*  Giant-cell tumor of bone - Wikipedia
Giant-cell tumors are normally benign, with unpredictable behavior. It is a heterogeneous tumor composed of three different ... A number of tumors have giant cells, but are not true benign giant-cell tumors. These include, aneurysmal bone cyst, ... of giant-cell tumors metastasize, usually to a lung, which may be benign metastasis, when the diagnosis of giant-cell tumor is ... Giant-cell tumor of the bone accounts for 4-5% of primary bone tumors and about 20% of benign bone tumors. However, ...
  https://en.wikipedia.org/wiki/Giant-cell_tumor_of_bone
*  JCI - Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt
D) Rictor-silenced tumors were morphologically different from controls, as they contained only rare giant and/or large cells, ... IHC for pS6 showed heterogeneous signal with only a few cells being faintly positive. pAktT308-IR, pAktS473-IR, and pNDRG1-IR ... Overall, the lesions forming in P15-17 and P24-26 TPN mice showed benign tumor-like features, such as enlarged cellular mass, ... Indeed, in addition to the 2 populations of small and giant cells observed in P15-17 TPN lesions, a third cell population made ...
  https://www.jci.org/articles/view/96342
*  Benign Osteoblastoma of the Sphenoid Bone
... giant cell tumor, aneurysmal bone cyst, and fibrous dysplasia.13. Definitive diagnosis is made by histological examination that ... Magnetic resonance imaging showing (A) a sagittal T1-weighted image, (B) an axial T2-weighted image with a heterogeneous mass, ... 4 Benign osteoblastoma is a rare tumor that constitutes ~1% of all primary bone tumors and 3% of all benign bone tumors.5 ... Osteoblastoma is an uncommon benign bone tumor that accounts for 1% of all primary bone tumors. Well documented in the spine ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2793891/
*  Rare case of benign epidermal inclusion cyst mimicking malignancy
Lee Y, Park S. Giant sized epidermal inclusion cyst of the breast initially mimicking a large fibroadenoma or phyllodes tumor. ... Squamous cell carcinoma in an epidermal inclusion cyst: Case report. Otolaryngol Head Neck Surg. 2003, 29: 141-143. ... Ultrasound imaging of the breast typically shows an onion ring pattern or heterogeneous hyperechoic and thus solid echo texture ... Rare case of benign epidermal inclusion cyst mimicking malignancy. By Caitlin Martin, MS; Tatyana Bombard, DO; Melinda Coker, ...
  http://appliedradiology.com/articles/rare-case-of-benign-epidermal-inclusion-cyst-mimicking-malignancy
*  Clinical Orthopaedics and Related Research ®
Iterative Curettage is Associated with Local Control in Giant Cell Tumors Involving the Distal Tibia Saleh A. AlSulaimani MBBS ... Benign lesions in the proximal femur can cause pathologic fractures. To avoid fracture, benign tumors and tumor-like lesions in ... Soft tissue sarcomas are a heterogeneous group of malignant tumors. Standard treatment for soft tissue sarcoma of the extremity ... The distal tibia is an unusual location for a giant cell tumor (GCT). Treatment choices are unclear because of their rarity, ...
  http://clinorthop.org/subspecialties/Tumor?page=14
*  Spindle Cell Carcinoma of the Tongue: A Rare Tumor in an Unusual Location
Bizarre cells, multinucleated giant cells, and frequent mitotic figures, some of which were atypical, were also observed in ... The spindle cell component may resemble many lesions, ranging from benign reactive ones like radiation-induced granulation ... The cut surfaces of resected specimen had heterogenous appearance and were firm and whitish in color (Figure 1(c)). Main ... H&E, ×200). (c) "Transition zone of the tumor", spindle-shaped tumor cells "dropping off" from squamous cell carcinoma. (H&E, × ...
