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*  TFBSbank: a dedicated and comprehensive platform to dissect the big data of protein-DNA interaction in model species
Click here to view all the ChIP peaks in UCSC genome browser * *Please choose the target gene prediction method by clicking ... membrane fusion involved in viral entry into host cell. GO:0044800. 0.00548229173380715. multi-organism membrane fusion. ...
  http://tfbsbank.co.uk/result.php?jobdir=Results/DB1416/
*  Viruses Flashcards by krista rebar | Brainscape
3. Integation of the phage genome into the host genome. 4. Dormancy- viral genes not expressed by viral genome is transmitted ... viral genome is ssRNA which is anti-sense and therefore (doesnt code for a protein) complementary to the mRNA coding for viral ... is produced and degrades the host's genome.. Now the cell is destined to die. 4. Replication of the viral genome (many copies) ... viral genome is ssRNA which can also serve directly as mRNA. -uses the cells translation machinary to start making his own ...
  https://www.brainscape.com/flashcards/viruses-2445496/packs/4321944
*  Lecture 14 - Virus Overview Flashcards by Kyle Tuttle | Brainscape
4.Viral genome is exposed and replication of viral protein structures and genome occurs. 5.New viral particles begin to ... 3.Chronic, Non-Lytic (infected cells slowly release viral progeny without cell death). 4.Latent (virus genome become integrated ... Growth period: Constituents are assembled into many complete viral particles, the total number of which equal the yield ...
  https://www.brainscape.com/flashcards/lecture-14-virus-overview-2937479/packs/4774517
*  CVC2 - Capsid vertex component 2 - Human herpesvirus 8 type P (isolate GK18) (HHV-8) - CVC2 gene & protein
... assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the ... Capsid vertex-specific component that plays a role during viral DNA encapsidation, ... Host-virus interaction, Viral genome packaging, Viral penetration into host nucleus, Viral release from host cell, Virus entry ... assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the ...
  http://www.uniprot.org/uniprot/Q2HRB3
*  Plant Virology by Roger Hull by Roger Hull - Read Online
... such as the mechanisms by which viral genomes are expressed and replicated, and how the genomes interact with host genomes. ... including the ability to clone and manipulate plant viral genomes, be they RNA or DNA, the ability to express viral (and other ... in which many plant viral RNAs act as efficient messengers. Their use allowed the mapping of plant viral genomes by biochemical ... the control and recognition sequences in the genome that modulate expression of viral genes and genome replication; (vi) the ...
  https://www.scribd.com/book/282546320/Plant-Virology
*  AAV Vector Quality Control: Going the Extra Mile with NGS
But we are also going one step further with next-generation sequencing (NGS) of the viral genome. ... of the viral genome. Additionally, we check viral transgene expression in transduced cells whenever possible. This post will ... Viral Genome Sequencing. Thanks to our collaboration with seqWell, we can now use NGS to sequence all the DNA packaged inside ... As mentioned earlier, it is common to find DNA from the packaging cell genome, bacterial genomes, cloning vectors and helper ...
  http://blog.addgene.org/aav-vector-quality-control-going-the-extra-mile
*  OpenHelix: CMR
Viral Genomes at NCBI: Viral genome resources including single-stranded or double-stranded RNA or DNA viruses ... Genome Databases (prok + viral) : Genomic databases or repositories primarily aimed at prokaryotic or viral organisms. Some may ... VBRC: The Viral Bioinformatics Resource Center. UCSC Archaeal Genome Browser: Provides you with many research and analysis ... Containing over 400 genomes (and more than a gigabase of DNA sequence), CMR is a treasure-trove of microbial genome information ...
  http://www.openhelix.com/cgi/tutorialInfo.cgi?id=36
*  Biology News
Seven WKU students were part of a nationwide effort to investigate viral diversity by sequencing and analyzing the genomes of ... WKU Students Publish Analysis of Newly Sequenced Viral Genomes. ...
  https://www.wku.edu/biology/news/index.php?view=article&articleid=3220&return=archive
*  WKU News | Western Kentucky University
WKU Students Publish Analysis of Newly Sequenced Viral Genomes. 2018-03-13. WKU research shows set of anti-cancer compounds ...
