Editorial Board ::: Current HIV Research
Zhao's research interest is to study virus-host interactions, viral pathogenicity and drug resistance as well as antiviral drug ... Zhao's research interest is to study virus-host interactions, viral pathogenicity and drug resistance as well as antiviral drug ... He is the member of the WHO's vaccine and drug resistance advisory committees and the fellow of the American Academy of ... Rice's research interest, from this PhD studies to the present, has been the study viral-host interactions. Dr. Rice has over ...https://benthamscience.com/journals/current-hiv-research/editorial-board/
The Puzzle of HIV Neutral and Selective Evolution, Molecular Biology and Evolution | 10.1093/molbev/msy089 | DeepDyve
Pre-existence and emergence of drug resistance in a generalized model of intra-host viral dynamics . Epidemics 4 ( 4 ): 187 - ... Pre-existence and emergence of drug resistance in a generalized model of intra-host viral dynamics . Epidemics 4 ( 4 ): 187 - ... 1997 . Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations . J Theor Biol. 184 ( 2 ... 1997 . Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations . J Theor Biol. 184 ( 2 ...https://www.deepdyve.com/lp/ou_press/the-puzzle-of-hiv-neutral-and-selective-evolution-acrFWvodHg
Infection and Drug Resistance | Volume 8 - Dove Press Open Access Publisher
... fungal and viral) and the development and institution of preventative strategies to minimize the development and spread of ... Influence of host resistance on viral adaptation: hepatitis C virus as a case study Plauzolles A, Lucas M, Gaudieri S ... Prevalence and resistance pattern of Moraxella catarrhalis in community-acquired lower respiratory tract infections Shaikh SBU ... Laboratory-based nationwide surveillance of antimicrobial resistance in Ghana Opintan JA, Newman MJ, Arhin RE, Donkor ES, ...https://www.dovepress.com/infection-and-drug-resistance-i1024-j28
NIDA International: What's New: NIDA and French Research Agency Host Satellite at AIDS 2014, Announce New Fellows in HIV and...
... which focused on drug use, HIV, and hepatitis C (HCV). NIDA grantee Don C. Des Jarlais, Ph.D., Mount Sinai Beth Israel, ... presented a global overview on the general context of research on HIV/HCV infection and drug use. ... including genital viral load decay, transmitted drug resistance, and host inflammatory markers. Her mentor is Ann C. Duerr, M.D ... Trupti Ishwar Gilada, M.D., India, who will study the effect of alcohol and substance abuse disorders on viral and host events ...https://www.drugabuse.gov/international/whats-new-nida-french-research-agency-host-satellite-aids-2014-announce-new-fellows-in-hiv-drug-use
Drug aimed at 2 bioterror agents blocks live viral infection, Weill Cornell te... ( NEW YORK (Dec. 19 2007) -- Two deadl...)
Drug,aimed,at,2,bioterror,agents,blocks,live,viral,infection,,Weill,Cornell,team,reports,biological,biology news articles, ... Feline virus, antiviral drug studied to understand drug resistance. 9. Cornell will host the Northeast Biofuel Summit, Nov. 11- ... Drug aimed at 2 bioterror agents blocks live viral infection, Weill Cornell team reports ... The mode of transmission isn't clear, but is thought to be relatively easy -- either by close contact with an infected host or ...http://www.bio-medicine.org/biology-news-1/Drug-aimed-at-2-bioterror-agents-blocks-live-viral-infection--Weill-Cornell-team-reports-1676-1/
Microbiology and Infection PhD/MSc by Research - Postgraduate degree study - University of Birmingham
... host-pathogen interactions, pathogen transmission and drug resistance. ... We work with a range of bacterial and viral pathogens and study mechanisms of pathogenesis, ... A primary focus of research within IMI is combatting the global threat of antimicrobial resistance (AMR). By taking a multi- ... in the world we are at the vanguard of innovative research into combatting antimicrobial and antibiotic resistance. We do this ...https://www.birmingham.ac.uk/postgraduate/courses/research/med/microbiology-infection.aspx
Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of...
Reorganization of the host epigenome by a viral oncogene. Genome Res. 2012;22(7):1212-21. doi:10.1101/gr.132308.111.View ... the role of epigenetics in drug resistance is less well understood. To investigate mechanisms of drug resistance, we performed ... Panasci L, Xu ZY, Bello V, Aloyz R. The role of DNA repair in nitrogen mustard drug resistance. Anticancer Drugs. 2002;13(3): ... Epigenetic mechanisms in tumorigenesis, tumor cell heterogeneity and drug resistance. Drug Resist Updat. 2012;15(1-2):21-38. ...https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-016-0305-0
Common Flu Drugs Meet Growing Resistance | Medpage Today
... the proportion of influenza A strains worldwide that are resistant to the common antiflu drugs amantadine and rimantadine has ... which prevents fusion of the viral and host-cell membranes, and stops release of viral RNA into the cytoplasm, thereby ... "We were alarmed to find such a dramatic increase in drug resistance in circulating human influenza viruses in recent years," ... 21-About 12% of influenza A strains worldwide have developed resistance to the most commonly used antiflu drugs, including ...https://www.medpagetoday.com/infectiousdisease/uritheflu/1781
Palm Project Interviews: A Talk With Steven Deeks | Treatment Action Group
But in the past few years, it's become quite clear to us that we really can't fully understand how drug resistance and viral ... In the last ten years, I've focused in on trying to understand the pathogenesis of drug resistance; focusing on the virus host ... And so while we're all still focusing on drug resistance and viral fitness, we're devoting more and more time to characterizing ... fairly potent drug; and it's going have a huge impact on my patients with drug resistance. So I figured we would talk for a ...http://www.treatmentactiongroup.org/tagline/2008/winter/palm-project-interviews-talk-steven-deeks
"Human immunodeficiency virus type 1 pharmacogenomics in clinical pract" by Roberto Patarca, Alejandro Isava et al.
