*  NUDT11 Gene - GeneCards | NUD11 Protein | NUD11 Antibody
span" data-trigger="SectionLoaded"> Blood (Hematopoietic System) * Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Kidney ( ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ... Hematopoietic Stem Cells Hematopoietic Bone Marrow *span" data-trigger="SectionLoaded"> Epithelial Cells * Presumptive ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=NUDT11
*  RYR3 Gene - GeneCards | RYR3 Protein | RYR3 Antibody
span" data-trigger="SectionLoaded"> Blood (Hematopoietic System) * Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone ... span" data-trigger="SectionLoaded"> Spleen (Hematopoietic System) * Conventional Dendritic Cells II Spleen ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RYR3 Gene. ... Knock-down of the type 3 ryanodine receptor impairs sustained Ca2+ signaling via the T cell receptor/CD3 complex. (PMID: ...
  http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=6263
*  Complex interactions in EML cell stimulation by stem cell factor and IL-3. - PubMed - NCBI
Erythroid myeloid lymphoid (EML) cells are an established multipotent hematopoietic precursor cell line that can be maintained ... Complex interactions in EML cell stimulation by stem cell factor and IL-3.. Ye ZJ1, Gulcicek E, Stone K, Lam T, Schulz V, ... The cells were cultured for 2 d and counted with Trypan blue to exclude dead cells. (B) Ab-1 blocks synergistic phosphorylation ... The cells were washed with PBS and then lysed. The cell lysates immunoprecipitated with IL-3R β-chain antibody and ...
  https://www.ncbi.nlm.nih.gov/pubmed?term=21383156
*  SWAP-70 regulates erythropoiesis by controlling α4 integrin | Haematologica
... is expressed in hematopoietic stem cells and myeloid-erythroid precursors. Although Swap-70-/- mice are not anemic, ... SWAP-70 deficiency impairs colony-forming unit erythroid (CFU-E) development, while burst-forming unit erythroid (BFU-E) ... Allogeneic stem cell transplantation benefits for patients ≥ 60 years with acute myeloid leukemia and FLT3-ITD; a study from ... Results We show that SWAP-70, a protein involved in cytoskeletal F-actin rearrangements and integrin regulation in mast cells, ...
  http://www.haematologica.org/content/early/2011/08/31/haematol.2011.050468
*  Gene Editing in Adult Hematopoietic Stem Cells | IntechOpen
Gene Editing in Adult Hematopoietic Stem Cells , IntechOpen, Published on: 2016-05-18. Authors: Sergio López-Manzaneda, Sara ... induction of production of fetal hemoglobin in human erythroid precursor cells. Int J Mol Med. 2009;23:105-11. ... Cell Stem Cell. 2012;10:120-36.. 4 - Stolfi JL, Pai CS, Murphy WJ. Preclinical modeling of hematopoietic stem cell ... Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. Cell Stem Cell. 2014;15:643-52. ...
  https://www.intechopen.com/books/modern-tools-for-genetic-engineering/gene-editing-in-adult-hematopoietic-stem-cells/
*  Podoplanin-positive periarteriolar stromal cells promote megakaryocyte growth and proplatelet formation in mice by CLEC-2 |...
2 Hematopoietic precursors are committed to megakaryocyte lineages via megakaryocyte-erythroid precursors. Megakaryocyte ... 31 CAR cells are niche cells that serve not only to maintain hematopoietic cells, but also to regulate erythrocyte and B-cell ... The BM stromal cell layer contained ∼10% BM FRC-like cells, and all PDPN+ stromal cells were BM FRC-like cells (Figure 3A). ... we carefully pipetted drops of fixative into the wells and fixed cells for 1 hour to preserve cell-cell contacts. Cells were ...
