*  T5likevirus - Wikipedia
The complete genomes, as well as two other similar, unclassified genomes are available here. The virus attaches to the host ... and degrades the cell wall using viral exolysin enough to eject the viral DNA into the host cytoplasm via long flexible tail ... Once the viral genes have been replicated, the procapsid is assembled and packed. The tail is then assembled and the mature ... Genomes are linear, around 121kb in length. The type species, Enterobacteria phage T5, and several other species have been ...
  https://en.wikipedia.org/wiki/T5likevirus
*  The RCAS System Viral Replication and Behavior
After viral and cellular membranes fuse, the viral core is in the host cytoplasm, where the single-stranded RNA genome of the ... Once the viral DNA has access to the host genome, integration can take place. Integration links the ends of the linear viral ... The LTRs of the provirus are shown as a series of three boxes (U3, R, and U5). The viral genome is divided into gag, pol, env, ... Because the viral DNA becomes part of the host genome, infection is permanent. The infected cells, and all their progeny, will ...
  https://home.ncifcrf.gov/hivdrp/RCAS/replication.html
*  Frontiers | Kaposi's Sarcoma Herpesvirus Genome Persistence | Microbiology
In order to persist in proliferating tumor cells, the viral genome replicates once per cell cycle and then segregates to ... LANA serves as a molecular tether, bridging the viral genome to mitotic chromosomes to ensure that KSHV DNA reaches progeny ... In order to persist in proliferating tumor cells, the viral genome replicates once per cell cycle and then segregates to ... LANA serves as a molecular tether, bridging the viral genome to mitotic chromosomes to ensure that KSHV DNA reaches progeny ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.01149/full
*  Complete Genome Sequence of Bovine Viral Diarrhea Virus-1 Strain Egy/Ismailia/2014, Subtype 1b - Semantic Scholar
The virus genome is composed of 12,217 nucleotides organized as one open reading frame encoding 3,898 amino acids. This report ... we report the complete genome sequence of bovine viral diarrhea virus-1b (BVDV-1b), strain Egy/Ismailia/2014. ... we report the complete genome sequence of bovine viral diarrhea virus-1b (BVDV-1b), strain Egy/Ismailia/2014. The virus genome ... Complete Genome Sequence of a Bovine Viral Diarrhea Virus Subgenotype 1g Strain Isolated in Italy. *Moira Bazzucchi. , Luigi ...
  https://www.semanticscholar.org/paper/Complete-Genome-Sequence-of-Bovine-Viral-Diarrhea-Soltan-Wilkes/dbe7d8693d19eb5853305d0f2fa156eb2e76dca6
*  Endogenous viral element - Wikipedia
EVEs may be entire viral genomes (proviruses), or fragments of viral genomes. They arise when a viral DNA sequence becomes ... An endogenous viral element (EVE) is a DNA sequence derived from a virus, and present within the germline of a non-viral ... "Endogenous Viral Elements in Animal Genomes". PLoS Genetics. 6 (11): e1001191. doi:10.1371/journal.pgen.1001191. PMC 2987831 . ... bornaviruses and circoviruses have been identified in vertebrate genomes. In plant genomes, EVEs derived from pararetroviruses ...
  https://en.wikipedia.org/wiki/Endogenous_viral_element
*  Pathogenicity of a Very Virulent Strain of Marek's Disease Herpesvirus Cloned as Infectious Bacterial Artificial Chromosomes
Since herpesviruses have large genomes, between 120 kbp-230 kbp in size, the manipulation of the viral genomes to identify the ... the genome sequence of these viral pathotypes has indicated changes in parts of their genomes [20, 21]. Although the analysis ... Our study shows that individual viral genomes, despite originating from a single population of parental virus, can differ in ... Detection of Viral Antigen in the Brain of C12/130 Virus-Infected Birds. Previously, we have reported the detection of viral ...
  https://www.hindawi.com/journals/bmri/2011/412829/
*  Statistical Analyses of Next Generation Sequence Data: A Partial Overview
Single-Molecule DNA Sequencing of a Viral Genome. Science. 2008;320:106-109. [PubMed] ... Ultrafast and memory efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009;10:R25. [PMC free ... Kircher M, Stenzel U, Kelso J. Improved base calling for the Illumina Genome Analyzer using machine learning strategies. Genome ... Genome Res. 2008;18:1851-1858. [PubMed]. 38. Mardis ER. Next generation DNA sequencing methods. Annu Rev Genomics Hum Genet. ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2989618/
*  Interleukin 27 and viral hepatitis: Smarter than the average cytokine - Laurence - 2009 - Hepatology - Wiley Online Library
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 2005; 11: 791-796.. *CrossRef ... Interleukin 27 and viral hepatitis: Smarter than the average cytokine†‡. Authors. *. Arian Laurence,. Corresponding author*E- ... Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med 2001; 194: 1395-1406.. * ... A few caveats remain: IL-27 has been shown to induce IL-10 expression,14 a cytokine linked to both elevated viral titers and an ...
