*  Interleukin-3 receptor - Wikipedia
... induces tyrosine phosphorylation within the cell and promotes proliferation and differentiation within the hematopoietic cell ... The receptor belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the ... The interleukin-3 receptor (also known as CD123 antigen) is a molecule found on cells which helps transmit the signal of ... The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. ...
  https://en.wikipedia.org/wiki/Interleukin-3_receptor
*  Interleukin 3 - Wikipedia
Klein BK, Feng Y, McWherter CA, Hood WF, Paik K, McKearn JP (1997). "The receptor binding site of human interleukin-3 defined ... He found a T cell derived factor that induced the synthesis of 20alpha-hydroxysteroid dehydrogenase in hematopoietic cells and ... "Molecular characterization of colony-stimulating factors and their receptors: human interleukin-3". Ann. N. Y. Acad. Sci. 554: ... Interleukin 3 (IL-3) is a protein that in humans is encoded by the IL3 gene. Interleukin 3 is an interleukin, a type of ...
  https://en.wikipedia.org/wiki/Interleukin_3
*  The receptor binding site of human interleukin-3 defined by mutagenesis and molecular modeling. - Semantic Scholar
... of the cytokine superfamily that promotes multi-potential hematopoietic cell growth by interacting with a cell surface receptor ... map to one side of the protein and form a putative binding site for the alpha subunit of the receptor. A model of the IL-3.IL-3 ... receptor complex based on the human growth hormone (hGH).hGH soluble receptor complex structure suggests that the interface ... likely to be required for interaction with the receptor. Ten important and solvent-exposed residues, Asp21, Gly42, Glu43, Gln45 ...
  https://www.semanticscholar.org/paper/The-receptor-binding-site-of-human-interleukin-3-d-Klein-Feng/54585dbe4f6528c4562475093b82b0d4a9502f54
*  The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor...
IL-3 + SCF than to FL + IL-3 or SCF + IL-3. Similar findings were observed in serum-containing and serum-deprived cultures. ... IL-3 + SCF stimulated 2.3-fold and 2.5-fold more colonies than FL + IL-3 and SCF + IL-3, respectively. These additional ... 3, granulocyte colony-stimulating factor (G-CSF), CSF-1, granulocyte macrophage (GM) CSF stem cell factor (SCF), and IL-6. FL ... but synergistically and directly enhanced colony formation in combination with interleukin (IL) ...
  https://www.rdm.ox.ac.uk/publications/573533
*  Papers with the keyword KMT2 | Read by QxMD
Regulation of interleukin-3 receptor (IL-3R) gene expression by tumor necrosis factor alpha (TNF alpha) was investigated using ... a concave surface of the Ash2L SPIa and ryanodine receptor (SPRY) domain binds to a cluster of acidic residues, referred to as ... Tumor necrosis factor alpha-induced up-regulation of interleukin-3 receptor mRNA expression in a CD34-positive hematopoietic ... www.readbyqxmd.com/read/7545455/tumor-necrosis-factor-alpha-induced-up-regulation-of-interleukin-3-receptor-mrna-expression-in- ...
  https://www.readbyqxmd.com/keyword/21292
*  Regulation of interleukin 3 receptor alpha chain (IL-3R alpha)...
... on human monocytes by interleukin (IL)-4, IL-10, IL-13, and transforming growth factor beta (TGF- ... Regulation of interleukin 3 receptor alpha chain (IL-3R alpha) ... is constitutively expressed on committed haematopoietic stem ... This receptor is also expressed by monocytes and may induce functional activation. Interleukin (IL)-4, IL-10, IL-13, and ... Regulation of interleukin 3 receptor alpha chain (IL-3R alpha) on human monocytes by interleukin (IL)-4, IL-10, IL-13, and ...
  https://www.mysciencework.com/publication/show/regulation-interleukin-3-receptor-alpha-chain-il-3r-alpha-human-monocytes-interleukin-il-4-il-10-il-13-transforming-gro-701bcc94
*  Interleukin 11 - Wikipedia
1995). "Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11". Blood. 86 (7): ... As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Sims NA, Jenkins BJ, Nakamura A, Quinn JM, Li R, Gillespie MT, Ernst M, Robb L, Martin TJ (July 2005). "Interleukin-11 receptor ... 1999). "Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis". Eur. J. Biochem ...
  https://en.wikipedia.org/wiki/Interleukin_11
*  Most recent papers with the keyword fourts b | Read by QxMD
FDCP-1 cells are hematopoietic progenitor cells which require interleukin-3 for survival and proliferation. FDCP-1 cells stably ... Transfected cells expressing either the long form of the PRL receptor or the EPO receptor were used. We demonstrated that IL-3 ... Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells. ... induces-interleukin-6-and-cyclooxygenase-2-expression-in-human-vascular-smooth-muscle-cells-synergy-with-interleukin-1beta ...
