*  2rny - Proteopedia, life in 3D
Chromosomal protein , Creb , Disease mutation , Dna-binding , Histone , Host-virus interaction , Metal-binding , Methylation , ... Acetylation and modulation of erythroid Kruppel-like factor (EKLF) activity by interaction with histone acetyltransferases. ... Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its ... Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation. J Biol Chem. 2001 Apr 6;276(14):10715-21. ...
  http://proteopedia.org/wiki/index.php/2rny
*  IJMS | Free Full-Text | ANRIL: Molecular Mechanisms and Implications in Human Health | HTML
Li, Q.; Xiao, H.; Isobe, K. Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein p300 in tissues of ... ANRIL has been shown to specifically bind two polycomb proteins: CBX7 (PRC1) and SUZ12 (PRC2) [25,26,42], to regulate histone ... Polycomb proteins are a group of proteins involved in transcriptional gene repression via two distinct histone modifications: ... The gene up-regulated the most was RREB1 (Ras responsive element binding protein) [49], a transcription factor that binds to ...
  http://www.mdpi.com/1422-0067/14/1/1278/htm
*  IJMS | Free Full-Text | Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases | HTML
... histone modifications and DNA-methylation is, in fact, typically associated with the ageing process. Specifically, ageing ... Li, Q.; Xiao, H.; Isobe, K. Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues ... Expression levels of the histone acetyltransferases, p300 and cAMP-responsive element-binding protein-binding protein (CBP), ... the histone acetyltransferases (HATs) and their counterpart, the histone deacetylases (HDACs), or the histone ...
  http://mdpi.com/1422-0067/14/9/17643/htm
*  JCI - Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism
... p300/cAMP response element binding protein-binding protein coactivator recruitment and histone acetyltransferase activity. Mol ... physical activity, RMR, and brown adipose tissue (BAT) uncoupling protein 1 (Ucp1) mRNA levels (Figure 3, C-G). While both ... E) Physical activity of control and AT1ALepR-KO mice on a chow diet (n = 10 control mice; n = 9 AT1ALepR-KO mice). (F and G) ... Leptin regulates ACE activity in mice. J Mol Med. 2010;88(9):899-907.. View this article via: PubMed CrossRef Google Scholar ...
  https://www.jci.org/articles/view/88641
*  TAF1 Gene - GeneCards | TAF1 Protein | TAF1 Antibody
Protein Coding), TATA-Box Binding Protein Associated Factor 1, including: function, proteins, disorders, pathways, orthologs, ... Binding to TAF1 or CIITA inhibits the histone acetyltransferase activity. *TAF1_HUMAN,P21675 ... TATA-Box Binding Protein Associated Factor 1 2 3 5 * TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, ... Exhibits histone acetyltransferase activity towards histones H3 and H4 (PubMed:15870300). *TAF1_HUMAN,P21675 ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=TAF1
*  Faculty of Medicine - Faculty of Medicine, Memorial University of Newfoundland
The transcriptional cofactor MIER1-beta negatively regulates histone acetyltransferase activity of the CREB-binding protein. ... 5. Thorne, L.B., McCarthy, P.L., Paterno, G.D. and L.L. Gillespie 2008 Protein expression of the transcriptional regulator MI- ... a interacting protein, is associated with breast cancer progression. Br J Cancer, 99, 639-646. ...
  http://www.med.mun.ca/Medicine/Faculty/Gillespie,-Laura.aspx
*  Recombinant Human MGEA5 protein (ab153117) | Abcam
Ab153117 is a full length protein produced in Wheat germ and has been validated in WB, ELISA. Abcam provides free… ... Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714).. Isoform 3: Cleaves GlcNAc but ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ... The Universal Protein Resource (UniProt) in 2010. Nucleic Acids Res. 38:D142-D148 (2010) . ...
  http://www.abcam.com/recombinant-human-mgea5-protein-ab153117.html
*  Mgea5 - Protein O-GlcNAcase - Rattus norvegicus (Rat) - Mgea5 gene & protein
Does not bind acetyl-CoA and does not have histone acetyltransferase activity. ... Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc ... Does not bind acetyl-CoA and does not have histone acetyltransferase activity.By similarity. ,p>Manually curated information ... The protein has apparent histone acetyltransferase activity when expressed in mammalian cells, but not when expressed in ...
