Most recent papers with the keyword CYP17A1 | Read by QxMD
Sex determination is a process triggering differentiation of the gonads into the testis or ovary. Sex determination period is ... Development of the gonads is a complex process, which starts with a period of undifferentiated, bipotential gonads. During this ... Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads. ... 29518581/transcriptome-analysis-identifies-genes-involved-in-sex-determination-and-development-of-xenopus-laevis-gonads ...https://www.readbyqxmd.com/keyword/119416
Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to...
Although the mechanisms of avian sex determination remains unknown, the genetic sex is experimentally reversible by in ovo ... Sex of birds is genetically determined through inheritance of the ZW sex chromosomes (ZZ males and ZW females). ... Sex Determination Processes. Sex Differentiation / drug effects, genetics. Testis / drug effects, embryology. ... Although the mechanisms of avian sex determination remains unknown, the genetic sex is experimentally reversible by in ovo ...http://www.biomedsearch.com/nih/Masculine-Epigenetic-Sex-Marks-Promoter/22539680.html
Conserved sex chromosomes in iguanas | Biology Letters
... the process called sex determination, responsible for the decision whether the undifferentiated gonad will turn into a testis ... Cretaceous park of sex determination: sex chromosomes are conserved across iguanas Message Subject (Your Name) has sent you a ... Cretaceous park of sex determination: sex chromosomes are conserved across iguanas. Michail Rovatsos, Martina Pokorná, Marie ... Cretaceous park of sex determination: sex chromosomes are conserved across iguanas. Michail Rovatsos, Martina Pokorná, Marie ...http://rsbl.royalsocietypublishing.org/content/10/3/20131093
Capel Lab | Primary sex determination and gonadogenesis research
The gonad, which arises as a bipotential primordium, is an ideal model system for studying the processes of cell fate ... WCOM "Radio In Vivo": Sex determination in the human embryo and "the bipotential gonad," drivers of sex determination in ... The primary step in sex determination is the decision that occurs within the bipotential gonad to differentiate as a testis or ... In XX gonads, the female sub-network dominates and represses the male pathway. However, expression of the Y-linked male sex- ...https://sites.duke.edu/blanchecapellab/
Identification of the Major Sex-Determining Region of Turbot (Scophthalmus maximus) | Genetics
The phenotypic sex depends on the processes of both sex determination and sex differentiation. Exogenous factors, such as ... Sex was recorded by examining gonad morphology after biopsy. Afamilies were constituted by 3-year-old fish, and sex could be ... Other minor factors in turbot sex determination:. The results discussed thus far explain most observations of sex determination ... Sex determination in fish can evolve very rapidly (Woram et al. 2003; Peichel et al. 2004; Ross et al. 2009). Different sex ...http://www.genetics.org/content/183/4/1443
Books by Subject - Lane Medical Library - Stanford University School of Medicine
A Role of microRNAs in Cell Differentiation during Gonad Development -- The Battle of the Sexes: Human Sex Development and its ... The Gonadal Supporting Cell Lineage and Mammalian Sex Determination: the Differentiation of Sertoli and Granulosa Cells -- ... Mesonephric cell migration into the gonads and vascularization are processes crucial for testis development -- Origin and ... Determination of gene promoter activity in skeletal muscles in vivo / Sarah M. Senf and Andrew R. Judge -- Determination of ...http://lane.stanford.edu/biomed-resources/ebsubjectbrowse.html?m=Cell%20Biology&page=3
Human genetics | biology | Britannica.com
Human sex determination is a genetic process that depends basically on the presence of the Y chromosome in the fertilized egg. ... It is of interest that in the absence of a male gonad (testicle) the internal and external sex anatomy is always female, even ... The sex of an individual can be thought of in three different contexts: chromosomal sex, gonadal sex, and anatomic sex. ... Fertilization, sex determination, and differentiation. A human individual arises through the union of two cells, an egg from ...https://www.britannica.com/science/human-genetics
Human sex determination is a genetic process that depends basically on the presence of the Y chromosome in the fertilized egg. ... It is of interest that in the absence of a male gonad (testicle) the internal and external sex anatomy is always female, even ... The XY sex-determination system is the sex-determination system found in humans, most other mammals, some insects (Drosophila ... The XY sex-determination system is the sex-determination system found in humans, most other mammals, some insects (Drosophila ...https://www.euvolution.com/futurist-transhuman-news-blog/category/human-genetics
ZFIN Publication: Chen et al., 2016
Gonads/physiology*; Male; Mutation/genetics*; Ovary/physiology; Sex Determination Processes/genetics; Sex Differentiation/ ... Sex determinations are diverse in vertebrates. Although many sex-determining genes and pathways are conserved, the mechanistic ... DAX1, Sex determination, Somatic cell, Zebrafish, nr0b1. MeSH Terms:. Animals; Caspase 3/genetics; Cell Differentiation/ ... Disorders of Sex Development/genetics; Disorders of Sex Development/pathology; Female; ...http://zfin.org/ZDB-PUB-160610-17
Staff - Eawag
The molecular mechanisms governing sex determination and differentiation in the zebrafish (Danio rerio) are not fully ... The identified proteins mark the trail of AgNPs processing in the cells like a forensic fingerprint: the cells take up the ... study the candidate sex-related proteins in zebrafish which were selected based on a global proteomics analysis of adult gonads ... LC-MS/MS determination of tralopyril in water samples A targeted analytical method was established to determine tralopyril (4- ...http://www.eawag.ch/en/aboutus/portrait/organisation/staff/profile/marc-suter/show/
NMDA receptor activation upstream of methyl farnesoate signaling for short day-induced male offspring production in the water...