  https://www.readbyqxmd.com/keyword/91320
*  CD123-PC7 - Beckman Coulter
... belongs to the cytokine receptor family. It is constitutively expressed by committed hematopoietic stem / progenitor cells, by ... The CD123 antigen, alias Interleukin-3 alpha receptor (IL-3Rα), ... CD123, IL-3Ralpha, Interleukin-3 receptor alpha chain. UNSPSC ...
  https://www.beckman.com/reagents/coulter-flow-cytometry/antibodies-and-kits/single-color-antibodies/B13647?loopPrevention=1
*  Interleukin 8 receptor, beta - Wikipedia
"Melanoma growth stimulatory activity enhances the phosphorylation of the class II interleukin-8 receptor in non-hematopoietic ... Interleukin 8 receptor, alpha Interleukin 8 Interleukin Interleukin receptor Cluster of differentiation G protein-coupled ... "Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to ... "Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to ...
  https://en.wikipedia.org/wiki/Interleukin_8_receptor,_beta
*  CD131 / CSF2RB antibody | acris-antibodies.com
Interleukin 3 (IL3), originally called Colony Forming Unit-Stimulating Activity (CFU-SA) is a multifunctional cytokine produced ... The IL3 receptor complex contains two distinct cytokine receptor subunits, ligand binding IL3 Ralpha and IL3 Rbeta. Recombinant ... Interleukin 3 binds specifically and with high affinity to cell-surface receptors. Interleukin 3 receptors are members of the ... IL3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. It ...
  https://www.acris-antibodies.com/target/cd131-antibody-csf2rb-antibody.htm
*  Interleukin-7 receptor-α - Wikipedia
Akashi K, Kondo M, Weissman IL (1999). "Role of interleukin-7 in T-cell development from hematopoietic stem cells". Immunol. ... IL7R-α is a type I cytokine receptor and is a subunit of the functional Interleukin-7 receptor and Thymic Stromal Lymphopoietin ... "Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor ... Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans ...
  https://en.wikipedia.org/wiki/Interleukin-7_receptor-%CE%B1
*  Interleukin 5 - Wikipedia
Interleukin 5 has been shown to interact with Interleukin 5 receptor alpha subunit. The IL-5 receptor is composed of an α and a ... IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other ... is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin ... "A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the ...
  https://en.wikipedia.org/wiki/Interleukin_5
*  Interleukin 11 - wikidoc
1995). "Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11.". Blood. 86 (7): ... As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... 1999). "Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis.". Eur. J. ... Yang YC, Yin T (1993). "Interleukin-11 and its receptor.". BioFactors. 4 (1): 15-21. PMID 1292471.. ...
  http://wikidoc.org/index.php/IL-11
*  ASMscience | Detection of Anticytokin
3); chronic mucocutaneous candidiasis due to anti-IL-17 and anti-IL-22 autoantibodies (4, 5); and cryptococcal meningitis (6) ... staphylococcal infection due to anti-interleukin-6 (IL-6) autoantibodies (2); Burkholderia gladioli infection due to anti-IL- ... Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte- ... Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science 332:65-68.[CrossRef].[PubMed ...
  http://www.asmscience.org/content/book/10.1128/9781555818722.ch39
*  Search Results
Hematopoietic stem cells. BXD. GNF Stem Cells U74Av2 (Mar04) RMA. 99030_at. interleukin 7 receptor; distal 3' UTR. Chr15: ... interleukin 7 receptor. Chr15: 9.506221. -2.224. 48 Liver. BHF2. UCLA BHF2 Liver (June05) mlratio. 10024416345. interleukin 7 ... interleukin 7 receptor; intron 5. Chr15: 9.512098. 6.899. 33 Spleen. BXD. IoP Affy MOE 430v2 Spleen (May09) RMA. 1448576_at. ... interleukin 7 receptor; 3' UTR. Chr15: 9.506393. 6.896. 35 Nucleus accumbens. BXD. VCU BXD NAc Sal M430 2.0 (Oct07) RMA. ...
  http://www.genenetwork.org/webqtl/WebQTL.py?cmd=sch&geneid=16197&species=mouse
*  Demonstration of early functional compromise of bone marrow derived hematopoietic progenitor cells during bovine neonatal...