  http://www.uniprot.org/uniprot/Q8VIJ5
*  CREB Binding Protein Functions During Successive Stages of Eye Development in Drosophila | Genetics
2001 The HOX homeodomain proteins block CBP histone acetyltransferase activity. Mol. Cell. Biol. 21: 7509-7522. ... Murata, T., R. Kurokawa, A. Krones, K. Tatsumi, M. Ishii et al., 2001 Defect of histone acetyltransferase activity of the ... Drosophila CREB binding protein (CBP), which is encoded by the nejire (nej) locus, belongs to the CBP/p300 family of proteins ( ... Since each CBP truncated protein retains a different set of protein domains, the expression of each variant protein is expected ...
  http://www.genetics.org/content/168/2/877
*  Tissue expression of KAT14 - Summary - The Human Protein Atlas
Estimation of protein expression could not be performed. View primary data. ... GO:0004402 [histone acetyltransferase activity]. GO:0005515 [protein binding]. GO:0005634 [nucleus]. GO:0005671 [Ada2/Gcn5/Ada3 ... GO:0004402 [histone acetyltransferase activity]. GO:0005515 [protein binding]. GO:0005634 [nucleus]. GO:0005671 [Ada2/Gcn5/Ada3 ... N-acetyltransferase activity]. GO:0016573 [histone acetylation]. GO:0030274 [LIM domain binding]. GO:0043966 [histone H3 ...
  http://www.proteinatlas.org/ENSG00000149474-KAT14/tissue/vulva%252Fanal+skin
*  Faculty Briefs - 2009
... factor CCN1/Cyur61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase." Journal ... 2009). "General RNA-binding proteins have a function in poly(A)-binding protein-dependent translation." EMBO Journal 28(1): 58- ... 2009). "Positional effects of monofluorinated phenylalanines on histone acetyltransferase stability and activity." Bioorganic ... 2009). "Relation of baseline plasma phospholipids transfer protein (PLTP) activity to left ventricular systolic dysfunction in ...
  http://library.downstate.edu/resources/facultybriefs2009.htm
*  Role of cAMP Response Element Binding Protein in Cardiovascular Remodeling | Arteriosclerosis, Thrombosis, and Vascular Biology
CBP is a transcriptional coactivator with histone acetyl transferase activity that activates gene transcription. CBP also ... Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and ... Acetylation of cAMP-responsive element-binding protein (CREB) by CREB-binding protein enhances CREB-dependent transcription. J ... A dominant repressor of cyclic adenosine 3′,5′-monophosphate (cAMP)-regulated enhancer-binding protein activity inhibits the ...
  http://atvb.ahajournals.org/content/26/3/449
*  Most recent papers with the keyword Promoter proximal pausing | Read by QxMD
Here, we identify a novel activity of the histone acetyltransferase p300/CREB-binding protein (CBP) in regulating promoter- ... We found that the Hox proteins AbdA and Ubx target gene promoters previously bound by the transcription pausing factor M1BP, ... Heat-shock proteins (HSPs) belong to the chaperone protein family whose expression is induced by different stresses including ... Two histone marks on histone H3, lysine 4 trimethylation (H3K4me3) and lysine 9 acetylation (H3K9ac), co-localize on active ...
  https://www.readbyqxmd.com/keyword/74751
*  Plus it
... both large proteins with histone acetyl transferase activity (17) . Smad complexes have also been shown to interact with ... at least in part through the recruitment of the general coactivators p300/cAMP response element-binding protein-binding protein ... Ski, SnoN, and c-Myc protein expression by Western blot using 20 μg of total cellular protein per sample. Western blots were ... possibly through Rho-like GTPases and TGF-β-activated kinase 1-binding protein 1/TGF-β-activated kinase 1 cascade, ultimately ...
  http://cancerres.aacrjournals.org/content/63/6/1413
*  GCN5L2 - Wikipedia
... of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein ... of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein ... Wang L, Mizzen C, Ying C, Candau R, Barlev N, Brownell J, Allis CD, Berger SL (1997). "Histone acetyltransferase activity is ... "Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and ...
  https://en.wikipedia.org/wiki/GCN5L2
*  TADA2L - Wikipedia
... of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein ... Wang L, Mizzen C, Ying C, Candau R, Barlev N, Brownell J, Allis CD, Berger SL (Jan 1997). "Histone acetyltransferase activity ... Wang L, Mizzen C, Ying C, Candau R, Barlev N, Brownell J, Allis CD, Berger SL (Jan 1997). "Histone acetyltransferase activity ... The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone ...