  http://onlinelibrary.wiley.com/doi/10.1002/hep.23063/full
*  Life | Free Full-Text | Horizontal Gene Transfer among Bacteria and Its Role in Biological Evolution | HTML
The viral genome becomes thereby insensitive to restriction by site-specific methylation (modification). This is a kind of ... of the propagating progeny viral particles contain a segment from the host chromosome rather than a reproduced viral genome. ... Genome Biol. Evol. 2011, 3, 1090-1092. [Google Scholar] [CrossRef]. *Arber, W. Genetic engineering compared to natural genetic ... In the late 1950's I had the chance to identify for the first time such a hybrid genome in λgal derivatives of phage λ. This ...
  http://www.mdpi.com/2075-1729/4/2/217/htm
*  Interferon question, alpha 2A/2B - Hepatitis C - MedHelp
... neither ifn nor riba target any specific part of the viral genome. While vx950 blocks ns3 and r1626 blocks ns5b the soc drugs ... neither ifn nor riba target any specific part of the viral genome. While vx950 blocks ns3 and r1626 blocks ns5b the soc drugs ... J Viral Hepat. 2007 Oct;14(10):721-9 Di Bisceglie AM, Ghalib RH, Hamzeh FM, Rustgi VK. Division of Gastroenterology and ... J Viral Hepat. 2007 Oct;14(10):721-9 Di Bisceglie AM, Ghalib RH, Hamzeh FM, Rustgi VK. Division of Gastroenterology and ...
  http://www.medhelp.org/posts/Hepatitis-C/Interferon-question--alpha-2A-2B/show/410149
*  News Release | Scripps Research
... an essential step in the formation of infectious viral particles; the nucleocapsid is the viral genome protected by a protein ... JUPITER, FL, March 9, 2009-A team from The Scripps Research Institute has found a way to inhibit viral production of the ... Core, the most conserved protein among all HCV genotypes, plays several essential roles in the viral cycle in the host cell; ... When added to HCV-infected cells, each of the three peptides blocked release but not replication of infectious virus; viral RNA ...
  https://www.scripps.edu/news-and-events/press-room/2009/030909.html
*  Plasmaviridae - Wikipedia
After initial infection of the viral genome the virus may become latent within the host. Lysogeny involves integration into the ... The genome has a rather high G-C content of ~32%. The genome has 14 open reading frames, and encodes at least 15 proteins, of ... Viral replication is cytoplasmic. DNA-templated transcription is the method of transcription. The virus exits the host cell by ... "Viral Zone". ExPASy. Retrieved 15 June 2015. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015. Büchen-Osmond, C. ( ...
  https://en.wikipedia.org/wiki/Plasmaviridae
*  Virus - Wikipedia
... the viral genome is also replicated. The viral genome is mostly silent within the host. However, at some point, the provirus or ... viral protein synthesis, possible assembly of viral proteins, then viral genome replication mediated by early or regulatory ... The smallest viral genomes - the ssDNA circoviruses, family Circoviridae - code for only two proteins and have a genome size of ... This membrane is studded with proteins coded for by the viral genome and host genome; the lipid membrane itself and any ...
  https://en.wikipedia.org/wiki/Virus_structure
*  Q about recombination
From: kuiken at amc.uva.nl , Subject: Q about recombination , Does anyone know of a paper describing genes from a viral genome ... genome, due to recombination? I've been told that this has been , described by Temin, but I cannot find the paper. Any other ... It is not necessarily so that genes will be more independent the further they are apart on the genome - many of the simple RNA ... have what looks like almost an entire picornavirus-like genome with bits tacked on to either end (CP at 3', movement factors at ...
  http://www.bio.net/bionet/mm/virology/1995-November/004868.html
*  Researchers show how cells' DNA repair machinery can destr... ( A team of researchers based at Johns...)
"It's like dropping a nuclear bomb on the viral genome," he says. ... Researchers develop tool to evaluate genome sequencing method. ... its first order of business is to make a DNA copy of its own genome, then insert that copy into the host cell's genome. If ... But in cells with both high dUTP and vigilant hUNG2, the repair process turned into a hack job, Stivers says, leaving the viral ... The system's two vital components are high levels of a molecule that becomes embedded in viral DNA like a code written in ...
  http://www.bio-medicine.org/biology-news-1/Researchers-show-how-cells-DNA-repair-machinery-can-destroy-viruses-28404-1/
*  Articles Added on January 4, 2013
Analysis of the viral genome identified 14 potential UL34 binding sites. Using mobility shift experiments, UL34 bound to all ... associated with some viral infections. However, technological capabilities for identifying viral glycoproteins and their ... Like all other organisms, archaeal cells are susceptible to viral infections, and to date, about 100 archaeal viruses have been ... The human cytomegalovirus UL34 gene encodes a sequence-specific DNA binding protein that downregulates expression of the viral ...
