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*  Erythropoietin and Erythropoietin Receptor Expression in Human Cancer | Cancer Research
Autocrine stimulation by erythropoietin of autonomous growth of human erythroid leukemic cells in vitro. J. Clin. Investig., 88 ... Sustained activation of the EPOR by EPO is known to block apoptosis in hematopoietic progenitors (14 , 15) . If EPO signaling ... and induce differentiation of RBC precursors (1) . Expression of EPO and EPOR has recently been demonstrated in several ... HeLa cervical carcinoma cells, SHSY5Y neuroblastoma cells, U87 glioblastoma cells, U251 glioma cells, and U373 glioma cells. ...
  http://cancerres.aacrjournals.org/content/61/9/3561.long
*  NUDT11 Gene - GeneCards | NUD11 Protein | NUD11 Antibody
span" data-trigger="SectionLoaded"> Blood (Hematopoietic System) * Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Kidney ( ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ... Hematopoietic Stem Cells Hematopoietic Bone Marrow *span" data-trigger="SectionLoaded"> Epithelial Cells * Presumptive ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=NUDT11
*  RYR3 Gene - GeneCards | RYR3 Protein | RYR3 Antibody
span" data-trigger="SectionLoaded"> Blood (Hematopoietic System) * Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone ... span" data-trigger="SectionLoaded"> Spleen (Hematopoietic System) * Conventional Dendritic Cells II Spleen ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RYR3 Gene. ... Knock-down of the type 3 ryanodine receptor impairs sustained Ca2+ signaling via the T cell receptor/CD3 complex. (PMID: ...
  http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=6263
*  EREG Gene - GeneCards | EREG Protein | EREG Antibody
span" data-trigger="SectionLoaded"> Blood (Hematopoietic System) * Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Ovary ( ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for EREG Gene. ... Epiregulin: roles in normal physiology and cancer. (PMID: 24631357) Riese DJ … Cullum RL (Seminars in cell & developmental ...
  https://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=2069
*  Serum Endoglin Levels in Patients Suffering from Systemic Sclerosis and Elevated Systolic Pulmonary Arterial Pressure
... erythroid precursors [22], and a hematopoietic stem cell subpopulation [23]. Although its role remains elusive, circulating ... H.-J. Buhring, C. A. Muller, M. Letarte et al., "Endoglin is expressed on a subpopulation of immature erythroid cells of normal ... "Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells," Proceedings of ... "Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line," ...
  https://www.hindawi.com/journals/ijr/2010/969383/
*  Is Pulp Inflammation a Prerequisite for Pulp Healing and Regeneration?
... biological response modifiers and the family of cell adhesion-promoting molecules. ... primitive mesenchymal cells, erythroid cells, megakaryocytes, hematopoietic precursor cells, and osteo/odontoblast progenitors ... Immunocompetent cells, and especially T-lymphocytes (CD8+ T cells), differentiate into cytotoxic T cells and CD4+ T cells. They ... Direct cell-cell interactions between diploid fibroblasts induce cell activation leading to programmed cell death. Nemosis of ...
  https://www.hindawi.com/journals/mi/2015/347649/
*  Complex interactions in EML cell stimulation by stem cell factor and IL-3. - PubMed - NCBI
Erythroid myeloid lymphoid (EML) cells are an established multipotent hematopoietic precursor cell line that can be maintained ... Complex interactions in EML cell stimulation by stem cell factor and IL-3.. Ye ZJ1, Gulcicek E, Stone K, Lam T, Schulz V, ... The cells were cultured for 2 d and counted with Trypan blue to exclude dead cells. (B) Ab-1 blocks synergistic phosphorylation ... The cells were washed with PBS and then lysed. The cell lysates immunoprecipitated with IL-3R β-chain antibody and ...
  https://www.ncbi.nlm.nih.gov/pubmed?term=21383156
*  Podoplanin-positive periarteriolar stromal cells promote megakaryocyte growth and proplatelet formation in mice by CLEC-2 |...
2 Hematopoietic precursors are committed to megakaryocyte lineages via megakaryocyte-erythroid precursors. Megakaryocyte ... 31 CAR cells are niche cells that serve not only to maintain hematopoietic cells, but also to regulate erythrocyte and B-cell ... The BM stromal cell layer contained ∼10% BM FRC-like cells, and all PDPN+ stromal cells were BM FRC-like cells (Figure 3A). ... we carefully pipetted drops of fixative into the wells and fixed cells for 1 hour to preserve cell-cell contacts. Cells were ...
  http://www.bloodjournal.org/content/127/13/1701?sso-checked=true
*  SWAP-70 regulates erythropoiesis by controlling α4 integrin | Haematologica
... is expressed in hematopoietic stem cells and myeloid-erythroid precursors. Although Swap-70-/- mice are not anemic, ... SWAP-70 deficiency impairs colony-forming unit erythroid (CFU-E) development, while burst-forming unit erythroid (BFU-E) ... Allogeneic stem cell transplantation benefits for patients ≥ 60 years with acute myeloid leukemia and FLT3-ITD; a study from ... Results We show that SWAP-70, a protein involved in cytoskeletal F-actin rearrangements and integrin regulation in mast cells, ...