  https://www.wku.edu/news/articles/index.php?view=archive&categoryid=14&multinewsid=12
*  Zaire Ebola VP35 Protein
The viral genome encodes eight different proteins. More specifically, the viral protein (VP35) could play a major role in the ... IFNs are produced by the innate immune system as a response to viral infection. These interferons can interfere with viral ... to cleave viral RNA. VP35 acts as a type I IFN antagonist by binding to dsRNA that activates these endoribonucleases. Therefore ... The coiled coil domain is required for viral replication and nucleocapsid formation. The C-terminal IID contains a double- ...
  http://biology.kenyon.edu/BMB/jmol2014/KyeRhea/index.html
*  Frontiers | CTL escape and viral fitness in HIV/SIV infection | Microbiology
Viruses with such CTL escape mutations often need additional viral genome mutations for recovery of viral fitness. Persistent ... Viruses with such CTL escape mutations often need additional viral genome mutations for recovery of viral fitness. Persistent ... Thus, multiple viral genome changes under CTL pressure are observed in the chronic phase of HIV/SIV infection. HIV/SIV ... Thus, multiple viral genome changes under CTL pressure are observed in the chronic phase of HIV/SIV infection. HIV/SIV ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2011.00267/full
*  A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1)...
... and this single residue variation dramatically increased the viral replication ability in MDCK cells and pathogenicity in BALB/ ... it is projected that mutations in specific regions of the viral genome, especially within the receptor binding domain of the ... Sequences analysis of the viral genomes. The full-length sequences of the viral genomes of wild type and egg-adaptive mutant A/ ... The mean viral RNA load (copy numbers per mg ± SD) (Figure 2C) and viral titers (TCID50 per mg ± SD) (Figure 2D) were ...
  https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-7-325
*  Ambisense | definition of ambisense by Medical dictionary
applied to single-stranded RNA viral genomes; part of the nucleotide sequence is of positive-sense, part is of negative-sense. ... The genome showed an ambisense organization and 2 major inversely arranged open reading frames encoding the Rep and Cap ... RHBV is a non-enveloped multipartite RNA virus, it has an 18 Kb-genome arranged in four negative sense and ambisense genomic ... Analysis of the genome sequence showed characteristics typical of circoviruses, including an ambisense organization with 2 ...
  http://medical-dictionary.thefreedictionary.com/ambisense
*  Transient coexpression of individual genes encoded by the triple gene block of potato mop-top virus reveals requirements for...
... may act in concert to facilitate cell-to-cell transport of viral RNA genomes. Transient expression of Potato mop-top virus ( ... Plant viral movement proteins: agents for cell-to-cell trafficking of viral genomes.. *William J. Lucas ... may act in concert to facilitate cell-to-cell transport of viral RNA genomes. Transient expression of Potato mop-top virus ( ... Microtubules in viral replication and transport.. *Annette Niehl, Eduardo José Peña, Khalid Amari, Manfred Heinlein ...
  https://www.semanticscholar.org/paper/Transient-coexpression-of-individual-genes-encoded-Zamyatnin-Solovyev/1437a50732f5df4420fdc7fcd70e069d67bb6f5d
*  TCDB » SEARCH
GO:0019079 P:viral genome replication GO:0019082 P:viral protein processing ...
  http://www.tcdb.org/search/result.php?tc=1.A.53.1.4
*  Researchers Show How Cells' DNA Repair Machinery Can Destroy Viruses - Redorbit
"It's like dropping a nuclear bomb on the viral genome," he says. ... leaving the viral DNA so riddled with holes that it was beyond ... its first order of business is to make a DNA copy of its own genome, then insert that copy into the host cell's genome. If ... The system's two vital components are high levels of a molecule that becomes embedded in viral DNA like a code written in ... so that each of the new cells gets its own copy of the genome. But because the T nucleotide, dTTP, is very similar to dUTP, a ...
  http://www.redorbit.com/news/health/1112768243/researchers-show-how-cells-dna-repair-machinery-can-destroy-viruses/
*  Characteristics of Cytomegalovirus | SpringerLink
The main criterion for including a virus in this enlarging group of viruses is viral morphology. The unique morphology of ... Within the hollow capsid was the core which contained the viral genome. The structure of the core was less well defined by ... The main criterion for including a virus in this enlarging group of viruses is viral morphology. The unique morphology of ...