Sex determination is a fundamental developmental process that contributes to the establishment of sexually dimorphic traits, ... including the sexual differentiation of gonads, and leads to sex-specific differences in behavior and physiology. Sex ... genotypic sex determination (GSD) and environmental sex determination (ESD) [1-3]. GSD is attributed to the genetic segregation ... To elucidate up- and downstream events of MF signaling during sex determination processes, we compared the transcriptomes of ...https://rd.springer.com/article/10.1186/s12864-015-1392-9
Molecular patterns of sex determination in the animal kingdom: a comparative study of the biology of reproduction |...
... sex is determined by the ratio of X chromosomes to autosomes and the sex switching gene, sxl. Another model organism whose sex ... This mechanism is also known as single-locus complementary sex determination (slCSD). On the other hand, for Dipterans and ... the process is also described as temperature-dependent sex determination and the developmental stage of sex determination is ... Genetic model of sex determination in humans. The formation of the undifferentiated/bipotential gonad is controlled by several ...https://rbej.biomedcentral.com/articles/10.1186/1477-7827-4-59
Ryuya Fukunaga, Ph.D.
Interestingly, piRNAs are recently implicated also in sex determination, neuronal functions in brain, and tumorigenesis in ... piRNAs (26-31 nt) are mostly produced in gonads (ovaries and testes). Unlike miRNAs and siRNAs, Dicer enzymes are not involved ... piRNAs are produced in the primary processing pathway and the ping-pong pathway, which are not yet fully understood (Figure 1 ... siRNA is loaded to Argonaute2 and silences highly complementary target RNAs by cleaving them-a process typically called RNAi. ...https://www.hopkinsmedicine.org/profiles/results/directory/profile/3173205/ryuya-fukunaga
Blanche Capel - Department of Cell Biology
Sex Determination, Testis and Ovary Development, and Germ Cell Biology. The process of sex determination in mammals is ... dominant genetic switch are complex antagonistic signaling pathways that wage the battle of the sexes in the bipotential gonad ... Lin YT, Capel B. (2015). Cell fate commitment during mammalian sex determination. Curr Opin Genet Dev. 32:144-52. ... Other work in the lab centers on a comparison to temperature dependent sex determination in the red eared slider turtle ...http://www.cellbio.duke.edu/blanche-capel/
Fibroblast growth factor elisa and antibody
... male gonad development; male sex determination; negative regulation of transcription from RNA polymerase II promoter; negative ... phosphatidylcholine biosynthetic process; phospholipid biosynthetic process; positive chemotaxis; positive regulation of cell ... Biological Process: cell differentiation; fibroblast growth factor receptor s. >>>. ignaling pathway; inner ear receptor cell ... Biological Process: cell-cell signaling; fibroblast growth factor receptor signaling pathway; MAPKKK cascade; nervous system ...https://www.mybiosource.com/protein_family.php?root=fibroblast-growth-factor
Genomic analysis of the appearance of testicular oocytes in MRL/MpJ mice, Mammalian Genome | 10.1007/s00335-012-9405-3 |...
Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription ... Gonads undergo a unique developmental process because of. their bipotential nature, i.e., the ability to differentiate into a ... Delayed Sry and Sox9 expression in developing mouse gonads underlies B6-Y DOM sex reversal ... Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal ...https://www.deepdyve.com/lp/springer_journal/genomic-analysis-of-the-appearance-of-testicular-oocytes-in-mrl-mpj-2EAPNLQiGB
Migration of mesonephric cells into the mammalian gonad depends on Sr" by B Capel, K H. Albrecht et al.
