2017. Shire Human Genetic ... Shire Human Genetic Therapies, Inc.. MRNA therapy for phenylketonuria. US9549835. 18 Ago 2014. 24 Ene 2017. Endologix, Inc.. ... Shire Human Genetic Therapies, Inc.. MRNA therapy for Fabry disease. US9315472. 1 May 2014. 19 Abr 2016. Massachusetts ... Shire Human Genetic Therapies, Inc.. CFTR mRNA compositions and related methods and uses. ...
  http://www.google.es/patents/US3096560
*  Treatment Protocol of Velaglucerase Alfa for Patients With Type 1 Gaucher Disease - Full Text View - ClinicalTrials.gov
Shire Human Genetic Therapies, Inc.. More Information Publications automatically indexed to this study by ClinicalTrials.gov ... Velaglucerase alfa (Gene-Activated™ human glucocerebrosidase;GA-GCB) is produced in a continuous human cell line using ... Genetic and Rare Diseases Information Center resources: Gaucher Disease Gaucher Disease Type 1 Sphingolipidosis ... Genetic Diseases, Inborn. Lipidoses. Lipid Metabolism, Inborn Errors. Lysosomal Storage Diseases. Metabolic Diseases. Lipid ...
  https://clinicaltrials.gov/ct2/show/NCT00954460?cond=%22Gaucher+disease+type+1%22&rank=8
*  Search of: 'Gaucher Disease' [DISEASE] - List Results - ClinicalTrials.gov
Shire Human Genetic Therapies, Inc.. Industry. *Allocation: Non-Randomized. *Intervention Model: Single Group Assignment ... A Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Gaucher Disease. *Gaucher Disease, ... Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) ERT Compared With Imiglucerase in Type I Gaucher Disease. *Gaucher ... Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase. *Gaucher ...
  https://clinicaltrials.gov/ct2/results?term=%22Gaucher+Disease%22+%5BDISEASE%5D
*  Vpriv - FDA prescribing information, side effects and uses
Shire Human Genetic Therapies, Inc.. 300 Shire Way. Lexington, MA 02421. Vpriv is a registered trademark of Shire Human Genetic ... the recommended human daily dose. Because animal reproduction studies are not always predictive of human response, Vpriv should ... Imiglucerase therapy was stopped, and treatment with Vpriv was administered every other week at the same number of units as the ... Patients were not allowed to have had disease-specific therapy for at least the previous 30 months; all but one had no prior ...
  https://www.drugs.com/pro/vpriv.html
*  An Open-Label Extension Study of GA-GCB ERT in Patients With Type 1 Gaucher Disease - Full Text View - ClinicalTrials.gov
Shire Human Genetic Therapies, Inc.. More Information Publications automatically indexed to this study by ClinicalTrials.gov ... An Open-Label Extension Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Patients With ... Gene-Activated® human glucocerebrosidase (GA-GCB,velaglucerase alfa) is produced in a continuous human cell line using ... Enzyme Replacement Therapy. Gaucher disease. glucocerebrosidase. beta-glucocerebrosidase. Acid beta-glucocerebrosidase. ...
  https://clinicaltrials.gov/ct2/show/NCT00635427?term=GBA&rank=10
*  Patente US6055454 - Cardiac pacemaker with automatic response optimization of a physiologic ... - Google Patentes
Shire Human Genetic Therapies, Inc.. MRNA therapy for Fabry disease. US9308375. 5 Sep 2014. 12 Abr 2016. Cardiac Pacemakers, ... Shire Human Genetic Therapies, Inc.. MRNA therapy for phenylketonuria. US9526909. 26 Ago 2015. 27 Dic 2016. Cardiac Pacemakers ... Shire Human Genetic Therapies, Inc.. Pulmonary delivery of mRNA. US9623252. 18 Ago 2016. 18 Abr 2017. Cardiac Pacemakers, Inc. ... Shire Human Genetic Therapies, Inc.. CFTR mRNA compositions and related methods and uses. ...
  http://www.google.es/patents/US6055454
*  Safety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase Therapy - Full Text...
Shire Human Genetic Therapies, Inc.. Principal Investigator:. Roberto Giugliani, MD, PhD. Hospital de Clinicas de Porto Alegre ... enzyme replacement therapy. hunter syndrome treatment. hunter's syndrome treatment. hunter syndrome therapy. hunter's disease ... mps ii therapy. MPS II treatment. ert treatment. elaprase. idursulfase. iduronate sulfatase. iduronate 2 sulfatase. ... Genetic Diseases, Inborn. Lysosomal Storage Diseases. Mucinoses. Connective Tissue Diseases. Metabolic Diseases. Mental ...
  https://clinicaltrials.gov/ct2/show/NCT00607386?term=SIDS&rank=15