  https://www.hindawi.com/journals/pri/2011/572381/
*  Biology of Bone Sarcomas and New Therapeutic Developments | Springer for Research & Development
Bone sarcomas are tumours belonging to the family of mesenchymal tumours and constitute a highly heterogeneous tumour group. ... Giant cell tumours of bone: a benign entity with malignant features. Giant cell tumours of bone are composed of three main cell ... However, the tumour microenvironment of bone sarcomas is also very heterogeneous and includes numerous cell types, all of them ... Giant Cell Tumours of Bone: Benign Tumours with Malignant-Like Properties. In the field of bone sarcoma, giant cell tumours ( ...
  https://rd.springer.com/article/10.1007/s00223-017-0372-2
*  Chondromyxoid fibroma - Wikipedia
Occasional osteoclast-like giant multinucleated cells are encountered particularly at the periphery. Most cells are ... They are benign lesions and malignant degeneration is rare. They are usually treated with curettage which however have a high ... The tumor comprises a variable combination on chondroid, myxoid, and fibrous tissue components organized in a pseudolobulated ... diffuse contrast enhancement and this can be either homogeneous or heterogeneous 19 T2 - high signal Bone scan A scintigraphic ...
  https://en.wikipedia.org/wiki/Chondromyxoid_fibroma
*  Tumor necrosis factor (TNF) | definition of tumor necrosis factor (TNF) by Medical dictionary
What is tumor necrosis factor (TNF)? Meaning of tumor necrosis factor (TNF) medical term. What does tumor necrosis factor (TNF ... Looking for online definition of tumor necrosis factor (TNF) in the Medical Dictionary? tumor necrosis factor (TNF) explanation ... giant cell tumor 1. a benign or malignant tumor containing giant cells; see under carcinoma, granuloma, and sarcoma. ... organoid tumor teratoma.. peripheral neuroectodermal tumor (PNET) any of a heterogeneous group of neoplasms originating in ...
  https://medical-dictionary.thefreedictionary.com/tumor+necrosis+factor+
*  Radiation Oncology/Sarcoma/Overview - Wikibooks, open books for an open world
Synovial Tumors[edit]. *Nodular Tenosynovitis: Giant cell tumor, commonly seen in women, age 30-50. Frequently in hand, but ... Desmoplastic small cell tumor. *Comment: MFH is the most heterogenous group of sarcomas. A hypothesis proposes that MFH, as a ... Adipose Tumors[edit]. *Lipoma: most common benign soft tissue neoplasm. Subcutaneous tissues of trunk and proximal limbs ( ... 1) Malignant Glomus Tumor; 2) Malignant hemangiopericytoma. Synovial. 1) Synovial sarcoma; 2) Malignant giant cell tumor of ...
  https://en.wikibooks.org/wiki/Radiation_Oncology/Soft_tissue_sarcoma
*  Glossary
... cells themselves. Tumor laterality: The preference in location of tumor in one portion of the body over other locations in the ... non-Hodgkin's lymphoma: A heterogeneous group of malignant lymphomas,the only common feature being an absence of the giant Reed ... Meningioma: A benign, slow-growing tumour of the meninges, usually next to the dura mater. ... These cells produce male hormones, especially testosterone. Lymphocyte: The white blood cell found in the blood, lymph, and ...
  http://rfcom.ca/glossary/index.shtml
*  Giant Cell Reparative Granuloma of the Nasal Cavity | American Journal of Neuroradiology
Pathologically, the differential diagnoses for giant cell lesions in bone include giant cell tumor, brown tumor of ... In 1953, Jaffe (1) first described giant cell reparative granuloma (GCRG) as a benign lesion affecting the mandible and maxilla ... On CT scans, they appear as heterogeneous soft tissue masses with occasional hemorrhagic or cystic foci (7, 8), as our case did ... From the archives of AFIP: imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic ...
  http://www.ajnr.org/content/25/7/1263
*  Nephroblastomas | definition of nephroblastomas by Medical dictionary
giant cell tumor 1. a benign or malignant tumor containing giant cells; see under carcinoma, granuloma, and sarcoma. ... organoid tumor teratoma.. peripheral neuroectodermal tumor (PNET) any of a heterogeneous group of neoplasms originating in ... Hürthle cell tumor see hürthle cell tumor.. islet cell tumor a tumor of the islands of Langerhans; many secrete excessive ... Krukenberg's tumor see krukenberg's tumor.. lipoid cell tumor of ovary a usually benign ovarian tumor composed of eosinophilic ...