  https://en.wikipedia.org/wiki/TADA2L
*  NCOA1 - Nuclear receptor coactivator 1 - Sus scrofa (Pig) - NCOA1 gene & protein
Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a ... Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- ... ligand-dependent nuclear receptor transcription coactivator activity Source: GO_Central. *nuclear hormone receptor binding ... Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a ...
  http://www.uniprot.org/uniprot/Q4PJW2
*  CREB-binding protein - Wikipedia
The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize ... Zhang Q, Vo N, Goodman RH (July 2000). "Histone binding protein RbAp48 interacts with a complex of CREB binding protein and ... This protein acetylates both histone and non-histone proteins. This protein shares regions of very high-sequence similarity ... "Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein ( ...
  https://en.wikipedia.org/wiki/CREB-binding_protein
*  SND1 - Wikipedia
... protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and ... SND1 is Tudor Domain containing protein and Tudor Proteins are highly conserved proteins and even present in Drosophila ... Staphylococcal nuclease domain-containing protein 1 also known as 100 kDa coactivator or Tudor domain-containing protein 11 ( ... a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex". Proceedings of the National Academy of ...
  https://en.wikipedia.org/wiki/SND1
*  Gene Info
MF] DNA binding *[MF] acetyltransferase activity *[MF] histone acetyltransferase activity *[MF] metal ion binding *[MF] protein ... MYST histone acetyltransferase (monocytic leukemia) 4. 9056988. Full Length. BC150618. MYST histone acetyltransferase ( ... MYST histone acetyltransferase (monocytic leukemia) 4. 4761825. Incomplete. BC014143. MYST histone acetyltransferase (monocytic ... BP] histone H3 acetylation *[BP] histone acetylation *[BP] negative regulation of transcription, DNA-dependent *[BP] nucleosome ...
  https://cgap.nci.nih.gov/Genes/GeneInfo?ORG=Hs&CID=740873
*  Epigenetics of depression - Wikipedia
... various signaling pathways result in recruitment of CREB binding proteins, which have intrinsic histone acetyltransferase ... and Methyl CpG Binding Protein 2 (MeCP2) recruitment to the GDNF promoter. Increased HDAC activity results in a reduction of ... which has histone acetyltransferase ability. This results in less acetylation of the histones, which has been shown to be a ... There are a wide number of activities and histone alterations that are related with depression. Chronic stress was found to ...
  https://en.wikipedia.org/wiki/Epigenetics_of_depression
*  Ku80 - Wikipedia
... of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein ... binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". J. ... Ko L, Cardona GR, Chin WW (May 2000). "Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions ... Gell D, Jackson SP (September 1999). "Mapping of protein-protein interactions within the DNA-dependent protein kinase complex ...
  https://en.wikipedia.org/wiki/Ku80
*  NFE2L2 - Wikipedia
... but bind to a different protein called cAMP Response Element Binding Protein (CREB), which possesses intrinsic histone ... acetyltransferase activity. The Neh6 domain may contain a degron that is involved in the degradation of Nrf2, even in stressed ... In the nucleus, it combines (forms a heterodimer) with one of small Maf proteins (MAFF, MAFG, MAFK) and binds to the ... Nrf2 is a basic leucine zipper (bZIP) protein that regulates the expression of antioxidant proteins that protect against ...
  https://en.wikipedia.org/wiki/NFE2L2
*  Emerging Anticancer Therapeutic Targets and the Cardiovascular System | Circulation Research
73 Acetylation of histone by histone acetyltransferases (HATs) at amino-terminal tails loosens histone binding and promotes ... and oncogenic proteins.141 UP-S activity requires a sequential process, with multiple steps serving as potential target for ... Heat shock protein (Hsp)90 assists protein folding, stabilizing the 'client' protein, and preventing aggregation of denatured ... and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. J Biol Chem ...
  http://circres.ahajournals.org/content/106/6/1022
*  Differential function of genes regulated by VEGF-NFATc1 signaling pathway in migration of pulmonary valve endothelial cells
... and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. J Biol Chem ... C-terminal binding protein 1. CCL2. chemokine ligand 2. IGFBP. insulin-like growth factor binding protein. KDR. kinase insert ... Insulin-like growth factor 1 binding protein 3 synthesis by aortic endothelial cells is a function of cell density. Biochem ... Insulin-like growth factor binding protein (IGFBP)-2 was recently identified as an angiogenic or cardiogenic molecule in ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2810463/