Loading...
*  Desmoplastic small-round-cell tumor - Wikipedia
Other treatment options include: hematopoietic stem cell transplantation, intensity-modulated radiation Therapy, radiofrequency ... In dogs, mast cell tumors are the most frequent round cell tumor. There are few early warning signs that a patient has a DSRCT ... DSRCT shares characteristics with other small-round blue cell cancers including Ewing's sarcoma, acute leukemia, small cell ... Small Round Cell Tumor in the Sarcoma Learning Center Desmoplastic Small Round Cell Tumor Desmoplastic Small Round Blue Cell ...
  https://en.wikipedia.org/wiki/Desmoplastic_small-round-cell_tumor
*  Blood and Lymph Unit 3 Flashcards by Kristen Stahl | Brainscape
clonal hematopoietic stem cell disorder associated with BCR-ABL1 gene fusion, prominent neutrophilic leukocytosis. blood cell ... Mast cells' FceR are loaded then with anti-helminth IgE. -antigen cross links IgE and mast cells degranulate. -histamine causes ... extramedullary myeloid tumor (granulocytic sarcoma): malignancy of hematopoietic cells, from myeloid cells or precursors ( ... malignancy of hematopoietic cells, involvement of blood/marrow. myelogenic cells. -lymphoma: malignancy of hematopoietic cells ...
  https://www.brainscape.com/flashcards/blood-and-lymph-unit-3-4806757/packs/6999439
*  Intestinal Stromal Tumors: Background, Pathophysiology, Epidemiology
... mesenchymal tumors were considered smooth muscle sarcomas (leiomyosarcomas). Unlike leiomyosarcomas, however, GI mesenchymal ... KIT receptor is expressed in mast cells, melanocytes, Leydig cells, hematopoietic stem cells, cutaneous basal cells, and breast ... Sarcoma of the stomach: clinicopathologic study of 43 cases. J Surg Oncol. 1980. 13(2):121-7. [Medline]. ... systemic mast cell disease, urticaria, and spindle cell hyperplasia of the GI tract. They all carry a germline mutation of the ...
  https://emedicine.medscape.com/article/284127-overview
*  Recombinant human c-Kit (mutated N822 K) protein (Active) (ab184879)
Ab184879 is an active protein fragment produced in Baculovirus infected Sf9 cells and has… ... stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG ... Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. ... v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog. *v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like ...
  https://www.abcam.com/recombinant-human-c-kit-mutated-n822-k-protein-active-ab184879.html
*  Recombinant Human c-Kit protein (ab158795) | Abcam
... stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG ... Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. ... v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog. *v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like ... Cell Biology. Epigenetics. Metabolism. Developmental Biology. By research area. Immunology. Microbiology. Neuroscience. Signal ...
  http://www.abcam.com/recombinant-human-c-kit-protein-ab158795.html
*  CD117 - Wikipedia
Mobilization is used clinically as a source of hematopoietic stem cells for hematopoietic stem cell transplantation (HSCT). ... It is also a marker for mouse prostate stem cells. In addition, mast cells, melanocytes in the skin, and interstitial cells of ... KIT was first described by the German biochemist Axel Ullrich in 1987 as the cellular homolog of the feline sarcoma viral ... CD117 is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. Altered forms of ...
  https://en.wikipedia.org/wiki/CD117
*  Dr. Poonkuzhali Balasubramanian - Department of Haematology
Mast cell sarcoma of the small intestine: a case report. Bugalia A, Abraham A, Balasubramanian P, Srivastava A, Nair S. J Clin ... Personalizing conditioning regimen in hematopoietic stem cell transplantation. Another major area of research in our laboratory ... Personalizing conditioning regimen in hematopoietic stem cell transplantation. Wellcome DBT. 445. Oct 2015 -2020. ... application for routine therapeutic monitoring in haematopoietic stem cell transplantation. Desire S, Mohanan EP, George B, ...