The mechanisms by which Sry controls this process are unknown. Studies showed that cell migration from the adjacent mesonephros ... Here we provide genetic proof that Sry is the only Y-linked gene necessary for cell migration into the gonad. Cell migration ... only occurs into XY gonads; however, it was not known whether this effect depended on Sry, another Y-linked gene, or the ... from the mesonephros into the differentiating gonad is consistently associated with Sty's presence and with testis cord ...https://mouseion.jax.org/stfb1990_1999/1293/
A Novel Candidate Gene for Temperature-Dependent Sex Determination in the Common Snapping Turtle | Genetics
We hypothesize that CIRBP might play a similar regulatory role in RNA processing during sex determination in snapping turtles. ... We also detect significant associations between CIRBP genotype, CIRBP expression in embryonic gonads, and sex determination at ... 2004 Temperature-dependent sex determination in lizards, pp. 42-52 in Temperature-Dependent Sex Determination in Vertebrates, ... The key event during sex determination in gonochoristic vertebrates is irreversible commitment of the bipotential gonads to ...http://www.genetics.org/content/203/1/557?ijkey=69c2e1eb7a274fbf07ebd0274ee58c51cd6d6c24&keytype2=tf_ipsecsha
WNT4 - Wikipedia
They later commit to sex determination, becoming either female or male under normal circumstances. Regardless of sex, though, ... In mouse gonads, it has been detected only eleven days after fertilization. If deficient in XY mice, there is a delay in ... These processes are all necessary for the development of an embryo. Ablation in female mice results in subfertility, with ... With no FGF2, there is a partial sex reversal. With no FGF9, there is a full sex reversal. Both cases are rescued, though, by a ...https://en.wikipedia.org/wiki/WNT4
Nuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish, Endocrinology | 10.1210/en.2017...
... a process described as polygenic sex determination (13). Genes known to play an important role in zebrafish sex determination ... sex determination but not early gonad differentiation Our data suggest that nuclear AR influences male sex determination in ... a process described as polygenic sex determination (13). Genes known to play an important role in zebrafish sex determination ... Zebrafish exhibit unique sex determination and differentiation mechanisms. Laboratory strains lack a sex chromosome, and no sex ...https://www.deepdyve.com/lp/ou_press/nuclear-androgen-receptor-regulates-testes-organization-and-oocyte-UnZ3V3IDgP
Boy or Girl: How Genetics Determine Your Baby's Gender | Parents
The process by which your baby becomes a boy or a girl, according to what's written in his or her genetic code, is awe- ... So, here's a primer on sex determination. Humans have 1 pair of sex chromosomes. Women have 2 X chromosomes and men have an X ... Many parents begin to wonder about the sex of their baby as soon as they discover they're having a baby. The biological process ... What's at work here? Male and female hormones caused the embryonic gonad and 2 sets of ducts to form male or female structures ...https://www.parents.com/pregnancy/my-baby/gender-prediction/boy-or-girl-how-genetics-determine-your-babys-gender/
0101-URO-GENITAL & CARDIO-RESPIRATORY SYSTEMS
The process of sex determination is not random; Allah determines it. Sex is determined by the predominance of either the female ... The gonads produce gametes in addition to sex hormones. The sex hormones further define gender. Androgens are musculinizing and ... In the process of fertilization, equal numbers of chromosomes are contributed from the father and the mother. For each gene ... Menstruation is a normal process (MB# #203 p 142) at the end of each ovarian cycle. Unlike Judaism, Islam does not make a ...http://omarkasule01.tripod.com/id705.html
SOX9 in the developing gonad plays a critical role in male sex determination by stimulating expression of anti-Mullerian ... a process that is strongly androgen dependent, and undergo atrophy or apoptosis in response to androgen withdrawal. In contrast ... Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development 2004; 131: 1891-901. ... Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9. Cell 1994; 79 ...http://cancerres.aacrjournals.org/content/67/2/528
PA-18-658: Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional)
Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional) PA-18-658. ORWH ... hormone production and gonad formation) * Biological mechanisms underlying common physiological or pathophysiological processes ... Determination of unique properties of in vitro cell cultures at various stages, such as between the time of known genetic sex ( ... describe sex and gender-based studies: * Sex-based studies: Sex is the classification of living things, generally as male or ...https://grants.nih.gov/grants/guide/pa-files/PA-18-658.html
Interestingly, piRNAs are recently implicated also in sex determination, neuronal functions in brain, and tumorigenesis in ... We examine how L. pneumophila is able to manipulate host cell processes to establish growth within its host and the impact of ... piRNAs (26-31 nt) are mostly produced in gonads (ovaries and testes). Unlike miRNAs and siRNAs, Dicer enzymes are not involved ... This process is of fundamental biological importance. The accurate response to extracellular signals results in a cell's ...http://biolchem.bs.jhmi.edu/Pages/Faculty.aspx?ra=0