*  Desmoplastic small-round-cell tumor - Wikipedia
Other treatment options include: hematopoietic stem cell transplantation, intensity-modulated radiation Therapy, radiofrequency ... In dogs, mast cell tumors are the most frequent round cell tumor. There are few early warning signs that a patient has a DSRCT ... DSRCT shares characteristics with other small-round blue cell cancers including Ewing's sarcoma, acute leukemia, small cell ... Small Round Cell Tumor in the Sarcoma Learning Center Desmoplastic Small Round Cell Tumor Desmoplastic Small Round Blue Cell ...
  https://en.wikipedia.org/wiki/Desmoplastic_small-round-cell_tumor
*  Intestinal Stromal Tumors: Background, Pathophysiology, Epidemiology
... mesenchymal tumors were considered smooth muscle sarcomas (leiomyosarcomas). Unlike leiomyosarcomas, however, GI mesenchymal ... KIT receptor is expressed in mast cells, melanocytes, Leydig cells, hematopoietic stem cells, cutaneous basal cells, and breast ... Sarcoma of the stomach: clinicopathologic study of 43 cases. J Surg Oncol. 1980. 13(2):121-7. [Medline]. ... systemic mast cell disease, urticaria, and spindle cell hyperplasia of the GI tract. They all carry a germline mutation of the ...
  https://emedicine.medscape.com/article/284127-overview
*  Recombinant Human c-Kit protein (ab158795) | Abcam
... stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG ... Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. ... v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog. *v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like ... Cell Biology. Epigenetics. Metabolism. Developmental Biology. By research area. Immunology. Microbiology. Neuroscience. Signal ...
  http://www.abcam.com/recombinant-human-c-kit-protein-ab158795.html
*  CD117 - Wikipedia
Mobilization is used clinically as a source of hematopoietic stem cells for hematopoietic stem cell transplantation (HSCT). ... It is also a marker for mouse prostate stem cells. In addition, mast cells, melanocytes in the skin, and interstitial cells of ... KIT was first described by the German biochemist Axel Ullrich in 1987 as the cellular homolog of the feline sarcoma viral ... CD117 is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. Altered forms of ...
  https://en.wikipedia.org/wiki/CD117
*  Dr. Poonkuzhali Balasubramanian - Department of Haematology
Mast cell sarcoma of the small intestine: a case report. Bugalia A, Abraham A, Balasubramanian P, Srivastava A, Nair S. J Clin ... Personalizing conditioning regimen in hematopoietic stem cell transplantation. Another major area of research in our laboratory ... Personalizing conditioning regimen in hematopoietic stem cell transplantation. Wellcome DBT. 445. Oct 2015 -2020. ... application for routine therapeutic monitoring in haematopoietic stem cell transplantation. Desire S, Mohanan EP, George B, ...
  http://cmchaematology.org/dr-poonkuzhali-balasubramanian.php
*  World Allergy Organization
Cladribne is a nucleoside analogue and is a non-specific poison of mast cells as well as other hematopoietic cells. It usually ... The growth , differentiation and survival of mast cells depends on stem cell factor (SCF) which binds KIT (CD117), a receptor ... Mast cell sarcoma: This is a rare solid tumor with invasive features and malignant spread and carries a poor prognosis. ... Aberrant cytomorphology of the mast cells. Normal mast cells are round and fully granulated with a central nucleus. Mast cells ...
  http://www.worldallergy.org/professional/allergic_diseases_center/mastocytosis/
*  Mast cell - Wikipedia
Other neoplastic disorders associated with mast cells include mast cell sarcoma and mast cell leukemia. Mast cell activation ... and biomarkers of mast cell degranulation. Unlike other hematopoietic cells of the immune system, mast cells naturally occur in ... "Distinguishing mast cell and granulocyte differentiation at the single-cell level". Cell Stem Cell. 6: 361-8. doi:10.1016/j. ... connective tissue-type mast cells and mucosal mast cells. The activities of the latter are dependent on T-cells. Mast cells are ...
  https://en.wikipedia.org/wiki/Mast_cell
*  Department News | UC Davis Health System Department of Pathology
"Autologous Graft vs Host Disease Involving the Gastrointestinal Tract Following Hematopoietic Stem Cell Transplantation." Co- ... Amini's poster was "Mast Cell Rich Leiomyoma as a Mimic of Gastrointestinal Stromal Tumor." ... Wei presented two posters: "Primary Undifferentiated Pleomorphic Sarcoma of Spleen: A Rare Localization and Review of the ... Faculty member Leonor Fernando and colleagues presented a poster on the effects of ABO mismatch on stem cell transplants at the ...
  https://www.ucdmc.ucdavis.edu/pathology/news/index.html
*  Frontiers | Low-Intensity Ultrasound-Induced Anti-inflammatory Effects Are Mediated by Several New Mechanisms Including Gene...