  http://cmchaematology.org/dr-poonkuzhali-balasubramanian.php
*  Mast cell - Wikipedia
Other neoplastic disorders associated with mast cells include mast cell sarcoma and mast cell leukemia. Mast cell activation ... and biomarkers of mast cell degranulation. Unlike other hematopoietic cells of the immune system, mast cells naturally occur in ... "Distinguishing mast cell and granulocyte differentiation at the single-cell level". Cell Stem Cell. 6: 361-8. doi:10.1016/j. ... connective tissue-type mast cells and mucosal mast cells. The activities of the latter are dependent on T-cells. Mast cells are ...
  https://en.wikipedia.org/wiki/Mast_cell
*  World Allergy Organization
Cladribne is a nucleoside analogue and is a non-specific poison of mast cells as well as other hematopoietic cells. It usually ... The growth , differentiation and survival of mast cells depends on stem cell factor (SCF) which binds KIT (CD117), a receptor ... Mast cell sarcoma: This is a rare solid tumor with invasive features and malignant spread and carries a poor prognosis. ... Aberrant cytomorphology of the mast cells. Normal mast cells are round and fully granulated with a central nucleus. Mast cells ...
  http://www.worldallergy.org/professional/allergic_diseases_center/mastocytosis/
*  Department News | UC Davis Health System Department of Pathology
"Autologous Graft vs Host Disease Involving the Gastrointestinal Tract Following Hematopoietic Stem Cell Transplantation." Co- ... Amini's poster was "Mast Cell Rich Leiomyoma as a Mimic of Gastrointestinal Stromal Tumor." ... Wei presented two posters: "Primary Undifferentiated Pleomorphic Sarcoma of Spleen: A Rare Localization and Review of the ... Faculty member Leonor Fernando and colleagues presented a poster on the effects of ABO mismatch on stem cell transplants at the ...
  https://www.ucdmc.ucdavis.edu/pathology/news/index.html
*  Mastocytosis (Urticaria Pigmentosa, Telangiectasia Macularis Eruptiva Perstans)
KIT is expressed on mast cells, melanocytes, primitive hematopoietic stem cells, primordial germ cells, and interstitial cells ... Mast cell sarcomas and extracutaneous mastocytomas are extremely rare. Sarcomas containing poorly differentiated mast cells ... Mast cell leukemia is rare.. The diagnosis of mast cell leukemia requires the peripheral blood nucleated cell population to be ... mast cell leukemia (MCL), mast cell sarcoma and extracutaneous mastocytomas.. Patients with CM represent the largest group and ...
  https://www.neurologyadvisor.com/dermatology/mastocytosis-urticaria-pigmentosa-telangiectasia-macularis-eruptiva-perstans/article/589744/
*  Serum c-kit Protein Detection as a Reliable Biomarker for the Diagnosis of Gastrointestinal Stromal Tumors: A Case-Control...
... gastrointestinal tract pacemaker cells (Cajal cells), hematopoietic stem cells, cutaneous basal cells, Leydig cells, ... Preferential localization of c-kit product in tissue mast cells, basal cells of skin, epithelial cells of breast, small cell ... Corless CL, Heinrich MC (2008) Molecular pathobiology of gastrointestinal stromal sarcomas. Annu Rev Pathol 3: 557-586. ... Furthermore, soluble c-Kit shed from mast cells and other KIT-bearing hematopoietic cells might be expected to increase in case ...
  https://www.omicsonline.org/open-access/serum-ckit-protein-detection-as-a-reliable-biomarker-for-the-diagnosis-of-gastrointestinal-stromal-tumors-a-casecontrol-study-2155-9929.S6-001.php?aid=28754
*  Phospho anti-VEGF Receptor 2 (Y1054 + Y1059) antibody (ab5473) | Abcam
... rapid neonatal growth for up to 12 months characterized by endothelial hypercellularity and increased numbers of mast cells. ... the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. ... Stem Cells. *Hematopoietic Progenitors. *Surface Molecules. *Cancer. *Growth factors. *VEGF. *Cancer. *Invasion/ ... Lane 1 : Human umbilical vein endothelial cells with Skimmed milk. Lane 2 : Human umbilical vein endothelial cells treated with ...
