*  Genome Sequence of Human Rhinovirus A22, Strain Lancaster/2015 - Semantic Scholar
The assembled genome is 8.7% divergent from the HRV-A22 reference strain over its full length, and it is only the second full- ... length genome sequence for HRV-A22. The new strain is designated strain HRV-A22/Lancaster/2015. ... The genome of human rhinovirus A22 (HRV-A22) was assembled by deep sequencing RNA samples from nasopharyngeal swabs. ... Viral and bacterial infection in acute asthma and chronic obstructive pulmonary disease increases the risk of readmission.. * ...
  https://www.semanticscholar.org/paper/Genome-Sequence-of-Human-Rhinovirus-A22-Strain-Lan-Atkinson-Bishop/b01a4f22fd90ac27402ac4cb8f7550f10c61212d
*  An expanded taxonomy of hepatitis C virus genotype 6: Characterization of 22 new full-length viral genomes. - Oxford...
With these 22 new genomes, HCV-6 now has a diverse and extended taxonomic structure, comprised of 28 assigned subtypes (denoted ... 6a-6xe) and 27 unassigned lineages, all of which have been represented by full-length genomes. Our phylogenetic analyses also ... We characterized the full-length genomes of 22 hepatitis C virus genotype 6 (HCV-6) isolates: 10 from Vietnam (classified into ... Full-length genome, Genotype 6, HCV, Laos, Sequence, Animals, China, Genetic Variation, Genome, Viral, Genotype, Hepacivirus, ...
  https://www.neuroscience.ox.ac.uk/publications/504606
*  Matt Gethers/20.380 HIV Project/Design Pitch - OpenWetWare
Red blood cells are ideal for this application because they lack a genome and thus cannot support viral replication. To mediate ... Plan is to introduce a permanent viral sink to patients. *Rather than trying to inhibit a part of the viral lifecycle through a ... These manipulated red blood cells act as viral sinks to deplete the viral load. ... but incapable of supporting viral replication. These cells would then act as viral "sinks." If you put enough of these in the ...
  https://openwetware.org/wiki/Matt_Gethers/20.380_HIV_Project/Design_Pitch
*  Publications | Institute Of Tropical & Infectious Diseases(UNITID)
Analysis of both viral diversity and intersubtype recombination would benefit from the sequencing of entire viral genomes ... Subject ML415 was infected with a viral genome identified as entirely subtype D. Two subjects displayed HIV-1 genomes that were ... including recombinant genomes in circulating viral particles. Nairobi sex workers, who are exposed to a range of viral strains ... The results showed that five out of the nine tested samples returned positive for presences PPR viral genome. This study has ...
  http://unitid.uonbi.ac.ke/uon_publications/author/4139
*  Microbiology Society Journals | Comparative analysis of the full genome sequence of European bat lyssavirus type 1 and type 2...
The lengths of each complete viral genome for EBLV-1 and EBLV-2 were 11 966 and 11 930 base pairs, respectively, and follow the ... standard rhabdovirus genome organization of five viral proteins. Comparison with other lyssavirus sequences demonstrates ... The lengths of each complete viral genome for EBLV-1 and EBLV-2 were 11 966 and 11 930 base pairs, respectively, and follow the ... Auewarakul, P. ( 2005 ). Composition bias and genome polarity of RNA viruses. Virus Res 109, 33-37.[CrossRef] ...
  http://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.82692-0
*  Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated...
Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated ... Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated ... To identify viral genomic elements responsible for the viral load, we investigated samples from a population of Irish women who ... Publication date & source: 2005-11, J Viral Hepat., 12(6):594-603.. In hepatitis C virus (HCV) infection, serum viral load is ...
  http://www.druglib.com/abstract/it/itakura-j_j-viral-hepat_20051100.html
*  gb4gv: A genome browser for geminivirus [PeerJ Preprints]
Currently, NCBI Viral Genome website is a popular repository of viral genomes that conveniently provides researchers a ... However, unlike the genome of living organisms, viral genomes most often maintain peculiar characteristics that fit into no ... By imposing a unified annotation scheme on the myriad of viral genomes may downplay their hallmark features. For example, ... But, the two bipartite genomes are kept separately in NCBI with no explicit association in linking them. Thus, our goal is to ...
  https://peerj.com/preprints/2705/
*  New Research on Inherited Herpesvirus May Have Implications for Transplantation
The Leicester study found that in people with CI-HHV-6, the viral genome is intact (has all of the genes required to reactivate ... This facilitates release of the viral genome. Dr Royle proposes that the virus uses normal telomere processes to escape from ... either through viral reactivation or through the effect on the telomere. Until further research is conducted to determine ... and are more susceptible to viral reactivation. The implications of the study suggested screening donors for this inherited ...
