G-protein alpha subunit interaction and guanine nucleotide dissociation inhibitor activity of the dual GoLoco motif protein PCP ... Dive into the research topics of G-protein alpha subunit interaction and guanine nucleotide dissociation inhibitor activity of ...
GDP dissociation inhibitor-alpha, and guanine nucleotides". J. Biol. Chem. 270 (19): 11085-90. doi:10.1074/jbc.270.19.11085. ... Shisheva A, Chinni SR, DeMarco C (1999). "General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: ...
... guanosine nucleotide dissociation inhibitor, and guanine exchange factor. ...
Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 ... Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 ... Rho guanine nucleotide dissociation inhibitor; ROCK, Rho kinase; SFM, serum-free medium; VVO, vesiculo-vacuolar organelle; WGA ... Rho guanine nucleotide dissociation inhibitor; ROCK, Rho kinase; SFM, serum-free medium; VVO, vesiculo-vacuolar organelle; WGA ...
... guanine-nucleotide-dissociation inhibitor) and are stabilized there after nucleotide exchange by effector binding. In the ... Prenylated Rabs also occur in the cytosol bound to GDI (guanine nucleotide dissociation inhibitor), which binds to Rabs in ... QUANTITATIVE-ANALYSIS OF THE INTERACTIONS BETWEEN PRENYL RAB9, GDP DISSOCIATION INHIBITOR-ALPHA, AND GUANINE-NUCLEOTIDES ... as shown by a reduction in the capacity of Rab9 for guanine nucleotide dissociation inhibitor-mediated extraction from Niemann- ...
Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers. Clin Cancer Res 9( ...
... which requires both the guanine nucleotide dissociation inhibitor (GDI) Rdi1, which extracts Cdc42 from the peripheral membrane ... which binds both active Cdc42GTP and its guanine nucleotide exchange factor (GEF) or activator Cdc24. It was thought that Bem1 ...
... from the G protein-geranyl-geranyl interaction face of the Ig-like domain of the Rho guanine nucleotide dissociation inhibitor ... Sjolinder, M., Uhlmann, J. and Ponsting, H. (2002). DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, ... In order to identify the function of deafness locus putative guanine nucleotide exchange factor (DelGEF), a protein homologous ... On epidermal growth factor (EGF) stimulation, activated Ras recruits guanine nucleotide exchange factors (GEFs) for RalA, ...
... regulated by guanine nucleotide-exchange factors GTPase-activating proteins and guanine nucleotide-dissociation inhibitors (1 ... There have been limited successes with molecules that disrupt the binding of guanine nucleotide exchange factors to RAC and ... Although inhibitors of RHO GTPases and their downstream signaling kinases have not yet been widely adopted for clinical use ... For example RAC and CDC42 share two protein serine-threonine kinase effectors in common - PAK and MLK - and inhibitors for both ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS); or exchange GTP for GDP; (GUANINE NUCLEOTIDE EXCHANGE FACTORS).. Terms. GTP- ... GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS); or exchange GTP for GDP; (GUANINE NUCLEOTIDE EXCHANGE FACTORS).. Entry Version. ... Guanine Nucleotide Dissociation Inhibitors [D12.644.360.325.225] * Guanine Nucleotide Exchange Factors [D12.644.360.325.300] ... Guanine Nucleotide Dissociation Inhibitors [D12.776.476.325.225] * Guanine Nucleotide Exchange Factors [D12.776.476.325.300] ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS. INIBIDORES DE DISSOCIAÇÃO DO NUCLEOTÍDIO GUANINA. INHIBIDORES DE LA ANGIOGENESIS. ... GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES DE TROCA DO NUCLEOTÍDIO GUANINA. FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR. FATOR RAL DE TROCA DO NUCLEOTÍDIO GUANINA. ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA. ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS. INIBIDORES DE DISSOCIAÇÃO DO NUCLEOTÍDIO GUANINA. INHIBIDORES DE LA ANGIOGENESIS. ... GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES DE TROCA DO NUCLEOTÍDIO GUANINA. FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR. FATOR RAL DE TROCA DO NUCLEOTÍDIO GUANINA. ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA. ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS. INIBIDORES DE DISSOCIAÇÃO DO NUCLEOTÍDIO GUANINA. INHIBIDORES DE LA ANGIOGENESIS. ... GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES DE TROCA DO NUCLEOTÍDIO GUANINA. FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR. FATOR RAL DE TROCA DO NUCLEOTÍDIO GUANINA. ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA. ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INIBIDORES DE DISSOCIAÇÃO DO ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL DE TROCA DO NUCLEOTÍDIO ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INIBIDORES DE DISSOCIAÇÃO DO ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL DE TROCA DO NUCLEOTÍDIO ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INJEÇÕES DE ESPERMA ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR DE CRESCIMENTO NEURAL NERVE GROWTH FACTOR ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS. INIBIDORES DE DISSOCIAÇÃO DO NUCLEOTÍDIO GUANINA. INHIBIDORES DE LA ANGIOGENESIS. ... GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES DE TROCA DO NUCLEOTÍDIO GUANINA. FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR. FATOR RAL DE TROCA DO NUCLEOTÍDIO GUANINA. ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA. ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INIBIDORES DE DISSOCIAÇÃO DO ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL DE TROCA DO NUCLEOTÍDIO ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INJEÇÕES DE ESPERMA ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR DE CRESCIMENTO NEURAL NERVE GROWTH FACTOR ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INIBIDORES DE DISSOCIAÇÃO DO ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL DE TROCA DO NUCLEOTÍDIO ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INIBIDORES DE DISSOCIAÇÃO DO ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL DE TROCA DO NUCLEOTÍDIO ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS INHIBIDORES DE DISOCIACION DE GUANINA NUCLEOTIDO INJEÇÕES DE ESPERMA ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR DE CRESCIMENTO NEURAL NERVE GROWTH FACTOR ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA ... RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL ...
... guanine nucleotide dissociation inhibitor; GFP: green fluorescent protein; GOLGA2: golgin A2; HOPS: homotypic fusion and ... Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1. Mao, Hongmei; Tang, Zaiming; Li, Hua; Sun, Bo; Tan ... Here, we report an unexpected finding that MLN4924, a small molecule inhibitor of NEDD8-activating enzyme (NAE), blocks primary ... Collectively, our study demonstrates an unexpected role of a neddylation inhibitor in regulation of ciliogenesis via AKT1, and ...
An additional negative control is achieved through Rho guanine nucleotide dissociation inhibitors (GDIs). They bind Rho GTPases ... The exchange of GDP to GTP and thus the activation of Rho GTPases is catalyzed by guanine nucleotide exchange factors (GEFs), ... Schmidt A, Hall A: Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev. 2002, 16: 1587-1609. ... Matos P, Collard JG, Jordan P: Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors ...
Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers. Clin Cancer Res. ... Discovery of small molecule cMET inhibitors: evolution and profile of clinical candidates. Anti-Cancer Agent Med Chem. 2010;in ... HGF specific antagonist and small molecule inhibitors [34, 35, 38-40]. A combined strategy in targeting both HGF and RhoC may ... the cycle being regulated by a number of activators and inhibitors. Three isoforms of Rho, Rho A, B and C, show a high degree ...
Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C- ... Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. ...
Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C- ... Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. ...
Guanine nucleotide exchange factors (GEFs) and Guanine nucleotide dissociation inhibitors (GDIs), regulate Rho GTPases. Read ... The subcellular localization and activity of the Rab proteins depend on their nucleotide-bound states and the cycling between ... In terms of spatial integration, cyclic nucleotides can regulate growth cone behaviours by converting repulsive signals into ...
... guanine nucleotide dissociation inhibitors (GDIs) and guanine nucleotide exchange factors (GEFs). The best characterized ...
The molecule, Rho guanine nucleotide dissociation inhibitor α (RhoGDIα), slowed down muscle glucose uptake and hindered ... The molecule, Rho guanine nucleotide dissociation inhibitor α (RhoGDIα), slowed down muscle glucose uptake and hindered ... The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action. , Proceedings of the ...