... myeloid-derived suppressor cells), MSCs (mesenchymal stem cells), B1-B cells and Treg (regulatory T cells); 3) LIUS not only ... myeloid-derived suppressor cells), MSCs (mesenchymal stem cells), B1-B cells and Treg (regulatory T cells); 3) LIUS not only ... but also can make use of natural membrane vesicles as small as exosomes derived from immunosuppressor cells as a novel ... but also can make use of natural membrane vesicles as small as exosomes derived from immunosuppressor cells as a novel ...
  https://www.frontiersin.org/articles/10.3389/fphys.2017.00818/full
*  004847 - B6;129-Gt(ROSA)26Sor|tm1(cre/ERT)Nat|/J
p53-mediated hematopoietic stem and progenitor cell competition. Cell Stem Cell 6(4):309-22. PubMed: 20362536MGI: J:158953 ... PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular ... A CreER-based random induction strategy for modeling translocation-associated sarcomas in mice. Cancer Res 69(8):3657-64. ... TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms. PLoS One 7(11): ...
  https://www.jax.org/strain/004847
*  Phospho anti-c-Kit (Y823) antibody (ab5634) | Abcam
Mast Cell Lineage. *Stem Cells. *Hematopoietic Progenitors. *Hematopoietic Stem Cells. *HSC markers ... v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody. *v kit Hardy Zuckerman 4 feline sarcoma viral oncogene ... stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG ... Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. ...
  http://www.abcam.com/c-Kit-phospho-Y823-antibody-ab5634.html
*  Overview & Diagnosis - TMS - The Mastocytosis Society :TMS - The Mastocytosis Society
Horny HP, Sotlar K, Valent P, Hartmann K. Mastocytosis: a disease of the hematopoietic stem cell. Dtsch Arztebl Int. 2008 Oct; ... and mast cell sarcoma these diseases occur in both children and adults. CM is considered a benign skin disease representing the ... with mast cells that are functioning normally, and someone with a mast cell disorder, whose mast cells may be activating ... 2 The two major forms of mast cell disorders are mastocytosis and mast cell activation syndromes (MCAS). Mast cell disorders ...
  https://tmsforacure.org/overview/
*  CD117/c-kit Antibody (kit2c75) [Alexa Fluor® 647] (NBP1-28327AF647): Novus Biologicals
Hematopoietic Stem Cell Marker. Validated: Flow, ICC/IF. Tested Reactivity: Chicken. 100% Guaranteed. ... v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog. *v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like ... Hematopoietic Stem Cell Markers. *Immunology. *Innate Immunity. *Mast Cell Markers. *Mesenchymal Stem Cell Markers ... Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA) ...
  https://www.novusbio.com/products/cd117-c-kit-antibody-kit2c75_nbp1-28327af647
*  CD34 - Wikipedia
It is important to mention that Long-Term Hematopoietic Stem Cells (LT-HSCs) in mice and humans are the hematopoietic cells ... endothelial cells of blood vessels but not lymphatics (except pleural lymphatics), mast cells, a sub-population dendritic cells ... giant cell fibroblastoma, granulocytic sarcoma, Kaposi's sarcoma, liposarcoma, malignant fibrous histiocytoma, malignant ... in a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells ...
  https://en.wikipedia.org/wiki/CD34
*  European Mastocytosis Support Network | Sweden
There are two different and very rare solid mast cell tumours. Mast Cell Sarcoma, which is malignant and Extracutaneous ... Mastocytosis: an unusual clonal disorder of bone marrow-derived hematopoietic progenitor cells. Am J Clin Pathol. 2009 Sep;132( ... radiation or stem cell transplant may be necessary. Literature. European Competence Network on Mastocytosis. Information On ... mast cell infiltrate (, 15 mast cells) or scattered mast cells (, 20 mast cells) ...
  http://www.mastocytosis.eu/countries/sweden.php
*  prof. dr. E. (Erik) Teske - Diergeneeskunde - Universiteit Utrecht
Teske, E. & Rutteman, G.R. (14-04-2005). Management of mast cell tumours: an update. Scientific Proceedings Voorjaarsdagen 2005 ... Efficay and toleranility of monotherapy with masitinib for canine epitheliotropic T-cell lymphoma and histiocytic sarcoma. ... "studies are oriented at the role of cancer stem cells in mammary, adrenal and insulin-producing carcinomas. ... E. Teske (23-09-2007) Paraneoplastic syndromes, including hematopoietic E. Teske (23-09-2007) Plasma cell neoplasia ...
  https://www.uu.nl/medewerkers/ETeske
*  Clonal hypereosinophilia - Wikipedia
Hematopoietic stem cells give rise to: 1) myeloid precursor cells that differentiate into red blood cells, mast cells, blood ... myeloid sarcoma, lymphoid leukemia, or non-Hodgkin lymphomas. Based on their association with eosinophils, unique genetic ... it is critical for the normal cell cycle and cell division (see PCM1). Acquired mutations in early hematopoietic stem cells ... B-cell lymphoma, T-cell lymphomas, T cell leukemias, and Langerhans cell histiocytosis. Other hematological diseases are ...
