*  HLA-DR3 - Wikipedia
DR3 is genetically linked to HLA-DR52, DRB3*0202 allele, and HLA-DQ2 (DQ2.5). derived from IMGT/HLA Wiencke K, Karlsen TH, ... 2007). "Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes". Tissue Antigens. 69 (2): ... Pollack MS, Gold J, Metroka CE, Safai B, Dupont B (1984). "HLA-A,B,C and DR antigen frequencies in acquired immunodeficiency ... HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split 'antigens' serotypes. DR3 is a component gene-allele of the AH8.1 ...
  https://en.wikipedia.org/wiki/HLA-DR3
*  HLA-DR7 - Wikipedia
HLA-DR7 is genetically linked HLA-DR53, and is linked to DQ2 serotypes. There are a few interesting genetics with DR7. The A29- ... "The association between HLA class II haplotype with Graves' disease in Thai population". Tissue Antigens. 67 (1): 79-83. doi: ... HLA-DR7 (DR7) is a HLA-DR serotype that recognizes the DRB1*0701 to *0705 gene products. The serological reaction of DR7 is ... and disequilibrated components of DR7 show a tendency to be linked to A19 serotypes. derived from IMGT/HLA Wongsurawat T, ...
  https://en.wikipedia.org/wiki/HLA-DR7
*  Immunomodulatory plasticity of mesenchymal stem cells: a potential key to successful solid organ transplantation | SpringerLink
HLA-DR (human leukocyte antigen) [18].. Mesenchymal stem cells express intermediate levels of class I major histocompatibility ... adipose tissue and foetal tissues such as Wharton's jelly, placenta, amniotic fluid, umbilical cord (UC) and umbilical cord ... Rosová I, Dao M, Capoccia B, Link D, Nolta JA. Hypoxic preconditioning results in increased motility and improved therapeutic ... MSC modification: preconditioned or genetically modified. To overcome the current limitations, MSCs after isolation can be ...
  https://link.springer.com/article/10.1186/s12967-018-1403-0
*  Pathophysiology of Abdominal Aortic Aneurysm - Genetic Factors and Homocysteine Metabolism | IntechOpen
HLA) system is a genetically determined series of antigens that are expressed on leukocytes and tissues. They control a variety ... Other studies have shown HLA-DR B1*02 and B1*04 subtypes as well as HLA-A2 and HLA-B61 antigens to be more common in AAA ... Genetic links have been shown in the initiation and formation of abdominal aortic aneurysms (AAA). There have also been studies ... 47 - G. Monux, F. J. Serrano, P. Vigil, E. G. De La Concha, Role of HLA-DR in the pathogenesis of abdominal aortic aneurysm. ...
  https://www.intechopen.com/books/diagnosis-screening-and-treatment-of-abdominal-thoracoabdominal-and-thoracic-aortic-aneurysms/pathophysiology-of-abdominal-aortic-aneurysm-genetic-factors-and-homocysteine-metabolism/
*  A30-Cw5-B18-DR3-DQ2 (HLA Haplotype) - Wikipedia
March 2000). "HLA genes in Arabic-speaking Moroccans: close relatedness to Berbers and Iberians". Tissue Antigens. 55 (3): 239- ... Müller CR, Ehninger G, Goldmann SF (January 2003). "Gene and haplotype frequencies for the loci hLA-A, hLA-B, and hLA-DR based ... "The distribution of HLA class II haplotypes reveals that the Sardinian population is genetically differentiated from the other ... permanent dead link] Lilliu G., Le origini della storia Sarda: il Paleolithico e il Neollitico; l'età del rame;Eneolitico; la ...
  https://en.wikipedia.org/wiki/A30-Cw5-B18-DR3-DQ2_(HLA_Haplotype)
*  Type 1 Diabetes Mellitus: Practice Essentials, Background, Pathophysiology
Race-specific type 1 diabetes risk of HLA-DR7 haplotypes. Tissue Antigens. 2011 Nov. 78(5):348-51. [Medline]. [Full Text]. ... Polymorphisms of the class II human leukocyte antigen (HLA) genes that encode DR and DQ are the major genetic determinants of ... The investigators saw a significant link between each 1 mmol/mol rise in HbA1c and an increased rate of decline in z scores for ... In a genetically susceptible individual, viral infection may stimulate the production of antibodies against a viral protein ...
