Mucin expression in CF via IL-6, IL-17 signaling pathways
Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'- ... and these mucins are subject to regulation by CF inflammatory stimuli. Mucin 5AC and Mucin 5B have been identified as major gel ... Expression of Mucin 5AC and Mucin 5B in response to IL-17 has also been proposed to depend on JAK2/ STAT3 and ERK1/2 signaling ... Several transcription factors, including NF-kB, c-Jun/c-Fos and SP1, can be involved in Mucin 5AC and Mucin 5B transcription [2 ...http://pathwaymaps.com/maps/2655/
Mucin 4 - Wikipedia
2002). "Genomic organization of MUC4 mucin gene. Towards the characterization of splice variants". Eur. J. Biochem. 269 (15): ... Mucin 4 (MUC 4) is a mucin protein that in humans is encoded by the MUC4 gene. Like other mucins, MUC-4 is a high-molecular ... As a mucin, MUC-4 also alters adhesive properties of the cell. When overexpressed, the disorganization of mucins may reduce ... "Entrez Gene: MUC-4 mucin 4, cell surface associated". "MUC4 (mucin 4, cell surface associated)". Atlas of Genetics and ...https://en.wikipedia.org/wiki/Mucin_4
Mucin 20 - Wikipedia
... genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney". J Biol Chem. 279 ( ... "Entrez Gene: MUC20 mucin 20, cell surface associated". Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: ... Mucin-20 is a protein that in humans is encoded by the MUC20 gene. ENSG00000281630, ENSG00000277753, ENSG00000275501, ... 6 (9): 791-806. doi:10.1101/gr.6.9.791. PMID 8889548. Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding ...https://en.wikipedia.org/wiki/Mucin_20
Gel-forming mucins appeared early in metazoan evolution | PNAS
Twelve of the Muc5 and Muc2 proteins are localized to a contig covering 1.15 Mb of genomic sequence that seems to be related to ... Gel-Forming Mucins in Nonvertebrate Chordates.. We identified mucins and mucin-related proteins in a variety of vertebrates as ... Other proteins with shorter mucin domains, like IgA and several receptors, are not called mucins. The mucin domains often ... "NIDO-AMOP-VWD mucins" (or "MUC4′") for these categories of mucins that previously were listed under transmembrane mucins. ...https://www.pnas.org/content/104/41/16209
FVSU College of Agriculture, Family Sciences and Technology :: Joshee, Nirmal
Isolation and characterization of a water- stress specific genomic gene, pwsi18, from rice. Plant Cell Physiol. 39 (1): 64 -72. ... Development of monoclonal antibodies against bovine mucin core-2β-6 N-acetylglucosaminyltransferase. Glycoconjugate Journal 16 ...http://ag.fvsu.edu/index.php/directory/joshee-nirmal/
Interferon-induced transmembrane protein 1 (IFITM1) overexpression enhances the aggressive phenotype of SUM149 inflammatory...
