*  Jamey Marth - Wikipedia
Marth's early studies of glycosylation and glycan linkages revealed a profound effect on immunity and contributed substantially ... relationships between aberrant glycan linkages and autoimmune diseases including the fact that alterations of glycan linkages ... These studies further explained how glycan linkages function in the origins of disease at the metabolic and cellular levels. ... Green, R.S.; Stone, E.L. Tenno; Lehtonen, E.; Farquhar, M.G.; Marth, J.D. (2007). "Mammalian N-glycan branching protects ...
  https://en.wikipedia.org/wiki/Jamey_Marth
*  Site specific protein O -glucosylation with bacterial toxins - Chemical Communications (RSC Publishing) DOI:10.1039/C6CC06223G
Although this is an unnatural glycosylation it provides a method to generate the important glycan-protein linkage, for which ... Although these products will contain an unnatural glycan-protein linkage, the properties of the glycan that can influence ... Glycosylation is an important and prevalent protein post-translational modification.1 In recent decades, the chemical synthesis ... S5, ESI†) with a glycosylation yield of approximately 80% based on ESI-MS (80%, Fig. S5, ESI†). Driven by these preliminary ...
  http://pubs.rsc.org/en/content/articlehtml/2016/cc/c6cc06223g
*  Patent US5846763 - DNA encoding tumor necrosis factor stimulated gene 6 (TSG-6) - Google Patents
Potential glycosylation sites for N-linked glycans are shown by double broken lines. Potential chondroitin sulfate linkage site ... Also depicted are two potential N-glycosylation sites (ball and stick) and a chondroitin sulfate linkage site (asterisk and ... An operable linkage is a linkage in which the regulatory DNA sequences and the DNA sequence sought to be expressed are ... For this reason, it is preferable to ensure that the linkage between a eukaryotic promoter and a DNA sequence which encodes the ...
  http://www.google.com/patents/US5846763?dq=7,603,356
*  Glycosylation Analysis | Life Sciences | SGS
... to find out how SGS's world-class Glycosylation Analysis can help determine how post-translational factors have affected glycan ... linkage or composition of glycans within a protein, it is also a key tool in helping to protect your business's reputation for ... Home › Life Sciences › Biopharmaceutical Services › Laboratory Services › Glycosylation Analysis Life Sciences Glycosylation ... Glycosylation of Proteins: Structure, Function & Analysis. Download Glycosylation of Proteins: Structure, Function & Analysis ...
  http://www.sgs.com/en/life-sciences/biopharmaceutical-services/laboratory-services/glycosylation-analysis
*  Yeast Expression Support-Getting Started | Thermo Fisher Scientific
3 glycan linkages whereas Pichia pastoris does not. It is believed that the α1,3 glycan linkages in glycosylated proteins ... Both Saccharomyces cerevisiae and Pichia pastoris have a majority of N-linked glycosylation of the high-mannose type; however, ... However, it is important to note that yeast glycosylation does differ from that in mammalian cells: in S. cerevisiae, O-linked ... In comparison to Saccharomyces cerevisiae, Pichia may have an advantage in the glycosylation of secreted proteins because it ...
  https://www.thermofisher.com/us/en/home/technical-resources/technical-reference-library/protein-expression-support-center/yeast-expression-support/yeast-expression-support-getting-started.html
*  The Dystroglycanopathies: The New Disorders of O-Linked Glycosylation
O-linked glycosylation typically occurs via an alpha linkage of the glycan to the hydroxyl group of a serine or threonine ... Genes affecting dystroglycan glycosylation associated with congenital muscular dystrophy. The O-mannose-linked glycans on α ... Unlike some disorders of glycosylation, where loss of glycosylation leads to loss of protein expression or targeting, the ... Not surprisingly, given that these are disorders of glycosylation, this approach involves the stimulation of glycosylation in ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2860379/
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Like pd-A1PI, Hu-recA1PI was modified by N-linked glycosylation on N46, N83, and N246. Unlike pd-A1PI, most glycans on recA1P1 ... were core fucosylated via ?(1-6) linkage. In addition, significantly higher amounts of tri- and tetraantennary glycans were ... Hu-recA1PI glycans were differentially distributed, with N46 containing mostly biantennary glycans, N83 containing primarily ... These differences in glycosylation contributed to the apparent higher molecular weight and lower isoelectric point (pI) of Hu- ...
  https://www.jove.com/visualize?author=Zihao+Wang
*  Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins | Protocol
... depending on the specific amino acid and atom bridging the linkage. In N-glycosylation, glycans are attached to the side chain ... O-glycosylation refers to the addition of glycans, usually to the side chain hydroxyl group of Ser or Thr residues, and this ... Glycosylation is the covalent attachment and processing of oligosaccharide structures, also known as glycans, through various ... Davis, B. G., Lloyd, R. C., Jones, J. B. Controlled site-selective protein glycosylation for precise glycan structure-catalytic ...
