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*  Monoclonal Antibody Therapy in Treating Patients With Primary Myelodysplastic Syndrome - Full Text View - ClinicalTrials.gov
MedlinePlus related topics: Myelodysplastic Syndromes Genetic and Rare Diseases Information Center resources: Myelodysplastic ... Syndrome. Myelodysplastic Syndromes. Preleukemia. Disease. Pathologic Processes. Bone Marrow Diseases. Hematologic Diseases. ... Monoclonal Antibody Therapy in Treating Patients With Primary Myelodysplastic Syndrome. This study has been withdrawn prior to ... DISEASE CHARACTERISTICS: Histologically confirmed primary myelodysplastic syndrome (MDS) with greater than 10% bone marrow ...
  https://clinicaltrials.gov/ct2/show/NCT00003984
*  Myelodysplastic syndrome: Genetic mutations & outcomes | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... for the treatment of patients with myelodysplastic syndrome (MDS)? ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://mdedge.com/hematologynews/quiz/4461/cellular-therapy/myelodysplastic-syndrome-genetic-mutations-outcomes?channel=195
*  Researchers Discover Genetic Origins of Myelodysplastic Syndrome Using Stem Cells | Bioethics Research Library
Researchers Discover Genetic Origins of Myelodysplastic Syndrome Using Stem Cells. (Eurekalert) - Induced pluripotent stem ... at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome (MDS) and ... reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer. The results appear in an upcoming ... cells (iPSCs) - adult cells reprogrammed back to an embryonic stem cell-like state-may better model the genetic contributions ...
  https://bioethics.georgetown.edu/2015/03/researchers-discover-genetic-origins-of-myelodysplastic-syndrome-using-stem-cells/
*  Molecular Genetic Investigation of Pediatric Myelodysplastic Syndrome - David Williams
Pediatric Myelodysplastic Syndrome (MDS) is a heterogeneous group of clonal stem cell disorders characterized by varying ... Molecular Genetic Investigation of Pediatric Myelodysplastic Syndrome Williams, David Lee Ebert, Benjamin Levine Fleming, Mark ... Pediatric Myelodysplastic Syndrome (MDS) is a heterogeneous group of clonal stem cell disorders characterized by varying ... 2015) Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity. ...
  http://grantome.com/grant/NIH/R24-DK094746-01
*  Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic...
... that stem and progenitor cells in MDS are characterized by stage-specific expansions and contain epigenetic and genetic ... dysfunction is presumed in myelodysplastic syndrome (MDS), the exact nature of quantitative and qualitative alterations is ... Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic ... Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic ...
  https://www.rdm.ox.ac.uk/publications/341226
*  Genetic profiling can guide stem cell transplantation for patients with myelodysplastic syndrome, study finds
... *Posted On 24 ... Home/Новини/Genetic profiling can guide stem cell transplantation for patients with myelodysplastic syndrome, study finds ... Researchers have long known that the specific genetic mutations within MDS patients' blood cells are closely related to the ... "Our findings offer physicians a guide - based on the genetic profile of the disease and certain clinical factors - to ...
  http://transplantology.org/genetic-profiling-can-guide-stem-cell-transplantation-patients-myelodysplastic-syndrome-study-finds/
*  Search | Page 6 | Aplastic Anemia and MDS International Foundation
Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview ... syndromes such as Fanconi anemia and receipt ... Chemotherapy in Treating Patients With Myelodysplastic Syndrome Before Donor Stem Cell Transplant (ICT-HCT) ... before donor ... More is better: Combination therapies for myelodysplastic syndromes ... histone deacetylase inhibitors, growth factors, and ... Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients ...
  http://www.aamds.org/search/node/chemotherapy?page=5
*  Hematology/Oncology Flashcards by Andrew Rivera | Brainscape
Causes: Genetic, Acquired (myelodysplastic syndromes), and Reversible (alcohol is most common; also lead, B6 deficiency, Cu ... T Cell ALL can present as mediastinal mass (presenting as SVC-like syndrome). Associated with Down Syndrome. Peripheral blood ... N = Nephrotic Syndrome. T = Transfusion Labs: Schistocytes, high fibrin split products (D-Dimers), low fibrinogen, low factors ... Reye Syndrome in children with viral infection. OD initially causes hyperventilation and respiratory alkalosis, but transitions ...
  https://www.brainscape.com/flashcards/hematology-oncology-3698361/packs/5585230
*  Molecular Pathogenesis of Myelodysplastic Syndromes | SpringerLink
Myelodysplastic syndromes (MDSs) are a collection of clonal stem cell hematopoietic disorders that are characterized by ... Genetic testing in the myelodysplastic syndromes: molecular insights into hematologic diversity. Mayo Clin Proc. 2005;80(5):681 ... bcl-2 expression and p53 accumulation in myelodysplastic syndrome, myelodysplastic-syndrome-derived acute myelogenous leukemia ... Angiogenesis in myelodysplastic syndromes. Br J Cancer. 1999;81:1398-1401.PubMedCrossRefGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4419-5698-9_33
*  News | McDonnell Genome Institute (MGI)
Genetic testing helps predict disease recurrence in myelodysplastic syndrome. September 25, 2018. September 25, 2018. ... Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, ... cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome ... pinpointing important genetic errors these deadly tumors have in common. The study lays the foundation for finding new ways to ...
  https://www.genome.wustl.edu/category/news/
*  Pathogenesis of multiple myeloma | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Myelodysplastic syndrome: Diagnosis, risk-stratification, and management. Take Quiz. Chronic myelomonocytic leukemia: Diagnosis ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ... Pathophysiology of antiphospholipid syndrome. Take Quiz. Current management of polycythemia vera & essential thrombocythemia. ...
