*  Jamey Marth - Wikipedia
Marth's early studies of glycosylation and glycan linkages revealed a profound effect on immunity and contributed substantially ... relationships between aberrant glycan linkages and autoimmune diseases including the fact that alterations of glycan linkages ... These studies further explained how glycan linkages function in the origins of disease at the metabolic and cellular levels. ... Green, R.S.; Stone, E.L. Tenno; Lehtonen, E.; Farquhar, M.G.; Marth, J.D. (2007). "Mammalian N-glycan branching protects ...
  https://en.wikipedia.org/wiki/Jamey_Marth
*  Site specific protein O -glucosylation with bacterial toxins - Chemical Communications (RSC Publishing) DOI:10.1039/C6CC06223G
Although this is an unnatural glycosylation it provides a method to generate the important glycan-protein linkage, for which ... Although these products will contain an unnatural glycan-protein linkage, the properties of the glycan that can influence ... Glycosylation is an important and prevalent protein post-translational modification.1 In recent decades, the chemical synthesis ... S5, ESI†) with a glycosylation yield of approximately 80% based on ESI-MS (80%, Fig. S5, ESI†). Driven by these preliminary ...
  http://pubs.rsc.org/en/content/articlehtml/2016/cc/c6cc06223g
*  Patent US5846763 - DNA encoding tumor necrosis factor stimulated gene 6 (TSG-6) - Google Patents
Potential glycosylation sites for N-linked glycans are shown by double broken lines. Potential chondroitin sulfate linkage site ... Also depicted are two potential N-glycosylation sites (ball and stick) and a chondroitin sulfate linkage site (asterisk and ... An operable linkage is a linkage in which the regulatory DNA sequences and the DNA sequence sought to be expressed are ... For this reason, it is preferable to ensure that the linkage between a eukaryotic promoter and a DNA sequence which encodes the ...
  http://www.google.com/patents/US5846763?dq=7,603,356
*  Glycosylation Analysis | Life Sciences | SGS
... to find out how SGS's world-class Glycosylation Analysis can help determine how post-translational factors have affected glycan ... linkage or composition of glycans within a protein, it is also a key tool in helping to protect your business's reputation for ... Home › Life Sciences › Biopharmaceutical Services › Laboratory Services › Glycosylation Analysis Life Sciences Glycosylation ... Glycosylation of Proteins: Structure, Function & Analysis. Download Glycosylation of Proteins: Structure, Function & Analysis ...
  http://www.sgs.com/en/life-sciences/biopharmaceutical-services/laboratory-services/glycosylation-analysis
*  Yeast Expression Support-Getting Started | Thermo Fisher Scientific
3 glycan linkages whereas Pichia pastoris does not. It is believed that the α1,3 glycan linkages in glycosylated proteins ... Both Saccharomyces cerevisiae and Pichia pastoris have a majority of N-linked glycosylation of the high-mannose type; however, ... However, it is important to note that yeast glycosylation does differ from that in mammalian cells: in S. cerevisiae, O-linked ... In comparison to Saccharomyces cerevisiae, Pichia may have an advantage in the glycosylation of secreted proteins because it ...
  https://www.thermofisher.com/us/en/home/technical-resources/technical-reference-library/protein-expression-support-center/yeast-expression-support/yeast-expression-support-getting-started.html
*  The Dystroglycanopathies: The New Disorders of O-Linked Glycosylation
O-linked glycosylation typically occurs via an alpha linkage of the glycan to the hydroxyl group of a serine or threonine ... Genes affecting dystroglycan glycosylation associated with congenital muscular dystrophy. The O-mannose-linked glycans on α ... Unlike some disorders of glycosylation, where loss of glycosylation leads to loss of protein expression or targeting, the ... Not surprisingly, given that these are disorders of glycosylation, this approach involves the stimulation of glycosylation in ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2860379/
*  Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins | Protocol
... depending on the specific amino acid and atom bridging the linkage. In N-glycosylation, glycans are attached to the side chain ... O-glycosylation refers to the addition of glycans, usually to the side chain hydroxyl group of Ser or Thr residues, and this ... Glycosylation is the covalent attachment and processing of oligosaccharide structures, also known as glycans, through various ... Davis, B. G., Lloyd, R. C., Jones, J. B. Controlled site-selective protein glycosylation for precise glycan structure-catalytic ...
  https://www.jove.com/video/56302/targeting-cysteine-thiols-for-vitro-site-specific-glycosylation
*  Anti-Apolipoprotein E antibody (FITC) | Abcam
O-glycosylated with core 1 or possibly core 8 glycans. Thr-307 is a minor glycosylation site compared to Ser-308.. Glycated in ... Synthesized with the sialic acid attached by O-glycosidic linkage and is subsequently desialylated in plasma. ...
