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*  Gonadotropin-releasing hormone antagonist - Wikipedia
GnRH antagonists are also being investigated in the treatment of women with hormone-sensitive breast cancer and some benign ... leading to a surge in testosterone or estrogen levels, GnRH antagonists have an immediate onset of action, rapidly reducing sex ... Gonadotropin-releasing hormone antagonists (GnRH antagonists) are a class of medications that antagonize the gonadotropin- ... clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone. Nat. Clin. Pract. Endocrinol. Metab.: 3: 157 ...
  https://en.wikipedia.org/wiki/Gonadotropin-releasing_hormone_antagonist
*  Antigonadotropin - Wikipedia
... including compounds acting on sex steroid hormone receptors such as progestogens, androgens, and estrogens (due to negative ... Antigonadotropins are used for a variety of purposes, including for the treatment hormonally-sensitive cancers, to delay ... both agonists and antagonists). However, many other drugs have antigonadotropic properties as well, ... follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This results in an inhibition of the hypothalamic-pituitary- ...
  https://en.wikipedia.org/wiki/Antigonadotropin
*  Poor ovarian reserve - Wikipedia
Gonadotropin-releasing hormone agonist/antagonist conversion with estrogen priming (AACEP) protocol. Fisch, Keskintepe and Sher ... This treatment protocol has also reversed some cases of iatrogenic POF caused by full body radiation treatment. Recently, two ... Fisch JD, Keskintepe L, Sher G (February 2008). "Gonadotropin-releasing hormone agonist/antagonist conversion with estrogen ... Variable success rate with treatment, very few controlled studies, mostly case reports. Treatment success strongly tends to ...
  https://en.wikipedia.org/wiki/Poor_ovarian_reserve
*  Elagolix - Wikipedia
Gonadotropin-releasing hormone receptor § Antagonists List of investigational hormonal agents § GnRH/gonadotropins Ezzati, ... As of 2017, it is in pre-registration for the treatment of endometriosis and phase III clinical trials for the treatment of ... Due to the suppression of estrogen levels by elagolix being incomplete, effects on bone mineral density are minimal, which is ... non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM) which is under development for ...
  https://en.wikipedia.org/wiki/Elagolix
*  Antiestrogen - Wikipedia
... and/or inhibiting or suppressing estrogen production. Antiestrogens are one of three types of sex hormone antagonists, the ... Antiestrogens are mainly used as a means of estrogen deprivation therapy in the treatment of ER-positive breast cancer. They ... Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like ... 7-. ISBN 978-3-0348-0664-0. V Craig Jordan (27 May 2013). Estrogen Action, Selective Estrogen Receptor Modulators and Women's ...
  https://en.wikipedia.org/wiki/Antiestrogen
*  Hormonal therapy (oncology) - Wikipedia
... class of hormonal therapy agents which act as antagonists of the estrogen receptor and are used primarily for the treatment and ... particularly steroid hormones, or drugs which inhibit the production or activity of such hormones (hormone antagonists). ... Hormone receptor antagonists bind to the normal receptor for a given hormone and prevent its activation. The target recepetor ... Leuprorelin and goserelin are GnRH analogs which are used primarily for the treatment of hormone-responsive prostate cancer. ...
  https://en.wikipedia.org/wiki/Hormonal_therapy_(oncology)
*  Fertility medication - Wikipedia
Estrogen antagonists or Gonadotropins. Either Gonadotropin-releasing hormone (GnRH) or any Gonadotropin-releasing hormone ... Although primarily a breast cancer treatment, aromatase inhibitors can also work as fertility medication, probably through a ... Estrogen antagonists and gonadotropins may stimulate multiple follicles and other ovarian hormones leading to multiple birth ... hMG is a medication containing a follicle-stimulating hormone (FSH) and a lutenizing hormone (LH). There currently are no ...
  https://en.wikipedia.org/wiki/Fertility_medication
*  Androgen deprivation therapy - Wikipedia
Orchiectomy, LHRH analogs and LHRH antagonists can all cause similar side effects, due to changes in the levels of sex hormones ... However, this treatment needs to be combined with radiation therapy (RT) because ADT itself does not eradicate the cancer; it ... Estrogen deprivation therapy Maximum androgen blockade Perlmutter and Lepor (2007). "Androgen Deprivation Therapy in the ... whereas LHRH antagonists decrease directly the amount of testosterone. Some of the most common LHRH agonist and antagonist ...
  https://en.wikipedia.org/wiki/Androgen_deprivation_therapy
*  Hormone therapy - Wikipedia
Hormone therapy or hormonal therapy is the use of hormones in medical treatment. Treatment with hormone antagonists may also be ... deprivation therapy for women with estrogen receptor-positive breast cancer High-dose estrogen therapy for women with estrogen ... The most general classes of hormone therapy are oncologic hormone therapy and hormone replacement therapy, of which there are ... of men or sex offenders with paraphilias or hypersexuality Growth hormone therapy for growth hormone deficiency Thyroid hormone ...
