HLA A1-B8 haplotype - Wikipedia
Ambrus M, Hernádi E, Bajtai G (May 1977). "Prevalence of HLA-A1 and HLA-B8 antigens in selective IgA deficiency". Clin. Immunol ... HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07 ... A1-B8 serotype was associated with a number of diseases as "HL-A" antigens were first being described. Among these were ... April 1990). "A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection ...
RCSB PDB - 3BO8: The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide ... We have previously determined the structure of the MHC class I molecule HLA-A1 bound to a melanoma antigen-encoding gene (MAGE ... Here, we compare the X-ray structure of HLA-A1:MAGE-A1 with that complexed with Fab-Hyb3 to gain insight into structural ... Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like ...
SCOPe 2.08: Domain d2av7a1: 2av7 A:182-275
Uniprot P30685 25-300 ! Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor ! ... PDB Compounds: (A:) HLA class I histocompatibility antigen, A-2 alpha chain. SCOPe Domain Sequences for d2av7a1:. Sequence; ... Uniprot P30481 25-300 ! Uniprot P01892 25-298 ! Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 ... PDB Description: crystal structure of htlv-1 tax peptide bound to human class i mhc hla-a2 with the k66a mutation in the heavy ...
Primary Sclerosing Cholangitis: Background, Etiopathophysiology, Epidemiology
1, 10, 11] There is also an increased prevalence of HLA alleles A1, B8, and DR3 in PSC. [12, 13] ... most of which localize within the human leukocyte antigen (HLA) complex. [14] Subclassification of PSC patients according to ... 16] A genetic predisposition has been suggested because of an increased prevalence of HLA-B8, HLA-DR3, and HLA-Drw52a. Genome- ... specific for one or several antigens: useful markers for subtypes of ulcerative colitis and associated primary sclerosing ...
HLA-DQA1 gene: MedlinePlus Genetics
The HLA-DQA1 gene provides instructions for making a protein that plays a critical role in the immune system. Learn about this ... The HLA-DQA1 gene is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the ... HLA class II histocompatibility antigen, DQ alpha 1 chain. *HLA class II histocompatibility antigen, DQ alpha 1 chain precursor ... 01 or HLA-DQA1*05:05 bound to the protein produced from HLA-DQB1 gene variants known as HLA-DQB1*02:01 or HLA-DQB1*02:02. The ...
OPUS Würzburg | Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide...
... in HLA-A1/-A2/-B35-positive patients with treatment-refractory stage-IV metastatic melanoma. The study endpoints were survivin- ... M1c; p = 0.010), but not with patient age, HLA type, performance status, or vaccination regimen. Conclusion Survivin-specific T ... This has been mainly attributed to immune escape by antigen loss, rendering us in the need of new vaccination targets. Patients ... This has been mainly attributed to immune escape by antigen loss, rendering us in the need of new vaccination targets. Patients ...
Is treatment-resistant schizophrenia categorically distinct from treatment-responsive schizophrenia? a systematic review | BMC...
HLA) genotypes and found significantly higher HLA-A1 allele frequency for treatment-resistant patients [37]. In contrast, a ... conducted HLA typing and found no group difference in frequencies of different classes of antigens [38]. All treatment- ... Lahdelma L, Ahokas A, Andersson LC, Huttunen M, Sarna S, Koskimies S. Association between HLA-A1 allele and schizophrenia gene( ... but another found null results for a difference in HLA antigen types [38]. ...
PC-3 growing culture cells
Antigen expression. HLA A1, A9. Tumorigenic. Yes, in nude mice. Handling. Culture Medium. DMEM:Hams F12. ... HLA alleles HLA characterization is available from more than 200 cell lines. HLA class I -A, B, C, and Class II HLA-DPA1, -DPB1 ... cells have low testosterone-5-alpha reductase and acidic phosphatase activity and do not express the prostate-specific antigen ...
Nathan Croft - Outputs - Monash University
A comprehensive analysis of peptides presented by HLA-A1. Giam, K. L., Ayala-Perez, R., Illing, P. T. T., Schittenhelm, R. B., ... Human leukocyte antigen (HLA) B27 allotype-specific binding and candidate arthritogenic peptides revealed through heuristic ... Schittenhelm, R. B., Dudek, N. L., Croft, N. P., Ramarathinam, S. & Purcell, A. W., Mar 2014, In: Tissue Antigens. 83, 3, p. ... HLA peptide length preferences control CD8+ T cell responses. Rist, M. J., Theodossis, A., Croft, N. P., Neller, M. A., Welland ...
Home - LiverAtlas
HLA class I histocompatibility antigen, A-1 alpha chain. 1A01_HUMAN HLA class I histocompatibility antigen, A-3 alpha chain ...
Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level. - Nuffield...
In our cohort of subjects with chronic HCV infection (genotype 1b or 3a), it is a frequently recognized CD8 epitope in HLA-A*01 ... Comparison of HCV sequences from Asia and Europe suggests that the frequency of the HLA-A*01 allele in a population may ... The predominant Y1444F substitution seemingly impairs binding to the HLA-A*01 molecule, which may have an important impact on ... The aim of this study was to characterize the forces that contribute to viral evolution in an HLA-A*01-restricted epitope in ...
