Microcirculation changes following acute and chronic portal hypertension and their response towards bacterial translocation...
Increasing evidence relates them to the higher susceptibility to bacterial translocation (BT) by liver dysfunction and ... Portal Hypertension Mesenteric Lymph Node Peritoneal Fluid Bacterial Translocation Multiorgan Dysfunction Download article PDF ... Microcirculation changes following acute and chronic portal hypertension and their response towards bacterial translocation ... Bacterial challenge in the a-PH state showed that the liver, spleen and kidney go into a hypoperfusion state (-38, -45.2 and - ...https://rd.springer.com/article/10.1186/cc7051
Curative Resection of Hepatocellualr Carcinoma Using Modified Glissonean Pedicle Transection versus the Pringle Maneuver: A...
The Pringle maneuver is also associated with high risks of bacterial translocation, intrahepatic metastases, impaired liver ... The management of HCC is a huge challenge due to the complicating background liver disease and the high rate of recurrence 2. ... Chinese patients have the highest HCC morbidity and mortality rates in the world, with over 75% of these patients having large ... patients undergoing the Pringle maneuver experienced a significantly higher but transient total bilirubin concentration ...http://www.medsci.org/v09p0843.htm
Increased transperitoneal bacterial translocation in laparoscopic surgery.
Low pressure also was associated with increased bacterial translocation, as compared with high pressure, but beyond 30 min of ... Bacterial Translocation*. Carbon Dioxide / administration & dosage. Escherichia coli / isolation & purification, physiology. ... CONCLUSIONS: The risk of bacterial translocation in the E. coli rat peritonitis model is increased with insufflation using CO2 ... In the low-pressure groups of both gases (helium and CO2), bacterial translocation was significantly increased, as compared ...http://www.biomedsearch.com/nih/Increased-transperitoneal-bacterial-translocation-in/12802657.html
Gut Microbial Translocation in Critically Ill Children and Effects of Supplementation with Pre- and Pro Biotics
A high proportion of bacterial translocation in neonates results not only from immaturity of host defense functions, but also ... 3. Concepts of Bacterial Translocation. Bacterial translocation has been defined as the process by which live bacteria, their ... 4. Bacterial Translocation in Critically Ill Patients. Few studies have investigated the pathogenic potential of bacterial ... Several factors may enhance bacterial translocation in critically ill children. Bacterial overgrowth and breakdown of a tight ...https://www.hindawi.com/journals/ijmicro/2012/151393/
Sickle cell vaso-occlusive crisis: it's a gut feeling | Journal of Translational Medicine | Full Text
Both bacterial translocation and intestinal dysbiosis likely contribute to the higher levels of circulating activated ... compromised intestinal barrier renders SCD patients more susceptible to recurrent translocation by bacterial inoculums not high ... and therapies to reduce bacterial burden and translocation.. In conclusion, VOC may now join the ever-expanding list of ... Additional support for involvement of the microbiota in SCD stems from the observation that SCD patients have higher numbers of ...https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-1092-5
Necrotizing enterocolitis is associated with acute brain responses in preterm pigs | Journal of Neuroinflammation | Full Text
... and high risk of bacterial translocation . Some of the pigs in Si-NEC group also had NEC lesions in the colon, yet the ... 1a). Piglets with NEC in any region of the GIT tended to have higher brain wet weight (p = 0.07, Fig. 1b), probably due to ... 1f). Plasma glucose levels tended to be higher in Si-NEC pigs than in No NEC pigs (p = 0.06; Additional file 2: Table S1). ... 2a). Supporting these findings, treatment with CSF samples from both NEC groups of pigs resulted in a significantly higher ...https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-018-1201-x
Frontiers | Bacterial Translocation - Impact on the Adipocyte Compartment | Immunology
A high local expression of M-CSF might add to the enrichment of CD163+ M2 macrophages observed in the creeping fat of CD (75). ... bacterial translocation. Citation: Kruis T, Batra A and Siegmund B (2014) Bacterial translocation - impact on the adipocyte ... the effect of the NOD2 variants on bacterial translocation was characterized in patients. As compared to controls bacterial ... Bacterial translocation - impact on the adipocyte compartment. Tassilo Kruis, Arvind Batra and Britta Siegmund* ...https://www.frontiersin.org/articles/10.3389/fimmu.2013.00510/full
Frontiers | HigB of Pseudomonas aeruginosa Enhances Killing of Phagocytes by Up-Regulating the Type III Secretion System in...