Genomic profiling of inflammatory breast cancer: a review. Breast. 2014;23(5):538-45.View ArticlePubMedGoogle Scholar. ... dysfunction of mucin 1; high proliferation; tumor protein 53 mutations; and elevated angiogenesis . Despite these efforts, ... Genomic and expression analysis of microdissected inflammatory breast cancer. Breast Cancer Res Treat. 2013;138(3):761-72.View ... Notably, we also performed comparative genomic hybridization (CGH) analysis to assess DNA copy number changes for IFITM1 and ...https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-016-0683-7
Eric R Burrough | College of Veterinary Medicine
Emergence of porcine epidemic diarrhea virus in the United States: clinical signs, lesions, and viral genomic sequences. J Vet ... Comparison of lesion severity, distribution, and colonic mucin expression in pigs with acute swine dysentery following oral ... Comparison of lesion severity, distribution, and colonic mucin expression in pigs with acute swine dysentery following oral ... Vet Pathol 2014; 51(6): 1096-1108. Šperling D, Smola J, Čížek A, Burrough ER. Brachyspira hampsonii - a new causal agent of ...https://www.vetmed.iastate.edu/users/burrough
Durable coexistence of donor and recipient strains after fecal microbiota transplantation | Science
Genomic variation landscape of the human gut microbiome. Nature 493, 45-50 (2013). doi:10.1038/nature11711 pmid:23222524. ... Mucin dynamics and enteric pathogens. Nat. Rev. Microbiol. 9, 265-278 (2011). doi:10.1038/nrmicro2538 pmid:21407243. ... Mucin glycan foraging in the human gut microbiome. Front. Genet. 6, 81 (2015). pmid:25852737. ... Revealing the bacterial butyrate synthesis pathways by analyzing (meta)genomic data. MBio 5, e00889-14 (2014). doi:10.1128/mBio ...http://science.sciencemag.org/content/352/6285/586?ijkey=341c6961758348a153ea9d79f0d2f44d7e45d7f5&keytype2=tf_ipsecsha
List of sequenced bacterial genomes - Wikipedia
2004). "The complete genomic sequence of Nocardia farcinica IFM 10152". Proc. Natl. Acad. Sci. U.S.A. 101 (41): 14925-30. ... a dedicated intestinal mucin degrader, and its use in exploring intestinal metagenomes". PLoS One. 6 (3): e16876. Bibcode: ... 2001). "Complete genomic sequence of Pasteurella multocida, Pm70". Proc. Natl. Acad. Sci. U.S.A. 98 (6): 3460-5. Bibcode: ... 2005). "Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent". Nucleic Acids Res. 33 (22): ...https://en.wikipedia.org/wiki/List_of_sequenced_bacterial_genomes
Mucin 1 gene silencing inhibits the growth of SMMC-7721 human hepatoma cells through Bax-mediated mitochondrial and caspase-8...
DNA Ladder extraction kits were used to extract the genomic DNA of SMMC-7721, NC, MR1-C6 and MR1-D4 cells. The DNA ladder was ... Yuan, H., Wang, J., Wang, F., Zhang, N., Li, Q., Xie, F., Chen, T., Zhai, R., Wang, F., Guo, Y., Ni, W., Tai, G.'Mucin 1 gene ... Yuan, H., Wang, J., Wang, F., Zhang, N., Li, Q., Xie, F., Chen, T., Zhai, R., Wang, F., Guo, Y., Ni, W., Tai, G.'Mucin 1 gene ... Mucin 1 (MUC1) is an oncogene that has a crucial role in the pathogenesis and progression of the majority of epithelial ...https://spandidos-publications.com/mmr/12/5/6782
MUC4 Mucin Potentiates Pancreatic Tumor Cell Proliferation, Survival, and Invasive Properties and Interferes with Its...