  https://en.wikipedia.org/wiki/Hormone_therapy
*  Fezolinetant - Wikipedia
"Optimization of Novel Antagonists to the Neurokinin‑3 Receptor for the Treatment of Sex-Hormone Disorders (Part II)". ACS ... NK3 receptor antagonists are anticipated as a useful clinical alternative to estrogens for management of hot flashes, but with ... receptor antagonist which is under development by Ogeda (formerly Euroscreen) for the treatment of sex hormone-related ... Unlike GnRH modulators, but similarly to estrogens, NK3 receptor antagonists including fezolinetant and MLE-4901 (also known as ...
  https://en.wikipedia.org/wiki/Fezolinetant
*  Menopause - Wikipedia
... and antagonist activity on breast and the endometrium. Tamoxifen is in widespread use for treatment of hormone sensitive breast ... Low-dose prescription vaginal estrogen products such as estrogen creams are generally a safe way to use estrogen topically, to ... Oestrogen and Progestin as Hormone Therapy Archived 11 July 2012 at the Wayback Machine. "Estrogen and progestogen use in ... In the context of the menopause, hormone replacement therapy (HRT) is the use of estrogen in women without a uterus and ...
  https://en.wikipedia.org/wiki/Menopause
*  Antihormone therapy - Wikipedia
Antihormone activity is usually achieved by antagonizing their function (with a hormone antagonist) and sometimes by preventing ... Antihormone treatment is thus often specific to sex. For example, androgen deprivation therapy using antiandrogens is important ... also can be treated with estrogen deprivation therapy using antiestrogens. Antiestrogens are not very effective for ovarian ... Antihormone therapy is a type of hormone therapy that suppresses selected hormones or their effects, in contrast with hormone ...
  https://en.wikipedia.org/wiki/Antihormone_therapy
*  Gonadotropin-releasing hormone agonist - Wikipedia
... pending treatment decisions in children with gender dysphoria Management of female disorders that are dependent on estrogen ... Usage of GnRH agonist for this purpose necessitates using a GnRH antagonist instead of a GnRH agonist for suppression of ... They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of ... the release of the pituitary hormones follicle-stimulating hormone (FSH) and luteinizing hormone (LH). However, after the ...
  https://en.wikipedia.org/wiki/Gonadotropin-releasing_hormone_agonist
*  Gynecomastia - Wikipedia
Estrogen acts as a growth hormone to increase the size of male breast tissue. The cause of gynecomastia is unknown in around 25 ... Selective estrogen receptor modulators (SERMs) such as tamoxifen, raloxifene, and clomifene may be beneficial in the treatment ... Other medications such as methadone, aldosterone antagonists (spironolactone and epelerenone), HIV medication, cancer ... Furthermore, estrogens can increase blood levels of the protein sex hormone-binding globulin (SHBG), which binds free ...
  https://en.wikipedia.org/wiki/Gynecomastia
*  Hot flash - Wikipedia
SERMs are a category of compounds that act selectively as agonists or antagonists on the estrogen receptors throughout the body ... More recent research points to mitochondrial uncoupling due to a lack of oestrogen. Hormone replacement therapy may relieve ... Tamoxifen, a drug used in the treatment of some types of breast cancer and which can cause hot flashes as a side effect, and ... Lignans are thought to have estrogen agonist and antagonist effects as well as antioxidant properties. Flaxseed and its lignans ...
  https://en.wikipedia.org/wiki/Hot_flash
*  Antiandrogen - Wikipedia
Msaouel P, Diamanti E, Tzanela M, Koutsilieris M (2007). "Luteinising hormone-releasing hormone antagonists in prostate cancer ... "Parenteral oestrogen in the treatment of prostate cancer: a systematic review". Br. J. Cancer. 98 (4): 697-707. doi:10.1038/sj. ... Gonadotropins include luteinizing hormone (LH) and follicle-stimulating hormone (FSH) and are peptide hormones that signal the ... N-Terminal domain AR antagonists are a new type of AR antagonist that, unlike all currently marketed AR antagonists, bind to ...
  https://en.wikipedia.org/wiki/Antiandrogen
*  Selective estrogen receptor modulator - Wikipedia
... has become the treatment of choice for women diagnosed with all stages of hormone-responsive breast cancer, that is, breast ... Thus, one compound can be an ER agonist in a tissue rich in coactivators but an ER antagonist in tissues rich in corepressors. ... SERM is also used in combination with conjugated estrogens indicated for the treatment of estrogen deficiency symptoms, and ... treatment and prevention of postmenopausal osteoporosis, treatment and reduction in risk of breast cancer and treatment of ...