Adhesion of immune cells | Benny Geiger's
Faculty Directory › UConn Health
... peptide antigen encoded by the MAGE-1 gene by granulocyte/macrophage-colony-stimulating-factor-cultured macrophages from HLA-A1 ... Activation induced cell death (AICD) of human melanoma antigen-specific TCR engineered CD8 T cells involves JNK, Bim and p53. ... Antigen presentation by MART-1 adenovirus-transduced interleukin-10-polarized human monocyte-derived dendritic cells. Mehrotra ... Cross-presentation of a human tumor antigen delivered to dendritic cells by HSV VP22-mediated protein translocation. Chhabra, ...
Polymyositis: Background, Etiology, Epidemiology
An increased association of myositis has been found with human leukocyte antigen (HLA) haplotypes A1, B8, and DR3, which also ... The most important antigenic targets of the MAA are the PM/Scl nucleolar antigen, the nuclear Ku antigen, the small nuclear ... The Jo-1 antigen is histidyl-tRNA synthetase. This enzyme is partially responsible for attaching tRNA to their cognate ... The anti-Jo-1 response appears to be self-antigen driven, having a broad spectrotype over time and undergoing isotype switching ...
Human Leukocyte Antigen (HLA) System - Immunology; Allergic Disorders - MSD Manual Professional Edition
HLA) System - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional ... HLA-A1, -B5, -C1, -DR1). Alleles defined by DNA sequencing are named to identify the gene, followed by an asterisk, numbers ... The heavy chain of the class I molecule is encoded by genes at HLA-A, HLA-B, and HLA-C loci. T cells that express CD8 molecules ... Individual serologically defined antigens encoded by the class I and II gene loci in the HLA system are given standard ...
Myasthenia Gravis: Practice Essentials, Background, Anatomy
HLA) types have a genetic predisposition to autoimmune diseases. The histocompatibility complex profile includes HLA-A1, -A3, - ... The exact mechanism of loss of immunologic tolerance to AChR, a self-antigen, is not understood. MG can be considered a B cell- ... These are then linked to MHC-II, the molecule required for reactivity to "self-antigens." The AChR antigenic fragment and MHC ... Sensitization to a foreign antigen that has cross-reactivity with the nicotinic ACh receptor has been proposed as a cause of ...
Dermatitis herpetiformis and latent celiac disease in two siblings | [Dermatite erpetiforme e malattia celiaca silente in due...
Subjects presenting with both CD and DH generally show an HLA pattern in which A1, B8, DR2, DR7, DQw2 are the most frequent ... DQw2 are the most frequent antigens one can find. We report about 2 brothers presenting with DH, clinically asymptomatic, ... Both the brothers had the same HLA pattern: A1, B8, DR3-DR2, DQw2. Our clinical study suggests that it is very important, ... Both the brothers had the same HLA pattern: A1, B8, DR3-DR2, DQw2. Our clinical study suggests that it is very important, ...
EFFECT OF IMMUNOSUPPRESSIVE DRUGS IN THE CONTEXT OF GVHD ON VIRUS SPECIFIC T CELLS - Project topics materials
They reported that antigen specific proliferation of T cells and cytotoxicity of HLA-A1 antigen specific CTL line were only ... In contrast, IFNγ-capture approach can select both CD4+ and CD8+ antigen-specific T cells in an HLA unrestricted manner. ... Multimers are most readily made with class I HLA and can only select CD8+ T cells but not CD4+ T-cell subset restricted by ... Virus-specific T cells by HLA-peptide multimers. To our knowledge, three investigators[76, 106-108] reported the treatment of ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D23.50.705.552.100.400 HLA-A1 Antigen D23.50.301.500.400.370.372 D12.776.395.550.489.400.10 D23.50.301.500.450.370.372 D12.776. ... D12.776.543.750.705.222.500 Antigens, CD70 D12.776.543.550.172 D12.776.543.550.170 Antigens, CD8 D23.50.301.264.35.108 Antigens ... E1.370.225.750 HLA-A Antigens D23.50.301.500.400.370 D12.776.395.550.489.400 D23.50.705.552.400.370 D12.776.543.550.421.400 ... D23.50.705.552.100.600 HLA-D Antigens D23.50.301.500.410.400 D12.776.395.550.509.400 D12.776.543.550.423.400 D23.50.301.500. ...
EXPERIMENTAL AND CLINICAL TRANSPLANTATION
A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report ... These HLA antigens are a well-known group of genes that produce interferon. It also has been suggested that a specific HLA-C ... There have been 10 cases in which the absence of human leukocyte antigen- (HLA-) C7 allele (a genetic trait) was observed in ... Human leukocyte antigen Cw7 was detected in 4 of 5 recipients, and the fifth case, the antigen was detected in the donor. At ...
Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma...
H-2 Antigens, HLA-A1 Antigen, HLA-A2 Antigen, Histocompatibility Antigen H-2D, Leukocyte Count, Male, Melanoma, Experimental, ...