  http://www.haematologica.org/content/early/2011/08/31/haematol.2011.050468
*  Trapped by scientists: antimatter, cholesterol and red blood cells | www.scienceinschool.org
... a novel tool for resolving the erythroid potential of hematopoietic precursors. Blood 118(11): 2988-2992. doi: 10.1182/blood- ... With the new technique, cells in a mouse's bone marrow turn fluorescent green only when they commit to becoming red blood cells ... will help scientists to understand which groups of stem cells give rise to red blood cells, and to probe the molecular ... EMBL: Making red blood cells green. Scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have ...
  https://www.scienceinschool.org/2011/issue21/eiroforum
*  CD34− Hematopoietic Stem Cells: Current Concepts and Controversies - Guo - 2003 - STEM CELLS - Wiley Online Library
Aging Increases Nuclear Chromatin Entropy of Erythroid Precursor Cells in Mice Spleen Hematopoietic Tissue, Microscopy and ... Searching for hematopoietic stem cells: evidence that Thy-1.1loLin−Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 ... observed engraftment of human hematopoietic cells with Lin−CD34− BM cells [29]. Human CD34+ cells have also been detected in ... Side population (SP) cells from different precursor compartments have distinct stem cell potential. J Hematother Stem Cell Res ...
  http://onlinelibrary.wiley.com/doi/10.1634/stemcells.21-1-15/full?globalMessage=0
*  Hemophagocytic Lymphohistiocytosis in a Patient With Nodular Lymphocyte-Predominant Hodgkin Lymphoma: A Case Report
... including nucleated erythroid precursors, white blood cell precursors, and platelets-which are best depicted in marrow aspirate ... Bone marrow examination often reveals characteristic hemophagocytes- histocytes with engulfed hematopoietic elements, ... Interestingly, cyclin D1 was also expressed by cells consistent with LP cells (large, pleomorphic cells having highly lobated ... cells (Figure). LP cells expressed CD45, CD20, CD79a, BCL6, and epithelial membrane antigen, and lacked expression of CD10, ...
  https://www.onclive.com/publications/invited-presentations/2017/june-2017/hemophagocytic-lymphohistiocytosis-in-a-patient-with-nodular-lymphocytepredominant-hodgkin-lymphoma-a-case-report
*  Gene Editing in Adult Hematopoietic Stem Cells | IntechOpen
Gene Editing in Adult Hematopoietic Stem Cells , IntechOpen, Published on: 2016-05-18. Authors: Sergio López-Manzaneda, Sara ... induction of production of fetal hemoglobin in human erythroid precursor cells. Int J Mol Med. 2009;23:105-11. ... Cell Stem Cell. 2012;10:120-36.. 4 - Stolfi JL, Pai CS, Murphy WJ. Preclinical modeling of hematopoietic stem cell ... Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. Cell Stem Cell. 2014;15:643-52. ...
  https://www.intechopen.com/books/modern-tools-for-genetic-engineering/gene-editing-in-adult-hematopoietic-stem-cells/
*  In vivo analysis of the role of aberrant histone deacetylase recruitment and RARα blockade in the pathogenesis of acute...
Indeed, RA inhibits the proliferation of hematopoietic precursors and promotes the terminal granulocytic differentiation of ... granulocyte/monocyte progenitors and multipotent erythroid/monocytic cells. Vitamin A deficiency, unligated RARα, RARα ... Cells were retrovirally transduced as indicated. Transduced cells were isolated by cell sorting and cultured with or without 2 ... Luciferase assay in transfected 293 cells. (black bars) RA-treated cells; (white bars) untreated cells. Luciferase activities ...
  http://jem.rupress.org/content/203/4/821
*  Patent US6306575 - Methods for preparing enriched human hematopoietic cell preparations - Google Patents
The cell conjugates are removed and a cell preparation is obtained which is enriched in human hematopoietic progenitor cells ... A process is also provided for enriching and recovering human hematopoietic progenitor cells and stem cells in a sample ... and/or antibodies specific for antigen expressed on non-hematopoietic tumor cells under conditions so that cell conjugates are ... containing human hematopoietic differentiated, progenitor, and stem cells, and optionally tumor cells. The process involves ...
  http://www.google.com/patents/US6306575?dq=5,838,906
*  B cell growth factor 1 Dictionary Definition and More from Dictionary.net
... hematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. ... previousB cell gene rearrangements next B cell growth factor i B cell growth factor 1. ... Interleukin- 4 induces the expression of class II major histocompatibility complex and Fc receptors on B- cells. It also acts ... Definitions of B Cell Growth Factor 1. * Soluble factor produced by activated T- lymphocytes that causes proliferation and ...
