Predator-induced stress and the ecology of fear - Clinchy - 2012 - Functional Ecology - Wiley Online Library
Allostasis, Homeostasis and the Costs of Physiological Adaptation (ed. J. Schulkin), pp. 164-227. Cambridge University Press, ... Rosen, J.B. & Schulkin, J. (2004) Adaptive fear, allostasis, and the pathology of anxiety and depression. ... of the stress axis is to maintain homeostasis, chronic stress must be maladaptive and pathological, and hence cannot exist in ... sustained psychological stress', the physiological stress effects reported could also result from 'chronic physical challenges ...http://onlinelibrary.wiley.com/doi/10.1111/1365-2435.12007/full?globalMessage=0
Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
The UPR is tailored essentially to reestablish ER homeostasis also through adaptive mechanisms involving the stimulation of ... Various physiological and pathological conditions, including hypoxia, ER-. depletion, oxidative injury, high-fat diet, ... From ER Stress to Cell Death. When the initial cellular responses fail to restore ER homeostasis, sustained ER stress causes ... dependent and independent stress signals. Another -activated kinase that regulates autophagy in response to ER stress is the ...https://www.hindawi.com/journals/ijcb/2010/930509/
In Vivo Effect of Arsenic Trioxide on Keap1-p62-Nrf2 Signaling Pathway in Mouse Liver: Expression of Antioxidant Responsive...
Mammalian cells cope with xenobiotics by adaptive defense mechanisms to maintain cellular homeostasis and physiological ... Trace elements play an important role in maintaining normal homeostasis of the body. Oxidative stress results from changes in ... Oxidative stress is a relatively new theory in assessment of arsenic toxicity [51, 52]. Arsenic causes oxidative stress by ... involvement of cellular adaptive response to oxidative stress," Environmental Health Perspectives, vol. 118, no. 6, pp. 864-870 ...https://www.hindawi.com/journals/isrn/2013/817693/
Oxidative Stress, Prooxidants, and Antioxidants: The Interplay
... and oxidative stress. Distress differs from stress, which is a physiological reaction that can lead to an adaptive response [22 ... Today, stress can be defined as a process of altered biochemical homeostasis produced by psychological, physiological, or ... Stress is a commonly used term for oxidative stress. Any alteration in homeostasis leads to an increased production of these ... 5. Physiological Role of Stress. Stress has a significant ecological and evolutionary role and may help in understanding the ...https://www.hindawi.com/journals/bmri/2014/761264/
Reality as the leading cause of stress: rethinking the impact of chronic stress in nature - Boonstra - 2012 - Functional...
First, homeostasis was used for the coordinated physiological processes to maintain a steady state in an animal. This was ... If it is adaptive to be chronically stressed, they will evolve in that direction; if not, they will only respond acutely. If ... The Ecology Of Stress. Reality as the leading cause of stress: rethinking the impact of chronic stress in nature. Authors. *. ... A brief history of stress physiology and chronic stress. The history of how we have come to think of the role of stress in ...http://onlinelibrary.wiley.com/doi/10.1111/1365-2435.12008/full
Frontiers | Neural control of chronic stress adaptation | Frontiers in Behavioral Neuroscience
... likely due to altered limbic control of stress effector pathways. Stress-related disorders, such as depression and PTSD, are ... likely due to altered limbic control of stress effector pathways. Stress-related disorders, such as depression and PTSD, are ... The long-term impact of stress is kept in check by the process of habituation, which reduces HPA axis responses upon repeated ... The long-term impact of stress is kept in check by the process of habituation, which reduces HPA axis responses upon repeated ...https://www.frontiersin.org/articles/10.3389/fnbeh.2013.00061/full
All Hardgainers are Not Created Equal | T Nation
Skinny-fat hardgainers suffer from an overactive sympathetic nervous system, and an extreme hypersensitivity to stress of any ... This is the physiological system that kicked in when we had to escape predators back in the Paleolithic Age, and now takes over ... This intricate and highly adaptive response is known as the "fight or flight" response, and is mediated by one branch of your ... This is referred to as homeostasis, the body's ability to maintain a relatively constant internal environment. Anything from ...https://www.t-nation.com/training/all-hardgainers-are-not-created-equal
Amino acids regulate salinity-induced potassium efflux in barley root epidermis - Open Access Repository
in salt-stressed plants. The physiological relevance. of this phenomenon remains largely unknown.. Using the MIFE ion Xux ... on K+ homeostasis. Our results suggest that physiologically. relevant concentrations of free amino acids. might contribute to ... plant adaptive responses to salinity. by regulating K+ transport across the plasma membrane,. thus enabling maintenance of an ... plant damage by stress. Investigating the speciWc mechanisms. of such amelioration remains a key issue for. future studies. ...https://eprints.utas.edu.au/3857/
Developmental origins of non-communicable disease: Implications for research and public health | Environmental Health | Full...