... contain higher levels of T3SS proteins and display increased cytotoxicity to macrophage compared to vegetative bacterial cells ... Activation of toxins of bacterial toxin-antitoxin systems inhibits bacterial growth and plays an important role in persister ... Activation of toxins of bacterial toxin-antitoxin systems inhibits bacterial growth and plays an important role in persister ... Overexpression of HigB increased the expression of T3SS genes as well as bacterial cytotoxicity. We further demonstrate that ...https://www.frontiersin.org/articles/10.3389/fcimb.2016.00125/full
Poolesville High School Student Success 2015-16
Gayane Matevosyan, "Translocation Kinetics of Bacterial RNA Polymerase". Caroline Lent, "Generation of Transparent Nanopaper ... announces the winners of its annual High School Programming Contest. Poolesville High School finished third. IDT's annual ... This page is maintained by the Poolesville High School's Web Team ©1995-2017 MCPS, 850 Hungerford Drive, Rockville, Maryland ... The Poolesville High School team, coached by Mark Estep, consisted of Sophomores Cindy Chen, Parth Oza, Jagan Prem, and Kevin ...http://www.montgomeryschoolsmd.org/schools/poolesvillehs/about/success20152016.aspx
Increased transperitoneal bacterial translocation in laparoscopic surgery
Low pressure also was associated with increased bacterial translocation, as compared with high pressure, but beyond 30 min of ... The risk of bacterial translocation in the E. coli rat peritonitis model is increased with insufflation using CO2 or helium, ... There is increased risk of bacterial translocation in comparing groups that underwent pneumoperitoneum with those that did not ... In the low-pressure groups of both gases (helium and CO2), bacterial translocation was significantly increased, as compared ...https://insights.ovid.com/surgical-endoscopy/send/2003/09/000/increased-transperitoneal-bacterial-translocation/25/00010753
Portal Hypertension Promotes Bacterial Translocation in Rats Mono- and Non Mono-Associated with Escherichia Coli C25
PHT induces BT to mesenteric lymph nodes and this may account for the high incidence of septic complications associated witti ... Portal Hypertension Promotes Bacterial Translocation in Rats Mono- and Non Mono-Associated with Escherichia Coli C25. Jean- ... The hypothesis that PHT induces bacterial translocation (BT) was tested in a rat model with or without mono-association with ... In this model, the addition of HS to PHT leads to an increased mortality but without uniform translocation of the gut flora ...https://www.hindawi.com/journals/hpb/1994/057549/abs/
Frontiers | Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice | Immunology
This effect was associated with lower levels of Akkermansia and higher levels of TM7 bacteria and Proteobacteria in the aged ... microbiota promoted inflammation in the small intestine in the germ-free mice and enhanced leakage of inflammatory bacterial ... This effect was associated with lower levels of Akkermansia and higher levels of TM7 bacteria and Proteobacteria in the aged ... Here we show by transferring aged microbiota to young germ-free mice that certain bacterial species within the aged microbiota ...https://www.frontiersin.org/articles/10.3389/fimmu.2017.01385/full
Potential Application of Probiotics in the Prevention and Treatment of Inflammatory Bowel Diseases
... lower bacterial translocation to the liver and the prevention of damage to the large intestines . This is in agreement ... In a similar study, it was shown that the relapse rate in both groups was markedly higher than the investigators anticipated, ... Bacterial DNA has been shown to have potent immunostimulatory effects. It was reported that bacterial DNA could attenuate ... M. Akhtar, J. L. Watson, A. Nazli, and D. M. McKay, "Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF- ...https://www.hindawi.com/archive/2011/841651/
Study Shows Grapefruit Extract Helps Heal Stomach Ulcers
Female rats fed alcohol in the high fat fish oil (NFO) diet had significantly greater bacterial translocation (escape of ... Researchers determined injury to the intestine by measuring bacterial translocation and blood endotoxin levels, and also the ... without bacterial translocation nor elevation of endotoxin levels.. 'Our research suggests that women should be cautious about ... in a higher carbohydrate diet (LDC) or a low-carb, higher fat diet (NFO) for a total of eight weeks. ...http://www.prohealth.com/library/showarticle.cfm?libid=6937
Association of markers of bacterial translocation with immune activation in decompensated cirrhosis. | Sigma-Aldrich
In patients without signs of SBP or positive cultures, we found a high frequency of bDNA but low concordance of bDNA between ... Bacterial translocation (BT) may cause infections, in particular, spontaneous bacterial peritonitis (SBP). In the absence of ... Association of markers of bacterial translocation with immune activation in decompensated cirrhosis.. [Christian Mortensen, ... Bacterial DNA (bDNA) is claimed to be a promising surrogate marker for BT, although its clinical relevance has been questioned ...https://www.sigmaaldrich.com/catalog/papers/25357217
Effects of intra-abdominal pressure increase on intestinal ischemia and bacterial translocation in experimental sepsis model.
RESULTS: Fever and leukocyte values were considered high in Groups 3 and 4 compared with Groups 1 and 2 (p=0.001). The ...http://www.biomedsearch.com/nih/Effects-intra-abdominal-pressure-increase/21858390.html
Load-sensitive coupling of proton translocation and torque generation in the bacterial flagellar motor - Che - 2013 - Molecular...