  http://www.dictionary.net/b%20cell%20growth%20factor%201
*  Red Blood Cells - Circulatory System - Merck Veterinary Manual
Learn about the veterinary topic of Red Blood Cells. Find specific details on this topic and related topics from the Merck Vet ... and cell-cell interactions between erythroid precursors, lymphoid cells, and other components of the hematopoietic ... Red Blood Cells By Susan M. Cotter, DVM, DACVIM (Small Animal, Oncology), ... or antibodies directed against RBC precursors. Malignancy of RBCs or their precursors may be acute (eg, erythroleukemia) or ...
  http://www.merckvetmanual.com/en-pr/circulatory-system/hematopoietic-system-introduction/red-blood-cells
*  Iron overload in myelodysplastic syndromes (MDS)
... through unfavorable effects on mesenchymal stromal cells as well a hematopoietic cells, particularly erythroid precursors. ...
  http://ijhgateway.net/ArticlePage.aspx?DOI=10.1007/s12185-017-2367-1
*  Hematopoietic stem cell niche - Wikipedia
Choi K, Kennedy M, Kazarov A, Papadimitriou JC, Keller G (1998). "A common precursor for hematopoietic and endothelial cells" ( ... "Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish". Dev. Cell. 8 (1): 97-108. doi: ... immune cells, and even platelets all originate from the same progenitor cell, the hematopoietic stem cell (HSC). As these cells ... 2010). "Regulation of the HIF-1α level is essential for hematopoietic stem cells". Stem Cell. 7 (3): 391-402. doi:10.1016/j. ...
  https://en.wikipedia.org/wiki/Hematopoietic_stem_cell_niche
*  CD117 (c-Kit) Antibody Staining Protocol for Immunohistochemistry
... multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid precursors of B and T lymphocytes. ... Description: This antibody reacts with CD117 which in adult bone marrow is expressed on hematopoietic progenitor cells ...
  http://www.ihcworld.com/_protocols/antibody_protocols/cd117_2b8_rdi.htm
*  Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management...
The importance of erythroid expansion in determining the extent of apoptosis in erythroid precursors in patients with beta- ... hematopoietic stem cell transplantation is still the only available curative option. The use of hematopoietic stem cell ... Allogeneic hematopoietic stem-cell transplantation for sickle cell disease. N Engl J Med. 2009;361(24):2309-17. ... Outcome of hematopoietic cell transplantation in children with sickle cell disease, a single center's experience. Bone Marrow ...
  http://www.haematologica.org/content/99/5/811
*  Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoietic deficient immune...
... cells replaced with hematopoietic cells from a hematopoietic deficient mammal donor, and optionally in which xenogeneic cells ... Alternatively, the xenogeneic cells or tissue may be non-hematopoietic, such as normal or pathological cells or tissue, which ... The xenogeneic, preferably human, cells or tissue may be hematopoietic cells, in which case the chimeric mammal can produce ... xenogeneic B and/or T cells, and can be used as a source of mammalian, preferably human, monoclonal antibodies and/or T cells. ...
  http://www.patentgenius.com/patent/5709843.html
*  E2F4 (E2F transcription factor 4, p107/p130-binding)
... display a marked macrocytic anemia caused by impaired cell cycle progression and proliferation of fetal erythroid precursors ... proposed that E2F4 is particularly abundant in hematopoietic tissues (i.e. thymus, spleen and bone marrow) and in the gut, in ... E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells.. ... In immortalized fibroblasts and certain cancer cells, E2F4 is expressed in the nucleus of quiescent cells and as cells progress ...
  http://atlasgeneticsoncology.org/Genes/GC_E2F4.html
*  Stem Cells Flashcards by Prachi Patel | Brainscape
2)CMP (progenitor cell for granulocytes, monocytes, erythrocytes) 3) MEP- Megakaryocyte Erythroid Precursor cell 4a) ... Hematopoeitic (bone marrow). -Messenchymal (bone marrow). -Intestinal epithelial stem cells (intestines). -Skin (Hair follicle) ... They can develop into more than one cell type but are limited I.e.: adult stem cells and cord blood stem cells ... Embryonic stem cells are pluripotent stem cells derived from the inner cell mass of a blastocyst ...
  https://www.brainscape.com/flashcards/stem-cells-5325444/packs/7951019
*  T Cell Lineage Commitment: Identity and Renunciation | The Journal of Immunology
Stepwise commitment of T cell precursors. Hematopoietic stem cells begin with access to ≥10 distinguishable fates, including ... precursors have lost the ability to make erythroid cells and megakaryocytes, but the most immature cells in the thymus clearly ... Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic ... Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell 1: 578-591. ...
  http://www.jimmunol.org/content/186/12/6649