  https://www.jove.com/video/56302/targeting-cysteine-thiols-for-vitro-site-specific-glycosylation
*  Anti-Apolipoprotein E antibody (FITC) | Abcam
O-glycosylated with core 1 or possibly core 8 glycans. Thr-307 is a minor glycosylation site compared to Ser-308.. Glycated in ... Synthesized with the sialic acid attached by O-glycosidic linkage and is subsequently desialylated in plasma. ...
  http://www.abcam.com/Apolipoprotein-E-antibody-FITC-ab27613.html
*  Discovery of Non-invasive Glycan Biomarkers for Detection and Surveillance of Gastric Cancer
High-throughput profiling of protein N-glycosylation by MALDI-TOF-MS employing linkage-specific sialic acid esterification. ... The abundance of the nine representative glycan groups in different cancer stages and controls. The N-glycans were grouped ... Release of N-glycans from glycoproteins: N-glycans were released from the human serum glycoproteins according to the method ... Serum N-glycan profiles. The N-glycan profiles were examined by MALDI-MS in non-cancer individuals (n=20) and in patients with ...
  http://www.jcancer.org/v08p1908.htm
*  Glycosylation - Wikipedia
... because almost every aspect of glycosylation can be modified, including: Glycosidic bond-the site of glycan linkage Glycan ... which is the addition of a GPI anchor that links proteins to lipids through glycan linkages. Glycosylation is the process by ... glycosylation is a site-specific modification. N-linked glycosylation is a very prevalent form of glycosylation and is ... disorders of lipid glycosylation and disorders of other glycosylation pathways and of multiple glycosylation pathways. No ...
  https://en.wikipedia.org/wiki/Glycosylation
*  Rare and unusual glycosylation of peptides and proteins - Natural Product Reports (RSC Publishing)
Glycosylation represents the most complex co- and post-translational modification of proteins. In addition to N- and O-glycans ... but also the type of the chemical linkage, ... Rare and unusual glycosylation of peptides and proteins Pierre ... Glycosylation represents the most complex co- and post-translational modification of proteins. In addition to N- and O-glycans ... Rare and unusual glycosylation of peptides and proteins P. Lafite and R. Daniellou, Nat. Prod. Rep., 2012, 29, 729 DOI: 10.1039 ...
  http://pubs.rsc.org/en/Content/ArticleLanding/2012/NP/C2NP20030A
*  Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta...
8Neu5Ac linkage. We could not detect any glycosylation of the Aβ1-38/40/42 isoforms. We observed an increase of up to 2.5 times ... APP/Aβ sialylated O-glycans, including that of a Tyr residue, the first in a mammalian protein, may modulate APP processing, ... In addition to 33 unglycosylated APP/Aβ peptides, we identified 37 APP/Aβ glycopeptides with sialylated core 1 like O-glycans ... The Tyr10 linked O-glycans were (Neu5Ac)(1-2)Hex(Neu5Ac)HexNAc-O-structures with the disialylated terminals occasionally O- ...
  http://www.uniprot.org/citations/21712440
*  anti-APOE antibody | anti-Mouse Apolipoprotein E (Apo E) Polyclonal Antibody-P02649.1
O-glycosylated with core 1 or possibly core 8 glycans. Thr-307 is a minor glycosylation site compared to Ser-308. Ref. ... Post-translational modification: Synthesized with the sialic acid attached by O-glycosidic linkage and is subsequently ...
  https://www.mybiosource.com/prods/Antibody/Polyclonal/Apolipoprotein-E-Apo-E/APOE/datasheet.php?products_id=315478
*  aminoisovaleric acid-alpha: Topics by WorldWideScience.org
... botulinum demonstrated that the protein is modified by a novel glycan moiety of mass 417 Da in O-linkage. Bioinformatic ... This is the first report of glycosylation of Gram-positive flagellar proteins by the 'sialic acid-like' nonulosonate sugar, ... Marker ions for novel glycans, as well as a unique C-terminal flagellin peptide marker ion, were identified in a top-down ... Flagellins from Clostridium botulinum were shown to be post-translationally modified with novel glycan moieties by top-down MS ...
  https://worldwidescience.org/topicpages/a/aminoisovaleric+acid-alpha.html
*  Intramolecular aglycon delivery - Wikipedia
This approach is generally used for the formation of difficult glycosidic linkages. Glycosylation reactions are very important ... Intramolecular aglycon delivery is a synthetic strategy for the construction of glycans. ... Chemical glycosylation Glycosyl halide Cumpstey, I. Carbohydr. Res. 2008, 343, 1553-1573 Barresi, F.; Hindsgaul, O. J. Am. Chem ... and present the greatest challenge in glycosylation reactions. One of the most recent approaches to prepare 1,2-cis-β- ...
  https://en.wikipedia.org/wiki/Intramolecular_aglycon_delivery