*  Functional Correlation of Trophinin Expression with the Malignancy of Testicular Germ Cell Tumor | Cancer Research
Testicular germ cell tumor is one of the few neoplasms associated with accurate serum marker, hCG (6) . The hCG is found in the ... 5) ⇓ . Clinical data of the testicular germ cell tumors (Table 1) ⇓ showed that testicular germ cell tumors metastasize to the ... Human Testicular Germ Cell Tumor Specimens.. Testicular germ cell tumor specimens from 158 patients (76 seminoma and 82 ... Immunohistochemistry of human testicular germ cell tumors. Paraffin sections of testicular germ cell tumors were stained with ...
  http://cancerres.aacrjournals.org/content/64/12/4257
*  Treatment of stage II seminoma
... although these tumors only account for approximately 1 percent of all cancers in men. Germ cell tumors (GCTs), which account ... Testicular cancer is the most common solid malignancy affecting males aged 15 to 35 years, ... Germ cell tumors (GCTs), which account for 95 percent of testicular cancers, are one of the most curable solid neoplasms due to ... Initial risk-stratified treatment for advanced testicular germ cell tumors. *Overview of the treatment of testicular germ cell ...
  https://www.uptodate.com/contents/treatment-of-stage-ii-seminoma
*  Germ Cell Origin of Testicular Carcinoid Tumors | Clinical Cancer Research
... a germ cell neoplasm that shares the same clonal origin with coexisting germ cell tumors, including embryonal carcinoma, yolk ... Germ Cell Origin of Testicular Carcinoid Tumors Message Subject (Your Name) has forwarded a page to you from Clinical Cancer ... The cell type giving rise to testicular carcinoid is unknown. We hypothesized that testicular carcinoid may have a germ cell ... testicular carcinoid tumors for the presence of a chromosomal abnormality commonly present in testicular germ cell tumors, and ...
  http://clincancerres.aacrjournals.org/content/14/5/1393.long
*  Daniel C. Cho | NYU Langone Health
kidney cancer, testicular cancer, male germ cell tumor, urinary tract cancer, genitourinary neoplasm, renal cell carcinoma ... Axitinib in combination with pembrolizumab in patients (pts) with advanced renal cell carcinoma (aRCC): Preliminary safety and ... IN PATIENTS WITH SELECT LOCALLY ADVANCED OR METASTATIC SOLID TUMOR MALIGNANCIES. ... in Locally Advanced/Metastatic Renal Cell Carcinoma (mRCC) (KEYNOTE-427). ...
  https://nyulangone.org/doctors/1750306783/daniel-c-cho
*  Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer - Full Text View -...
Pancreatic Neoplasms. Neoplasms, Germ Cell and Embryonal. Skin Neoplasms. Testicular Neoplasms. Duodenal Neoplasms. Ileal ... skin cancer. small intestine cancer. pancreatic cancer. malignant testicular germ cell tumor. testicular teratoma. ... Non-melanomatous Skin Cancer Pancreatic Cancer Small Intestine Cancer Testicular Germ Cell Tumor Genetic: in situ hybridization ... Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer. This study has been ...
  https://clinicaltrials.gov/ct2/show/NCT00899132?recr=Open&cond=%22Duodenal+Neoplasms%22&rank=9
*  Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer - Full Text View -...
Pancreatic Neoplasms. Neoplasms, Germ Cell and Embryonal. Skin Neoplasms. Testicular Neoplasms. Intestinal Neoplasms. Duodenal ... skin cancer. small intestine cancer. pancreatic cancer. malignant testicular germ cell tumor. testicular teratoma. ... Non-melanomatous Skin Cancer Pancreatic Cancer Small Intestine Cancer Testicular Germ Cell Tumor Genetic: in situ hybridization ... Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer. The safety and ...
  https://clinicaltrials.gov/ct2/show/NCT00899132
*  Chapter 96. Testicular Cancer | Harrison's Principles of Internal Medicine, 18e | AccessPharmacy | McGraw-Hill Medical
Primary germ cell tumors (GCTs) of the testis arising by the malignant transformation of primordial germ cells constitute 95% ... of all testicular neoplasms. Infrequently, GCTs arise from an extragonadal site, including the mediastinum, retroperitoneum, ... A painless testicular mass is pathognomonic for a testicular malignancy. More commonly, patients present with testicular ... Testicular Cancer." Harrison's Principles of Internal Medicine, 18e Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, ...
