*  Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology | G3: Genes | Genomes...
Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology. Qisheng Zuo, Yinjie ... Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology. Qisheng Zuo, Yinjie ... Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology. Qisheng Zuo, Yinjie ... 2014 Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343(6166): 84-87. ...
  http://www.g3journal.org/content/6/6/1787
*  Conditional Knockout Mouse | Genome Engineering | genOway
Use conditional Knockout mice with tissue-specific or temporal gene inactivation to bypass embryonic lethality, compensatory ... Inducible Knockout mouse model. This strategy can bypass the limits that are usually observed with constitutive Knockout mouse ... Learn more about tissue-specific Knockout mouse models Learn more about inducible Knockout mouse models ... A conditional Knockout mouse defines an animal model in which a gene of interest can be:. * Inactivated in specific cell types ...
  https://www.genoway.com/services/customized-mouse/knockout-models/conditional-ko.htm
*  Inducible Knockout Mouse | Genome Engineering | genOway
Use an inducible Knockout mouse to inactivate your gene in an age-specific manner, and enable studies at defined development ... Inducible Knockout Mouse Model An inducible Knockout mouse defines a conditional biological model in which the target gene of ... This strategy can bypass the limits that are usually observed with conventional Knockout (constitutive KO) models (e.g. ... Custom Knockout Mouse Services at genOway. genOway provides a one-stop solution for the design, creation and analysis of your ...
  https://www.genoway.com/services/customized-mouse/knockout-models/conditional-ko-time.htm
*  Protein Function Knockout Mouse | Genome Engineering | genOway
A protein function Knockout mouse defines an model in which one or more nucleotides are mutated in a way that the protein ... Protein Function Knockout Mice (Point Mutations, Dead Kinase, etc.). Get supplemental information, a quote, and estimated ... Strengths and limitations of protein function Knockout mouse models. +. * Best way to reproduce human disease when due to ... A protein function Knockout mouse defines an animal model in which one or more nucleotides are mutated in a way that the ...
  https://www.genoway.com/services/customized-mouse/knockout-models/functional-ko.htm
*  Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells | Science
Improving Whole-Genome Screens. Improved methods are needed for the knockout of individual genes in genome-scale functional ... Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells. By Ophir Shalem, Neville E. Sanjana, Ella Hartenian, Xi Shi, David ... Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells. By Ophir Shalem, Neville E. Sanjana, Ella Hartenian, Xi Shi, David ... Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells Message Subject. (Your Name) has forwarded a page to you from ...
  http://science.sciencemag.org/content/343/6166/84?ijkey=dbeca59cfb5137e14cec0d350feb9be3c8456459&keytype2=tf_ipsecsha
*  Constitutive Knockout Rat Model | Genome Engineering | genOway
A constitutive Knockout rat defines a model in which the target gene is permanently inactivated in the whole animal, in every ... A constitutive Knockout rat, also referred to as conventional or whole-body Knockout (KO), defines a rat model in which the ... Constitutive Knockout Rat Models (Conventional). Get supplemental information, a quote, and estimated timeframe for generating ... Typical applications for constitutive Knockout rat models. For academic research: * Determine main functions of the gene and/or ...
  https://www.genoway.com/services/customized-rat/constitutive-knockout.htm
*  Knockout Mouse Project - National Human Genome Research Institute (NHGRI)
Nature News: Mouse Library Set to be Knockout. June 15, 2011. *Nature Article: A conditional knockout resource for the genome- ... List of Available Knockout Mice [nih.gov]. All knockout lines that have been obtained, with links to how to obtain the mice and ... Knockout Mouse Phenotyping (KOMP2). The NIH Common Fund. Trans-NIH Mouse Initiatives. The NIH Web site for the Knockout Mouse ... Knockout Mouse Phenotyping (KOMP2). The NIH Common Fund. Trans-NIH Mouse Initiatives. The NIH Web site for the Knockout Mouse ...
  https://www.genome.gov/17515708/
*  2009 News Feature: Making a Mightier Knockout Mouse - National Human Genome Research Institute (NHGRI)
To learn more about the international Knockout Mouse Project, go to The Knockout Mouse Project. To learn more about knockout ... Making a Mightier Knockout Mouse. A regular C57BL/6 mouse with black fur (top) sits next to a C57BL/6 knockout mouse (bottom) ... A Better Knockout Mouse. Still, the quest to create black 6 knockout mice continued because the 129 mouse strain displays ... To request any of the ES cell lines produced by the Knock Out Mouse Project, go to The Knock Out Mouse Project Repository, or ...
  https://www.genome.gov/27532436/making-a-mightier-knockout-mouse/
*  The mammalian gene function resource: the international knockout mouse consortium, Mammalian Genome | 10.1007/s00335-012-9422-2...