Genomic organization of MUC4 mucin gene. Towards the characterization of splice variants. Eur J Biochem 2002;269:3637-44. ... Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin. Biochem J 1999;338:325-33. ... Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy. Br J Cancer 2004;91:1633-8. ... Developmental mucin gene expression in the human respiratory tract. Am J Respir Cell Mol Biol 1999;20:209-18. ...http://mcr.aacrjournals.org/content/5/4/309
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The Δku80 strains make functional genomic studies feasible on the single gene as well as on the genome scale1-4. Here, we ... mucin and free DNA. P. aeruginosa growth in ASM mimics growth during CF infections, with the formation of self-aggregating ... We present the first method that extracts and purifies genomic DNA from blood drawn in the new BD P100 tubes. We compare the ... The allelic ratio obtained for cDNA is normalized using that measured from genomic DNA, where the allelic ratio is expected to ...https://www.jove.com/visualize/abstract/22253717/orai1-genetic-polymorphisms-associated-with-susceptibility-atopic
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Genomic DNA was isolated and the N-, tandem repeat (TR), and C-terminal regions of MUC7 were amplified by PCR since MG2 is ... An unusual glycoform of human salivary mucin MG2.. Rodrigo V Soares, Gwynneth D Offner, Marina A L Assis, Karine C Silva, Elton ... Genomic DNA analysis showed that MUC7 in the individual with split MG2 bands was not truncated and that the MUC7 genotype in ... The MG2 split banding pattern observed in this subject was not derived from proteolytic degradation of this salivary mucin in ...https://www.jove.com/visualize?author=Rodrigo+P+P+Soares
May 2013 - Page 2 of 6 - Notch by NotchNotch by Notch | Page 2
Fortunately, A. muciniphila is good bacteria and is also fond of mucin (the main component of mucus) - thus the second part of ... "Polysaccharide Utilization by Gut Bacteria: Potential for New Insights from Genomic Analysis." Nature Reviews Microbiology 6, ... Nov., a Human Intestinal Mucin-degrading Bacterium." International Journal of Systematic and Evolutionary Microbiology 54, no. ... 6 (December 2003): 754-758. doi:10.1016/j.jpeds.2003.09.028.. Flint, Harry J., Edward A. Bayer, Marco T. Rincon, Raphael Lamed ...http://notchbynotch.com/2013/05/page/2/
Gcnt3 - Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 - Mus musculus (Mouse) - Gcnt3...
Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme ... Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. ... br>,/br>The component name refers to the genomic component encoding a set of proteins. ,br>,/br>These range from a single ... R-MMU-913709. O-linked glycosylation of mucins. Miscellaneous databases. ChiTaRS: a database of human, mouse and fruit fly ...http://www.uniprot.org/uniprot/Q5JCT0
Bocavirus infection may be associated with pneumonia in Thailand, especially i...( The newly identified human bocavirus wa...)
Mucins stand guard against gut infections. 7. Bernese Mountain Dogs prone to Borrelia burgdorferi infection. 8. New compound ... Date:10/7/2017)... WA (PRWEB) , ... October ... ... industry leader in Hi-C-based genomic technologies, launched its ProxiMeta ... 6] Socionext's New Media Edge Server with Codec Functionality Enables Expanded Video Data Utilization Solutions Global Eye ... Date:10/6/2017)... ... October 06, 2017 , ... The ... and technology sector at their fourth annual Conference where founders, ...http://news.bio-medicine.org/biology-news-3/Bocavirus-infection-may-be-associated-with-pneumonia-in-Thailand--especially-in-children-7637-1/
sialosyl-T antigen Summary Report | CureHunter
... a mucin-type antigen present in normal breast tissue & benign lesions; not diagnostic for malignant breast lesions ... Genomic Instability 07/01/2015 - "To investigate whether the small tumour (ST) antigen of the JCV contributes to genomic ... a mucin-type antigen present in normal breast tissue & benign lesions; not diagnostic for malignant breast lesions ...http://www.curehunter.com/public/keywordSummaryC087769-sialosyl-T-antigen.do
A potential role of probiotics in colorectal cancer prevention: review of possible mechanisms of action | SpringerLink