  https://medical-dictionary.thefreedictionary.com/nephroblastomas
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
RasV12 and loss of cell polarity genes (scribbled, discs large and lethal giant larvae) to generate invasive tumors 9. I ... Medicine, Issue 79, Imaginal Discs, Drosophila melanogaster, Neoplasm Metastasis, Drosophila, Invasive Tumors, Benign Tumors, ... Malignant gliomas constitute a heterogeneous group of highly infiltrative glial neoplasms with distinct clinical and molecular ... Single-cell tracking is used to generate cell fate maps for measurement of individual cell lifetimes and investigation of cell ...
  https://www.jove.com/visualize/abstract/22792303/loss-of-brca1-a-complex-function-in-rap80-null-tumor-cells
*  Current Concepts and Occurrence of Epithelial Odontogenic Tumors: II. Calcifying Epithelial Odontogenic Tumor Versus Ghost Cell...
The existence of benign odontogenic tumor-associated CCOT implies CCOT's heterogeneous nature. Hybrid odontogenic tumors can ... Nuclei show considerable variation, and giant nuclei may be seen. Some tumors show considerable nuclear pleomorphism, but this ... Odontogenic ghost cell tumour with clear cell components: clear cell odontogenic ghost cell tumour? J Oral Pathol Med 2004; 33 ... ghost cell odontogenic tumor; CCOT, calcifying cystic odontogenic tumor; DGCT, dentinogenic ghost cell tumor; GCOC, ghost cell ...
  http://jpatholtm.org/journal/view.php?number=3259
*  EURORAD - Radiologic Teaching Files
Primary benign tumours are giant cell tumour, aneurysmal bone cyst, osteoid osteoma, osteoblastoma, osteochondroma/exostosis, ... Sagittal T2-weighted MR image reveals a heterogeneous hyperintense tumour in the sacral region, extending from the skin, ... Post-contrast axial T1-weighted MR image reveals heterogeneous enhancement of tumour involving sacral bone from S2 segment, ... Sagittal T2-weighted MR image reveals a heterogeneous hyperintense tumour in the sacral region, extending from the skin, ...
  http://www.eurorad.org/eurorad/case.php?id=8554&lang=en
*  Chondroma | Article about Chondroma by The Free Dictionary
a benign tumor of mature cartilage tissue.... Explanation of Chondroma ... A benign tumor of bone, cartilage, or other tissue which simulates the structure of cartilage in its growth. ... The differential diagnosis includes ossifying hematoma, branchial cyst, adenopathy, preauricular cyst, giant-cell tumor, ... Intracapsular chondroma appears as a heterogeneous mass on MRI.. Function of the infrapatellar fat pad and advanced Hoffa's ...
  http://encyclopedia2.thefreedictionary.com/Chondroma
*  Surgical treatment of giant plexiform neurofibroma associated with pectus excavatum | Journal of Cardiothoracic Surgery | Full...
Plexiform neurofibromas (PNFs) are benign nerve tumor resulting from aberrant growth of the cells of nerve sheath. They are ... Computer tomographic scan showed a well-defined heterogeneous soft tissue density tumor without signs of erosion of the rib and ... But there is no denying the fact that the resection of a giant benign tumor can be important in minimizing cosmetics ... clinical alone do not allow differentiation of malignant tumors and benign PNF. Such tumors should be further examined with CT ...
  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-6-119
*  Adrenal Myelolipoma Imaging: Overview, Radiography, Computed Tomography
Adrenal myelolipoma is a rare benign neoplasm composed of mature adipose tissue and a variable amount of hematopoietic elements ... If the tumor contains a predominance of myeloid cells, it may appear heterogeneous or hypoechoic. [29, 30] ... characteristics suggesting benign adenoma were indeed benign lesions and included 61 benign adrenal adenomas and 5 benign ... Giant adrenal myelolipoma with minimal fat content in a patient with homozygous beta-thalassemia: appearance on MRI. J Magn ...