  https://www.abcam.com/VEGF-Receptor-2-phospho-Y1054--Y1059-antibody-ab5473.html
*  004847 - B6;129-Gt(ROSA)26Sor|tm1(cre/ERT)Nat|/J
p53-mediated hematopoietic stem and progenitor cell competition. Cell Stem Cell 6(4):309-22. PubMed: 20362536MGI: J:158953 ... PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular ... A CreER-based random induction strategy for modeling translocation-associated sarcomas in mice. Cancer Res 69(8):3657-64. ... TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms. PLoS One 7(11): ...
  https://www.jax.org/strain/004847
*  Phospho anti-c-Kit (Y823) antibody (ab5634) | Abcam
Mast Cell Lineage. *Stem Cells. *Hematopoietic Progenitors. *Hematopoietic Stem Cells. *HSC markers ... v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody. *v kit Hardy Zuckerman 4 feline sarcoma viral oncogene ... stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG ... Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. ...
  http://www.abcam.com/c-Kit-phospho-Y823-antibody-ab5634.html
*  Overview & Diagnosis - TMS - The Mastocytosis Society :TMS - The Mastocytosis Society
Horny HP, Sotlar K, Valent P, Hartmann K. Mastocytosis: a disease of the hematopoietic stem cell. Dtsch Arztebl Int. 2008 Oct; ... and mast cell sarcoma these diseases occur in both children and adults. CM is considered a benign skin disease representing the ... with mast cells that are functioning normally, and someone with a mast cell disorder, whose mast cells may be activating ... 2 The two major forms of mast cell disorders are mastocytosis and mast cell activation syndromes (MCAS). Mast cell disorders ...
  https://tmsforacure.org/overview/
*  CD34 - Wikipedia
It is important to mention that Long-Term Hematopoietic Stem Cells (LT-HSCs) in mice and humans are the hematopoietic cells ... endothelial cells of blood vessels but not lymphatics (except pleural lymphatics), mast cells, a sub-population dendritic cells ... giant cell fibroblastoma, granulocytic sarcoma, Kaposi's sarcoma, liposarcoma, malignant fibrous histiocytoma, malignant ... in a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells ...
  https://en.wikipedia.org/wiki/CD34
*  Injection-Site Sarcoma in a Dog: Clinical and Pathological Findings
Stem Cell Factor (SCF), and Epithelial Growth Factor Receptor (EGFR) and negative for VEGF, PDGR, KIT, and p-53. ... sarcomas, and hematopoietic neoplasms. Partial responses and stable disease are more commonly observed than complete responses ... that is licensed for use in the US and Europe at the maximally tolerated label dose of 3.25 mg/kg for high-grade mast cell ... Injection-site sarcomas commonly occur in cats but are rare in other species [1, 2]. Most injection-site sarcomas occur at the ...
  https://www.hindawi.com/journals/crivem/2017/6952634/
*  CD117/c-kit Antibody (kit2c75) [Alexa Fluor® 647] (NBP1-28327AF647): Novus Biologicals
Hematopoietic Stem Cell Marker. Validated: Flow, ICC/IF. Tested Reactivity: Chicken. 100% Guaranteed. ... v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog. *v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like ... Hematopoietic Stem Cell Markers. *Immunology. *Innate Immunity. *Mast Cell Markers. *Mesenchymal Stem Cell Markers ... Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA) ...
  https://www.novusbio.com/products/cd117-c-kit-antibody-kit2c75_nbp1-28327af647
*  Mast cell growth factor | definition of mast cell growth factor by Medical dictionary
What is mast cell growth factor? Meaning of mast cell growth factor medical term. What does mast cell growth factor mean? ... Looking for online definition of mast cell growth factor in the Medical Dictionary? mast cell growth factor explanation free. ... including endothelial cells, fat cells, embryonic stem cells, germ cells, osteoblasts, and peripheral nerve cells. ... hematopoietic growth factor. Any of a group of at least seventeen substances involved in the production of blood cells, ...