  https://en.wikipedia.org/wiki/Selective_estrogen_receptor_modulator
*  Gonadotropin-releasing hormone - Wikipedia
"Short-term treatment of idiopathic precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. A ... GnRH antagonists) the gonadotropins. These synthetic analogs have replaced the natural hormone in clinical use. Its analogue ... GnRH release can also be regulated by estrogen. It has been reported that there are kisspeptin-producing neurons that also ... Luteinizing hormone-releasing hormone (LRH, LHRH) Follicle-stimulating hormone and luteinizing hormone-releasing factor (FSH/LH ...
  https://en.wikipedia.org/wiki/Gonadotropin-releasing_hormone
*  Augmentation (pharmacology) - Wikipedia
Giving an adenosine A2A receptor antagonist on top of existing treatment for Parkinson's disease. In other field of ... This might be done when someone is deficient in a hormone, enzyme or other endogenous substance. For example: To give α1 ... Prescribing estrogen for someone already being treated with antipsychotics for the management of Schizophrenia. ... Zhu, C; Wang, G; Li, J; Chen, L; Wang, C; Wang, Y; Lin, P; Ran, H (November 2014). "Adenosine A2A receptor antagonist ...
  https://en.wikipedia.org/wiki/Augmentation_(pharmacology)
*  Androgen-dependent condition - Wikipedia
67-. ISBN 978-0-8247-0887-0. Mariagrazia Stracquadanio; Lilliana Ciotta (20 April 2015). Metabolic Aspects of PCOS: Treatment ... Androgen deprivation therapy Androgen insensitivity syndrome Estrogen-dependent condition Spinal bulbar muscular atrophy Joseph ... gonadotropin-releasing hormone (GnRH) analogues such as leuprolide and cetrorelix, and/or other antigonadotropins such as ... including androgen receptor antagonists such as cyproterone acetate, spironolactone, and bicalutamide, 5α-reductase inhibitors ...
  https://en.wikipedia.org/wiki/Androgen-dependent_condition
*  Comparison of bicalutamide with other antiandrogens - Wikipedia
... bicalutamide is indicated for use in combination therapy with a Gonadotropin Releasing Hormone analog for the treatment of ... Due to increased estrogen levels, bicalutamide and other NSAAs are similarly associated with low rates of hot flashes (9.2% for ... In addition, they are not silent antagonists of the AR, but are rather weak partial agonists with the capacity for both ... "Non-steroidal antiandrogen monotherapy compared with luteinizing hormone-releasing hormone agonists or surgical castration ...
  https://en.wikipedia.org/wiki/Comparison_of_bicalutamide_with_other_antiandrogens
*  Relugolix - Wikipedia
Non-Peptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor". Journal of Medicinal Chemistry. 54 (14): 4998- ... are being studied in the treatment of endometriosis and uterine leiomyoma to achieve partial sex hormone suppression. The ... incidence and severity of menopausal symptoms such as hot flushes and to avoid bone mineral density changes caused by estrogen ... selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.12 nM) which is under development for ...
  https://en.wikipedia.org/wiki/Relugolix
*  Drospirenone - Wikipedia
Maclennan, A. H.; Broadbent, J. L.; Lester, S.; Moore, V. (18 October 2004). "Oral oestrogen and combined oestrogen/progestogen ... angiotensin II receptor antagonists, potassium-sparing diuretics, heparin, aldosterone antagonists, or NSAIDs), a potassium ... It is indicated for prevention of pregnancy as well as treatment of premenstrual dysphoric disorder for women who choose to use ... Drospirenone is an ingredient in some birth control pills and is used in menopausal hormone therapy. In combination with ...
  https://en.wikipedia.org/wiki/Drospirenone
*  Catamenial epilepsy - Wikipedia
Progesterone has been shown to lower the number of estrogen receptors, and thus act as an antagonist to estrogen actions. In ... as well as human-use of estrogen-based hormone replacement therapy, estrogens have been seen to increase the excitability of ... Several treatment methods have been determined exclusively for women with catamenial epilepsy. A great majority of these ... Estrone is the major estrogen after menopause, and this hormone may be very influential in seizure control of the catamenial ...
  https://en.wikipedia.org/wiki/Catamenial_epilepsy
*  Diethylstilbestrol - Wikipedia
DES has been identified as an antagonist of all three isotypes of the estrogen-related receptors (ERRs), the ERRα, ERRβ, and ... pregnancy Menopausal hormone therapy for the treatment of menopausal symptoms such as hot flashes and vaginal atrophy Hormone ... DES is an estrogen; specifically, it is a very potent full agonist of both of the estrogen receptors (ERs). It has ... Council on Drugs (1960). "Androgens and estrogens in the treatment of disseminated mammary carcinoma: retrospective study of ...
  https://en.wikipedia.org/wiki/Diethylstilbestrol