... cellular plasticity and a variety of stress signals such oxidative and endoplasmic reticulum stress. These influence epigenetic ... If there is a mismatch between the adaptive change and the subsequent lifetime environment then the response will likely be in ... In both cases, alterations in physiological functions can be induced and may lead to the development of non-communicable ... In contrast, the human body has evolved mechanisms of developmental plasticity and homeostasis to cope with changes in ...https://ehjournal.biomedcentral.com/articles/10.1186/1476-069X-11-42
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Medicine, Issue 56, Stress, anxiety, laboratory stressor, cortisol, physiological response, psychological stressor ... Macrophages are critical components of the innate and adaptive immune responses, and they are the first line of defense against ... is actively involved in regulating cell and tissue function during development and organ homeostasis. It does so by acting via ... Of psychological stress protocols, meta-analysis suggests that the Trier Social Stress Test (TSST) is the most useful and ...https://www.jove.com/visualize/abstract/23431364/acute-stress-reduces-wound-induced-activation-microbicidal-potential
Transcriptional Regulation by Nuclear Corepressors and PGC-1α: Implications for Mitochondrial Quality Control and Insulin...
... energy homeostasis and metabolic function. The journal also welcomes preclinical and clinical trials of drugs that can modulate ... J. J. Wu, C. Quijano, E. Chen et al., "Mitochondrial dysfunction and oxidative stress mediate the physiological impairment ... N. Wu, L. Yin, E. A. Hanniman, S. Joshi, and M. A. Lazar, "Negative feedback maintenance of heme homeostasis by its receptor, ... indicating that this adaptive response requires ROS signal . Together, autophagy-dependent mitochondrial turnover in ...https://www.hindawi.com/journals/ppar/2012/348245/
Frontiers | Dissecting the Biochemical and Transcriptomic Effects of a Locally Applied Heat Treatment on Developing Cabernet...
These physiological alterations could be partly explained by the deep remodelling of transcriptome in heated berries. More than ... These physiological alterations could be partly explained by the deep remod... ... depending on the developmental stage and the stress duration. When applied at the herbaceous stage, HT delayed the onset of ... depending on the developmental stage and the stress duration. When applied at the herbaceous stage, HT delayed the onset of ...https://www.frontiersin.org/articles/10.3389/fpls.2017.00053/full
Antioxidants | Free Full-Text | 4-Hydroxynonenal in Redox Homeostasis of Gastrointestinal Mucosa: Implications for the Stomach...
... are important mediators in physiological adaptive reactions and signaling, but they are also thought to be implicated in the ... The health of the gastric epithelium highly depends on redox homeostasis, antioxidant defense, and activity of detoxifying ... or the relevance of antioxidants for HNE-related redox homeostasis in GM, still need more studies and new comprehensive ... Exercise-Induced Oxidative Stress and the Effects of Antioxidant Intake from a Physiological Viewpoint ...https://www.mdpi.com/2076-3921/7/9/118
Heinz Baumann, PhD | Roswell Park Comprehensive Cancer Center
Regulation of Gene Expression and Cell Proliferation by Hormones and Cytokines as Part of Homeostasis, Stress Response, ... The second program focuses on the genetics and biology of the hepatic acute phase response and the physiological role of the ... and direct the innate and adaptive immune responses. This laboratory pursues two long-term research programs. The first program ... Regulation of Gene Expression and Cell Proliferation by Hormones and Cytokines as Part of Homeostasis, Stress Response, ...https://www.roswellpark.org/heinz-baumann
IJMS | Free Full-Text | Oxidative Stress and Neurodegenerative Disorders | HTML
ROS at low or moderate concentration can play important physiological roles. However, an excessive amount of ROS under ... Thus, oxidative stress elicits various neurodegenerative diseases. In addition, chemotherapy could result in severe side ... In this review, we summarize the source, balance maintenance and physiologic functions of ROS, oxidative stress and its toxic ... The central nervous system (CNS) is particularly vulnerable to oxidative stress due to its high oxygen consumption, weakly ...http://www.mdpi.com/1422-0067/14/12/24438/htm
IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates
... and whether the physiological consequences of mRNA decay are adaptive or destructive. IRE1α was also linked to pro-apoptotic c- ... If ER stress is successfully reduced, negative feedback causes UPR signaling to wane as homeostasis becomes restored (Merksamer ... Moreover, all these compounds allow XBP1 mRNA splicing to proceed fully under ER stress. Under Tg-induced ER stress, APY29 ... These results argue that under low ER stress conditions, IRE1α preferentially splices XPB1, while at higher stress it also ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2762408/?lang=en-ca
Tissue stress - Wikipedia