  http://www.bloodjournal.org/content/127/13/1701?sso-checked=true
*  Red Blood Cells - Circulatory System - Merck Veterinary Manual
Learn about the veterinary topic of Red Blood Cells. Find specific details on this topic and related topics from the Merck Vet ... and cell-cell interactions between erythroid precursors, lymphoid cells, and other components of the hematopoietic ... Red Blood Cells By Susan M. Cotter, DVM, DACVIM (Small Animal, Oncology), ... or antibodies directed against RBC precursors. Malignancy of RBCs or their precursors may be acute (eg, erythroleukemia) or ...
  http://www.merckvetmanual.com/en-pr/circulatory-system/hematopoietic-system-introduction/red-blood-cells
*  Patent US6306575 - Methods for preparing enriched human hematopoietic cell preparations - Google Patents
The cell conjugates are removed and a cell preparation is obtained which is enriched in human hematopoietic progenitor cells ... A process is also provided for enriching and recovering human hematopoietic progenitor cells and stem cells in a sample ... and/or antibodies specific for antigen expressed on non-hematopoietic tumor cells under conditions so that cell conjugates are ... containing human hematopoietic differentiated, progenitor, and stem cells, and optionally tumor cells. The process involves ...
  http://www.google.com/patents/US6306575?dq=5,838,906
*  Hemoglobin Expression in Nonerythroid Cells: Novel or Ubiquitous?
... cell biology and pharmacology of inflammation, including acute/chronic inflammation, mediators of inflammation, as well as ... that regulation of Hb synthesis in the ATII cells occurs in similar fashion as it takes place in erythroid precursor cells. ... However, alveolar macrophages did not show expression of any of the genes involved in hematopoietic development. They have ... mesangial cells of rat and human [16], hepatocytes [17], neuronal/glial cells [18], endometrial cells [19], and cervical cells ...
  https://www.hindawi.com/journals/iji/2014/803237/
*  CD34− Hematopoietic Stem Cells: Current Concepts and Controversies - Guo - 2003 - STEM CELLS - Wiley Online Library
Aging Increases Nuclear Chromatin Entropy of Erythroid Precursor Cells in Mice Spleen Hematopoietic Tissue, Microscopy and ... Searching for hematopoietic stem cells: evidence that Thy-1.1loLin−Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 ... observed engraftment of human hematopoietic cells with Lin−CD34− BM cells [29]. Human CD34+ cells have also been detected in ... Side population (SP) cells from different precursor compartments have distinct stem cell potential. J Hematother Stem Cell Res ...
  http://onlinelibrary.wiley.com/doi/10.1634/stemcells.21-1-15/full?globalMessage=0
*  In vivo analysis of the role of aberrant histone deacetylase recruitment and RARα blockade in the pathogenesis of acute...
Indeed, RA inhibits the proliferation of hematopoietic precursors and promotes the terminal granulocytic differentiation of ... granulocyte/monocyte progenitors and multipotent erythroid/monocytic cells. Vitamin A deficiency, unligated RARα, RARα ... Cells were retrovirally transduced as indicated. Transduced cells were isolated by cell sorting and cultured with or without 2 ... Luciferase assay in transfected 293 cells. (black bars) RA-treated cells; (white bars) untreated cells. Luciferase activities ...
  http://jem.rupress.org/content/203/4/821
*  E2F4 Modulates Differentiation and Gene Expression in Hematopoietic Progenitor Cells during Commitment to the Lymphoid Lineage ...
... precursor cells are defective in erythroid differentiation, leading to anemia in surviving E2F4-deficient mice (15, 17). To ... Reconstitution analysis for LSK cells, CLP-like cells, CMP-like cells, DN1 thymocytes, pre-B and pro-B cells, GMP-like cells, ... fetal liver cells to differentiation from cells corresponding to multilineage stem cells (the LSK cells) to cells corresponding ... LSK cells and CLP-like cells from reconstituted mice were sorted using a FACSAria cell sorter (BD Biosciences). Cells were ...