Ryu, W.S., Berry, R.M., and Berg, H.C. (2000) Torque-generating units of the flagellar motor of Escherichia coli have a high ... Load-sensitive coupling of proton translocation and torque generation in the bacterial flagellar motor. ... mutation to probe the bacterial flagellar motor dynamics coupled with proton translocation. J Bacteriol 190: 6660-6667.. * ... Load-sensitive coupling of proton translocation and torque generation in the bacterial flagellar motor. Molecular Microbiology ...http://onlinelibrary.wiley.com/doi/10.1111/mmi.12453/references
Luminal lactate in acute pancreatitis - validation and relation to disease severity
... bacterial translocation is considered as the key event leading to infection of necrotic pancreatic tissue and high severity of ... This is potentially associated with bacterial translocation from the gut leading to local and systemic inflammation. In acute ... Results: High rectal luminal lactate was associated with low mucosal partial tension of oxygen (R = 0.57, p = 0.005) thereby ... Low precision and high bias was observed between two lactate analyzers. Conclusions: The association between rectal luminal ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:565719
Interaction between bacterial outer membrane proteins and periplasmic quality control factors: a kinetic partitioning mechanism...
The aqueous environment of the periplasmic space and high permeability of the outer membrane engender such a translocation ... Interaction between bacterial outer membrane proteins and periplasmic quality control factors: a kinetic partitioning mechanism ... Interaction between bacterial outer membrane proteins and periplasmic quality control factors: a kinetic partitioning mechanism ... Interaction between bacterial outer membrane proteins and periplasmic quality control factors: a kinetic partitioning mechanism ...http://www.biochemj.org/content/438/3/505
Lactobacillus Plantarum 299v in Colon Surgery - Tabular View - ClinicalTrials.gov
Bacterial translocation [ Time Frame: During surgery ]. *Inflammatory response (cytokines) [ Time Frame: Preoperative, during ... The purpose with this study was to find whether high doses of Lactobacillus plantarum 299v affects the potentially pathogenic ... have been shown to reduce bacterial translocation in animal studies. However, in humans studies results have varied. ... bacterial translocation and cell proliferation in patients undergoing planned colon surgery.. ...https://clinicaltrials.gov/ct2/show/record/NCT00695461?view=results
1187 High Intestinal Mucosal Injury Associating with Low Anti Endotoxine Immunity in Very Low Birth Weight Infants | Archives...
The intestinal permeability is increased in bacterial translocation which can lead to endotoxemia and multiple organ failure. ... 1187 High Intestinal Mucosal Injury Associating with Low Anti Endotoxine Immunity in Very Low Birth Weight Infants ... 1187 High Intestinal Mucosal Injury Associating with Low Anti Endotoxine Immunity in Very Low Birth Weight Infants ... Significant high urine i-FABP concentration was observed in died infants of second group (2.39±0.88 ng/ml, p,0.05). In contrast ...http://adc.bmj.com/content/97/Suppl_2/A340.1
Lactobacillus reuteri - Wikipedia
This leaking, known as bacterial "translocation", can lead to lethal conditions such as sepsis. In humans, translocation is ... Commercial turkeys fed L. reuteri from birth had nearly a 10% higher adult body weight than their peers raised in the same ... In rodent studies, L. reuteri was found to greatly reduce the amount of bacterial translocation following either the surgical ... one of which is bacterial translocation. In mice, the absence of L. reuteri has been causally linked to maternal diet. A gut ...https://en.wikipedia.org/wiki/Lactobacillus_reuteri
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... observed in CVID patients is associated with bacterial translocation and that IVIG treatment resolves bacterial translocation ... Finally, we also focus on observations that high-avidity T-cells show higher signs of exhaustion and facilitate the emergence ... suggesting that CD4 T cell dysfunction might be caused by bacterial translocation. Of note, endotoxemia was associated with ... High-avidity HIV-specific CD8 T cells expressed lower levels of CD27 and CD28 and were enriched in cells with an exhausted ...https://www.jove.com/visualize?author=Matthieu+Perreau
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... bacterial translocation and infectious complications up to sepsis and multi organ failure and causes a high economic burden.6 ... Weight gain resumed after 72 hr post DNBS, and by 5 days post DNBS, the FO group had a higher body weight than SO or CO groups ... Therefore the C. rodentium model of enteric bacterial infection serves as a valuable tool to aid in our understanding of these ... We also show that microgavage can permit loading of the intestinal lumen with high concentrations of materials that are lethal ...https://www.jove.com/visualize/abstract/24926782/usefulness-intestinal-fatty-acid-binding-protein-predicting
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... bacterial translocation and infectious complications up to sepsis and multi organ failure and causes a high economic burden.6 ... Infection, Issue 92, Bacterial infection, neonatal bacterial meningitis, bacteremia, sepsis, animal model, K1 polysaccharide, ... RBEC expressed high levels of tight junction (TJ) proteins such as occludin, claudin-5 and ZO-1 with a typical localization at ... Weight gain resumed after 72 hr post DNBS, and by 5 days post DNBS, the FO group had a higher body weight than SO or CO groups ...https://www.jove.com/visualize/abstract/22496907/gastrointestinal-sparing-effects-novel-nsaids-rats-with-compromised