  https://emedicine.medscape.com/article/117739-overview
*  Type 1 Diabetes Mellitus Clinical Presentation: History, Physical Examination, Complications
Race-specific type 1 diabetes risk of HLA-DR7 haplotypes. Tissue Antigens. 2011 Nov. 78(5):348-51. [Medline]. [Full Text]. ... HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families. ... Clinical and experimental links between diabetes and glaucoma. Clin Exp Optom. 2011 Jan. 94(1):4-23. [Medline]. ... Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group. Diabetes. 2000 Oct. 49(10):1657-65. [Medline]. ...
  https://emedicine.medscape.com/article/117739-clinical
*  Plus it
Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet 2001; 68: 686- ... Interactions in hypoxic and hypercapnic breathing are genetically linked to mouse chromosomes 1 and 5. J Appl Physiol 2004; 97 ... Tissue Antigens 1991; 38: 24-30.. OpenUrlCrossRefPubMedWeb of Science ... DNA typing for HLA-DR, and -DP alleles in a Chinese population using the polymerase chain reaction (PCR) and oligonucleotide ...
  http://erj.ersjournals.com/content/36/3/577
*  Frontiers | A Novel Model on DST-Induced Transplantation Tolerance by the Transfer of Self-Specific Donor tTregs to a Haplotype...
... matched self-specific Tregs derived from the transfusion blood can be activated and multiply in the host by binding to antigen- ... matched self-specific Tregs derived from the transfusion blood can be activated and multiply in the host by binding to antigen- ... Once we discover how the details of the mechanisms involved are linked, we could be within reach of a procedure making it ... Once we discover how the details of the mechanisms involved are linked, we could be within reach of a procedure making it ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.00009/full
*  HLA-DQ6 - Wikipedia
HLA-DQ6 and DQB1*06 are almost synonymous in meaning. DQ6 β-chains combine with α-chains, encoded by genetically linked HLA- ... 1994). "HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR-RFLP method". Tissue Antigens. ... 2000). "HLA-DR and -DQ associations with insulin-dependent diabetes mellitus in a population of Turkey". Hum. Immunol. 61 (3): ... HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ (DQ) serotype group. The serotype is determined by the ...
  https://en.wikipedia.org/wiki/HLA-DQ6
*  HLA-DR15 - Wikipedia
DQB1*0501 haplotype is associated with systemic lupus erythematosus HLA-DR15 is genetically linked to HLA-DR51 and HLA-DQ6 (HLA ... 2007). "HLA alleles as predisposal factors for postmenopausal osteoporosis in a Greek population". Tissue Antigens. 69 (6): 592 ... HLA-DR15 (DR15) is a HLA-DR serotype that recognizes the DRB1*1501 to *1505 and *1507 gene products. DR15 is found at high ... DR15 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR16 antigens. Serotypes are unknown the ...
  https://en.wikipedia.org/wiki/HLA-DR15
*  RAG1 | Cancer Genetics Web
HLA-DR(+), CD86(+), CCR2(+), CCR5(+)) that were viable for 3 weeks in vitro. SmartDC/tWT1 were produced with peripheral blood ... for tumour tissue as compared to normal tissues. We have investigated here whether such retention is tumour specific.. METHODS ... Useful Links. RAG1. OMIM, Johns Hopkin University. Referenced article focusing on the relationship between phenotype and ... A genetically well-explored autologous mouse model for NBL is the TH-MYCN model. However, the immunobiology of the TH-MYCN ...
  http://www.cancerindex.org/geneweb/RAG1.htm
*  Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to...
