*  The RCAS System Viral Replication and Behavior
After viral and cellular membranes fuse, the viral core is in the host cytoplasm, where the single-stranded RNA genome of the ... Once the viral DNA has access to the host genome, integration can take place. Integration links the ends of the linear viral ... The LTRs of the provirus are shown as a series of three boxes (U3, R, and U5). The viral genome is divided into gag, pol, env, ... Because the viral DNA becomes part of the host genome, infection is permanent. The infected cells, and all their progeny, will ...
  https://home.ncifcrf.gov/hivdrp/RCAS/replication.html
*  Frontiers | Kaposi's Sarcoma Herpesvirus Genome Persistence | Microbiology
In order to persist in proliferating tumor cells, the viral genome replicates once per cell cycle and then segregates to ... LANA serves as a molecular tether, bridging the viral genome to mitotic chromosomes to ensure that KSHV DNA reaches progeny ... In order to persist in proliferating tumor cells, the viral genome replicates once per cell cycle and then segregates to ... LANA serves as a molecular tether, bridging the viral genome to mitotic chromosomes to ensure that KSHV DNA reaches progeny ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.01149/full
*  Complete Genome Sequence of Bovine Viral Diarrhea Virus-1 Strain Egy/Ismailia/2014, Subtype 1b - Semantic Scholar
The virus genome is composed of 12,217 nucleotides organized as one open reading frame encoding 3,898 amino acids. This report ... we report the complete genome sequence of bovine viral diarrhea virus-1b (BVDV-1b), strain Egy/Ismailia/2014. ... we report the complete genome sequence of bovine viral diarrhea virus-1b (BVDV-1b), strain Egy/Ismailia/2014. The virus genome ... Complete Genome Sequence of a Bovine Viral Diarrhea Virus Subgenotype 1g Strain Isolated in Italy. *Moira Bazzucchi. , Luigi ...
  https://www.semanticscholar.org/paper/Complete-Genome-Sequence-of-Bovine-Viral-Diarrhea-Soltan-Wilkes/dbe7d8693d19eb5853305d0f2fa156eb2e76dca6
*  Pathogenicity of a Very Virulent Strain of Marek's Disease Herpesvirus Cloned as Infectious Bacterial Artificial Chromosomes
Since herpesviruses have large genomes, between 120 kbp-230 kbp in size, the manipulation of the viral genomes to identify the ... the genome sequence of these viral pathotypes has indicated changes in parts of their genomes [20, 21]. Although the analysis ... Our study shows that individual viral genomes, despite originating from a single population of parental virus, can differ in ... Detection of Viral Antigen in the Brain of C12/130 Virus-Infected Birds. Previously, we have reported the detection of viral ...
  https://www.hindawi.com/journals/bmri/2011/412829/
*  Mapping of HPV11 promoter activity from E6/E7-containin | Open-i
The transcription map of HPV11 in U2OS cells adequately reflects the initial and stable replication phases of the viral genome. ... The transcription map of HPV11 in U2OS cells adequately reflects the initial and stable replication phases of the viral genome ... E2 protein is used to control viral gene expression and copy number of the HPV11 genome. The analysis of HPV11 E1 expression ... E2 protein is used to control viral gene expression and copy number of the HPV11 genome. The analysis of HPV11 E1 expression ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4414447_12985_2015_292_Fig7_HTML&req=4
*  An overview of gene expression profiles in IAPV infecte | Open-i
Genome, Viral. *Host-Pathogen Interactions. *In Situ Hybridization. *Oligonucleotide Array Sequence Analysis ... suggesting that viral infection causes significant disturbance in energy-related host processes. The expression of genes ... suggesting that viral infection causes significant disturbance in energy-related host processes. The expression of genes ... a novel therapeutic strategy for limiting multiple honey bee viruses simultaneously and reducing colony losses due to viral ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4117608_ppat.1004261.g005&req=4
*  Bootscan analysis of genotypes I, A, B, C, and G compar | Open-i
For the analysis of the first 400 nt, the beginning of the genome was duplicated at the end of the sequence: nt 3200-4000 ... For the analysis of the first 400 nt, the beginning of the genome was duplicated at the end of the sequence: nt 3200-4000 ... amplified by complete genome PCR, showed similarities with genotype C (nt 1400-3000), A (nt 3000-400), and G (nt 400-1400) by ... amplified by complete genome PCR, showed similarities with genotype C (nt 1400-3000), A (nt 3000-400), and G (nt 400-1400) by ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2630741_08-0437-F2&req=4
*  TSRI - News & Views
That clearly showed that the viral genome was integrated. And here you have a viral genome that becomes part of the cellular ... postulated that the viral genome becomes integrated into the cellular genome, and that this was the transforming event. ... that you could actually take part of the viral-genome off, you could delete it, and still retain a virus that was perfectly ... Varmus-I participated in that as well-who showed that that particular piece of viral genome deleted in these non-transforming ...