Kim J, Khan W (2013) Goblet cells and mucins: role in innate defense in enteric infections. Pathogens 2:55-70Google Scholar ... McCabe D, Caudill M (2005) DNA methylation, genomic silencing, and links to nutrition and cancer. Nutr Rev 63:183-195Google ... Caballero-Franco C, Keller K, De Simone C, Chadee K (2007) The VSL#3 probiotic formula induces mucin gene expression and ... Mack DR, Ahrne S, Hyde L, Wei S, Hollingsworth MA (2003) Extracellular muc3 mucin secretion follows adherence of Lactobacillus ...https://link.springer.com/article/10.1007/s11274-013-1499-6
CD164 - Wikipedia
1999). "Genomic analysis of a murine cell-surface sialomucin, MGC-24/CD164". Eur. J. Biochem. 265 (1): 466-72. doi:10.1046/j. ... Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play two key but opposing roles ... 1992). "A novel core protein as well as polymorphic epithelial mucin carry peanut agglutinin binding sites in human gastric ... "CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin ...https://en.wikipedia.org/wiki/CD164
CLEC11A - Wikipedia
Bannwarth S, Giordanengo V, Lesimple J, Lefebvre JC (January 1998). "Molecular cloning of a new secreted sulfated mucin-like ... Bannwarth S, Giordanengo V, Grosgeorge J, Turc-Carel C, Lefebvre JC (April 1999). "Cloning, mapping, and genomic organization ... 226 (1): 30-6. doi:10.1016/j.cellimm.2003.11.001. PMID 14746805. Hollenbeck ST, Sakakibara K, Faries PL, Workhu B, Liu B, Kent ... of the LSLCL gene, encoding a new lymphocytic secreted mucin-like protein with a C-type lectin domain: A new model of exon ...https://en.wikipedia.org/wiki/CLEC11A
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
A preclinical model of invasive bladder cancer was developed in human mucin 1 (MUC1) transgenic (MUC1.Tg) mice for the purpose ... genomic DNA isolation from whole blood, and fetal DNA extraction and enrichment from large volumes of maternal plasma ( ... To induce bladder cancer, C57BL/6 mice (MUC1.Tg and wild type) were treated orally with the carcinogen N-butyl-N-(4- ... Tumors begin to appear 6 weeks after the initiation of oncogenic events. After tumors become apparent, they progress slowly for ...https://www.jove.com/visualize/abstract/22427815/molecular-prognostic-prediction-for-locally-advanced-nasopharyngeal
Critical roles of mucin-1 in sensitivity of lung cancer cells to tumor necrosis factor-alpha and dexamethasone | Springer for...
Mucins are glycoproteins with high molecular weight, responsible for cell growth, differentiation, and signaling, and were ... Wang DC, Shi L, Zhu Z, Gao D, Zhang Y. Genomic mechanisms of transformation from chronic obstructive pulmonary disease to lung ... Lung cancer Mucin-1 Tumor necrosis factor-alpha Dexamethasone Therapeutics This is a preview of subscription content, log in to ... Critical roles of mucin-1 in sensitivity of lung cancer cells to tumor necrosis factor-alpha and dexamethasone. ...https://rd.springer.com/article/10.1007/s10565-017-9393-x
GCNT3 - Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 - Bos mutus grunniens (Wild yak)...
Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme ... Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. ... AF465336 Genomic DNA. Translation: AAO22163.1.. 3D structure databases. Protein Model Portal of the PSI-Nature Structural ... Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme ...http://www.uniprot.org/uniprot/Q866Z5
VCFtoTree: a user-friendly tool to construct locus-specific alignments and phylogenies from thousands of anthropologically...
Xu D, Pavlidis P, Thamadilok S, Redwood E, Fox S, Blekhman R, Ruhl S, Gokcumen O. Recent evolution of the salivary mucin MUC7. ... The only input needed from users is the species and populations of interest, as well as the target genomic region. VCFtoTree ... One particular problem is to create manageable alignment files for loci of interest from whole genomic datasets to be compared ... We use a similar strategy to fetch and parse single nucleotide variants from ancient hominin genomic variants that are ...https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-017-1844-0
Olivera J. Finn, PhD | Department of Immunology | University of Pittsburgh
We were the first to identify a human tumor antigen recognized by human T cells and antibodies, the epithelial mucin MUC1. We ... Using genomic and bioinformatics approaches, we are defining a gene expression signature that characterizes individuals with ... Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms. Cancer Immunol ... Cancer Prev Res (Phila) 6:18-26.. Cascio, S., L. Zhang, and O. J. Finn. 2011. MUC1 protein expression in tumor cells regulates ...http://immunology.medicine.pitt.edu/graduate/person/olivera-j-finn-phd