  http://www.jimmunol.org/content/180/6/3699.long
*  B cell growth factor 1 Dictionary Definition and More from Dictionary.net
... hematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. ... previousB cell gene rearrangements next B cell growth factor i B cell growth factor 1. ... Interleukin- 4 induces the expression of class II major histocompatibility complex and Fc receptors on B- cells. It also acts ... Definitions of B Cell Growth Factor 1. * Soluble factor produced by activated T- lymphocytes that causes proliferation and ...
  http://www.dictionary.net/b%20cell%20growth%20factor%201
*  T Cell Lineage Commitment: Identity and Renunciation | The Journal of Immunology
Stepwise commitment of T cell precursors. Hematopoietic stem cells begin with access to ≥10 distinguishable fates, including ... precursors have lost the ability to make erythroid cells and megakaryocytes, but the most immature cells in the thymus clearly ... Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic ... Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell 1: 578-591. ...
  http://www.jimmunol.org/content/186/12/6649
*  CD36, eFluor 660, clone: eBioNL07 (NL07), eBioscience™ 25 Tests; eFluor 660 CD36, eFluor 660, clone: eBioNL07 (NL07),...
... smooth muscle cells, and hematopoietic cells, including erythroid precursors, platelets, monocytes/macrophages, DCs and ... Cell Culture & Analysis Cell Culture & Analysis * Cell Culture Dishes, Plates and Flasks ... Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor® 660 is a replacement for Alexa ... A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. ...
  https://www.fishersci.co.uk/shop/products/cd36-mouse-anti-human-efluor-660-clone-ebionl07-nl07-ebioscience/15549876
*  Concise Review: The Bone Marrow Niche as a Target of Graft Versus Host Disease - Bonin - 2014 - STEM CELLS - Wiley Online...
... and erythroid precursors declined as well. This disturbance in maturation was most distinctive in the B-cell lineage, whereas ... Both hematopoietic cells and cells that form the hematopoietic stem and progenitor cell niche have been identified as targets ... Regulatory T cells and natural killer T cells for modulation of GVHD following allogeneic hematopoietic cell transplantation. ... In the latter case, hematopoietic cells and immunocompetent cells are both donor-derived, while stromal cells remain host- ...
  http://onlinelibrary.wiley.com/doi/10.1002/stem.1691/full?globalMessage=0
*  Human embryonic stem cells: prospects for development | Development
Hematopoietic precursors have been obtained from hES cells by either co-culturing or by inducing them with growth factors. In ... The precursors could form erythroid and myeloid colonies in agar, and the yield of colony-forming units, which showed some ... The cytotrophoblast cell layer (the precursor cell of all other trophoblasts), where active cell division continues, is ... Cynomolgus monkey ES cells have also been shown to differentiate into endothelial precursors by culturing them on a feeder cell ...
  http://dev.biologists.org/content/131/22/5515
*  Erythropoietin in spinal cord injury
... which stimulates proliferation and differentiation of erythroid precursor cell [45]. In addition, a recent clinical trial ... This property confers loss of hematopoietic activity in human cell cultures or upon chronic dosing in animal models [13]. ... Comparison with receptor properties of erythroid cells. J Biol Chem. 1993;268:11208-11216. [PubMed] ... Inflammatory cells such as neutrophils, macrophages, and resident microglia are attracted by the dead cells and further amplify ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2899410/
*  Macrophage Precursors as Biomarker for LRRK2-associated Parkinson disease | Parkinson's Disease
Therefore, we established a colony forming cell (CFC) assay to study hematopoietic stem cell differentiation from peripheral ... Using the CFC assay we assess the direct effect of secreted signaling proteins on hematopoiesis by counting erythroid, ... macrophage and granulocyte precursor cells. Our preliminary data suggest that the proportion of different precursor cells is ... assay as the most suitable assay to assess proliferation and differentiation in hematopoietic precursor cells. ...