  http://www.scripps.edu/newsandviews/e_20050404/vogt.html
*  Adoptive Immunotherapy for EBV-Associated Malignancies | SpringerLink
Detection of epstein-barr viral genomes in reed-sternberg cells of hodgkin's disease. New England Journal of Medicine 1989; 320 ... Epstein-barr viral DNA in tissues of hodgkin's disease. American Journal of Pathology 1987; 129(1): 86-91.PubMedGoogle Scholar ... High incidence of epstein-barr virus genomes in hodgkin's disease. American Journal of Pathology 1990; 137(1): 13-18.PubMed ... CD4+ T cells are required to sustain CD8+ cytotoxic T cell responses during chronic viral infection. Journal of Virology 1994; ...
  https://link.springer.com/chapter/10.1007/978-1-4615-4987-1_10
*  rhinovirus
The result gave us the first glimpse of the viral genome. I then found that a DNA copy of poliovirus RNA is infectious in ... The moratorium on recombinant DNA research had just been lifted, and it was now possible to clone complete viral DNA genomes. ... I moved back to New York City in September 1982 with a DNA copy of the poliovirus genome in hand. In the last few weeks in the ... We found that the type 2 Lansing viral capsid was important for the ability to infect mice. Later, we narrowed this down to 8 ...
  http://www.virology.ws/tag/rhinovirus/
*  Plus it
The total length of the recombinant viral genome is 37,953 bp. Its structure is illustrated in Fig. 1 . The package and ... which could interfere with viral replication and diminish viral production efficiency (27). We did an in vitro viral ... Viral replication assay. C4-2, CWR22rv, PC-3, DU-145, fibroblast, and hNHeps cells were seeded in six-well plates (1 × 106 per ... Tissue-specific viral replication and FasL expression were analyzed, and the tumor killing effect of AdIU3 was investigated ...
  http://clincancerres.aacrjournals.org/content/13/18/5463
*  Free Medical Flashcards about Virology Review 4
... a new chimeric or hybrid genome is formed via intramoleculr exchange of viral genomes. occurs when viral RdRp complex switches ... occurs when very similar segmented viral genomes coinfect the same cell. Example: Influenza A. ... VIRAL INFECTIONS THAT MAY BE/HAVE BEEN CONTROLLED. Must have human or readily controllable reservoir; Must be able to induce an ... Examples of Emerging Viral Disease. HIV?AIDS, Hantavirus pulmonary syndrome (HPS), West Nile encephalitis (WNV), Severe Acute ...
  https://www.studystack.com/flashcard-243487
*  chap18studyguide - Chapter 18 The Genetics of Viruses and Bacteria Study Guide Overview Microbial Model Systems Viruses and...
A virus is called a DNA virus or an RNA virus, according to the kind of nucleic acid that makes up its genome. ° The viral ... The capsid is the protein shell enclosing the viral genome. • Capsids are built of a large number of protein subunits called ... These viral envelopes are derived from the membrane of the host cell. ° They also have some host cell viral proteins and ... Concept 18.1 A virus has a genome but can reproduce only within a host cell A virus is a genome enclosed in a protective coat. ...
  https://www.coursehero.com/file/84468/chap18studyguide/
*  Epstein-Barr virus in gastric adenocarcinomas: association with ethnicity and CDKN2A promoter methylation | Journal of Clinical...
Expression of the viral genome in an undifferentiated gastric carcinoma. Diagn Mol Pathol1992;1:103-8. ... Because of the spontaneous deamination of methylated cytosines, CpGs tend to be reduced in the viral genome. ... and the BamHI-A regions of the viral genome, but no transcripts of LMP1, LMP2B, or EBNA2. Similarly, zur Hausen et al have ... Monoclonality in the size of the fused termini of the viral genome indicates that the virus was present in the original cell ...
  http://jcp.bmj.com/content/55/9/669
*  Project : USDA ARS
This will continue until the viral population is completely avirulent. Preceeding populations will have their viral genome ... Following analysis, key genetic changes will be introduced into the virulent viral genome to address whether the polymorphisms ... Our virulent BAC cloned MDV genome that generates a fully virulent virus will be passed in cell culture, which is known to ... Depending on the replicate, 41 to 95 SNPs were identified that were present in at least 2% of the viral population. Genes with ...
  https://www.ars.usda.gov/research/project/?accnNo=418579&fy=2012
*  retrovirus facts, information, pictures | Encyclopedia.com articles about retrovirus
... which replicate their genome through a double-stranded viral deoxyribonucleic acid (DNA) intermediate in the nucleus of the ... This DNA copy of the retrovirus genome is referred to as the provirus or proviral DNA. The genomes of most vertebrates contain ... This process is catalyzed by another viral enzyme called integrase (IN). Since there is no matching sequence between the viral ... Concomitantly, viral glycoproteins are translated as polyproteins from a smaller-sized, spliced viral mRNA on membrane-bound ...