  https://www.mdedge.com/hematologynews/quiz/4618/multiple-myeloma/pathogenesis-multiple-myeloma?channel=250
*  Cochrane Review: Red blood cell transfusion strategies | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Myelodysplastic syndrome: Diagnosis, risk-stratification, and management. Take Quiz. Chronic myelomonocytic leukemia: Diagnosis ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ... Pathophysiology of antiphospholipid syndrome. Take Quiz. Current management of polycythemia vera & essential thrombocythemia. ...
  https://www.mdedge.com/hematologynews/quiz/4340/clinical-guidelines/cochrane-review-red-blood-cell-transfusion-strategies?channel=306
*  Bacterial infections after bone marrow transplant | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Myelodysplastic syndrome: Diagnosis, risk-stratification, and management. Take Quiz. Chronic myelomonocytic leukemia: Diagnosis ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://www.mdedge.com/hematologynews/quiz/4468/cellular-therapy/bacterial-infections-after-bone-marrow-transplant?channel=195
*  Clonal hematopoiesis & risk for therapy-related cancer | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Myelodysplastic syndrome: Diagnosis, risk-stratification, and management. Take Quiz. Chronic myelomonocytic leukemia: Diagnosis ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ... Pathophysiology of antiphospholipid syndrome. Take Quiz. Current management of polycythemia vera & essential thrombocythemia. ...
  https://www.mdedge.com/hematologynews/quiz/4485/aml/clonal-hematopoiesis-risk-therapy-related-cancer?channel=253
*  Breast implant-associated anaplastic large cell lymphoma | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Myelodysplastic syndrome: Diagnosis, risk-stratification, and management. Take Quiz. Chronic myelomonocytic leukemia: Diagnosis ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ... Pathophysiology of antiphospholipid syndrome. Take Quiz. Current management of polycythemia vera & essential thrombocythemia. ...
  https://www.mdedge.com/hematologynews/quiz/7184/indolent-lymphoma/breast-implant-associated-anaplastic-large-cell-lymphoma
*  Indolent B-cell lymphoma: Autologous & allogeneic stem cell transplantation | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Myelodysplastic syndrome: Diagnosis, risk-stratification, and management. Take Quiz. Chronic myelomonocytic leukemia: Diagnosis ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ... Pathophysiology of antiphospholipid syndrome. Take Quiz. Current management of polycythemia vera & essential thrombocythemia. ...
  https://www.mdedge.com/hematologynews/quiz/4797/indolent-lymphoma/indolent-b-cell-lymphoma-autologous-allogeneic-stem-cell?channel=233
*  Hematolymphoid System | SpringerLink
Somatic genetic and epigenetic architecture of myelodysplastic syndromes arising from GATA2 deficiency. Blood. 2015;126(23):299 ... Myelodysplastic syndromes arising in patients with germline TP53 mutation and Li-Fraumeni syndrome. Arch Pathol Lab Med. 2010; ... Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Blood. 2013;122(21):521.Google Scholar ... Genetic features of myelodysplastic syndrome and aplastic anemia in pediatric and young adult patients. Haematologica. 2016;101 ...
  https://link.springer.com/chapter/10.1007%2F978-3-319-89626-7_6
*  Diagnosis and Prognosis: Molecular | SpringerLink
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Leukemia. 2014;28(2):241-7.PubMedCrossRef ... Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms. Blood. ... Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion. N Engl J Med. 2006;355(14):1456-65.CrossRefPubMed ... Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet. 2009;41(7):838-42.PubMedCrossRefPubMedCentral ...
  https://link.springer.com/chapter/10.1007%2F978-3-319-76879-3_2
*  Diagnosis & pathogenesis of primary CNS lymphoma | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://mdedge.com/hematologynews/quiz/3463/lymphoma-plasma-cell-disorders/diagnosis-pathogenesis-primary-cns-lymphoma?channel=242
*  Diagnosis of megaloblastic anemia | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://mdedge.com/hematologynews/quiz/3433/anemia/diagnosis-megaloblastic-anemia?channel=182
*  ASBMT Guidelines: Autologous progenitor cell transplant | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://mdedge.com/hematologynews/quiz/3928/clinical-guidelines/asbmt-guidelines-autologous-progenitor-cell-transplant?channel=225
*  Mycosis fungoides: Systemic implications & complications | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://www.mdedge.com/hematologynews/quiz/5496/indolent-lymphoma/mycosis-fungoides-systemic-implications-complications
*  Emergent conditions associated with multiple myeloma | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://mdedge.com/hematologynews/quiz/4921/multiple-myeloma/emergent-conditions-associated-multiple-myeloma?channel=250
*  Splenic marginal zone lymphoma: Features, diagnosis, & management | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://mdedge.com/hematologynews/quiz/4798/indolent-lymphoma/splenic-marginal-zone-lymphoma-features-diagnosis?channel=233
*  Guideline: Antithrombotic therapy for VTE, Part 2 | Hematology News
Myelodysplastic syndrome: Genetic mutations & outcomes. Take Quiz. Chronic myelomonocytic leukemia: Survival after transplant. ... Antiphospholipid antibody syndrome: Diagnosis & management. Take Quiz. Thrombotic thrombocytopenic purpura in adults. Take Quiz ...
  https://mdedge.com/hematologynews/quiz/4191/clinical-guidelines/guideline-antithrombotic-therapy-vte-part-2?channel=225