  https://www.michaeljfox.org/foundation/grant-detail.php?grant_id=720
*  FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells. - Radcliffe Department of Medicine
... potential are restricted to cells with high levels of cell-surface FLT3 expression, whereas HSCs and MkE progenitors lack ... These findings are compatible with FLT3 cell-surface expression not being detectable in the fully multipotent stem/progenitor ... in which FLT3 already is expressed in multipotent stem/progenitor cells. The expression pattern of Flt3 (mRNA) and FLT3 ( ... cell compartment in mice. If so, this process could be distinct from human hematopoiesis, ...
  https://www.rdm.ox.ac.uk/publications/246643
*  Hematopoietic stem cell niche - Wikipedia
Choi K, Kennedy M, Kazarov A, Papadimitriou JC, Keller G (1998). "A common precursor for hematopoietic and endothelial cells" ( ... "Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish". Dev. Cell. 8 (1): 97-108. doi: ... immune cells, and even platelets all originate from the same progenitor cell, the hematopoietic stem cell (HSC). As these cells ... 2010). "Regulation of the HIF-1α level is essential for hematopoietic stem cells". Stem Cell. 7 (3): 391-402. doi:10.1016/j. ...
  https://en.wikipedia.org/wiki/Hematopoietic_stem_cell_niche
*  CMDT Media Library | AccessMedicine | McGraw-Hill Medical
... the marrow fat and normal hematopoietic cells have been replaced by leukemic cells. In this example of CLL, the leukemic cells ... There are numerous erythroid precursors with iron-laden mitochondria encircling the nucleus. These are referred to as ringed ... the marrow fat and normal hematopoietic cells have been replaced by leukemic cells. In this example of CLL, the leukemic cells ... When more than 15% of erythroid cells are ringed sideroblasts, the diagnosis of refractory anemia with ringed sideroblasts is ...
  http://accessmedicine.mhmedical.com/MediaLibrary.aspx?termId=19005
*  Modeling Bone Marrow Progenitor Cell Differentiation and Susceptibility to HIV-1 Infection | MedCrave
... hematopoietic precursor cells blocked at an early stage of hematopoietic differentiation and express several erythroid and ... which includes hematopoietic stem cells, ancestral hematopoietic progenitor cells, as well as more mature hematopoietic ... TF-1 cells were treated with PMA (300 ng/ml) for 15 min at a cell density of 2 × 106 cells/ml, at 37°C. The cells were then ... Cell culture and cell treatments. The TF-1 CD34+ erythro-myeloid leukemia cell line (ATCC, Manassas, VA) was grown in RPMI 1640 ...
  http://googlescholar.medcraveonline.com/scholars/article_fulltext/195
*  Printing...
... including nucleated erythroid precursors, white blood cell precursors, and platelets-which are best depicted in marrow aspirate ... Although hematopoietic stem cell transplantation in familial HLH has been shown to improve outcomes, its role in secondary ... HRS cells), also known as LP cells. These display an intact B-cell program, expressing pan B-cell markers including CD20 and ... Interestingly, cyclin D1 was also expressed by cells consistent with LP cells (large, pleomorphic cells having highly lobated ...
  http://www.gotoper.com/print_pub.php?url=/publications/ajho/2017/2017feb/hemophagocytic-lymphohistiocytosis-in-a-patient-with-nodular-lymphocyte-predominant-hodgkin-lymphoma-a-case-report
*  ZNF384-related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic...
Enrichment plots for the hematopoietic stem cells (HSCs), multi-lymphoid progenitor (MLP), pro-B cell (Pro-B), early T-cell ... and megakaryocyte-erythroid progenitor cell (MEP) signatures are presented. Bold lines represent significant enrichments {false ... such as Pro-B cells and early T-cell precursors (ETP), were more prominent in TCF3-PBX1-positive ALL (Figure 4C and Online ... B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a heterogeneous disease that can be subdivided according to primary ...
  http://www.haematologica.org/content/102/1/118