  https://link.springer.com/chapter/10.1007/978-1-4684-4073-7_2
*  The T7 Group | SpringerLink
Wolstenholme, G. E. W., and O'Connor, M. (eds.), 1971, Strategy of the Viral Genome Ciba Foundation Symposium, Churchill ... Genetic Recombination Phage Genome Shigella Sonnei Template Specificity Amber Mutant These keywords were added by machine and ... Matthews, R. E. F., 1985, Viral taxonomy for the nonvirologist, Annu. Rev. Microbial. 39: 451.Google Scholar ... Hausmann, R., and Härle, E., 1971, Expression of the genomes of the related bacteriophages T3 and T7, in: Proceedings of the ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5424-6_8
*  UPENN Biomedical Graduate Studies | Carolina B. Lopez
López CB: Defective viral genomes: critical danger signals of viral infections (Gem-Review). J Virol 88: 8720-3, August 2014.. ... Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, and López CB: Defective Viral Genomes Arising In Vivo Provide ... Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus ... Highly Immunostimulatory RNA Derived from a Sendai Virus Defective Viral Genome. Vaccine 31(48): 5713-21, November 2013.. ...
  http://www.med.upenn.edu/apps/faculty/index.php/g20000320/p8399502
*  Bluetongue virus uses unique viral enzymes to replicate - Thaindian News
... uses unique viral enzymes to replicate, which is key to the establishment of infection. ... viral enzymes, viral genome, viral mutations, viruses ... "Replication of the viral genome is the "heart" of a virus. It ... Bluetongue virus uses unique viral enzymes to replicate. July 9th, 2008 - 3:20 pm ICT by ANI Tweet. ... Bluetongue virus uses unique viral enzymes to replicate. At the Roy laboratory we have been using bluetongue as a model system ...
  http://www.thaindian.com/newsportal/entertainment/bluetongue-virus-uses-unique-viral-enzymes-to-replicate_10069483.html
*  Cardiac Fibroblasts Aggravate Viral Myocarditis: Cell Specific Coxsackievirus B3 Replication
... during the chronic phase of viral myocarditis virus replication has ceased but viral genome persists in the myocardium. ... Copy Numbers of Viral Genome and Intermediate Strand for Virus Replication. Since it is not clear if macrophages are really ... Figure 4: CVB3 copy numbers of the viral RNA genome (+) strand as well as the intermediate (−) RNA strand for virus replication ... The copy number of the viral RNA genome (+) strand and the copy number of the intermediate (−) strand needed for virus ...
  https://www.hindawi.com/journals/mi/2014/519528/
*  Antigenic drift - Wikipedia
However, viral genomes are constantly mutating, producing new forms of these antigens. If one of these new forms of an antigen ... 3 substitutions per site per year during viral genome replication.[7] Mutations in the surface proteins allow the virus to ...
  https://en.wikipedia.org/wiki/Antigenic_drift
*  Lentivirus - Wikipedia
Genome organization and replication[edit]. As with all retroviruses, lentiviruses have gag, pol and env genes, coding for viral ... The enzyme uses the viral RNA genome as a template for the synthesis of a complementary DNA copy. Reverse transcriptase also ... Integrase processes the LTR before inserting the viral genome into the host DNA. Tat acts as a trans-activator during ... integrating their genome into the host germline genome, so that the virus is henceforth inherited by the host's descendants. ...
  https://en.wikipedia.org/wiki/Lentivirus
*  AduPARE1A and gemcitabine combined treatment trigger synergistic antitumor effects in pancreatic cancer through NF-κB mediated...
Mechanistic studies showed that the synergistic cell death was not due to an increase in viral replication but occurred through ... apoptosis and viral production. We also investigated the effects of the combination on tumor growth and mice survival in two ... Viral genomes quantification. BxPC-3 and PANC-1 cells were infected with 4000 vp/cell and 200 vp/cell, respectively. Culture ... Viral genomes were determined by Real Time PCR using SYBR Green I Master mix (Roche Diagnostics, Switzerland) and Hexon primers ...
  https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-015-0413-2