  https://emedicine.medscape.com/article/376700-overview
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
RasV12 and loss of cell polarity genes (scribbled, discs large and lethal giant larvae) to generate invasive tumors 9. I ... Medicine, Issue 79, Imaginal Discs, Drosophila melanogaster, Neoplasm Metastasis, Drosophila, Invasive Tumors, Benign Tumors, ... MDSC are a heterogeneous population of immature macrophages, dendritic cells and granulocytes that accumulate in lymphoid ... imaging of T-cell interaction with tumor cells and tumor cells migration along the collagen IV of basement membrane. Taken ...
  https://www.jove.com/visualize/abstract/19557135/a-systems-immunology-approach-to-host-tumor-interaction-large-scale
*  MRI Evaluation of masses in the noncirrhotic liver
Benign masses. Hemangioma. Hemangioma is the most common benign hepatic tumor. The prevalence of hemangioma in the general ... Hypervascular metastases are seen with neuroendocrine tumors, renal cell carcinoma, thyroid carcinoma, melanoma, and sarcoma. ... Giant cavernous hemangioma of the liver: CT and MR imaging in 10 cases. AJR Am J Roentgenol. 1989;152:1221-1226. ... On dynamic contrast-enhanced images, adenomas show heterogeneous hypervascularity during the arterial phase (Figure 3C). These ...
  http://appliedradiology.com/articles/mri-evaluation-of-masses-in-the-noncirrhotic-liver
*  Leiomyosarcoma with Unusual Macroscopic Features: A Case Report
The fundus of the uterus was ruptured by the solid part of the tumor. For treatment, total hysterectomy, salpingo-oophorectomy ... biological behavior and poor overall survival of uterine sarcoma challenge the post-operative management of this tumor. ... Uterine sarcoma is a rare tumor of mesodermal origin, accounting for 2-6% of uterine malignancies. Leiomyosarcoma (LMS) has ... As the cellularity increases, nuclear atypia increases, cytoplasm becomes more eosinophilic and the number of giant cells rises ...
  http://jmrh.mums.ac.ir/article_4433.html
*  Unusual cancers of the pancreas | ПРЕЦИЗИОННАЯ ОНКОЛОГИЯ
Tumors of the pancreas collectively are the fourth leading cause of neoplastic death despite being only the 10th most common ... Circulating tumor cells *Significance of studying circulating tumor cells. *Affinity-based enrichment of circulating tumor ... Undifferentiated carcinoma with osteoclast-like giant cells. Undifferentiated carcinomas with osteoclast-like giant cells are a ... Rare, nonendocrine tumors of the pancreas are heterogeneous in origin, presentation, and prognosis. Many of these rare tumors ...
  http://cancerlink.ru/pancreatic-tumors-en/unusual-cancers-pancreas/
*  USP6 | Cancer Genetics Web
2 brown tumors, or 8 giant cell tumors of bone. Of the 22 primary ABCs, 13 (59%) showed USP6 gene rearrangements. In conclusion ... Fusion of the COL1A1 and USP6 genes in a benign bone tumor.. Cancer Genet Cytogenet. 2008; 180(1):70-3 [PubMed] Related ... Heterogeneous transforming growth factor (TGF)-beta unresponsiveness and loss of TGF-beta receptor type II expression caused by ... 8 giant cell tumors of bone, and 2 brown tumors of hyperparathyroidism. Overall, there were 49 samples from 48 patients ...
  http://www.cancerindex.org/geneweb/USP6.htm
*  Most recent papers with the keyword Castleman | Read by QxMD
... giant cell arteritis as well as for the treatment of chimeric antigen receptor T cell therapy-induced cytokine release syndrome ... Robotic resection of benign nonadrenal retroperitoneal tumors: A consecutive case series.. Qu Liu, Yuanxing Gao, Zhiming Zhao, ... IgG4-related disease is a heterogeneous immune-mediated fibroinflammatory condition that can affect every single organ. This ... This study aimed to evaluate the safety and feasibility of robotic resection of benign nonadrenal retroperitoneal tumors. ...
  https://www.readbyqxmd.com/keyword/20754