HLA-DRhigh, and CD11c+ cells. Plasmacytoid DCs were identified as being Lin-1 negative, HLA-DRhigh, and either CD123 or BDCA2+ ... to pathogens and tumors while at the same time preventing immune responses against self-tissues or environmental antigens (1, 2 ... targeting immune complexes to DCs from mice genetically lacking inhibitory FcγRIIb can lead to enhanced generation of antigen- ... Abbreviations: DC, dendritic cell; FcγR, Fcγ receptor; ELISPOT, enzyme-linked immunospot. ...
  http://www.pnas.org/content/102/8/2910.full
*  HLA-DR12 - Wikipedia
... colorectal cancer HLA-DR12 is genetically linked to DR52 and HLA-DQ7 serotypes. derived from IMGT/HLA DR8 - 2% Gao X, Barnardo ... HLA-DR12(DR12) is a HLA-DR serotype that recognizes the DRB1*1201 to *1203, *1206. DR12 serotype is a split antigen of the ... Tissue Antigens. 40 (2): 90-7. doi:10.1111/j.1399-0039.1992.tb01965.x. PMID 1357780. Bidwell J, Soong T, Raymond P, Doherty D, ... "The association between HLA DR, DQ antigens, and vulval lichen sclerosus in the UK: HLA DRB112 and its associated DRB112/ ...
  https://en.wikipedia.org/wiki/HLA-DR12
*  HLA-DR16 - Wikipedia
HLA-DR16 is genetically linked to HLA-DR51 and HLA-DQ5 serotypes. derived from IMGT/HLA Cruz-Robles D, Reyes P, Monteón-Padilla ... Tissue Antigens. 67 (1): 79-83. doi:10.1111/j.1399-0039.2005.00498.x. PMID 16451208. Park M, Park Y, Song E, Park H, Kim T, ... HLA-DR16(DR16) is a HLA-DR serotype that recognizes the DRB1*1601, *1602 and *1604 gene products. DR16 is found in the ... DR16 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR15 antigens. DR16 is associated with ...
  https://en.wikipedia.org/wiki/HLA-DR16
*  HLA-DR17 - Wikipedia
The DRB1*0301/DRB1*1501 heterozygote is linked to primary Sjögren's syndrome HLA-DR17 is genetically linked to DR52 and HLA-DQ2 ... role of HLA-B8, −DRB1*0301, and −DQB1*0201 haplotype in clinical variations of the disease". Tissue Antigens. 70 (4): 301-6. ... HLA-DR17 (DR17) is an HLA-DR serotype that recognizes the DRB1*0301 and *0304 gene products. DR17 is found at high frequency in ... These serotypes are the result of gene products from the HLA-DRB3* and HLA DQA1*0501 and HLA DQB1*0201 alleles. DRB1*0301 is ...
  https://en.wikipedia.org/wiki/HLA-DR17
*  HLA-DR11 - Wikipedia
HLA-DR11 (DR11) is a HLA-DR serotype that recognizes the DRB1*1101 to *1110. DR11 serotype is a split antigen of the older HLA- ... DQB1*0301 haplotype is associated with hepatitis B virus persistence HLA-DR11 is genetically linked to HLA-DR52 and HLA-DQ7(3) ... Tissue Antigens. 40 (2): 90-7. doi:10.1111/j.1399-0039.1992.tb01965.x. PMID 1357780. Chou HT, Chen CH, Chen JY, Chang KC (2007 ... Hu C, Wu C, Lee C, Wu C, Tsai H, Chen P, Hsu P (2006). "HLA-DR11 and HLA-DR2 are negatively associated with autoantibody ...
  https://en.wikipedia.org/wiki/HLA-DR11
*  More Gluten Info.. start the printers | ConductDisorders - A soft place to land for battle weary parents.
triggering antigens. Dr. F.C.Dohan consistently advocated a gluten-schizophrenia. link. (Dohan FC Cereals and Schizophrenia: ... histocomptability antigens (self-markers) of the HLA-B8 and HLA-Dw3 types. This. genetic marker may indicate a predisposition ... and tissue damage. These circulating problems influence brain function in a variety of. undesirable ways. A family history of ... Celiac disease is genetically determined involving two or more concurrent. genes. The genes involved are part of the immune- ...
  https://www.conductdisorders.com/community/threads/more-gluten-info-start-the-printers.349/
*  HLA-DQ8 - Wikipedia
"Frequencies of HLA-A, HLA-B, HLA-DR, and HLA-DQ phenotypes in the United Arab Emirates population". Tissue Antigens. 66 (2): ... DQ8 β-chains combine with α-chains, encoded by genetically linked HLA-DQA1 alleles, to form the cis-haplotype isoforms. There ... Pimtanothai N, Hurley C, Leke R, Klitz W, Johnson A (2001). "HLA-DR and -DQ polymorphism in Cameroon". Tissue Antigens. 58 (1 ... HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 ...