  http://www.infectioncontroltoday.com/news/2013/09/new-research-on-inherited-herpesvirus-may-have-implications-for-transplantation.aspx
*  Allele‐specific silencing therapy for Dynamin 2‐related dominant centronuclear myopathy | EMBO Molecular Medicine
Viral genome quantification. Transduction efficacy was evaluated through quantification of viral genomes in injected muscles. ... Quantification of the viral genomes (vg) in mice injected with AAV‐muSEAP (n ≥ 6). *P , 0.05, **P , 0.01, two‐tailed Mann- ... Quantification of the viral genomes (vg) in mice injected with AAV‐sh or control (n = 4). Non‐injected WT muscles were included ... AAVs were injected intramuscularly at 1011 viral genomes (vg)/TA muscle of HTZ KI‐Dnm2 mice at 1 month of age, and muscle ...
  http://embomolmed.embopress.org/content/early/2017/12/15/emmm.201707988
*  PPT - CHAPTER 1 9 PowerPoint Presentation - ID:1899836
A. General Features of Viral Reproductive Cycles. *Once a viral genome has entered a cell, the cell begins to manufacture viral ... The RNA molecules function both as mRNA for synthesis of viral proteins and as genomes for new virus particles released from ... The lysogenic cycle replicates the phage genome without destroying the host. *The viral DNA molecule is incorporated into the ... Candidates for the source of viral genomes are plasmids, circular DNA in bacteria and yeasts, and transposons, small mobile DNA ...
  https://www.slideserve.com/keegan/chapter-1-9
*  Biomolecules | Free Full-Text | Functional Aspects of PARP1 in DNA Repair and Transcription | HTML
... and viral replication can favor one function while suppressing the other. ... Table 3. PARP1 binding motifs identified in oncogenic viral genomes.. Oncogenic virus. Gene or DNA element. Motif. ... the large amounts of viral DNA produced act as template to support further viral replication while concurrently inhibiting ... Viral DNA-PARP1 interaction has already been shown to be important for enhancing replication of the human T-cell leukemia virus ...
  http://mdpi.com/2218-273X/2/4/524/htm
*  Patent US7074590 - Chimeric promoters - Google Patents
Modification of virus tropism and host range by viral genome shuffling. WO1999023236A1. 23 Oct 1998. 14 May 1999. Diversa ... USA 84:7413-7414), as well as use of viral vectors (e.g., adenoviral (see, e.g., Berns et al. (1995) Ann. NY Acad. Sci. 772:95- ... Liberated viral DNA was extracted four times by gently rocking with an equal volume of phenol and chloroform (1:1; vol:vol). ... Purification of Viral DNA. Virus-containing supernatants were layered onto a sorbitol cushion (20% D-sorbitol, 50 mM Tris [pH ...
  http://www.google.co.uk/patents/US7074590
*  Prevention of Measles, Rubella, Congenital Rubella Syndrome, and Mumps, 2013
Subacute sclerosing panencephalitis in an infant: diagnostic role of viral genome analysis. Ann Neurol 1994;36:103-8. ... 2Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, CDC ... Detection by polymerase chain reaction of wild-type measles virus genome in the cerebrospinal fluid of a patient with SSPE who ... Molecular analysis of measles virus genome derived from SSPE and acute measles patients in Papua, New Guinea. J Med Virol 2002; ...
  https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6204a1.htm?s_cid=rr6204a1_w
*  Provirus - Wikipedia
... the provirus may be activated and begin transcription of its viral genome. This can result in the destruction of its host cell ... All families of bacterial viruses with circular (single-stranded or double-stranded) DNA genomes or replicating their genomes ... all descendants of the infected cell will also bear proviruses in their genomes. This is known as lysogenic viral reproduction ... or a state that persists over longer periods of time as either inactive viral infections or an endogenous viral element. In ...
  https://en.wikipedia.org/wiki/Provirus
*  Frontiers | Kaposi's Sarcoma-Associated Herpesvirus Genome Replication, Partitioning, and Maintenance in Latency | Microbiology
Among the latently expressing viral factors, LANA seems to play pivotal roles in viral genome replication, partitioning, and ... Among the latently expressing viral factors, LANA seems to play pivotal roles in viral genome replication, partitioning, and ... The viral genome replicates according to the host cell cycle by recruiting the host cellular replication machinery. ... On the other hand, there are few reports about the partitioning and maintenance of the viral genome. It has been reported that ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2012.00007/full
*  Viral Infection of the Myocardium in Endocardial Fibroelastosis | Circulation
In 90% of samples, the viral genome was amplified; ,70% of the samples were positive for mumps viral RNA, while 28% amplified ... Defective viral genomes. In: Fields BN, Knipe DM, eds. Fundamental Virology. New York, NY: Raven Press; 1990:151-165. ... Both patients who were positive by PCR for either CMV or enterovirus also amplified a second viral genome (ie, mumps). However ... The link between viral myocarditis and EFE, therefore, supports a role for chronic viral infection in the etiology of EFE.5 ...