  http://accesspharmacy.mhmedical.com/content.aspx?bookid=331§ionid=40726832
*  Endodermal sinus tumor - Wikipedia
... also known as yolk sac tumor (YST), is a member of the germ cell tumor group of cancers. It is the most common testicular tumor ... Before modern chemotherapy, this type of neoplasm was highly lethal, but the prognosis has significantly improved since. When ... Germ cell tumor Testicular cancer Luther N, Edgar MA, Dunkel IJ, Souweidane MM (Aug 2006). "Correlation of endoscopic biopsy ... adult endodermal sinus tumors are often found in combination with other kinds of germ cell tumor, particularly teratoma and ...
  https://en.wikipedia.org/wiki/Endodermal_sinus_tumor
*  Mediastinal germ cell tumor - Wikipedia
The treatment for mediastinal nonseminomatous germ cell tumors should follow guidelines for poor-prognosis testicular cancer. ... They are much less common than germ cell tumors arising in the testes, and account for only 1 to 5% of all germ cell neoplasms ... Primary Germ Cell Tumors of the Thorax Malignant Mediastinal Germ Cell Tumors Knapp RH, Hurt RD, Payne WS, et al. Malignant ... Mediastinal germ cell tumors are tumors that derive from germ cell rest remnants in the mediastinum. They most commonly occur ...
  https://en.wikipedia.org/wiki/Mediastinal_germ_cell_tumor
*  Testicular Cancer | Harrison's Principles of Internal Medicine, 19e | AccessMedicine | McGraw-Hill Medical
Germ Cell Cancer and Multiple Relapses: Toxicity and Survival.. Pediatric germ cell tumors from 1987 to 2011: incidence rates, ... of the testis arising by the malignant transformation of primordial germ cells constitute 95% of all testicular neoplasms. ... Personalised chemotherapy based on tumour marker decline in poor prognosis germ-cell tumours (GETUG 13): a phase 3, multicentre ... A painless testicular mass is pathognomonic for a testicular malignancy. More commonly, patients present with testicular ...
  http://accessmedicine.mhmedical.com/content.aspx?sectionid=71749184&bookid=1130&jumpsectionID=71749184
*  Improving Treatment of Germ Cell Tumors | ASCO Annual Meeting
Prognosis for men with newly diagnosed germ cell tumors is generally excellent; at present, more than 90% of these men will be ... testicular cancer survivors are at increased risk of other solid tumors for at least 35 years. ... With regard to neoplasms, as well as other problems in patients with germ cell tumors, Dr. Einhorn stressed that "we need to ... Improving Treatment of Germ Cell Tumors. Ethics. Improving Treatment of Germ Cell Tumors Share via Email Share on Twitter Share ...
  https://am.asco.org/node/1546
*  The Microenvironment of Germ Cell Tumors Harbors a Prominent Antigen-Driven Humoral Response | The Journal of Immunology
Although seminomas are the most common form of testicular cancer, dysgerminomas are relatively rare, as are intracranial ... Germ cell tumors are a heterogeneous group of neoplasms derived from residual primordial tissue. These tumors are commonly ... Like several other tumor types, including melanoma, sarcoma, colon cancer, and breast cancer (2), germ cell tumors are often ... Most germ cell tumors harbor a prominent immune cell infiltrate that includes substantial numbers of T and B cells. To assess ...
  http://www.jimmunol.org/content/182/5/3310
*  Clinical Response of a Patient to Anti-PD-1 Immunotherapy and the Immune Landscape of Testicular Germ Cell Tumors | Cancer...
A fine needle aspiration (FNA) demonstrated a malignant neoplasm of large epithelioid cells with high nuclear to cytoplasmic ... Gene expression heatmap of non-T-cell-inflamed, intermediate, and T-cell-inflamed testicular germ cell tumors from TCGA. Genes ... Frequent PD-L1 expression in testicular germ cell tumors. Br J Cancer 2015;113:411-3. ... A prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group. ...
  http://cancerimmunolres.aacrjournals.org/content/4/11/903
*  Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation -...