  https://en.wikipedia.org/wiki/HLA-DQ8
*  Frontiers | Viral Impact in Autoimmune Diseases: Expanding the "X Chromosome-Nucleolus Nexus" Hypothesis | Immunology
The extracellular domain of the Epstein-Barr virus BZLF2 protein binds the HLA-DR beta chain and inhibits antigen presentation ... Among the viruses listed in Table 1, EBV has received the most attention as a virus with links to autoimmune diseases (15, 40 ... The tissue types in which viral sequestration occurs may vary, such as EBV behind the blood-brain barrier associated with MS or ... especially in genetically predisposed individuals, that establishes the conditions for eventual manifestation and progression ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.01657/full
*  HLA-DQ2 - Wikipedia
... high-resolution and large sample typing of HLA DR-DQ haplotypes in a sample of European Americans". Tissue Antigens. 62 (4): ... HLA-DQ2 and HLA-DQB1*02 are almost synonymous in meaning. DQ2 β-chains combine with α-chains, encoded by genetically linked HLA ... This isoform is partially encoded by the DQB1*02 genes in HLA-DQ2 positive individuals. DQB1*0201 is genetically linked to DQA1 ... Due to its link to coeliac disease, DQ2 has the highest association of any HLA serotype with autoimmune disease, close to 95% ...
  https://en.wikipedia.org/wiki/HLA-DQ2
*  Frontiers | Exploiting the Immunogenic Potential of Cancer Cells for Improved Dendritic Cell Vaccines | Immunology
... and HLA-DR, and the release of pro-inflammatory cytokines (Table 1). This led to the stimulation of high numbers of tumor- ... Two main approaches can be applied: loading with selected tumor antigens (tumor-associated antigens or tumor-specific antigens ... It has a two-step mode of action involving the selective uptake of a photosensitizer by the tumor tissue, followed by its ... Of note, in October 2015, the FDA approved the first oncolytic virus, Imlygic (a genetically modified live oncolytic herpes ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2015.00663/full
*  Method for identifying and validating dominant T helper cell epitopes using an HLA-DM-assisted class II binding assay - The...
Rational design of immunotherapeutics relies on clear knowledge of the immunodominant epitopes of antigens. Current methods for ... Tissue Antigens 51:467 (1998), incorporated hererin by reference.) The DR molecule may comprise HLA-DRB1, HLA-DRB2, HLA-DRB3, ... A modification site, such as a BirA modification site, can also be included in or linked to the soluble alpha and/or beta ... The DM α and β chains were genetically modified to possess the FLAG epitope (DYKDDDDK; SEQ ID NO:2) and the cMyc epitope ( ...
  http://www.freepatentsonline.com/8916340.html
*  Coeliac Disease | Technology Trends
typing for HLA-DQ and DR, the association with HLA-A1 and B8 was identified for coeliac disease in 1973 and dermatitis ... Further information HLA-DQ2 in coeliac disease and HLA-DQ2.5 in gluten immunochemistry Aside from the highly studied link ... Upon exposure to gliadin, and specifically to three peptides found in prolamins, the enzyme tissue transglutaminase modifies ... is an autoimmune disorder of the small intestine that occurs in genetically predisposed people of all ages from middle infancy ...
  http://www.primidi.com/coeliac_disease
*  CFTR Inhibitors for Treating Diarrheal Disease - Just another WordPress site
Epidemiological research have got uncovered that the largest hereditary risk elements for RA are specific alleles of the HLA-DR ... Meta-analysis provides proven that cigarette smoking is certainly one of the environmental elements linked with RA pathogenesis ... by bone tissue marrow-derived macrophages (23). These research demonstrated that ligation of SP-R210 with SP-A-BCG things ... they may react to self-antigens in the cause and joint autoimmunity; even so, the na?ve T cells (called Th0) initial need to ...
  http://teannualconference2015.info