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*  Growth Hormone Secretagogue Receptor Type 1 (GH Releasing Peptide Receptor or Ghrelin Receptor or GHSR) - Pipeline Review, H2...
Growth Hormone Secretagogue Receptor Type 1 (GH Releasing Peptide Receptor or Ghrelin Receptor or GHSR) - Growth hormone ... Growth Hormone Secretagogue Receptor Type 1 (GH Releasing Peptide Receptor or Ghrelin Receptor or GHSR) - Overview *Growth ... Growth Hormone Secretagogue Receptor Type 1 (GH Releasing Peptide Receptor or Ghrelin Receptor or GHSR) - Pipeline Review, H2 ... Growth Hormone Secretagogue Receptor Type 1 (GH Releasing Peptide Receptor or Ghrelin Receptor or GHSR) - Drug Profiles * ...
  https://www.giiresearch.com/report/labd358687-growth-hormone-secretagogue-receptor-type-1-ghs-r.html
*  Luis de Lecea | Stanford Medicine Profiles
... binds ghrelin receptor growth hormone secretagogue receptor type 1a (GHS-R1a)]. To determine whether the role of endogenous CST ... Growth hormone (GH) and insulin-like growth factor-I (IGF-I) are essential factors in mammary-gland (MG) development and are ... circulating ghrelin and IGF-1, and pituitary GHRH and ghrelin receptor expression). Fasting increased corticosterone levels in ... This review focuses on the role of the Melanin-Concentrating Hormone (MCH) and receptors on memory formation in animal studies ...
  https://med.stanford.edu/profiles/luis-de-lecea
*  中国科技论文在线
Analysis of Ghrelin and growth hormone secretagogue receptor expressions in mouse thymic epithelial cells. ... Results identified that the mRNA of Ghrelin and GHS-R can be detected in MTEC1 cells. The protein levels of GHS-R and ghrelin ... The results of western blot analysis make sure that GHS-R and precursor of ghrelin are expressing in MTEC1 cells. GHS-R is a ... The present study was to identified the expression of Ghrelin and GHS-R in mouse thymic medullary-type epithelial cells (MTEC1 ...
  http://www.paper.edu.cn/releasepaper/search?searchType=0&searchContent=South%20China
*  Table of Contents | Diabetes
Genetic Linkage and Association of the Growth Hormone Secretagogue Receptor (Ghrelin Receptor) Gene in Human Obesity Andrea ... Growth Hormone Overexpression in the Central Nervous System Results in Hyperphagia-Induced Obesity Associated With Insulin ... Insulin Deficiency Downregulated Heat Shock Protein 60 and IGF-1 Receptor Signaling in Diabetic Myocardium Harn-Shen Chen, Yue- ... Increased Glucocorticoid Receptor and 11β-Hydroxysteroid Dehydrogenase Type 1 Expression in Hepatocytes May Contribute to the ...
  http://diabetes.diabetesjournals.org/content/54/1
*  GHSR Gene - GeneCards | GHSR Protein | GHSR Antibody
Growth Hormone Secretagogue Receptor, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards ... Ghrelin is the endogenous ligand for the ghrelin receptor, also known as the growth hormone secretagog receptor (GHS-R1a). ... Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone ... Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=GHSR
*  The role of ghrelin in weight-regulation disorders: Implications in clinical practice | Springer for Research & Development
Ghrelin, an orexigenic protein with a unique lipid chain modification, is considered to be an important gut-brain signal for ... The ghrelin receptor, growth-hormone secretagogue receptor type 1a, is able to bind acylated ghrelin. The first recognised ... 2005 Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity. ... 2007 The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor. Cell ...
  https://rd.springer.com/article/10.14310%2Fhorm.2002.1551
*  Cortistatin Is Not a Somatostatin Analogue but Stimulates Prolactin Release and Inhibits GH and ACTH in a Gender-Dependent...
... binds ghrelin receptor growth hormone secretagogue receptor type 1a (GHS-R1a)]. To determine whether the role of endogenous CST ... Although CST has been considered as a natural SST-analogue acting through their shared receptors (SST receptors 1-5), emerging ... which were associated with an increase in stomach ghrelin/ghrelin O-acyl transferase expression. Finally, CST deficit uncovered ... Also, CST effects on hormone expression/secretion were evaluated in primary pituitary cell cultures from male/female mice and ...
  https://insights.ovid.com/endoc/201112000/00003571-201112000-00035
*  Frontiers | Hunger and Satiety Gauge Reward Sensitivity | Endocrinology
... and ghrelin - enhance the sensitivity of the dopaminergic reward system. Then, we will elaborate how mediators of satiety - the ... and ghrelin - enhance the sensitivity of the dopaminergic reward system. Then, we will elaborate how mediators of satiety - the ... Many of the neurocircuits and hormones known to underlie the sensations of hunger and satiety also substantially alter the ... Many of the neurocircuits and hormones known to underlie the sensations of hunger and satiety also substantially alter the ...
  https://www.frontiersin.org/articles/10.3389/fendo.2017.00104/full
*  pralmorelin | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
It is an analogue of [Met]enkephalin and activates the growth hormone secretagogue (ghrelin) receptor.. ... growth hormone-releasing peptide 2, GHRP-2) is an orally-active, synthetic peptide drug which acts as a growth hormone ...
  http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1092
*  Screening Gene Knockout Mice for Variation in Bone Mass: Analysis by μCT and Histomorphometry | Springer for Research &...
Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor. J Clin Endocrinol Metab. 2009;94(11):4334- ... A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet. ... Carroll SH, Wigner NA, Kulkarni N, Johnston-Cox H, Gerstenfeld LC, Ravid K. A2B adenosine receptor promotes mesenchymal stem ... The effects of parathyroid hormone peptides on the peripheral skeleton of postmenopausal women. A systematic review. Bone. 2017 ...
  https://rd.springer.com/article/10.1007/s11914-018-0421-4
*  Adenosine - Wikipedia
Adenosine is an endogenous agonist of the ghrelin/growth hormone secretagogue receptor. However, while it is able to increase ... Adenosine receptor Adenosine reuptake inhibitor List of growth hormone secretagogues I.K. Morton; Judith M. Hall (6 December ... appetite, unlike other agonists of this receptor, adenosine is unable to induce the secretion of growth hormone and increase ... The A1 receptors couple to Gi/o and decreases cAMP levels, while the A2 adenosine receptors couple to Gs, which stimulates ...
  https://en.wikipedia.org/wiki/Adenosine
*  GHRP-6 - steroid.com
... mimic the production of ghrelin. This mode of action stimulates the ghrelin receptors, GHS-R1a or Growth Hormone Secretagogue. ... GHRP-6 (Growth Hormone Releasing Hexapeptide) is a peptide hormone of the Growth Hormone (GH) class. The purpose of GHRP-6 as ... If another Growth Hormone Releasing Hormone (GHRH) is used, such as Mod GRF 1-29, the total amount of GHRP-6 needed will be ... Alternatively, the hormone will promote fat loss and more importantly enhance the rate of recovery. However, while ghrelin has ...
  https://www.steroid.com/GHRP-6.php
*  Protocols and Video Articles Authored by Kenji Saito (Translated to German)
The ghrelin receptor, growth hormone secretagogue receptor (GHS-R), is highly expressed in the brain and detectable in some ... Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-Induced Obesity Diabetes. Aug, 2016 , Pubmed ID: 27207529 ... Rapid Increase in Fibroblast Growth Factor 21 in Protein Malnutrition and Its Impact on Growth and Lipid Metabolism The British ... Rapid Increase in Fibroblast Growth Factor 21 in Protein Malnutrition and Its Impact on Growth and Lipid Metabolism - ERRATUM ...
  https://www.jove.com/author/Kenji_Saito?language=German
*  Anti-Human GHRL scFv Stable Cell Line-CHO CSC-P0769 - Creative BioMart
... ghrelin receptor binding; growth hormone-releasing hormone activity; growth hormone-releasing hormone activity; growth hormone- ... Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the ... GHRL; ghrelin/obestatin prepropeptide; ghrelin, growth hormone secretagogue receptor ligand; appetite-regulating hormone; ... ghrelin; MTLRP; obestatin; motilin-related peptide; growth hormone secretagogue; ghrelin/obestatin preprohormone; growth ...
  https://www.creativebiomart.net/description_174126_309.htm
*  С ?? ҩ ??.??Ϣ?? .11256001??11256500
11256215:Genetic Linkage and Association of the Growth Hormone Secretagogue Receptor(Ghrelin Receptor) Gene in Human Obesity ... 11256225:Growth Hormone Overexpression in the Central Nervous System Results in Hyperphagia-Induced Obesity Associated With ... 11256042:Soluble Vascular Endothelial Growth Factor Receptor-1(sFLT-1) Mediates Downregulation of FLT-1 and Prevents Activated ... 11256248:Coligation of the B Cell Receptor with Complement Receptor Type 2(CR2/CD21) Using Its Natural Ligand C3dg: Activation ...
  http://www.100md.com/index/other/byinfono/022/513.htm
*  Growth hormone receptor - Wikipedia
This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor ... and growth hormone receptor (GHR) expression by growth hormone (GH) in mouse liver." Growth Horm IGF Res 17(2): 104-112. ... receptor complex. • integral component of plasma membrane. • extracellular region. • cell surface. • growth hormone receptor ... cellular response to hormone stimulus. • growth hormone receptor signaling pathway. • activation of MAPK activity. • taurine ...
  https://en.wikipedia.org/wiki/Growth_hormone_receptor
*  Motilin - Wikipedia
Ghrelin stimulates growth hormone secretagogue receptors in the pituitary. These receptors are distinct from the growth hormone ... Growth hormone secretagogue receptors share 52% of their DNA with motilin receptors, and agonists of these receptors, termed ... This domain is also found in ghrelin, a growth hormone secretagogue synthesised by endocrine cells in the stomach. ... hormone receptors, and, thus, provide a means of controlling pituitary growth hormone release by the gastrointestinal system. ...