Testicular Germ Cell Tumor. Intervention ICMJE Biological: peripheral blood lymphocyte therapy. Study Arms Not Provided. ... RATIONALE: White blood cells from donors may be able to kill cancer cells in patients with cancer that has recurred following ... Gestational Trophoblastic Tumor. *Kidney Cancer. *Leukemia. *Lymphoma. *Multiple Myeloma and Plasma Cell Neoplasm ... National Cancer Institute (NCI). Investigators ICMJE Study Chair:. Mary E. D. Flowers, MD. Fred Hutchinson Cancer Research ...
  https://clinicaltrials.gov/ct2/show/record/NCT00003887
*  Cancer cells, the DNA-ransackers - DocCheck News - DocCheck News
Cancers with few aberrations, for example, include testicular germ cell tumors and acute leukemias. Very many mutations, by ... Over time, cancer genome specialists have come to doubt that such a rule holds. In hematopoietic neoplasms usually only a few ... It was long regarded to be true of "cancer genes" that about five of them are altered when a proliferating tumor cell arises ... Why does a normal cell at some point become a cancer cell? In the course of its life, influences from within and without are ...
  http://news.doccheck.com/en/123/cancer-cells-the-dna-ransackers/
*  FOXL2 gene | Cancer Genetics Web
The term "human germ cell tumors" (GCTs) refers to a heterogeneous group of neoplasms, all with a defined histological ... Ovarian Cancer. FOXL2 and Ovarian Cancer. View Publications. 43. Testicular Cancer. FOXL2 and Testicular Cancer. View ... Extra-Hepatic Bile duct cancer (cholangiocarcinoma) Kidney Cancer Liver Cancer Cancer of the Pancreas Pancreatic Cancer ... proliferation of pLB cells in mixed-cell 3D colonies in vitro and that pLUM cells suppress growth of pLB cells in mixed-cell ...
  http://www.cancerindex.org/geneweb/FOXL2.htm
*  Renal Flashcards - Cram.com
What different cell types are involved with testicular cancer 95% are germ cell tumors: seminoma and nonseminoma. Rest are ... renal & bladder CA: extraglomerular: cysts, calculi, interstitial nephrities, renal neoplasms. Glomerular: IgA nephropathy, ... Describe age and clinical presentation of pt's with testicular tumors. Know that cryptorchidism is a risk factor! ... Name that incontinence! most common in elderly, leakage delayed seconds after stress, can result from bladder stones or tumor ...
  http://www.cram.com/flashcards/renal-439985
*  Regulation of transcription in cancer - Wikipedia
... in testicular and other germ cell tumors, and in Ewing's sarcoma, FEN1 is over-expressed in the majority of cancers of the ... Such mutations and epigenetic alterations can give rise to cancer (see malignant neoplasms). Thus, CpG island hyper/hypo- ... of non-small-cell lung cancers; promoter hypermetylation of ATM occurs in 47% of non-small-cell lung cancers; promoter ... of stomach cancers, 74% of thyroid cancers, 40%-90% of colorectal cancers and 50% of brain cancers. Promoter hypermethylation ...
  https://en.wikipedia.org/wiki/Regulation_of_transcription_in_cancer
*  Chapter 24. Genital Tumors | Smith & Tanagho's General Urology, 18e | AccessMedicine | McGraw-Hill Medical
... are germ cell tumors (seminoma and nonseminoma), while the remainders are nongerminal neoplasms (Leydig cell, Sertoli cell, ... Although the cause of testicular cancer is unknown, both congenital and acquired factors have been associated with tumor ... Seminoma is the most common germ cell tumor in bilateral primary testicular tumors, while malignant lymphoma is the most common ... Of primary testicular tumors, 1-2% are bilateral, and about 50% of these tumors occur in men with a history of unilateral or ...