Chen J, Ma A, Young F, Alt FW: IL-2 receptor alpha chain expression during early B lymphocyte differentiation. Int Immunol. ... Gazzola MV, Collins NH, Tafuri A, Keever CA: Recombinant interleukin 3 induces interleukin 2 receptor expression on early ... Clonogenic assay of hematopoietic progenitor cells. A protocol based on a previously described method [20] was followed with ... Hematopoietic progenitor cell cultures. BM-HPC cultures demonstrated normal colony development in the control animals at both ...
  https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-5-599
*  Patent US6139832 - Leukocyte adhesion inhibitor-1 (LAI-1) Polypeptides - Google Patents
Peptide mimotopes that inhibits interaction between a platelet receptor and a platelet receptor ligand. ... Labelled interleukin-8 and medical uses thereof. US5605817 *. Jan 19, 1995. Feb 25, 1997. Incyte Pharmaceuticals, Inc.. DNA ... For example, LAI-1 and Ck beta-11 can be employed for the expansion of immature hematopoietic progenitor cells, for example, ... Interleukin Genetics, Inc.. Diagnostics and therapeutics for an obstructive airway disease. US7332302. Oct 12, 2005. Feb 19, ...
  http://www.google.com/patents/US6139832?dq=6650327
*  Get to know the Ozgene team - Ozgene
Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte ... Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation. [ ... Adult mice with targeted mutation of the interleukin 11 receptor (IL11Ra) display normal hematopoiesis. [Read] ... EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. [Read] ...
  https://www.ozgene.com/about-us/our-team
*  Interleuchina 3 - Wikipedia
Klein BK, Feng Y, McWherter CA, et al., The receptor binding site of human interleukin-3 defined by mutagenesis and molecular ... Mroczko B, Szmitkowski M, Hematopoietic cytokines as tumor markers., in Clin. Chem. Lab. Med., vol. 42, nº 12, 2005, pp. 1347- ... Tabira T, Chui DH, Fan JP, et al., Interleukin-3 and interleukin-3 receptors in the brain., in Ann. N. Y. Acad. Sci., vol. 840 ... Le Beau MM, Epstein ND, O'Brien SJ, et al., The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid ...
  https://it.wikipedia.org/wiki/Interleuchina_3
*  Haematopoiesis - Wikipedia
Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to ... There are other important glycoprotein growth factors which regulate the proliferation and maturation, such as interleukins IL- ... which binds to the c-kit receptor on the HSC. Absence of SCF is lethal. ... In this case, the haematopoietic microenvironment prevails upon some of the cells to survive and some, on the other hand, to ...
  https://en.wikipedia.org/wiki/Haematopoiesis
*  Methods of using enantiomerically pure hydroxylated xanthine compounds - Patent # 5652243 - PatentGenius
3,7-disubstituted xanthine. The inventive compounds are effective in modulating cellular response to external or in situ ... a methodto prevent the down-regulation of receptors for cytokines in TNF-treated hematopoietic progenitor cells and said amount ... and interleukin-1 alpha (IL-1.alpha.) or interleukin-2 (IL-2). CT1501R was added to the cells at the doses indicated two hours ... cellular responses to IL-1 mediated through the IL-1 Type 1 receptor (but not the IL-1 Type 2 receptor), the TNFType 1 receptor ...
  http://www.patentgenius.com/patent/5652243.html
*  Patent US7601814 - Reducing the immunogenicity of fusion proteins - Google Patents
... region of a fusion protein in order to identify a T-cell epitope and reduce its ability to interact with a T cell receptor. ... thereby reducing its interaction with a T-cell receptor. Methods of the invention involve analyzing, changing, or modifying one ... "Interleukin 2 Receptor-Targeted Cytotoxicity: Interleukin 2 Receptor-mediated Action of a Diphtheria Toxin-related Interleukin ... Methods of stimulating hematopoietic cells with flt3-ligand. US5854205. 22 Oct 1996. 29 Dec 1998. The Children's Medical Center ...
  http://www.google.ca/patents/US7601814
*  PIK3R1 - Wikipedia
Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation". J. Biol. Chem. 272 (46 ... and Yes in response to the hematopoietic cytokine interleukin-11". Biochem. Biophys. Res. Commun. 224 (2): 289-96. doi:10.1006/ ... "The CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cells". J. Biol. Chem ... mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves ...
  https://en.wikipedia.org/wiki/PIK3R1
*  Interleukin 6 is a permissive factor for monocytic colony formation by human hematopoietic progenitor cells. | JEM
As a second approach, we added a monoclonal antibody directed against the IL-6 receptor to cultures of monocyte- and T cell- ... Interleukin 6 is a permissive factor for monocytic colony formation by human hematopoietic progenitor cells.. J H Jansen, J C ... Interleukin 6 is a permissive factor for monocytic colony formation by human hematopoietic progenitor cells. ... or paracrine production of this factor is involved in colony formation by normal hematopoietic progenitor cells. We added a ...
  http://jem.rupress.org/content/175/4/1151