  http://www.biomedsearch.com/added/20130104-p13.html
*  Crystal structure of poxvirus DNA polymerase
This protein is essential for the replication of the viral genome. The structure allows an understanding of anti-viral ...
  http://www.esrf.eu/home/news/spotlight/content-news/spotlight/spotlight308.html
*  Gene Identification in Prokaryotic Genomes, Phages, Metagenomes, and EST Sequences with GeneMarkS Suite - Current Protocols
... in genomes of viruses and phages, and in prokaryotic metagenomic sequences, as well as in EST sequences with spliced‐out ... Improving gene annotation in complete viral genomes. Nucleic Acids Res. 31:7041‐7055. ... How to interpret anonymous genome? Machine learning approach to gene identification. Genome Res. 8:1154‐1171. ... Detection of new genes in the bacterial genome using Markov models for three gene classes. Nucleic Acids Res. 23:3554‐3562. ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-bi0405.html?quicktabs_cp=toc
*  Plus it
Viral genome content was measured by quantitative real-time PCR. *, P , 0.05. B, a to c, in vitro cytocidal effect of AV22EL ... AV22EL genome lacks the adenoviral E3 region and contains the I-A33Pr-E1A cassette introduced in the E1 region of the viral ... Assessment of intratumor viral replication. LoVo cells (5 × 106) were injected s.c. and allowed to form tumors in the flank of ... As an alternative way to establish the selectivity of AV22EL, cells were infected with AV22EL or Ad-WT and the viral yield was ...
  http://clincancerres.aacrjournals.org/content/15/9/3037
*  Expression of TBC1D20 in cancer - Summary - The Human Protein Atlas
GO:0044829 [positive regulation by host of viral genome replication]. GO:0046726 [positive regulation by virus of viral protein ... GO:0016032 [viral process]. GO:0017137 [Rab GTPase binding]. GO:0019068 [virion assembly]. GO:0030173 [integral component of ... generated by the The Cancer Genome Atlas (TCGA). RNA cancer tissue category is calculated based on mRNA expression levels ... RNA category is calculated separately for The Cancer Genome Atlas (TCGA) data from cancer tissues and internally generated ...
  http://www.proteinatlas.org/ENSG00000125875-TBC1D20/pathology
*  difference in band sizes !: post #1
What is your positive control? A tissue isolate, purified virus or what? What part of viral genome do you use for PCR? ... What is your positive control? A tissue isolate, purified virus or what? What part of viral genome do you use for PCR?. ...
  http://www.protocol-online.org/forums/topic/21191-difference-in-band-sizes/
*  Plus it
At 48 hours posttreatment, the viral load was 1,258 genomes per cell in HA treated with SAHA and it dropped to 172 genomes per ... EBV viral load was presented as number of viral genomes per cell. Data were determined by triplicate wells in a 96-well plate ... Data are presented as number of viral genomes per cell. Error bars show SEs of triplicate wells. E, HONE1-EBV cells were ... Because bortezomib and SAHA have synergistic action on various malignant cell types and both drugs can induce viral lytic cycle ...
  http://mct.aacrjournals.org/content/12/5/747
*  Liggett Lab | USF Health
... analysis of the relationships between viral genomes and asthma phenotypes. *Genomic-based drug discovery, most recently ... Determination of the full genome sequences of human Rhinoviruses using high throughput next-generation sequencing technologies ... the largest in the human genome) carry out signaling how they participate in heart failure and asthma, and how a patient or ...
  http://health.usf.edu/research/liggett_lab/
*  Argininosuccinate synthetase 1 depletion produces a metabolic state conducive to herpes simplex virus 1 infection. - PubMed -...
Primers against the viral gene UL30 were used as a proxy for viral genomes. (B, Upper) Extracellular vDNA accumulation over the ... Knockdown of AS1 robustly enhanced viral genome replication and the production of infectious virus. Using high-resolution ... AS1 knockdown increases the protein and transcript levels of viral genes. (A) Western blot showing levels of viral proteins ... AS1 knockdown increases extracellular viral DNA and improves infectivity. (A) Intracellular viral DNA (vDNA) accumulation over ...
  https://www.ncbi.nlm.nih.gov/pubmed/24297925
*  Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia | PNAS
A) Scatter plot showing the mean viral genome copy number per 105 TG cells. (B) Comparison of the viral copy numbers between ... A prominent viral factor could be LAT, shown to control latent viral infection by protecting neurons from undergoing apoptosis ... CD4 T-Cell Memory Responses to Viral Infections of Humans Show Pronounced Immunodominance Independent of Duration or Viral ... This finding supports the long-held conclusion that the immune system controls viral replication and suppresses viral ...
  http://www.pnas.org/content/104/9/3496