  http://accessmedicine.mhmedical.com/content.aspx?bookid=508§ionid=41088101
*  What Is a Testicular Neoplasm? (with pictures)
The main signs of a testicular neoplasm are a painless lump... ... A testicular neoplasm is a type of abnormal growth in the ... a testicular neoplasm arises from what are known as germ cells, or reproductive cells. Most tumors develop in the cells that go ... while benign tumors are not. Most testicular tumors are cancerous but fortunately testicular cancer is not very common and ... Nonseminomas are tumors formed from other types of germ cell. A testicular neoplasm is most likely to develop in a white male ...
  http://www.wisegeek.com/what-is-a-testicular-neoplasm.htm
*  U.S. National Institutes of Health | Netdata
Plasma Cell Neoplasm,Myelodysplastic Syndromes,Neuroblastoma,Ovarian Cancer,Sarcoma,Testicular Germ Cell Tumor. Biological: ... Impact of OncoDoc2 on Guideline Compliance in the Management of Breast Cancer. Completed. No Results Available. Breast Cancer. ... Docetaxel and Cetuximab in Treating Patients With Metastatic Prostate Cancer. Completed. No Results Available. Prostate Cancer ... Breast Cancer,Graft Versus Host Disease,Kidney Cancer,Leukemia,Lymphoma,Mucositis,Multiple Myeloma, ...
  http://www.netdata.com/netsite/08750f34/us-national-institutes-of-health?p=4671
*  Campath-1H + FK506 and Methylprednisolone for GVHD - Full Text View - ClinicalTrials.gov
Ovarian Cancer Testicular Germ Cell Tumor Biological: alemtuzumab Drug: methylprednisolone Drug: tacrolimus Phase 2 ... Neoplasms, Germ Cell and Embryonal. Graft vs Host Disease. Plasmacytoma. Testicular Neoplasms. Myeloproliferative Disorders. ... Large-cell, Immunoblastic Hairy Cell Leukemia Ovarian Germ Cell Tumor Chronic Neutrophilic Leukemia Anaplastic Plasmacytoma ... Breast Neoplasms. Neoplasms. Multiple Myeloma. Neoplasms, Plasma Cell. Myelodysplastic Syndromes. Preleukemia. Neuroblastoma. ...
  https://clinicaltrials.gov/show/NCT00109993%A0
*  Seminoma - Wikipedia
Testicular seminoma originates in the germinal epithelium of the seminiferous tubules. About half of germ cell tumors of the ... It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered ... This is about 5 to 10 years older than men with other germ cell tumors of the testes. In most cases, they produce masses that ... Seminoma (also known as pure seminoma or classical seminoma) is a germ cell tumor of the testicle or, more rarely, the ...
  https://en.wikipedia.org/wiki/Seminoma
*  Testicular Granulosa Cell Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
testicular malignant germ cell cancer 10.4. CSH1 CSH2 8. lung benign neoplasm 10.4. CD99 WT1 ... Testicular Granulosa Cell Tumor family:. Juvenile Type Testicular Granulosa Cell Tumor Adult Type Testicular Granulosa Cell ... Articles related to Testicular Granulosa Cell Tumor:. id. Title. Authors. Year. 1. Adult testicular granulosa cell tumor: a ... MalaCards integrated aliases for Testicular Granulosa Cell Tumor:. Name: Testicular Granulosa Cell Tumor 12 14 69 ...
  http://www.malacards.org/card/testicular_granulosa_cell_tumor
*  Postersitzung 3: Der metastasierte Hodentumor - Probleme der Palliativtherapie urologischer Tumoren | Springer for Research &...
Peckham MJ, Barrett A, Husband A, Hendry WF (1982) Orchidectomy alone in testicular stage I nonseminomatous germ cell tumors. ... Williams SD, Einhorn LH (1979) Brain metastases in disseminated germinal neoplasms. Cancer 44: 1514-1516PubMedCrossRefGoogle ... Successful management of metastatic and primary germ cell tumors in the brain. Cancer 57: 2108-2113PubMedCrossRefGoogle Scholar ... Azer FC, Braunstein GD (1981) Malignant Leydig cell tumor response to op-DDD. Cancer 47: 1251-1255PubMedCrossRefGoogle Scholar ...
  https://rd.springer.com/chapter/10.1007/978-3-642-83404-2_20