  http://circ.ahajournals.org/content/95/1/133
*  Lentiviral Vectors in Gene Therapy
Lentiviruses are a family of retroviruses capableof inserting their genome into the genetic material of dividing and ... integration of viral genome into host DNA; 7, generation of multiply spliced viral transcripts; 8, production of viral ... production of viral structural and replication proteins on polysomes; 15, transport of viral Env protein to cell membrane and ... budding of immature viral particle from cell surface; 18, maturation of virion into infectious particle mediated by viral ...
  http://www.els.net/WileyCDA/ElsArticle/refId-a0005742.html
*  Stealth Virus Infected Children: Brain Damage and the Development of Chronic Fatigue Syndrome and Fibromyalgia
The question that arose was how could such a fragmented viral genome, lacking certain viral genes while over expressing other ... Genetic instability and fragmentation of a stealth viral genome. Pathobiology. 1996;6:9-17. 12. Martin WJ. Cellular sequences ... Other regions of the cytomegaloviral genome are unevenly distributed, with certain viral genes being markedly over represented ... The virus has a fragmented viral genome (11). While the various fragments cover extensive regions of a typical cytomegalovirus ...
  http://www.prohealth.com/library/showarticle.cfm?libid=8409
*  Ebola Virus | Smore Newsletters
Viral genome replicates every time host nucleus divides.. · Host cell remains viable as long as the viral genome remains in ... Viral genome gets incorporated into specific sites of host cell chromosome.. ...
  https://www.smore.com/9062v
*  Lecture 14 - Virus Overview Flashcards by Kyle Tuttle | Brainscape
4.Viral genome is exposed and replication of viral protein structures and genome occurs. 5.New viral particles begin to ... 3.Chronic, Non-Lytic (infected cells slowly release viral progeny without cell death). 4.Latent (virus genome become integrated ... Growth period: Constituents are assembled into many complete viral particles, the total number of which equal the yield ...
  https://www.brainscape.com/flashcards/lecture-14-virus-overview-2937479/packs/4774517
*  CVC2 - Capsid vertex component 2 - Human herpesvirus 8 type P (isolate GK18) (HHV-8) - CVC2 gene & protein
... assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the ... Capsid vertex-specific component that plays a role during viral DNA encapsidation, ... Host-virus interaction, Viral genome packaging, Viral penetration into host nucleus, Viral release from host cell, Virus entry ... assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the ...
  http://www.uniprot.org/uniprot/Q2HRB3
*  OpenHelix: CMR
Viral Genomes at NCBI: Viral genome resources including single-stranded or double-stranded RNA or DNA viruses ... Genome Databases (prok + viral) : Genomic databases or repositories primarily aimed at prokaryotic or viral organisms. Some may ... VBRC: The Viral Bioinformatics Resource Center. UCSC Archaeal Genome Browser: Provides you with many research and analysis ... Containing over 400 genomes (and more than a gigabase of DNA sequence), CMR is a treasure-trove of microbial genome information ...
  http://www.openhelix.com/cgi/tutorialInfo.cgi?id=36
*  Biology News
Seven WKU students were part of a nationwide effort to investigate viral diversity by sequencing and analyzing the genomes of ... WKU Students Publish Analysis of Newly Sequenced Viral Genomes. ...
  https://www.wku.edu/biology/news/index.php?view=article&articleid=3220&return=archive
*  Zaire Ebola VP35 Protein
The viral genome encodes eight different proteins. More specifically, the viral protein (VP35) could play a major role in the ... IFNs are produced by the innate immune system as a response to viral infection. These interferons can interfere with viral ... to cleave viral RNA. VP35 acts as a type I IFN antagonist by binding to dsRNA that activates these endoribonucleases. Therefore ... The coiled coil domain is required for viral replication and nucleocapsid formation. The C-terminal IID contains a double- ...
  http://biology.kenyon.edu/BMB/jmol2014/KyeRhea/index.html
*  TCDB » SEARCH
GO:0019079 P:viral genome replication GO:0019082 P:viral protein processing ...
  http://www.tcdb.org/search/result.php?tc=1.A.53.1.4