... because control of infection and its consequences is limited by the development of viral drug resistance and by host factors. ... The only Food and Drug Administration-approved kit for HIV drug resistance testing by genotypic sequencing is commercially ... This report summarizes studies published to date on the significance of testing of HIV-1 resistance to antiretroviral drugs. ... Not only has the paradigm of viral pharmacogenomics in the form of HIV genotypic sequencing been useful in treating other viral ...http://nsuworks.nova.edu/hpd_com_faculty_articles/205/
Editors for Microbiology and Infectious Disease | About | eLife
viral-host interactions. retroviral restriction factors. HIV drug resistance. * Dominique Soldati-Favre. University of Geneva, ... host-microbiota interactions. microbiome. mucosal immunology. Competing interests statement. Wendy Garrett receives funding ... Her work explores host-microbiota interactions underlying mucosal immune homeostasis, gastrointestinal inflammatory disorders, ... Li's research interest has been focusing on the molecular mechanisms of viral infections: currently his laboratory combines ...https://elifesciences.org/about/people/microbiology-infectious-disease
Functional Genetics Announces Two Separate Awards from the National Institute of Allergy and Infectious Diseases to Develop...
Functional Genetics' approach of host-based targeting of viral disease is designed to overcome issues that have previously ... including acquired drug resistance and the relatively narrow spectrum of current therapies.. About Functional Genetics, Inc. ... This grant from NIAID validates our mission of developing host-directed monoclonal antibodies with application to a broad- ... These programs will initiate the development of monoclonal antibodies that target two different host molecules, Nedd4 and Robo1 ...https://www.pr.com/press-release/244777
Cracking 'Enigma code' of common cold - Biology, The University of York
Anti-viral drugs. The team is now working to screen for potential anti-viral drugs that target this decoding mechanism. ... "This new research means that treatment would be less likely to trigger drug resistance, which is currently one of the major ... problems in anti-viral therapy. This discovery could be a great leap forward in curing a host of conditions." ... We now need a drug that has the same effect as pouring sand into the watch; every part of the viral mechanism could be disabled ...https://www.york.ac.uk/biology/news-events/news/crackingenigmacodeofcommoncold/
ABSTRACT INDEX* : JAIDS Journal of Acquired Immune Deficiency Syndromes
172 Monitoring HIV Drug Resistance as a Guide to Understanding Viral Pathogenesis Wainberg, Mark - McGill University ... 216 Self-Renewing Monocytoid Cells (SRMC) Derived from Cultured Blood Monocytes as Targets and Hosts for Viruses Popovic, ... 197 Population Level Drug Resistance in HIV Type 1 Protease and Reverse Transcriptase in Cameroon: 1995-2010 Review Torimiro, ... 119 Viral Attack and Cellular Defense: The Role of Cellular Restrictions in the Biology of Primate Lentiviruses Stevenson, ...https://journals.lww.com/jaids/Fulltext/2011/04002/ABSTRACT_INDEX_.4.aspx
MIT Microbiology Program :: Graduate Program
Special emphasis on specific viral, bacterial, and eukaryotic microorganisms and their interaction with animal hosts with focus ... antimicrobial drug resistance, and toxicology.. E. Alm, J. Runstadler. Biomolecular Kinetics and Cellular Dynamics -20.420J( ... pathogens and the human or animal host. Special focus is given to current research on microbe/host interactions, infection of ... Focuses on the principles of host-pathogen interactions with an emphasis on infectious diseases of humans. Presents key ...http://web.mit.edu/microbiology/grad.html
Pro sql server 2005 replication ebook free download - Hosting Blog
2008) proposed that targeting of HDFs essential for the viral cycle but not critical for the host may avoid drug resistance due ... It is the WordPress-specific hosting service that hosts only WordPress based websites. Get the best web hosting in Chennai by ... We believe each host that appears on our site provides a great service at a good price. Our web hosting pro sql server 2005 ... Then, select the files to be uploaded and drag-and-drop web hosting no advertising under the www folder. The findings and ...http://thecapitalbkc.com/sql-server-2005/pro-sql-server-2005-replication-ebook-free-download.html
How to install ftp server on centos 5.5 - Hosting Blog
2008) proposed that targeting of HDFs essential for the viral cycle but not critical for the host may avoid drug resistance due ... VPS hosting works the same as Shared Hosting, except you have additional features such as your own WHM panel. Besides, ... Downtown Host guarantee a minimum of 99. RNA expression overview shows RNA-data from three different sources: Internally ... GoDaddy is a feature-packed web hosting service that boasts rock-solid uptime, excellent customer service, and flexible website ...http://multivac.info/how-server/how-to-install-ftp-server-on-centos-55.html
HIV Host Response - QIAGEN