  https://en.wikipedia.org/wiki/Clonal_hypereosinophilia
*  Adult T-cell leukemia/lymphoma | definition of Adult T-cell leukemia/lymphoma by Medical dictionary
What is Adult T-cell leukemia/lymphoma? Meaning of Adult T-cell leukemia/lymphoma medical term. What does Adult T-cell leukemia ... Looking for online definition of Adult T-cell leukemia/lymphoma in the Medical Dictionary? Adult T-cell leukemia/lymphoma ... Called also stem cell leukemia and undifferentiated cell leukemia.. adult T-cell leukemia (adult T-cell leukemia/lymphoma) a ... B-cell type) acute lymphoblastic l.. mast cell leukemia a rare form marked by overwhelming numbers of tissue mast cells in the ...
  https://medical-dictionary.thefreedictionary.com/Adult+T-cell+leukemia%2Flymphoma
*  ICD-10 Chapter II: Neoplasms - Wikipedia
... haematopoietic and related tissue (D47.0) Histiocytic and mast cell tumours of uncertain and unknown behaviour Mast cell tumour ... Myeloid sarcoma Chloroma Granulocytic sarcoma (C92.4) Acute promyelocytic leukemia (C92.5) Acute myelomonocytic leukemia (C93) ... Brain stem (C71.8) Overlapping lesion of brain (C71.9) Brain, unspecified (C72) Malignant neoplasm of spinal cord, cranial ... small cell (diffuse) (C83.1) Small cleaved cell (diffuse) (C83.2) Mixed small and large cell (diffuse) (C83.3) large cell ( ...
  https://en.wikipedia.org/wiki/ICD-10_Chapter_II:_Neoplasms
*  Patent US20030144232 - Expression system - Google Patents
The invention also provides for vectors, cells and non-human transgenic animal comprising the polynucleotides of the invention ... The cell may be a multipotent cell or a differentiated cell. Preferred cells include stem cells such as haematopoietic stem ... sarcoma (for example Ewing, experimental, Kaposi, and mast cell sarcomas). The cancer may be one of the bone, breast, digestive ... mixed cell, null cell, T cell, T-cell chronic, HTLV-II-associated, lymphocytic acute, lymphocytic chronic, mast cell, and ...
  http://www.google.com/patents/US20030144232?dq=patent:5881444
*  Blood Count
... cell lines, and also affect cells outside the hematopoietic system.. hepatocyte growth factor, a potent mitogen and inducer of ... they are also expressed in the cells of small cell lung carcinoma, sarcoma, and neuroblastoma, and antibodies to them are ... differentiation of stem cells into granulocyte and monocyte cell colonies, and were originally named according to their ability ... IgE receptors, membrane receptors for immunoglobulin E (IgE) on mast cells and basophils; the IgE molecules are bound by a site ...
  http://mtresources.tripod.com/Arteries/bloodcount.htm
*  Plus it
KIT is normally expressed by hematopoietic progenitor cells, mast cells, germ cells, interstitial cells of Cajal, and also by ... Stem cell factor induces proliferation and differentiation of highly enriched murine hematopoietic cells. Proc Natl Acad Sci U ... with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma ... The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. ...
  http://clincancerres.aacrjournals.org/content/11/10/3668
*  Acute Myeloid Leukemia
... predicted to be at high risk of relapse based on these factors are generally offered allogeneic hematopoietic stem cell ... Sometimes the signs and symptoms of other "small round blue-cell tumors" of childhood, including Ewing sarcoma, lymphoma, ... and mast cells. GATA-1 mutations confer increased sensitivity to cytarabine, possibly by decreasing cytidine deaminase ... "A review on allogeneic stem cell transplantation for newly diagnosed pediatric acute myeloid leukemia". Blood. vol. 116. 2010. ...
  http://www.psychiatryadvisor.com/pediatrics/acute-myeloid-leukemia/article/620498/
*  Leukemia | definition of leukemia by Medical dictionary
Called also stem cell leukemia and undifferentiated cell leukemia.. adult T-cell leukemia (adult T-cell leukemia/lymphoma) a ... B-cell type) acute lymphoblastic l.. mast cell leukemia a rare form marked by overwhelming numbers of tissue mast cells in the ... n cancer of hematopoeitic tissues common in older men distinguished by proliferation of lymphocytes, especially B cells. ... Massively diffuse multifocal granulocytic sarcoma in a child with acute myeloid leukemia.. Head and neck granulocytic sarcoma ...
  http://medical-dictionary.thefreedictionary.com/leukemia
*  Mediators of Inflammation-Induced Bone Damage in Arthritis and Their Control by Herbal Products
Osteoclasts are large multinuclear cells derived from hematopoietic stem cells [51]. Their differentiation pathway is common to ... Th17 cells), T cells, natural killer T (NKT) cells, NK cells, lymphoid tissue inducer (LTi) cells, neutrophils, and mast cells ... RANKL-RANK interaction sends signals into the cells through TNFR-associated factors (TRAFs). Cellular sarcoma (c-Src) and ... The hematopoietic system provides the cytokines and growth factors required for bone cell regeneration. Mesenchymal stem cells ...
  https://www.hindawi.com/journals/ecam/2013/518094/