Mammalian Genome" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications ... A conditional knockout resource for genome-wide analysis of mouse gene function ... The knockout mouse project. Austin, CP; Battey, JF; Bradley, A; Bucan, M; Capecchi, M; Collins, FS; Dove, WF; Duyk, G; Dymecki ... The European dimension for the mouse genome mutagenesis program. Auwerx, J; Avner, P; Baldock, R; Ballabio, A; Balling, R; ...
  https://www.deepdyve.com/lp/springer-journals/the-mammalian-gene-function-resource-the-international-knockout-mouse-Ft86oUKCGG
*  Gadd45a knockout mice resemble p53 knockouts | Genome Biology | Full Text
The tumor suppressor gene p53 has been referred to as the 'guardian of the genome'. Mutations in the p53 gene are found in many ... The knockout mice also displayed increased numbers of cells in the thymus without evidence of decreased apoptosis. Finally, the ... Mice with a disrupted Gadd45a gene share several phenotypic characteristics with p53 knockout mice, including genomic ... supporting the notion that Gadd45a has a broad role in surveillance of genome stability. They refer to Gadd45a as an 'alarm ...
  https://0-genomebiology-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/gb-2000-1-1-reports002
*  TSG knock out in hiPSCs - EGA European Genome-Phenome Archive
The European Genome-phenome Archive (EGA) is part of the ELIXIR infrastructure.. EGA is an Elixir Core Data Resource. Learn ...
  https://ega-archive.org/studies/EGAS00001002262
*  Cell Based Assays / In vitro > Genetic Screens Laboratory Product Directory and Equipment Reviews on...
CRISPR Human Genome 80K Knockout Library (plasmid). Cellecta. Cellecta's 80K Single-module Human Genome-Wide CRISPR Library was ... designed to be small enough (~80,000 constructs) to enable convenient genome-wide "dropout viability" screens with most ...
  http://www.selectscience.net/cell-based-assays-+-in-vitro/product-directory/genetic-screens/?catID=1769&u=F9E1E535-116B-432B-B68F-932C8691DD2E
*  Plus it
2013) Whole-rat conditional gene knockout via genome editing. Nat Methods 10:638-640. doi:10.1038/nmeth.2516 pmid:23749298. ... 2010) Targeted genome modification in mice using zinc-finger nucleases. Genetics 186:451-459. doi:10.1534/genetics.110.117002 ... 2009) Knockout rats produced using designed zinc finger nucleases. Science 325:433. doi:10.1126/science.1172447 pmid:19628861. ... 1998) Cocaine self-administration in dopamine-transporter knockout mice. Nat Neurosci 1:132-137. doi:10.1038/381 pmid:10195128 ...
  http://www.jneurosci.org/content/38/8/1959
*  Application # 2017/0321212. SYSTEM FOR ISOLATING DNA MOLECULES - Patents.com
Genetic screens conducted with whole genome knockout collections such as the Yeast Knockout Collection (YKO)10 and the Keio ... In one implementation, the disclosed technology relates to a method for the construction of whole-genome knockout collections ... 0030] In one implementation, the disclosed technology can construct a curated, condensed, non-redundant whole-genome knockout ... whole-genome knockout collection. 8. The method of claim 7 wherein mutants of the progenitor collection catalog in singly- ...
  http://patents.com/us-20170321212.html
*  Lyudmila Nedyalkova - Free People Check with News, Pictures & Links - Yasni.com
Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout .... www.jolandavanleeuwen.com ... Evaluation and Design of Genome-Wide CRISPR/SpCas DOAJ. doaj.org. Lyudmila Nedyalkova Ryan Climie Leanne Tworzyanski Keith ... Evaluation and Design of Genome-Wide CRISPR NCBI - NIH. www.ncbi.nlm.nih.gov ... PICKLES: the database of pooled in-vitro CRISPR knockout library .... app.dimensions.ai ...
  http://www.yasni.com/lyudmila+nedyalkova/check+people
*  Addgene Blog: A Better Way to Share Science | Kendall Morgan
Lentiviral CRISPR Libraries Enable Genome-Scale, Knockout Screening. Posted by Kendall Morgan on Feb 20, 2014 11:57:00 AM ... But what if you want to study genes all across the genome? Two new human lentiviral CRISPR library systems described in ... "Whole regions of the genome which were not accessible before are now accessible using this technology." ...