This universal physiological reaction plays a role of TAS executive mechanism. Thus, the adaptive function of tissue stress is ... These effectors cause tissuespecific self-damage of homologous cells via disturbance of their ion homeostasis and energy- ... Tissue stress (tissue adaptive syndrome) is an unspecific adaptive reaction universal for all tissues of adult organism which ... two physiological functions of tissue stress, which are realized in the process of participation of its adaptive mechanism, can ...https://en.wikipedia.org/wiki/Tissue_stress
Rab7b modulates autophagic flux by interacting with Atg4B | EMBO Reports
... is a catabolic cellular process essential in several physiological processes such as maintenance of basal homeostasis, stress ... and innate and adaptive immunity , , , . During autophagy, cytosolic components are sequestered by unique double‐ ... The autophagic pathway maintains basal cellular homeostasis and helps cells adapt during stress; thus, defects in autophagy can ... Mizushima N (2009) Physiological functions of autophagy. Curr Top Microbiol Immunol 335: 71-84. ...http://embor.embopress.org/content/18/10/1727
AGENTS AND METHODS FOR TREATMENT OF ANXIETY DISORDERS - Patent application
0003]One of the physiological systems affected by stress is the immune system. The effects of stress on the immune system are ... enable the return to normal homeostasis when the source of stress is removed. However, when homeostasis is not restored and ... 2006). "Maladaptation to mental stress mitigated by the adaptive immune system via depletion of naturally occurring regulatory ... the body's physiological ability to cope with stress. REFERENCES Adamec, R. E., P. Burton, et al. (1999). "Unilateral ...http://www.patentsencyclopedia.com/app/20110033488
Allostatic load - Wikipedia
The physiological responses involved in the stress response are widely considered adaptive as they are effective at responding ... the stress response constantly disrupts homeostasis resulting in overexertion of physiological systems. Allostatic load can be ... Stress hormones such as epinephrine and cortisol in combination with other stress-mediating physiological agents such as ... Allostatic load is not unique to humans and may be used to evaluate the physiological effects of chronic or frequent stress in ...https://en.wikipedia.org/wiki/Allostatic_load
Npas4 Is a Novel Activity-Regulated Cytoprotective Factor in Pancreatic β-Cells | Diabetes
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006;313:1137 ... In the pancreatic β-cell, glucose is likely a physiological trigger that activates an adaptive response to stimulation, thereby ... Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress. ... it might be able to protect against ER stress without significant detrimental physiological effects. ...http://diabetes.diabetesjournals.org/content/62/8/2808?frame=sidebar&with-ds=yes
Nitric Oxide and Mitochondrial Signaling | Arteriosclerosis, Thrombosis, and Vascular Biology
88 its relevance to the role of NO in physiological homeostasis is far from clear. There are several reasons for this, ... whether these processes are linked to physiological signaling responses or represent an early sign of oxidative stress and ... 13 suggesting that mitochondria under the influence of NO may also be involved in the attenuation of adaptive responses to low ... arising from the involvement of the mitochondrion in physiological homeostasis. Despite these differences, some downstream ...http://atvb.ahajournals.org/content/27/12/2524.full
Empathy across species | Philosophical Transactions of the Royal Society B: Biological Sciences
... and a physiological stress response. Studies with humans document that the perception of another in pain or emotional distress ... Successful helping is followed by the reduction of distress, and return to homeostasis in the victim, and by proxy in the ... Anger, a social emotion, supports aggression, a behaviour that is often adaptive in an environment with limited resources. In ... 2015 Stress, social behavior, and resilience: insights from rodents. Neurobiol. Stress 1, 116-127. (doi:10.1016/j.ynstr.2014.10 ...http://rstb.royalsocietypublishing.org/content/371/1686/20150077
Comparative physiological and proteomic responses to drought stress in two poplar species originating from different altitudes ...
Comparative physiological and proteomic responses to drought stress in two poplar species originating from different altitudes ... Results revealed that the adaptive responses to drought stress vary between the two poplar species. As a consequence of drought ... redox homeostasis and sugar metabolism. Morphological consequences as well as physiological and proteomic responses to drought ... Physiological and proteomic responses to drought stress in poplar may work cooperatively to establish a new cellular ...http://www.spectroscopynow.com/details/ezine/sepspec24138ezine/Comparative-physiological-and-proteomic-responses-to-drought-stress-in-two-popla.html
emotion facts, information, pictures | Encyclopedia.com articles about emotion
These theories stressed the unique motivational, expressive, physiological, neurological, and feeling states of the basic ... His works introduced the idea that there were certain basic emotions and that emotions served adaptive functions-that is, that ... it plays its major role in maintaining homeostasis. (4) Cannon emphasized the utility of bodily changes in emotion, but many ... upon the general adaptation syndrome and the adjustments of the organism to stress [see STRESS]. ...https://www.encyclopedia.com/medicine/psychology/psychology-and-psychiatry/emotion