  https://www.encyclopedia.com/plants-and-animals/microbes-algae-and-fungi/moneran-and-protistan/retrovirus
*  Picornavirus - Wikipedia
Its genome is linear, single stranded positive sense RNA with a viral genome-linked protein (VPg) covalently linked at the 5' ... Depending on the type and degree of dehydration the viral particle is around 27-30 nm in diameter. The viral genome is around ... Their genome single-stranded (+) sense RNA is that functions as mRNA after entry into the cell and all viral mRNA synthesized ... Picornaviruses have a viral protein (VPg) covalently linked to 5' end of their genomes instead of 7-methylguanosine cap like ...
  https://en.wikipedia.org/wiki/Picornavirus
*  Virology - Wikipedia
They contained the foreign gene but did not contain the viral genome and therefore could not reproduce. Tests in mice were ... An endogenous retrovirus (ERV) is a retrovirus whose genome has been permanently incorporated into the germ-line genome of some ... some viral infection might even be beneficial to the host.[7] The lethal viral diseases are believed to have resulted from an " ... then integrated into the host's genome and expressed from that template. The viral enzyme reverse transcriptase, which along ...
  https://en.wikipedia.org/wiki/Virology
*  gag-pol - Gag-Pol polyprotein - Human immunodeficiency virus type 2 subtype A (isolate ST) (HIV-2) - gag-pol gene & protein
... recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi ... Viral genome integration, Viral penetration into host nucleus, Virion maturation, Virus entry into host cell, Virus exit from ... Strand displacement synthesis by RT to the PBS and PPT ends produces a blunt ended, linear dsDNA copy of the viral genome that ... br>,/br>These range from a single component such as Viral genomes to several components as in the case of eukaryotic ...
  http://www.uniprot.org/uniprot/P20876
*  gag-pol - Gag-Pol polyprotein - Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1) - gag-pol gene &...
Viral genome integration, Viral penetration into host nucleus, Viral release from host cell, Virion maturation, Virus entry ... Strand displacement synthesis by RT to the PBS and PPT ends produces a blunt ended, linear dsDNA copy of the viral genome that ... This step requires a complex comprising the viral genome, matrix protein, Vpr and integrase. This complex is called the pre- ... Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that converts the viral RNA genome into dsDNA in the ...
  http://www.uniprot.org/uniprot/P18802
*  CiNii 論文 - Advances in Genomic Research on Hepatitis C Virus with a Useful Tool, Replicon...
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome CHOO Q. -L. ... Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication MIYANARI ... Production of infectious hepatitis C virus in tissue culture from a cloned viral genome WAKITA T. ... Rapid decline of viral RNA in hepatitis C patients treated with VX-950 : a phase Ib, placebo-controlled, randomized study ...
  http://ci.nii.ac.jp/naid/10021988439
*  Resource centre | Oxford Nanopore Technologies
... which is more than sufficient to span entire viral genomes in single reads. In contrast, to obtain a complete genome sequence ... By viral standards, Pithovirus is enormous, 1.5 mm long, and has a large AT-rich genome, approximately 600 kb in length. We ... Genome sequencing in viral outbreaks is desirable to characterise the infectious agent and determine its evolutionary rate. ... Whole genome sequencing of influenza virus genomes using MinION A presentation by Nicole Moore at London Calling 2015. ...
  https://nanoporetech.com/index.php/taxonomy/term/230
*  Mastadenovirus - Wikipedia
The genome codes for 40 proteins. Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral ... Import of the viral genome into host nucleus mediated by core protein VII. Transcription of early genes (E genes) by host RNA ... Microtubular transport toward nucleus of the viral genome still protected by the core protein VII and a partial capsid mainly ... "Viral Zone". ExPASy. Retrieved 1 July 2015. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 1 July 2015. taxonomy. "Taxonomy ...
  https://en.wikipedia.org/wiki/Mastadenovirus
*  Genome polyprotein - Coxsackievirus A24 (strain EH24/70)
... they shape a pore in the host membrane through which viral genome is translocated to host cell cytoplasm. After genome has been ... composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly ... Pore-mediated penetration of viral genome into host cell, Transport, Viral attachment to host cell, Viral immunoevasion, Viral ... Viral protein genome-linked: acts as a primer for viral RNA replication and remains covalently bound to viral genomic RNA. VPg ...
  http://www.uniprot.org/uniprot/P36290
*  Science + Technology | UCLA
Studies reveal key insights about how viral RNA genomes organize and replicate. November 03, 2015 UCLA research reveals the ...
  http://newsroom.ucla.edu/topics/