  http://blog.addgene.org/author/kendall-morgan/page/5
*  The biological context of HIV-1 host interactions reveals subtle insights into a system hijack | BMC Systems Biology | Full Text
Integrating homolog mouse genome knockout data [17] with the HIV interactions reveals that HIV interacts with 376 (26.28%) ... using mouse genome knockout data as a suitable proxy for essentiality [17]. We assume that a human gene can be considered ... we can use mouse genome knockout data as a proxy for the importance of a gene in terms of a known phenotypic consequence in ... Genome Res. 2003, 13 (11): 2498-2504. 10.1101/gr.1239303PubMed CentralView ArticlePubMedGoogle Scholar. ...
  https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-4-80
*  CRISPR-Cas9 Genome Editing
CRISPR/Cas9 is becoming a most popular genome editing tool due to its simplicity, with guide RNA (gRNA or crRNA and tracrRNA) ... GenCrispr Genome Cleavage Detection Kit. CRISPR gRNA Libraries In-stock GeCKO libraries for genome-wide knock-out; SAM ... CRISPR-Cas9 Genome Editing. Genome-editing technologies have brought revolutionary progresses in numerous fields of biology. ... Powerful Service Platform to Accelerate Your Genome Editing Research. CRISPR KO/KI for Mammalian Cell lines Fully-validated KO ...
  https://www.genscript.com/CRISPR-Cas9-Genome-Editing.html?src=pullmenu
*  Creation and Preliminary Characterization of Pregnane X Receptor and Constitutive Androstane Receptor Knockout Rats | Drug...
2016) Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG ... 2013) Whole-rat conditional gene knockout via genome editing. Nat Methods 10:638-640. ... Here, we report the creation and preliminary characterization of PXR and CAR knockout rats and PXR/CAR double knockout rats. ... knockout. PCN. pregnenlone-16α-carbonitrile. PCR. polymerase chain reaction. PXR. pregnane X receptor. P450. cytochrome P450. ...
  http://dmd.aspetjournals.org/content/45/10/1068.full
*  Eating at the Table of Another: Metabolomics of Host/Parasite Interactions
In the Apicomplexa, due to their haploid genomes, knockout parasite lines are particularly well-suited for metabolomic studies ... Genome Biol. 2006;7:R17. [PMC free article] [PubMed]. *Cho K, Shibato J, Agrawal GK, Jung YH, Kubo A, Jwa NS, Tamogami S, Satoh ... Genome Biol. 2005;6:R26. [PMC free article] [PubMed]. *May P, Wienkoop S, Kempa S, Usadel B, Christian N, Rupprecht J, Weiss J ... Genome Biol. 2005;6:R49. [PMC free article] [PubMed]. *Blume M, Rodriguez-Contreras D, Landfear S, Fleige T, Soldati-Favre D, ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2825149/?lang=en-ca
*  Learning Labs
Specific applications of CRISPR to genome-scale knockout screening and locus-specific epigenetic editing approaches will also ...
  http://www.asbmb.org/meeting2017/workshops/learninglabs/
*  BMC Bioinformatics | Networks analysis
Optimal knockout strategies in genome-scale metabolic networks using particle swarm optimization Knockout strategies, ... Multiple network algorithm for epigenetic modules via the integration of genome-wide DNA methylation and gene expression data ... A mixed-integer linear programming approach to the reduction of genome-scale metabolic networks Constraint-based analysis has ... While some of the associated algorithms can be applied to genome-scale network reconstructions with several thousands of r... ...
  https://bmcbioinformatics.biomedcentral.com/articles/sections/networks-analysis?searchType=journalSearch&sort=PubDate§ion=Networks+analysis&page=2
*  Genome Editing of the Ascidian Ciona intestinalis with TALE Nuclease | SpringerLink
Ascidian Ciona intestinalis Genome editing TALEN Knockout Electroporation This is a preview of subscription content, log in to ... In: Hatada I. (eds) Genome Editing in Animals. Methods in Molecular Biology, vol 1630. Humana Press, New York, NY. * DOI https ... Particularly, knockout of genes in the G0 generation coupled with tissue-specific expression of TALENs enables us to rapidly ... Satou Y, Mineta K, Ogasawara M et al (2008) Improved genome assembly and evidence-based global gene model set for the chordate ...
  https://link.springer.com/protocol/10.1007%2F978-1-4939-7128-2_19