  http://www.abcam.com/Apolipoprotein-E-antibody-FITC-ab27613.html
*  Discovery of Non-invasive Glycan Biomarkers for Detection and Surveillance of Gastric Cancer
High-throughput profiling of protein N-glycosylation by MALDI-TOF-MS employing linkage-specific sialic acid esterification. ... The abundance of the nine representative glycan groups in different cancer stages and controls. The N-glycans were grouped ... Release of N-glycans from glycoproteins: N-glycans were released from the human serum glycoproteins according to the method ... Serum N-glycan profiles. The N-glycan profiles were examined by MALDI-MS in non-cancer individuals (n=20) and in patients with ...
  http://www.jcancer.org/v08p1908.htm
*  Glycosylation - Wikipedia
... because almost every aspect of glycosylation can be modified, including: Glycosidic bond-the site of glycan linkage Glycan ... which is the addition of a GPI anchor that links proteins to lipids through glycan linkages. Glycosylation is the process by ... glycosylation is a site-specific modification. N-linked glycosylation is a very prevalent form of glycosylation and is ... disorders of lipid glycosylation and disorders of other glycosylation pathways and of multiple glycosylation pathways. No ...
  https://en.wikipedia.org/wiki/Glycosylation
*  Rare and unusual glycosylation of peptides and proteins - Natural Product Reports (RSC Publishing)
Glycosylation represents the most complex co- and post-translational modification of proteins. In addition to N- and O-glycans ... but also the type of the chemical linkage, ... Rare and unusual glycosylation of peptides and proteins Pierre ... Glycosylation represents the most complex co- and post-translational modification of proteins. In addition to N- and O-glycans ... Rare and unusual glycosylation of peptides and proteins P. Lafite and R. Daniellou, Nat. Prod. Rep., 2012, 29, 729 DOI: 10.1039 ...
  http://pubs.rsc.org/en/Content/ArticleLanding/2012/NP/C2NP20030A
*  Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta...
8Neu5Ac linkage. We could not detect any glycosylation of the Aβ1-38/40/42 isoforms. We observed an increase of up to 2.5 times ... APP/Aβ sialylated O-glycans, including that of a Tyr residue, the first in a mammalian protein, may modulate APP processing, ... In addition to 33 unglycosylated APP/Aβ peptides, we identified 37 APP/Aβ glycopeptides with sialylated core 1 like O-glycans ... The Tyr10 linked O-glycans were (Neu5Ac)(1-2)Hex(Neu5Ac)HexNAc-O-structures with the disialylated terminals occasionally O- ...
  http://www.uniprot.org/citations/21712440
*  anti-APOE antibody | anti-Mouse Apolipoprotein E (Apo E) Polyclonal Antibody-P02649.1
O-glycosylated with core 1 or possibly core 8 glycans. Thr-307 is a minor glycosylation site compared to Ser-308. Ref. ... Post-translational modification: Synthesized with the sialic acid attached by O-glycosidic linkage and is subsequently ...
  https://www.mybiosource.com/prods/Antibody/Polyclonal/Apolipoprotein-E-Apo-E/APOE/datasheet.php?products_id=315478
*  Production of glycosylated polypeptides in micro algae - Institut Francais de Recherche pour l'Exploitation de la Mer (IFREMER)
To further caracterise the N-glycan structures, we are analysing N-glycosylation profiles of this recombinant murine EPO ... Such molecules are known in the art and include, for example, those in which peptide linkages substitute for phosphate linkages ... An enzyme X that acts on a lipid-linked glycan or on a N-glycan before enzyme Y is said to be or to act "upstream" to enzyme Y ... 3. N-linked glycans from Phaeodactylum tricornutum are high mannose type structures. MALDI-TOF MS of N-linked glycans released ...
  http://www.freepatentsonline.com/8728761.html
*  Intramolecular aglycon delivery - Wikipedia
This approach is generally used for the formation of difficult glycosidic linkages. Glycosylation reactions are very important ... Intramolecular aglycon delivery is a synthetic strategy for the construction of glycans. ... Chemical glycosylation Glycosyl halide Cumpstey, I. Carbohydr. Res. 2008, 343, 1553-1573 Barresi, F.; Hindsgaul, O. J. Am. Chem ... and present the greatest challenge in glycosylation reactions. One of the most recent approaches to prepare 1,2-cis-β- ...
  https://en.wikipedia.org/wiki/Intramolecular_aglycon_delivery
*  Linkage Analysis | Life Sciences | SGS
... linkage testing and methylation analysis to determine the identities of the various linkages between the monosaccharides ... we can provide a detailed picture of the glycans present and identify specific linkages of functional importance, such as 3- ... Home › Life Sciences › Contract Laboratory Services › Biopharmaceutical Characterization Services › Glycosylation Analysis › ... Life Sciences Linkage Analysis. Linkage analysis from SGS - linkage analysis to determine the identities of the various ...
  https://www.sgs.com/en/life-sciences/contract-laboratory-services/biopharmaceutical-characterization-services/glycosylation-analysis/linkage-analysis
*  Food composition comprising glucosamine - Nestec S.A.