  http://medical-dictionary.thefreedictionary.com/mast+cell+growth+factor
*  Clonal hypereosinophilia - Wikipedia
Hematopoietic stem cells give rise to: 1) myeloid precursor cells that differentiate into red blood cells, mast cells, blood ... myeloid sarcoma, lymphoid leukemia, or non-Hodgkin lymphomas. Based on their association with eosinophils, unique genetic ... it is critical for the normal cell cycle and cell division (see PCM1). Acquired mutations in early hematopoietic stem cells ... B-cell lymphoma, T-cell lymphomas, T cell leukemias, and Langerhans cell histiocytosis. Other hematological diseases are ...
  https://en.wikipedia.org/wiki/Clonal_hypereosinophilia
*  European Mastocytosis Support Network | Sweden
There are two different and very rare solid mast cell tumours. Mast Cell Sarcoma, which is malignant and Extracutaneous ... Mastocytosis: an unusual clonal disorder of bone marrow-derived hematopoietic progenitor cells. Am J Clin Pathol. 2009 Sep;132( ... radiation or stem cell transplant may be necessary. Literature. European Competence Network on Mastocytosis. Information On ... mast cell infiltrate (, 15 mast cells) or scattered mast cells (, 20 mast cells) ...
  http://www.mastocytosis.eu/countries/sweden.php
*  prof. dr. E. (Erik) Teske - Diergeneeskunde - Universiteit Utrecht
Teske, E. & Rutteman, G.R. (14-04-2005). Management of mast cell tumours: an update. Scientific Proceedings Voorjaarsdagen 2005 ... Efficay and toleranility of monotherapy with masitinib for canine epitheliotropic T-cell lymphoma and histiocytic sarcoma. ... "studies are oriented at the role of cancer stem cells in mammary, adrenal and insulin-producing carcinomas. ... E. Teske (23-09-2007) Paraneoplastic syndromes, including hematopoietic E. Teske (23-09-2007) Plasma cell neoplasia ...
  https://www.uu.nl/medewerkers/ETeske
*  Adult T-cell leukemia/lymphoma | definition of Adult T-cell leukemia/lymphoma by Medical dictionary
What is Adult T-cell leukemia/lymphoma? Meaning of Adult T-cell leukemia/lymphoma medical term. What does Adult T-cell leukemia ... Looking for online definition of Adult T-cell leukemia/lymphoma in the Medical Dictionary? Adult T-cell leukemia/lymphoma ... Called also stem cell leukemia and undifferentiated cell leukemia.. adult T-cell leukemia (adult T-cell leukemia/lymphoma) a ... B-cell type) acute lymphoblastic l.. mast cell leukemia a rare form marked by overwhelming numbers of tissue mast cells in the ...
  https://medical-dictionary.thefreedictionary.com/Adult+T-cell+leukemia%2Flymphoma
*  ICD-10 Chapter II: Neoplasms - Wikipedia
... haematopoietic and related tissue (D47.0) Histiocytic and mast cell tumours of uncertain and unknown behaviour Mast cell tumour ... Myeloid sarcoma Chloroma Granulocytic sarcoma (C92.4) Acute promyelocytic leukemia (C92.5) Acute myelomonocytic leukemia (C93) ... Brain stem (C71.8) Overlapping lesion of brain (C71.9) Brain, unspecified (C72) Malignant neoplasm of spinal cord, cranial ... small cell (diffuse) (C83.1) Small cleaved cell (diffuse) (C83.2) Mixed small and large cell (diffuse) (C83.3) large cell ( ...
  https://en.wikipedia.org/wiki/ICD-10_Chapter_II:_Neoplasms