Many of these novel genes involved in the viral life cycle were used as drug targets, some of which are on the market today. On ... high mutation rate further complicates treatment and eradication due to the rapid development of drug resistance. Since its ... Many of these novel genes involved in the viral life cycle were used as drug targets, some of which are on the market today. On ... HIV Host Response RT2 Profiler PCR Array The Human HIV Host Response RT² Profiler PCR Array profiles the expression of 84 genes ...https://www.qiagen.com/mx/shop/genes-and-pathways/complete-biology-list/hiv-host-response/
Pace University - BIO - Biology
... drug resistance, and immunity. Viral as well as bacterial pathogens are discussed.. Course Rotation: Spring. ... Other topics include chemotherapy, host-parasite relationships, and the basis of the immune process. Laboratory includes ... Mechanisms of drug-receptor chemical interaction and dose-response curves are examined.. Course Rotation: TBA. ... The principles of microbial diversity, disease and prevention, antibiotic resistance, vaccination, biological warfare and ...http://pace.smartcatalogiq.com/en/2012-2013/Undergraduate-Catalog/General-University/Course-Descriptions/BIO-Biology
Peregrine Pharmaceuticals Reports Data From Newly Published Research Reinforcing Potential of Targeting PS in HIV Infection -...
... targeting antibodies are expected to be less susceptible to the viral genomic mutations that lead to anti-viral drug resistance ... "These results indicate that targeting a host cell lipid such as PS as an anti-viral strategy is a promising concept of ... Drugs.com Mobile Apps. The easiest way to lookup drug information, identify pills, check interactions and set up your own ... Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and ...https://www.drugs.com/clinical_trials/peregrine-pharmaceuticals-reports-data-newly-published-research-reinforcing-potential-targeting-ps-9102.html
Peregrine Pharmaceuticals Presents Promising Antiviral Data at 2009 Chemical and Biological Defense Science & Technology ... ( ...
... antibodies are also expected to be much less susceptible to the viral genomic mutations that lead to antiviral drug resistance. ... suggesting that PS-targeting agents may provide a broad platform for treating viral infections. Because the PS target is host- ... the risk that PS-targeting antibodies will not be less susceptible to viral mutations and the risk that the results of clinical ... Phase I studies in HCV patients showed that bavituximab was well tolerated and it exhibited encouraging signs of anti-viral ...http://www.bio-medicine.org/biology-technology-1/Peregrine-Pharmaceuticals-Presents-Promising-Antiviral-Data-at-2009-Chemical-and-Biological-Defense-Science--26amp-3B-Technology-Conference-14897-1/
Discovery and development of integrase inhibitors - Wikipedia
... composed of both viral and host proteins. Integrase is a part of PIC's viral component. PIC's viral and host proteins are ... Many drugs have been discovered to treat the disease but mutations in the virus and resistance to the drugs make development ... Resistance of INI corresponds to those of other ARV drugs. First IN resistance is caused by primary mutations that decrease INI ... Integrase is a viral enzyme that integrates retroviral DNA into the host cell genome. Integrase inhibitors are a new class of ...https://en.wikipedia.org/wiki/Discovery_and_development_of_integrase_inhibitors
HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance - Arthur Olson
What novel HIV-Host interactions drive DNA replication and integration? 3. How does dynamics impact viral fitness and how can ... HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance Olson, Arthur J. Scripps Research Institute, ... implications of viral macromolecular interactions and dynamics and its broader impacts of the evolution of drug resistance. The ... We will explore resistance evolution in HIV as an opportune platform upon which to characterize the dynamic relationships ...http://grantome.com/grant/NIH/P50-GM103368-01
Resistance to the drug is achieved by amino acid changes in viral proteins that modulate cellular secretion. Similarly, herpes ... Recently several groups have explored the development of new antiviral drugs that target not viral proteins, but host proteins ... These drugs are used in various combinations of three, reducing the problem of drug resistance. The mutation rates among DNA ... The idea is that direct mutation of the drug target is not possible. Unfortunately, resistance to such drugs has been observed ...http://www.virology.ws/tag/dominant-negative/
HIV decision support: from molecule to man | Philosophical Transactions of the Royal Society of London A: Mathematical,...
Another potential scenario concerns the transmission of drug resistance at the population level. Viral load and infectivity can ... The VL hosts biomedical information related to viruses (proteins and mutations), patients (viral load, CD4 count, etc.) and ... Mutations in the viral protease that confer resistance to saquinavir increase the dissociation rate constant of the protease- ... The immune simulator takes as an input the viral load, the CD4+ count and the drug efficacy and then estimates the temporal HIV ...http://rsta.royalsocietypublishing.org/content/367/1898/2691