Degradation occurs through the activity of enzymes for de-N-glycosylation (cleavage of glucosamine linkage between N-acetyl-D ... N-glycans influence the stability, solubility, and biological activity of the protein. De-N-glycosylation seems important ...
  http://www.freepatentsonline.com/8652532.html
*  Protocols and Video Articles Authored by Yu-Ju Chen
... ester linkages between the lectin and glycan subsequent to the initial recognition process and thus preserving its glycan- ... Finally, a remarkable false discovery rate of 0 was achieved on the N-glycosylation-free Escherichia coli data set. MAGIC is ... Using a linear glycan, HgTe@DHB NPs promote laser-induced extensive and intense dissociation of the glycan, superior to HgTe ... and linkage of labile sialylated glycans. The general utility of this approach was demonstrated by the characterization of ...
  https://www.jove.com/author/Yu-Ju_Chen
*  Anti-Apolipoprotein E4 抗体 (Biotin) (ab85976)
O-glycosylated with core 1 or possibly core 8 glycans. Thr-307 is a minor glycosylation site compared to Ser-308.. Glycated in ... Synthesized with the sialic acid attached by O-glycosidic linkage and is subsequently desialylated in plasma. ...
  http://www.abcam.co.jp/apolipoprotein-e4-antibody-biotin-ab85976.html
*  Most recent papers with the keyword sugar substitutes | Read by QxMD
... rely on glycosylation methodologies to construct the various glycosidic linkages. In this regard, a wide array of glycosylation ... Naturally occurring glycans and glycoconjugates have extremely diverse structures and biological functions. Syntheses of these ... Certainly, data over the years have indicated that this organism synthesises unusual N-glycans with a range of galactose and ... Previously, up to four fucose residues were detected on its N-glycans, despite these lacking the fucosylated antennae typical ...
  https://www.readbyqxmd.com/keyword/92092
*  Integral Options Cafe: Towards a Liquid Self: How Time, Geography, and Life Experiences Reshape the Biological Identity
Glycosylation is a form of co-translational and post-translational modification that attaches glycans to proteins, lipids, or ... A tight linkage was identified between the concentration of N-glycans depleted of galactose residues and the aging process, ... and the epigenetic modifications and mechanism of glycosylation in creating antigens signals (see "Age-Associated N-Glycans ... Age-Associated N-Glycans Modifications and Inflammation: When the Aged Self Becomes Non-Self. ...
  http://integral-options.blogspot.com/2014/10/towards-liquid-self-how-time-geography.html
*  Biomolecules | Free Full-Text | Glycobiology Aspects of the Periodontal Pathogen Tannerella forsythia | HTML
... glycosylation system. Protein O‑glycosylation impacts the life-style of T. forsythia since truncated S-layer glycans present in ... Recently, it was shown that Tannerella surface glycosylation has a role in restraining the Th17-mediated neutrophil ... the contribution of glycosylation to modulating host immunity is currently unraveling. ... The S-layer glycan has the structure 4‑MeO-b-ManpNAcCONH2-(1→3)-[Pse5Am7Gc-(2→4)-]-b-ManpNAcA-(1→4)-[4-MeO-a-Galp-(1→2)-]-a- ...
  http://www.mdpi.com/2218-273X/2/4/467/htm
*  Glycosyltransferases: Methods and Protocols by Wenjie Peng, Corwin M. Nycholat, Nahid Razi (auth.), Inka Brockhausen (eds.) -...
... transglycosylation and reverse glycosylation reactions. Glycosyltransferases: Methods and Protocols contains a wide range of ... are assembled by GTs which synthesize specific linkages between sugars or sugars and protein. This is in contrast to the non- ... are essential for the biosynthesis of complex glycoconjugates and are powerful tools to study the functions of complex glycans ...
  http://www.aacoa.net/bookinfo/glycosyltransferases-methods-and-protocols.pdf/
*  Glycosylation | definition of glycosylation by Medical dictionary
... glycosylation explanation free. What is glycosylation? Meaning of glycosylation medical term. What does glycosylation mean? ... Looking for online definition of glycosylation in the Medical Dictionary? ... glycosylation. /gly·co·syl·a·tion/ (gli-ko″sĭ-la´shun) the formation of linkages with glycosyl groups.. glycosylation. (glī′kō- ... Glycan motifs of mistletoe lectins of RIP II type and biological relevance ...
  http://medical-dictionary.thefreedictionary.com/glycosylation
*  PPT - Unicellular Organisms: Eubacteria, Archea, Yeast Lecture 27, Chapter 21 May 13, 2004 Jeff Esko PowerPoint Presentation...
Notice diversity of linkages. Similarity in sequence of N-linked attachment sites and mechanism of assembly of glycan (dolichol ... Overview -Cutured cell lines with genetically defined disorders of glycosylation lecture 33 may 25, 2004 jeff esko. overview. ... Bacterial wall glycans provide an exoskeleton, define shape, protect against turgor pressure, create antigenic serotypes, and ... Yeast produce many of the same glycans found in higher eukaryotes, but the mecahnism of assembly differs in subtle way ...
  https://www.slideserve.com/perrin/unicellular-organisms-eubacteria-archea-yeast-lecture-27-chapter-21-may-13-2004-jeff-esko