  https://en.wikipedia.org/wiki/Motilin
*  Recombinant Human Ghrelin/Obestatin Prepropeptide GHRL-179H - Creative BioMart
Recombinant human Ghrelin protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 12.8 ... ghrelin, growth hormone secretagogue receptor ligand; ghrelin; Appetite-regulating hormone; M46 protein; Growth hormone ... Neuroactive ligand-receptor interaction. Function:. ghrelin receptor binding; growth hormone-releasing hormone activity; ... Ghrelin, also known as Obestatin, is the ligand for growth hormone secretagogue receptor type 1 (GHSR). It induces the release ...
  https://www.creativebiomart.net/description_6685_7.htm
*  Growth Hormone News, Research
AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice Scientists have ... Growth Hormone News and Research. RSS Growth hormone (GH) is a protein-based peptide hormone. It stimulates growth, cell ... Researchers have found a mutation in the gene for the growth hormone receptor that promotes longevity, increasing men's ... Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by the somatotroph cells ...
  https://www.news-medical.net/?tag=/Growth+Hormone
*  Macimorelin - Wikipedia
Macimorelin is a growth hormone secretagogue receptor (ghrelin receptor) agonist causing release of growth hormone from the ... Koch, Linda (2013). "Growth hormone in health and disease: Novel ghrelin mimetic is safe and effective as a GH stimulation test ... List of growth hormone secretagogues "Aeterna Zentaris NDA for Macimorelin Acetate in AGHD Accepted for Filing by the FDA". ... Macimorelin (INN) is a drug being developed by Æterna Zentaris for use in the diagnosis of adult growth hormone deficiency. As ...
  https://en.wikipedia.org/wiki/Macimorelin
*  Patents | Neogen
Polymorphisms in Growth Hormone Receptor, Ghrelin, Leptin, Neuropeptide Y, and Uncoupling Protein 2 Genes and Their ... Associations of Polymorphisms in the Fibroblast Growth Factor 8 (FGF8) and its Haplotypes with Carcass Quality, Growth and Feed ... Microbial Growth Detector. 2011/0275112. Optical Method and Device for the Detection and Enumeration of Microorganisms. 2014/ ... Urotensin 2 and its Receptor as Candidate Genes for Beef Marbling Score, Ribeye Area and Fatty Acid Composition. 7,955,803. ...
  http://www.neogen.com/sp/patents
*  Frontiers | Brain Circuits Mediating the Orexigenic Action of Peripheral Ghrelin: Narrow Gates for a Vast Kingdom |...
Our group studies the neuronal circuitries and molecular mechanisms by which the stomach-produced hormone ghrelin regulates ... The study of the mechanisms by which hormones act in the brain in order to regulate specific neuronal populations is a research ... brain targets of peripheral ghrelin is essential for the comprehensive understanding of the physiological role of this hormone ... Brain Circuits Mediating the Orexigenic Action of Peripheral Ghrelin: Narrow Gates for a Vast Kingdom ...
  https://www.frontiersin.org/articles/10.3389/fendo.2015.00044/full
*  The Prokinetic Face of Ghrelin
... ghrelin secretagogue receptor 6 (non-synthetic ghrelin receptor agonist); GHS-R: growth hormone secretagogue receptor; h: hour ... ghrelin secretagogue receptor 6 (non-synthetic ghrelin receptor agonist); GHS-R: growth hormone secretagogue receptor; IV: ... showed that ghrelin and ghrelin receptor synthetic peptide agonist, growth hormone receptor peptide 6 (GHRP-6), enhanced off- ... Being the ligand of growth hormone secretagogue receptor, ghrelin has been shown to induce growth hormone secretion [53] and ...
  https://www.hindawi.com/journals/ijpep/2010/493614/
*  Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease | Journal of...
2007) Ghrelin and growth hormone secretagogue receptor expression in mice during aging. Endocrinology 148:1323-1329, doi: ... 2004) Alterations in stomach ghrelin production and in ghrelin-induced growth hormone secretion in the aged rat. Mech Ageing ... growth hormone secretagogue receptor 1a (GHSR)] in the brain. In addition to its well known metabolic effects, ghrelin is ... 2010) Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice. Proc Natl ...
  http://www.jneurosci.org/content/36/10/3049
*  Ghrelin in Female and Male Reproduction
Ghrelin and one of its functional receptors, GHS-R1a (Growth Hormone Secretagogue Receptor 1a), were firstly studied about 15 ... Ghrelin could be a component of the complex series of nutrient sensors such as adipokines, and nuclear receptors, which ... Ghrelin is a multifunctional peptide hormone that affects several biological functions including food intake, glucose release, ... Ghrelin in Female and Male Reproduction. Joëlle Dupont, Virginie Maillard, Stéphanie Coyral-Castel, Christelle Ramé, and Pascal ...
  https://www.hindawi.com/journals/ijpep/2010/158102/abs/